cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Agus Chalid
Contact Email
gulid.p@gmail.com
Phone
+6285220013654
Journal Mail Official
gmhc.unisba@gmail.com
Editorial Address
Jalan Hariangbanga No. 2, Tamansari, Bandung 40116
Location
Kota bandung,
Jawa barat
INDONESIA
Global Medical and Health Communication
Published by Universitas Islam Bandung
ISSN : 23019123     EISSN : 24605441     DOI : https://doi.org/10.29313/gmhc
Core Subject : Health, Science,
Dentistry Health Professions Immunology & microbiology Nursing Public Health
Global Medical and Health Communication is a journal that publishes research articles on medical and health published every 4 (four) months (April, August, and December). Articles are original research that needs to be disseminated and written in English. Subjects suitable for publication include but are not limited to the following fields of anesthesiology and intensive care, biochemistry, biomolecular, cardiovascular, child health, dentistry, dermatology and venerology, endocrinology, environmental health, epidemiology, geriatric, hematology, histology, histopathology, immunology, internal medicine, nursing sciences, midwifery, nutrition, nutrition and metabolism, obstetrics and gynecology, occupational health, oncology, ophthalmology, oral biology, orthopedics and traumatology, otorhinolaryngology, pharmacology, pharmacy, preventive medicine, public health, pulmonology, radiology, and reproductive health.
Arjuna Subject : Kedokteran - Epidemilogi
Articles 18 Documents
 1   2 
Search results for , issue "Vol 12, No 3 (2024)" : 18 Documents clear
Autism Spectrum Disorder: a Two-center Evaluation of Pharmacological Intervention and Behavioral Therapies on Core Symptoms Solek, Purboyo; Gamayani, Uni; Rusmil, Kusnandi; Afriandi, Irvan; Prasetya, Taufan; Rizqiamuti, Anggia Farrah; Nurfitri, Eka; Burhan, Burhan; Sahril, Indra; Gunawan, Kevin
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14460

Abstract

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by chronic deficits in social communication and interaction, with sensory processing abnormalities affecting over 90% of individuals across different sensory areas. This study investigated the combined effects of aripiprazole and behavioral therapy (BT) on core symptoms of ASD in children aged 6–10. Utilizing the considerable neuroplasticity still present at this age, we hypothesized that this combined approach might yield superior outcomes compared to BT alone. The 12-week randomized, double-blind, placebo-controlled trial was conducted from February 2023 to January 2024 at two sites of Child Development Centers in Bandung city, involving 51 participants (22 intervention, 29 placebo). The intervention group received aripiprazole and BT, while the placebo group received saccharum lactis and BT. Both groups underwent BT comprising applied behavioral analysis (ABA) and discrete trial training (DTT). The Childhood Autism Rating Scale (CARS) assessed treatment effects. The independent 2-sample t-tests and Mann-Whitney tests showed no significant differences in overall CARS scores between groups. However, the analysis revealed significant improvements in three subcategories: VII (visual response, p=0.021), IX (taste-smell-touch response, p=0.035), and X (fear or nervousness, p=0.043). These findings suggest that the combined approach may enhance sensory processing and emotional regulation in children with ASD. The study highlights the potential benefits of a multimodal approach to ASD treatment, combining targeted pharmacological intervention with behavioral therapies. However, limitations such as study duration and sample size warrant further research to optimize treatment strategies for individuals across the autism spectrum.
Polymorphisms of RS7055763 and RS41307258 in TBX22 Gene Haplotype as Risk Factors for Non-syndromic Cleft Palate Indonesian Deutero-Malay Population Susanti, Nita; Ullah, Irfan; Sulaksono, Haura Labibah Salsabil; Nasroen, Saskia Lenggogeni; Maskoen, Ani Melani
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.13677

