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Hesitancy and Acceptance of Covid-19 Vaccine on Pregnant Women in Southeast Sulawesi, 2021 Juminten saimin; Lianawati Lianawati; Monovalentino Monovalentino; Nur Indah Purnamasari; Steven Ridwan
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.23925

Background: ITAGI has recommended the provision of the COVID-19 vaccine for pregnant women. Women are more hesitant than men on the COVID-19 Vaccine Acceptance Survey in Indonesia. Purpose: To determine the acceptance and doubt about the COVID-19 vaccine in pregnant women. Methods: This was a descriptive study, which was carried out in July-August 2021. The sample was pregnant women in Southeast Sulawesi. Data retrieval using a survey technique with a questionnaire in the google form with informed consent on the first page. Results: Pregnant women who are willing to receive the COVID-19 vaccine voluntarily are 43.6%, undecided 34.1%, and 22.3% are not willing. For pregnant women who are not willing and hesitant to receive the vaccine voluntarily, 29.1% are willing if required and 70.9% are still not willing. If they get privileges, 56.4% are willing and 43.6% are still not. Pregnant women worry about their babies, 84.2% for mothers who are willing to be vaccinated and 77.9% for mothers who are unsure and not willing to be vaccinated. Concerned about their pregnancy, pregnant women who are willing to be vaccinated are 79.7% and those who are doubtful and unwilling are 75%. Those who doubt the safety of the vaccine are 36.6%. Around 51.5% of pregnant women want to consult with doctors and health workers. The most preferred places for vaccination are doctors/midwives/private hospitals (47.2%) and Puskesmas (42.7%). Most pregnant women widely used (83.6%) and desired (70.2%) social media to get information. Conclusion: Acceptance of the COVID-19 vaccine in pregnant women is low. There are concerns of pregnant women about pregnancy and their fetus, as well as doubts about their safety. Massive information needs to be provided by doctors and health workers through social media and others that can be accessed by pregnant women.Keywords: acceptance, COVID-19, doubt, pregnant women, vaccine

Analysis of Risk Factor Hypoalbuminemia on the Incidence of Hyponatremia in Children with Nephrotic Syndrome Waode Sitti Asfiah Udu
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25294

Background: Nephrotic syndrome is a clinical condition characterized by massive proteinuria, hypoalbuminemia, edema and may be accompanied by hypercholesterolemia. Proteinuria in childhood nephrotic syndrome is mainly in the form of albuminuria. In nephrotic syndrome, electrolyte balance disorders can occur in the form of hyponatremia which can cause complications from asymptomatic clinical manifestations to death. Currently, there are not many studies on hyponatremia in nephrotic syndrome. Objective: To determined hypoalbumin as a risk factor for hyponatremia in children with nephrotic syndrome. Methods: This research was an analytic observational study using a case control design. The subjects consisted of 80 children diagnosed with nephrotic syndrome at the Children's Health Installation at the Dr. Sardjito in Yogyakarta. The data collected included serum albumin levels and sodium levels. Statistical test using Odds Ratio (OR). .Results: The results showed that hypoalbumin (p = 0.000 ; OR 13,5; 95% CI 3,395 – 53,68) was a risk factor for the incidence of hyponatremia in children with nephrotic syndrome at the Children's Health Unit, Dr. Sardjito General Hospital in Yogyakarta. Conclusion: Hypoalbumin is a risk factor for hyponatremia in children with nephrotic syndrome

The Formulation and Antioxidant Activity Test of Binahong (Anredera cordifolia) Leaves Extract Lotion Hasty Hamzah; Yuyun Wirasasmita; Wa Ode Syafriah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.24014

Background: With current wide range of scientific research regarding the benefits of antioxidants, many has tried to invent new sources of this compound. The use of plant-based source for antioxidants recently become more and more popular, and one of these plants is Binahong (Anredera cordifolia). The leaves of these plant had been analyzed before to contain antioxidant compound. Objective: This research aimed to test, based on previous claim of antioxidant activity of Binahong (Anredera cordifolia) leaves. Methods: The lotion used was formulated using Tween 60 and Span 60 as its emulgator. After test, it was determined that the emulsion type is water in oil (w/o). Before Binahong Leaves extract were incorporated, the lotion was tested for physical stability including organoleptics, emulsion type, pH determination, homogeneity, and viscosity. Results: The analysis for antioxidant activity by DPPH method of Binahong leaves extract with various concentrations of 12,5 μg/mL, 25 μg/mL, 50 μg/mL, 100 μg/mL, 200 μg/mL, 400 μg/mL, yield a value of IC50 822.22 µg/mL (mild antioxidant activity level). This result corroborates previous findings with the same result. Meanwhile, the lotion containing Binahong leaves extract with various concentrations of 25 μg/mL, 50 μg/mL, 100 μg/mL, 200 μg/mL, 400 μg/mL, 800 μg/mL were analyzed with same method and yield a value of IC50 27041.50 µg/mL. Conclusion: The result proved there was a further loss of antioxidant activity after the extract were incorporated into lotion. Keywords: Formulation, Anredera cordifolia, Antioxidant, Antioxidant Lotion, Binahong,

