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UNEJ e-Proceeding
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Articles 1,005 Documents
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FORMULATION AND OPTIMIZATION OF CARBOPOL AND ETHYL CELLULOSE AS FLOATING-MUCOADHESIVE SYSTEM OF DILTIAZEM HYDROCHLORIDE TABLET BY FACTORIAL DESIGN Eka Deddy Irawan; Lusia Oktora Ruma Kumala Sari; Andreas Henry Prasetyo
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Hypertension is a degenerative disease that eachyear has increased the number of patients. Numberof patients in Indonesia is estimated at 15 millionpeople. Nearly 50% of patients suffering fromhypertension are not aware that tends to be severehypertension (Syahrini et al., 2012).Diltiazem Hydrochloride (HCl) is an antihypertensivedrug used 3-4 times a day with doses of 30-60 mg(UBM Medica, 2012). Diltiazem HCl has a half life of3-5 hours (Sweetman, 2009) with the mainabsorption area in the upper stomach (Kapil et al.,2012) that can be formulated into sustained releasedosage gastro retentive system.The system created is a combination of floatingmucoadhesive.The combination of these systems isexpected to overcome the shortcomings of thesystem when used alone. Floating system floats overthe surface of gastric contents when the stomach isfull but at the time stomach is emptied and thetablet reaches the pylorus the bouyancy of thedosage may be decreased. If the stomach is full,mucodhesive dosage form not properly adheres maybe passage the pylorus due to peristalticmovements of the stomach (Gaykar et al., 2013).Polymer is one of the essential ingredients toproduce a floating-mucoadhesive system that meetsthe requirements. The polymer used is acombination of Carbopol and ethyl cellulose. Thecombination of hydrophilic and hydrophobicpolymers proved able to control the rate of drugrelease with high solubility (Nanjwade et al., 2011).
STRATEGI PRIORITAS PERBAIKAN KUALITAS BATIK LUMAJANG SEBAGAI IKON DAERAH BERDASARKAN PERSEPSI DAN HARAPAN MASYARAKAT DI KABUPATEN LUMAJANG Hesti Budiwati
UNEJ e-Proceeding Dinamika Global: Rebranding Keunggulan Kompetitif Berbasis Kearifan Lokal
Publisher : UPT Penerbitan Universitas Jember

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Batik is a legacy of indigenous peoples in Indonesia, which in ancient times could only be used by the royal family or the nobility alone. The facts show that batik is now a public fashion trends. The existence of batik is still relatively stagnant and less able to thrive. Therefore, the study aims to determine the strategy of quality improvement priority to batik Lumajang that the government and businesses batik Lumajang can take action priorities for the development of batik Lumajang be better. The approach used in this research is Lean Six Sigma, with a sample of 60 people Lumajang. They will be asked them to comment on batik Lumajang based on perceptions, expectations and their interests. On the basis of perceptions, expectations, and concerns of Lumajang that is structured batik Lumajang quality improvement priority areas of Lumajang as icons. The results of research, there are 5 (five) priority quality improvement batik Lumajang should precedence, that are (1) The design and product diversity batik, (2) The Batik ability to absorb perspiration, (3) The understanding of the quality of raw materials batik, (4) The quality color durability, and (5) The raw material quality batik where people yearn to raw material quality batik Lumajang.
UNDERWEIGHT AND MORBIDITY STATUS AMONG UNDER FIVE YEARS CHILDREN IN SURABAYA Triska Susila Nindya; Lailatul Muniroh
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Under five years old children is one of the group thatvulnerable to under nutrition, moreover this agegroup also susceptible to infectious disease due totheir immunity and their activity related to exposureof infectious disease. To achieve optimal growth, achildren must obtain adequate dietary intake,optimal care practice that include appropriatefeeding practices and less frequent of infectiousdisease (Black et al, 2008). Inadequate food intaketo Undernutrition among under five childrenbecome important issue since it can affect shortterm and also long term that go beyond child hood(Neufeld and Osendarp, 2014). Indonesia BasicHealth Survey revealed there was fluctuation ofunderweight prevalence from 18.4% in 2007,decreased to 17.9% in 2010 and increased to 19.6%in 2013 (Indonesia Basic Health Survey, 2013). Thereis a strong evidence that undernutrition thatoccurred during the first two years of life contributeto the increasing risk of non communicable diseasein the later life (Victora et al, 2008). Communicabledisease is one of the factors that contribute tonutritional status, particularly underweight inchildren since underweight is the indicator thatreflect an acute disturbance of nutritional status.Communicable diseases that often occur in childrenare diarrhea and upper respiratory infecti on. Indeveloping countries, diarrhea contributes to thechildhood morbidity and mortality, as it estimatedthat 1.5 million child die to diarrhea per year (Roy etal, 2011). There is a bidirectional relationship ofdiarrhea and malnutrition in children with themechanism of diarrhea episodes lead to anorexia,absorptive function impairment, the damage ofmucosal and the increase need of nutrients (Brown,2003). Malnutrition also increase the incidence andseverity of acute respiratory infection throughmechanism of immunity impairment, particularly incellular immunity (Bhutta et al, 1998). This studyaimed to analyze the association of underweight andmorbidity of diarrhea and acute respiratory infectionin under five years old children.
PEMBERDAYAAN EKONOMI MASYARAKAT MELALUI PENGEMBANGAN MODEL DESA KONSERVASI DAN EKOWISATA DI KAWASAN TAMAN NASIONAL MERU BETIRI Hari Rujito
UNEJ e-Proceeding Dinamika Global: Rebranding Keunggulan Kompetitif Berbasis Kearifan Lokal
Publisher : UPT Penerbitan Universitas Jember