Abstract

Non-syndromic cleft palate (NS-CP) is a multifactorial congenital malformation affected by genetic and environmental factors. The incidence of non-syndromic cleft lip with or without cleft palate (NS-CLP) varies considerably between ethnic groups and geographical regions. TBX22 is a crucial determinant for the formation of intramembranous bone in the posterior hard palate. Therefore, TBX22 is fundamental to palatogenesis and supports normal palate progress. The rs7055763 and rs41307258 polymorphisms in the TBX22 gene are associated with risk factors for NS-CP in the Indonesian Deutero-Malay population. In the previous study, NS-CP still needed to be investigated in the Deutero-Malay population. However, there are different races, mainly for the Deutero-Malay population. This study aims to determine whether rs7055763 and rs41307258 polymorphisms in the TBX22 gene are risk factors for NS-CP in the Deutero-Malay population. This study was conducted in Terpadu Laboratory, Faculty of Dentistry, Universitas Padjadjaran, from February until June 2023. The design of this study was a case-control study. The DNA patient samples were obtained from saliva and whole blood. Moreover, DNA is extracted, and the rs7055763 and rs41307258 segments are analyzed using PCR and Sanger sequencing. PCR data was analyzed by chi-square testing. In this study analysis, polymorphisms of rs7055763 (G>A) and rs41307258 (T>A) in the TBX22 gene show no significant differences between case and control groups, namely 0.911 and 0.645, respectively. However, the genotype in the rs41307258 shows the p-value as 0.027, indicating substantial differences and the OR is 1.390. In conclusion, the rs7055763 and rs41307258 polymorphisms in the TBX22 gene do not appear to be risk factors for developing NS-CP in the Indonesian Deutero-Malay population.
COVID-19 Treatment Patterns in Patients with Acute Respiratory Failure at Dr. Hasan Sadikin General Hospital Bandung in 2021–2022 Rohmawaty, Enny; Sumardi, Aklila Qurrota Aini; Kulsum, Iceu Dimas
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14073

Abstract

Acute respiratory failure is the most common complication and cause of death in COVID-19 patients. The COVID-19 medication has yet to be discovered. COVID-19 treatment guidelines are constantly being updated. This study aims to determine the COVID-19 treatment patterns in patients with acute respiratory failure at Dr. Hasan Sadikin General Hospital Bandung in 2021–2022. This retrospective, descriptive study used systematic random sampling to examine medical records of COVID-19 patients with acute respiratory failure at Dr. Hasan Sadikin Central General Hospital between June 2021 and June 2022. Gender, age, length of stay, outcome, comorbidities, and pharmacological and non-pharmacological treatment data were analyzed by SPSS software. This study included 120 COVID-19 patients with acute respiratory failure, with the majority of patients are male (55.83%), 30–60 years old (55.83%), length of stay of 1–3 days (52.5%), and have disease severity at severe condition (43.33%) and one comorbidity (37.5%). Patients mostly received non-rebreathing oxygen mask (54.2%), antiviral remdesivir (83.3%), corticosteroid dexamethasone (76.7%), enoxaparin anticoagulants (61.7%), a combination of vitamin C, vitamin D, and multivitamins (45.8%), and two antibiotics (33.3%). Additional treatments include tocilizumab (0.8%), intravenous immunoglobulin (2.5%), and convalescent plasma (0.8%). Statistical analysis shows that patients who stay at the hospital longer, have less or no comorbidities, and are given oxygen therapy have a significant possibility of recovering. Treatments commonly prescribed to COVID-19 patients with acute respiratory failure are antivirals, corticosteroids, anticoagulants, vitamins, and antibiotics, while the administration of oxygen therapy has a significant probability of recovery.
Correlation between Length-to-width Ratio of Gallbladder and Gamma-glutamyl Transferase Value in Biliary Atresia Elmanar, Ryan; Violetta, Lenny; Setiawati, Rosy
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14170