Analysis of Leukocyte Count in Patients Acute Coronary Syndrome with ST-Segment Elevation and Acute Coronary Syndrome without ST-Segment Elevation at Kendari City General Hospital Jamaluddin Jamaluddin; Irawaty Irawaty; Fercee Primula
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25462

Background: Acute coronary syndrome (ACS) is an acute complication of coronary heart disease due to rupture of an atherosclerotic plaque, resulting in the formation of a thrombus, narrowing the lumen, resulting in impaired blood supply and decreased strength of heart muscle contraction. The occurrence of inflammation in the atherosclerotic process is characterized by an increase in the number of leukocytes, which causes increased leukocyte recruitment at the site of plaque rupture and is thought to play an important role in the incidence and prognosis of ACS. Purpose: The aim of this study was to determine the comparison of the number of leukocytes in STE and NSTE ACS patients. Methods: This research was an observational analytic study. The research design used a cross sectional study carried out at the Kendari City Regional General Hospital with the independent variable STE and Non STE ACS and the dependent variable was the leukocytes count. The number of samples was 73 patients. Data were collected from medical record data in accordance with the inclusion criteria. Bivariate analysis to compare the number of leukocytes using the unpaired T test. Results: Research from 73 respondents found that STE ACS patients had a mean leucocyte count of 10.31±3.50x103/μL while NSTE ACS patients had a mean leukocyte count of 8.62±3.43 x 103/μL (p=0,000). Conclusion: There was a significant difference of leukocyte count in STE ACS and NSTE ACS patients.

Validity of SQ-FFQ with FR 24 hour for measuring macro nutrient and total flavonoid dietary intake in reproductive age women with obesity Nina Indriyani Nasruddin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.24019

Background: Obesity has become a global epidemic with a threefold increase in cases since 1975. Dietary restriction that contains high calories, fat and also dietary interventions with natural bioactive foods such as flavonoids can prevent obesity. Assessment of intake for dietary regulation can use the Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ) and 24-hour Food Recall (FR) method Purposes: This study aimed to determine the average intake of macronutrients and total flavonoids using the SQ-FFQ and FR 24 Hr methods in women of childbearing age (WUS) with obesity and to knew the differences and correlations between the methods. Methods: a cross-sectional design was carried out from May to June 2021 in Kendari City. Samples were obtained through the purposive sampling technique as many as 30 WUS aged 18-49 years with a body mass index (BMI) ≥ 25 kg/m2. Data were collected through interviews to obtain information on macronutrient intake and total flavonoids using the SQ-FFQ and 24-hour FR questionnaire instruments. Anthropometric data was performed to assess nutritional status. The data were analyzed using the SPSS program through different tests and correlation tests. Results: The mean intake of macronutrients (energy, protein, fat, and carbohydrates) and total flavonoids using the SQ-FFQ method was higher than the 24-hour FR method. The different tests of the intake of energy, protein, carbohydrates, and total flavonoids using the SQ-FFQ method was significantly different from the 24-hour FR method (p<0.001). Fat intake was not significantly different between the two methods (p=0,267). The intake of energy, protein, fat, carbohydrates, and total flavonoids correlated by the two methods (p<0.05) with a correlation coefficient (r) of energy intake = 0.538, protein = 0.556, fat = 0.395, carbohydrates 0.665, and total flavonoids = 0.723. Conclusion: We conclude that The SQ-FFQ method is a valid tool to measure the intake of energy, protein, carbohydrates, fat and total flavonoids in obese women in women with obesity in the city of Kendari, Southeast Sulawesi, Indonesia.