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This study aims to (i) assess the effectiveness of the development of Model Villages Conservation (MDK) and ecotourism in the area around the national park which is a strategy of economic empowerment in the region TNMB and (ii) to compile a "Road Map" that correspond to the development of community empowerment in each village conservation and ecotourism in the area TNMB. The method used is a method of quantitative and qualitative methods TEV PRA (Participatory Rural Appraisal). The location of research is in the area of Meru Betiri which includes three (3) sections: Section Area I Sarongan (Rajegwesi), Section Ambulu Region II and Region III Section Rajegwesi and Kalibaru (Kebunrejo). The results showed the achievement of community development activities in Banyuwangi TNMB is pretty good, whereas in the region for achieving results TNMB Jember mediocre and still needs to be improved.
EFFECTIVENESS OF BINTARO (Cerberra odollam Gaertn.) LEAF ETHANOLIC EXTRACT AGAINST Staphylococcus aureus IN-VITRO BIOFILM FORMATION Filania S. Kanja; Lisa Soegianto; Sumi Wijaya
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Biofilm is a structural form of a group ofmicroorganisms protected by matrik extracellularcalled Extracellular Polymeric Substance (EPS),where EPS is a product produced by thesemicroorganisms itself and as a shelter from thebad influence in environment. The structure ofthese matrix is strings which cross each otherwhich can be adhesive for biofilm4).Biofilm from Staphylococcus aureus seen inchronicle infection cases as ulcer on diabeticsfoot, venous statis ulcer and pressure sores.Patients with infection wound with chronicleulcer in vein feet found positive culture ofStaphylococcus aureus as much as 88-93,3% froma number of infection found.Figure 1. Cerberra odollam Gaertn.Bintaro can be used as an analgesic,anticonvulsant, kardiotonik and antihypertensive2).The aim of this study is to test the effectivenessof the ethanol extracts of bintaro leaves (Cerberraodollam Gaertn.) towards the Staphylococcusaureus formation by in vitro.MATERIALSBintaro leaves (Cerberra odollam Gaertn.),Staphylococcus aureus culture ATCC 6538, petridish, ose wire , micro pipet, autoclave (AllAmerican Model No 25x, USA), incubator(Memmert and Binder, Germany), Laminar AirFlow (LAF) (Type V-130, Indonesia), microplate,microplate reader (Thermofisher Scientific,America), vacuum rotary evaporator (BÜCHI,Germany), weight analytic (Sartorius TE 214 S,Germany), oven (Memmert, Germany).
IRON TABLETS DISTRIBUTION OF PREGNANT WOMAN IN THE DISTRICT AND CITY OF EAST JAVA PROVINCE Soenarnatalina Melaniani
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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According to WHO (2008), Maternal Mortality Rate(MMR) is one success indicator of health servicesin a country. Maternal death can occur due toseveral reasons, such as anemia. Iron deficiency isa major cause of anemia in pregnant womencompared with a deficiency of other nutrients.Anemia is a health problem experienced by womenaround the world, especially in developingcountries.World Health Organization (WHO) reported thatthe prevalence of pregnant women who have irondeficiency is around 35-75% and thus increase inaccordance of the gestation. According to theWHO, 40% of maternal deaths in developingcountries are associated with anemia in pregnancyand most of anemia in pregnancy is caused by irondeficiency and acute bleeding, or both.Riskesdas data in 2013 indicate that there are25.3% of the total number of pregnant women inEast Java or around 24 people pregnant womensuffer from iron deficiency anemia duringpregnancy. The health of pregnant women need tobe improved in order to achieve the fifth MDGs, itshould be highly considered about the distributionof Fe tablets 30 and tablets 90, as well as the K1and K4 visit by pregnant women.Distribution of Fe tablet 30 and tablets 90 indistrics and cities need to be compared using thestatistic test namely T-test while to find the effectof tablet Fe 30 tablets in the K1 pregnancy visit andthe effect of tablet Fe 90 tablets in K4 pregnancyvisit by using regression.Research purposes :1. To analyze the differences between distributionof Fe tablets 30 and Fe tablets 90 ini districs andcities.2. To analyze the effect of Fe tablets 30 in K1pregnancy visit and the effect of the Fe tablets 90in K4 pregnancy visit, also its effectiveness in EastJava Province.Benefits of the research :Improve maternal health with the equality on thedistribution of Fe tablets 30 and Fe tablets 90 ineach districs and cities.
CORPORATE GOVERNANCE, PROFITABILITAS, DAN NILAI PERUSAHAAN Gusni .; Agnes Vinelda
UNEJ e-Proceeding Dinamika Global: Rebranding Keunggulan Kompetitif Berbasis Kearifan Lokal
Publisher : UPT Penerbitan Universitas Jember