Abstract

Biliary atresia represents one of the most prevalent etiologies for neonatal cholestasis. Unmanaged biliary atresia can be fatal. Ultrasonography is the primary diagnostic test because it's accurate, cost-effective, and available. Various ultrasound findings can assist in diagnosing biliary atresia; the length-to-width ratio of the gallbladder is a particularly advantageous method, offering a short examination time, objectivity, and ease of use, with an accuracy rate of 78.9%. In cases with unconventional ultrasound findings, gamma-glutamyl transferase is believed to be able to complete the diagnostic process with an accuracy rate of up to 80%. The optimal cut-off value differs between studies, making it challenging to use as a benchmark for biliary atresia detection. In this study, researchers aim to further investigate the relationship between length-to-width ratio and gamma-glutamyl transferase in cases of biliary atresia, compared to the liver biopsy results in these patients and the optimal cut-off. This study employed an observational analytic approach with a retrospective design. The sample population consisted of all patients with neonatal cholestasis who underwent laboratory and ultrasonographic examinations at Dr. Soetomo Academic General Hospital Surabaya between 2019 and 2023. The study population comprised 82 patients. A significant relationship (p-value<0.001) was observed between the length-to-width ratio of the gallbladder and biliary atresia, as well as between gamma-glutamyl transferase and biliary atresia (area under the curve: 0.7–0.8). However, the analysis between the length-to-width ratio of the gallbladder and the value of gamma-glutamyl transferase showed p-value=0.066, which means no significant relationship was observed between the length-to-width ratio and gamma-glutamyl transferase.
Association between Clinical Characteristics of Pregnant Women in the Third Trimester and Low Back Pain Dewi, Mira Dyani; Rachmawati, Meike
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.13889

Abstract

Pregnancy is a physiological condition characterized by growth in both the fetus and the mother. Various biomechanical, physiological, and structural changes in pregnant women cause body posture changes, impacting low back pain (LBP). In the third trimester, LBP pain felt by pregnant women is usually accompanied by activity limitations and a decreased quality of life. This study aimed to determine the association between the clinical characteristics of pregnant women in the third trimester and low back pain. This research was conducted at the Department of Obstetrics and Gynecology and Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital, Bandung from June to December 2017. The method is observational analysis with a cross-sectional approach with a sample of pregnant women in their third trimester who complained of lower back pain and lived in Bandung. According to the findings, the majority of pregnant women with LBP in the third trimester were under the age of 35 (33 of 38), had multiparous parity (25 of 38), had normal pre-pregnancy weight (21 of 38), gained an average of 11.28 kg during pregnancy, and had a median pain intensity of 5. Age was the only factor significantly correlated with LBP pain intensity; parity and weight gain during pregnancy did not. The study concludes a significant association between age in the third trimester of pregnancy and the intensity of LBP pain. Still, no significant association was found between parity and weight gain during pregnancy with the intensity of LBP pain.
Relationship of Physical Activity and Vitamin D Levels in Elderly Women Lorensia, Amelia; Jalmav, Marthy Meliana Ariyanti; Suryadinata, Rivan Virlando; Akbar, Muhammad Reza Aprililo
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.13499

Abstract

Older adults are at risk of vitamin D deficiency, especially in older women, due to a decrease in the hormone estrogen, which causes decreased bone density and increased risk of fractures. There is a relationship between vitamin D deficiency and lack of physical activity due to the storage of vitamin D in adipose tissue. Physical activity was measured using the International Physical Activity Questionnaire (IPAQ). The aim was to determine the relationship between physical activity and vitamin D in elderly women. This cross-sectional analytic observational study was conducted at Nursing Home X in Surabaya city from May to August 2023. The variables were physical activity (measured by IPAQ to estimate physical activity levels) and vitamin D level (measured by VIDAS® instrument to determine 25(OH) levels). The subjects were all women aged ≥60 years. The sampling technique uses the purposive sampling method. For an analysis of the relationship between physical activity levels and vitamin D levels, the Pearson correlation test was used with a ratio data scale. This research received 49 respondents. The average physical activity level was 1316.82±720.90, and most respondents had a moderate physical activity level of 44.90%. Vitamin D levels were ≤30 ng/ml for 46 respondents (93.87%). The results of the Pearson correlation test were obtained with a rvalue=0.089 and a significance value (Sig.) of 0.542. There was no significant correlation between physical activity and vitamin D levels. Other factors such as age, health conditions, and vitamin D intake can affect the results. Further research can be developed into measurements to examine physical activity in old age.
Associated Tinnitus Risk Factors in Patients with Type 2 Diabetes Mellitus Puryani, Noorma Zuliana; Yenny, Yenny
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14151