Drug Management Quality During the Covid-19 Pandemic at Inpatient Health Centers in Kendari City Sabarudin Sabarudin; Sunandar Ihsan; Fifi Nirmala; Rifa’atul Mahmudah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25466

Background: WHO has declared Covid-19 a global pandemic after the infection case reached more than 121,000 cases. Puskesmas is the primary service closest to the community, so it has a significant role in dealing with COVID-19. The quality of health services at Puskesmas was influenced by drug management. On the other hand, the COVID-19 pandemic has resulted in changes in health services at Puskesmas. Hence, it is necessary to evaluate the quality of drug management at Puskesmas during the Covid-19 pandemic. Aims: This study aimed to evaluate the quality of drug management during the COVID-19 pandemic in all inpatient Puskesmas in Kendari City. Methods: This research was descriptive non-experimental, with retrospective data collection in all inpatient Puskesmas in Kendari City during the COVID-19 pandemic. Research subjects were indicators used by Satibi, and research objects include drug stock cards, LPLPO, RKO, and several other documents. The instruments used were observation sheets and interview guides. Results: All puskesmas were still active in proposing drugs to Fornas. The percentage of compliance of available drug items with Fornas, planning accuracy, conformity of requests, and the suitability of receipts was not up to standard. Storage according to dosage form, temperature, LASA, and FEFO were per standards, distribution accuracy, empty stock, insufficient stock, safe stock, the excess stock was not meet standards, and there were expired or damaged drugs. The suitability of the physical amount of the drug met the standard, but there were no inpatient health centers that conducted periodic drug management evaluations during 2020. Conclusion: The quality of drug management during the COVID-19 pandemic in all inpatient Puskesmas in Kendari City had not fully met the standards that have been set.

The Relationship Between Nutritional Status with Post Dural Puncture Headache Incident in Sectio Caesarea Patients with Spinal Anesthesi Agussalim Ali
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25289

Background: Post dural puncture headache (PDPH) is one of the most common complications of spinal anesthesia caused by leakage of cerebrospinal fluid (CSS) after anesthesia procedures. One of the factors that influence the incidence of PDPH is nutrional status where obese patients tend not to experience PDPH. This is based on an increase intraabdominal pressure in obese patients which can reduce CSF leakage in the epidural space. Purpose: Purpose of this study to determine whether there was a relationship between nutritional status and post dural puncture headache incident in sectio caesarea patients with spinal anesthesia at Aliyah 2 Hospital. Methods: This study used an observational analytic study with a cross sectional approach carried out at Aliyah 2 Hospital. The number of samples in this study was 51 people who were taken using total sampling technique. Data collection was obtained from medical records and filling out observation sheets for post-sectio caesarea patients with spinal anesthesia and then analyzed using the Fisher’s Exact Test. The dependent variable in this study was PDPH and the independent variables was the nutrional status. Result: This study showed that nutritional status (p = 0.007) had a significant relationship with the incidence of PDPH at Aliyah Hospital 2. Conclusion: From this study it could be concluded that the incidence of PDPH after spinal anasthesia is higher in patients with low BMI.

THE ASSOCIATION BETWEEN MATERNAL CHARACTERISTICS AND COMPLETENESS OF BASIC IMMUNIZATION SERIES AMONG TODDLERS IN KOTA AND JAMBULA PUBLIC HEALTH CENTERS IN TERNATE Azril Azril; Fera The; Abdul Hakim Husen
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.24071

Background: Immunization is the process of developing immunity towards against infectious diseases through vaccination. In 2019, the highest and lowest complete basic immunization coverage were achieved in Jambula (100%) and Kota (89%) public health centers, respectively. Maternal characteristics are considered to play role in basic immunization coverage among toddlers. Purpose: To identify the association between maternal characteristics and completeness of basic immunization among toddlers in the Kota and Jambula public health centers, Ternate. Method: Using purposive sampling, this analytical observational study was conducted in the Kota and Jambula public health centers, Ternate, in 2021. Results: From 192 samples, statistically significant associations were identified between maternal education, knowledge, and attitudes, with the completeness of basic immunizations (p<0,05). No significant associations were detected with maternal age and maternal work. Conclusions: Maternal education, knowledge, and attitudes may affect the completeness of basic immunizations among toddlers. The need for sound programs and parental education regarding complete basic immunizations among toddlers might be crucial.Keywords: immunization, maternal characteristics, Kota Public Health Center, Jambula Public Health Center

Correlation of Climate Factors, Population Density, and Larva Free Rate (ABJ) on the Incidence of Dengue Hemorrhagic Fever (DHF) in Kendari City Period 2012-2021 Fifi Nirmala; Nur S Layaly; La Ode Liaumin Azim
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25471