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This study aims to examine the effect of corporate governance (board of director, board of commissioner composition, and institutional ownership), profitability (return on asset and net profit margin) on firm value in mining industry, and knowing which variables having powerful effect on the firm value. This research is using secondary data, such as the financial reports, annual reports and other related information of mining industry. To achieve the aims of this research, a total of 20 companies of mining industry listed in Indonesia Stock Exchange were selected using purposive sampling technique from the period of 2010 to 2014. A panel data regression analysis technique has been conducted The research result shows that only profitability variable measured by return on asset (ROA) has a positive and significant effect on the firm value, whereas the other profitability variable measured by net profit margin has a negative and significant effect to the firm value. Meanwhile, corporate governance measured by board of director, board of commissioner composition, and institutional ownership not significantly impact on the firm value in mining industry.
POSISI EKSPOR-IMPOR INDONESIA DALAM MEA (SEBUAH STUDI KOMPARATIF) Tria Apriliana
UNEJ e-Proceeding Dinamika Global: Rebranding Keunggulan Kompetitif Berbasis Kearifan Lokal
Publisher : UPT Penerbitan Universitas Jember

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The aim of this study was to determine the position of Indonesia in facing Asean Economic Community (AEC) from the view of export and import compared to nine other member countries of AEC and to determine the difference between Indonesia’s export and import value before and after the implementation of AEC until the third quarter of the first year. Variables in this study was formed based on literature study. This study used secondary data, namely information related to import-export and in the Central Bureau of Statistics, World Bank, World Development Indicators and ASEAN Statistics. The comparative analysis of one-way ANOVA was used to test the differences in import-export  among the ten member countries of AEC and paired t-test was used to test the differences in import-export Indonesia before and after the implementation of AEC. The results of this study indicated that there are significant differences between export and import among ten member countries of AEC. The results also showed that there is no significant difference between Indonesia's exports before and after the enactment of AEC, but there are significant differences between the import of Indonesia before and after the implementation of AEC.
CHARACTERIZATION AND THE RELEASE TEST OF ANTI-AGING TRETINOIN IN NANOEMULSION USING OLIVE OIL Tristiana Erawati M.; Widji Soeratri