Abstract

Tinnitus risk factors for type 2 diabetes mellitus (T2DM) are still under debate. Our study objective was to find tinnitus prevalence and principal risk factors in community-dwelling T2DM subjects. It was an analytical observational cross-sectional design study conducted from August to October 2023 at a public health center in West Jakarta. The consecutive non-random sampling method included 140 ambulatory T2DM study subjects. Tinnitus Screener and Tinnitus Handicap Inventory assessed tinnitus presence and severity. Age, sex, T2DM duration, fasting and 2-hour post-prandial blood glucose concentrations, lipid profile, blood pressure, and severity of hypertension were extracted from medical records. Data analysis was by chi-squared or Fisher exact tests, followed by multiple logistic regression analysis, with statistical significance set at p<0.05. The subjects' mean age was 54.71±5.33 years, and T2DM duration was 8.75±2.55 years. Tinnitus prevalence was 92 (65.17%), with 44 subjects (47.8%) having moderate tinnitus. Multivariable logistic regression findings: age (p=0.576), T2DM duration (p=0.116), total cholesterol (p=0.053), HDL-cholesterol (p=0.425), hypertension (p=0.046). Hypertension increased the risk of tinnitus by 2.289 times in T2DM subjects after adjusting for age, T2DM duration, and total and HDL cholesterol. Hypertension is the main tinnitus risk factor. The high tinnitus prevalence in our T2DM subjects requires regular screening for auditory function and control of blood pressure to minimize tinnitus risk in T2DM subjects.
Ergonomic Risk Level of Work Posture in Leather Shoes Industry Ekawati, Ekawati; Setyaningsih, Yuliani; Kurniawan, Bina; Wahyuni, Ida
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14031

Abstract

Posture while working will influence work results and have a health impact on workers. Rapid upper limb assessment (RULA) is a method for analyzing work posture on the job using the upper part of the body. This research examines the risk level of work postures in the leather shoe industry. This research was conducted in the leather shoe industry located in Semarang. This research uses the RULA method to assess the risk level of work postures. Body area measured by RULA was divided into two groups, namely group A (arms, forearms, hands) and group B (neck, body). The RULA score is obtained based on observing the worker's body posture, including neck, arms, back, legs, and load. The observed scores are then converted into final RULA scores. It was found that the body posture of workers in the leather industry was at a score of 6 and 7. This score has implications for the need for further research regarding the body posture of the following workers. Work posture correction must be done immediately to prevent further health impacts.
The Impact of Social Value Orientation on Pro-environmental Behavior Yanuvianti, Milda; Srisayekti, Wilis; Fitriana, Efi
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.14217