Background: Dengue Hemorrhagic Fever (DHF) is an infectious disease that is endemic in most tropical areas in the world and around 3.5 billion people live in areas where dengue is endemic. A large number of individuals residing in a certain area will facilitate the spread of dengue disease and accelerate the transmission of dengue virus from vectors. Climate is very important for the survival of the Aedes Aegypti mosquito because mosquito breeding sites will increase along with climate change. ABJ shows the density of larvae in an area. Purpose(s): This study aimed to determine the correlation of climate factors, population density, and larva free rate (ABJ) to the incidence of Dengue Hemorrhagic Fever (DHF) in Kendari City in 2012–2021. Methods: This research method was a cross sectional design and Spearman rank correlation analysis using SPSS application. The data used are secondary data in the form of data on rainfall, humidity, temperature, population density, and the incidence of DHF in a period of 10 years (2012-2021) and ABJ in a period 2016 - 2020. Results: The results of this study indicated that the rainfall variable (p value = 0,000, r = 0,416) and the humidity variable (p value = 0,000, r = 0,446) have a sufficient and unidirectional correlation coefficient to the incidence of DHF in Kendari City in 2012-2021, ABJ variable (p value = 0,014, r = -0,949) has a very strong and non-unidirectional correlation coefficient on the incidence of DHF in Kendari City in 2016-2020, and there is no correlation between the temperature variable (p value = 0,087) and the variable population density (p value = 0,651) with the incidence of DHF in Kendari City in 2012-2021. Conclusion: There was a correlation between rainfall and humidity variables on the incidence of DHF in Kendari City in 2012-2021, there was a correlation between the ABJ variable and the incidence of DHF in Kendari City in 2016-2020, and there wasn’t a correlation between temperature variable and population density variable on the incidence of DHF in Kendari City in 2012-2021.

Characteristic Test and Antihyperuricemia Activity of Ethanol Extract Stem of Etlingera rubroloba A.D Poulsen In vitro Asriullah Jabbar; Idin Sahidin; Khansa Rafida Triaqilah; Mubarak Mubarak; Muhammad Ilyas Yusuf
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 9, No 2 (2022)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v9i2.25290

Background: Etlingera rubroloba (E. rubroloba) A.D Poulsen is one of the endemic plants of Southeast Sulawesi, which has the largest species in the world. Local people widely use this plant as traditional medicine. Many of these plant species have been previously reported as antioxidants, antibacterials, and others. However, for E. rubroloba, there are still very few reports from a pharmacological aspect, especially anthiperuricemia. Objective: This study was conducted to determine the characteristics and activity of the ethanol extract of the stem of E. rubroloba A.D Poulsen in vitro. Methods: The stems of E. rubroloba A.D Poulsen were extracted with ethanol solvent by maceration, then the filtrate obtained was evaporated using an evaporator to get an ethanol extract. Furthermore, the extract characterization test was carried out, including water content, ash content, water-soluble extract content, and ethanol-soluble extract content. Then the antihyperuricemia activity test in vitro using the Xanthine Oxidase (XO) kit. Results: The results of the characteristic test showed that the ethanolic extract of E. rubroloba contained 5.15% water content, 5.485% ash content, 55.2% water-soluble extract content, and 56.52% ethanol-soluble extract content. Furthermore, the antihyperuricemic activity of the ethanol extract of E. rubroloba was IC50 48.59 ± 0.03 g/mL and Allopurinol 42.21 ± 0.02 g/mL as positive controls. Conclusion: E. rubroloba stem ethanol extract has characterization results according to the literature, has antihyperuricemia activity, and is a reference for the development of traditional drugs

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Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

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Kota kendari,

Sulawesi tenggara

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Sulastrianah

Contact Email sulastrianahmuhtadi@gmail.com

Phone +6285242541601

Journal Mail Official sulastrianahmuhtadi@gmail.com

Editorial Address Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location Kota kendari, Sulawesi tenggara INDONESIA

Abstract

Abstract

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Abstract

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Abstract

Contact Name
Sulastrianah

Contact Email
sulastrianahmuhtadi@gmail.com

Phone
+6285242541601

Journal Mail Official
sulastrianahmuhtadi@gmail.com

Editorial Address
Kampus Hijau Bumi Tridharma Anduonohu Kendari Universitas Halu Oleo Fakultas Kedokteran

Location
Kota kendari,

Sulawesi tenggara

INDONESIA