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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People are more and more desire a youthful andattractive appearance. Aging of the skin can be theresult of a normal process that involves a lowerrate of metabolic activities and is calledchronologic aging. Photoaging is the consequenceof chronic sun exposure and manifests clinicallywith fine and coarse wrinkling, roughness, dryness,laxity, shallowness, pigmentary mottling,telangiectasia, and in some cases withpreneoplastic and neoplastic changes (Stefanaki etal., 2005). Tretinoin is a compound that is able toshow an effect of prevention and treatment ofwrinkles due to photo aging, acne, andinflammation of the skin. It is all-trans retinol isoxidized through retinal to its most activemetabolite (Kligman et. al, 1986). The effectivity ofan active ingredient is determined among othersby the ability to reach the site of action. To reachthe site of action the active ingredients used orallyor topically must first dissolve, release thenabsorbed or penetrates through the membraneand then diffuses into the site of action. Tretinoinpractically insoluble to increase it usednanoemulsion delivery as a vehicle. Solubility isone of the factors of drug absorption. Highersolubility of drug caused higher amount of drug toabsorb. Smaller droplet of emulsion caused rapiddrug release. In this study tretinoin loaded innanoemulsion using olive oil than it characterizedand test of tretinoin release compared withtretinoin in emulsion. Olive oil used as oil phase innanoemulsion as known it widely used in cosmetic.MATERIAL AND METHODSResearch MaterialsTretinoin (PT. Cortico Mulia), olive oil , Tween 80(Sigma Aldrich), Span 80 (Sigma Aldrich), ethanol96 % (E-Merck), NaH2PO4 (E-Merck) and Na2HPO4(E-Merck), aquademineralisata (PT Brataco).Research InstrumentsStirrer plate (Dragon Lab MS-Pro), ultrasonic(Branson 3510), shaker machine (Wine shake), pHmeter (Eutech Instruments pH 700), particleanalyzer (Delsa Nano C), Franz diffusion cell withcellophane membranes, spectrophotometer(Shimadzu UV-1800), Transmission ElectronMicroscopy (TEM-type JOEL JEM-1400), lightmicroscope.
APPLICATION OF STANDART NURSING LANGUAGE (NANDA, NOC. NIC) USING SOCIAL MEDIA: INSTAGRAM® TO INCREASE INFORMATION SEEKING BEHAVIOUR AND MOTIVATION OF NURSING STUDENT Deni Yasmara; Sartika Wulandari
UNEJ e-Proceeding Proceeding of 1st International Conference on Medicine and Health Sciences (ICMHS)
Publisher : UPT Penerbitan Universitas Jember

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Abstract

Many research on information and technology wascommonly conducted at university and hospital. Inthe other hand the usage of electronic resourcesespecially usage of electronic journal in highereducation has been not expected (Setiawan, 2008)Student on university using electronic resources forlearning and seeking information. In the otherhand, Social Media e.g INSTAGRAM® increasing foryear to year and more famous for Nursingstudents. Social media became the newest trendfast within the communication sector. The Socialmedia grows usage in indonesia are one the fastestgrowth of technology. The “one to many” became“many to many” as indonesian internet interactionquickly adapt the new technology (Lesmana, 2012)The usage of INSTAGRAM® like an electronicjournal by Nursing student for seeking informationabout NANDA,NOC,NIC in Universitas Airlangga.The aim of this study was to find the effectivity ofapplication of Standart Nursing Language (SNL)NANDA, NOC, NIC using social media :INSTAGRAM® for increasing information seekingbehaviour and motivation of Nursing students. Thesocial media instagram has been build byresearcher as a lecture. The name of social mediaaccount was “ WECARECREATIVE_”

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