Abstract

Promoting pro-environmental behavior is a significant concern nowadays. Researchers have identified social value orientation as one of the key factors influencing pro-environmental behavior. This study aims to investigate the influence of social value orientation on pro-environmental behavior and to highlight differences based on gender. The research method used is non-experimental quantitative causality. This research was carried out in 2024 at B University in Bandung. The study participants were 378 students from B University in Bandung, selected using convenience sampling. The measurement tools used were the Triple Dominance Scale by Van Lange (1998) to assess social value orientation (SVO) tendencies and the GEB Scale by Kaiser (2020) to measure general ecological behavior, i.e., the tendency to engage in pro-environmental or non-pro-environmental behavior. Data analysis was done using JASP version 19. The results showed a significant influence of social value orientation on pro-environmental behavior with Fisher's exact test p=0.017 (p<0.05). An odds ratio of 0.084 was obtained, indicating that participants categorized as pro-social are 11.9 times more likely to engage in pro-environmental behavior than those classified as pro-self. Regarding gender differences, the chi-square test revealed no significant differences between males and females in terms of social value orientation tendencies with χ2=0.056 (p>0.05), as well as in terms of engaging in pro-environmental behavior, with χ2=0.774 (p>0.05). The conclusions of this study are that social value orientation affects pro-environmental behavior, and there was no significant difference between gender in social value orientation tendencies and pro-environmental behavior.
Promotion of Crypt-like Structures in Intestinal Organoid Development through the Addition of Graphene Oxide in Cell-based Assays Sulaksono, Haura Labibah Salsabil; Kamilah, Mutiara Mila; Faridah, Lia; Joni, I Made; Watanabe, Kozo; Ekawardhani, Savira
Global Medical & Health Communication (GMHC) Vol 12, No 3 (2024)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v12i3.13386

Abstract

The intestinal organoid represents a miniature organ that can mimic functional physiology and pathology. However, there are several challenges to developing the organoid system, such as the limited survival of cells. Based on theory, matrix addition is a factor that can support survival in cells. As a result, graphene oxide (GO) addition is used in this study. As an artificial matrix, GO has been successfully shown to encourage good cell behavior and is well known for having good biocompatibility. Herein, we fabricate GO characterized with FT-IR and PSA. Crypt-like structures (CLS) are isolated from small intestinal mice in GO addition as a matrix. The gene expression and cell viability of CLS are investigated. RT-PCR examined the gene expression in CLS, while cell viability of CLS was carried out using the staining method. This study was conducted at FiNder U-CoE and Parasitology Laboratory of HSE Universitas Padjadjaran Bandung during February and December 2023. Our results show that Vil-1 as an identity for cells in the intestinal epithelium has been expressed in CLS primary significantly higher than intestinal tissue (p=0.01). However, identifying Lgr5 in CSL isolates is tricky. Thes in the crypt may be limited. Besides that, cell viability of CLS with GO addition can be maintained for four days. The GO addition as a matrix may provide support to maintain CLS. These findings are promising as cell-based assays for developing organoid models.

Page 1 of 2 | Total Record : 18

 1   2 

Filter by Year

2024 2024


Reset
Filter By Issues
All Issue Vol 13, No 1 (2025) Vol 12, No 3 (2024) Vol 12, No 2 (2024) Vol 12, No 1 (2024) Vol 11, No 3 (2023) Vol 11, No 2 (2023) Vol 11, No 1 (2023) Vol 10, No 3 (2022) Vol 10, No 2 (2022) Vol 10, No 1 (2022) Vol 9, No 3 (2021) Vol 9, No 2 (2021) Vol 9, No 1 (2021) Vol 8, No 3 (2020) Vol 8, No 2 (2020) Vol 8, No 1 (2020) Vol 7, No 3 (2019) Vol 7, No 2 (2019) Vol 7, No 1 (2019) Vol 6, No 3 (2018) Vol 6, No 2 (2018) Vol 6, No 1 (2018) Vol 5, No 3 (2017) Vol 5, No 2 (2017) Vol 5, No 1 (2017) Vol 4, No 2 (2016) Vol 4, No 1 (2016) Vol 3, No 2 (2015) Vol 3, No 2 (2015) Vol 3, No 1 (2015) Vol 3, No 1 (2015) Vol 2, No 2 (2014) Vol 2, No 2 (2014) Vol 2, No 1 (2014) Vol 2, No 1 (2014) Vol 1, No 2 (2013) Vol 1, No 2 (2013) Vol 1, No 1 (2013) Vol 1, No 1 (2013) More Issue