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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
Arjuna Subject : -
Articles 298 Documents
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Pattern of disease and type of operation of Surgical Site Infection in obstetrics and gynecology at Dr Soetomo Hospital, Surabaya, Indonesia Ardi Eko Marsanto; Kuntaman Kuntaman; Hari Paraton; Budi Prasetyo
Majalah Obstetri dan Ginekologi Vol. 27 No. 2 (2019): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (455.374 KB) | DOI: 10.20473/mog.V27I22019.49-55

Abstract

Objectives: to find correlation between risk factors and classification of SSI, the distribution of SSI, and cost in Soetomo Hospital.Materials and Methods: descriptive retrospective observational with correlation analysis between risk factors and SSI classification according to Centers for Disease Control (CDC) definition with univariate analysis. Sub-group descriptive analysis on microbiology result, length of stay (LOS) and cost was also performed. All patients was diagnosed SSI between January 2015 until June 2017.Results: age, referral cases, Body Mass Index, Hemoglobin and Albumin results, types of surgery, types of case are the risk factors we included. Analysis result shows no strong and significance correlation in all risk factors (r 0.053 – 0.447; p 0.072 – 0.971). According to SSI types, the distribution are: superficial (7; 13.2%), deep (26; 49.1%), organ/space (20; 37.7%). Extended-Spectrum Beta-Lactamase (ESBL) was obtained in 19 (14 Obstetrics; 5 Gynecology) from 28 patients with microbiology results. Five deaths occured in ESBL patients (1 Obstetrics; 4 Gynecology; ratio 1 : 11.2). Mean length of stay in Obstetrics and Gynecology was 41.7 and 19.2 days, respectively. Mean cost per day in Obstetrics and Gynecology was 1.2 amd 2.6 million rupiah, respectively.Conclusions: no strong and significant results in all risk factors. Death rate in SSI and malignancy with positive ESBL result are high. Less cost needed for SSI patients, but with longer LOS. Comprehensive approaches are needed to patients at risk of SSI, further study with larger sample are needed.
Characteristics of gestational thropoblast tumor in Dr. Soetomo Hospital, year 2015-2017 Yoan A Angelina; Poedjo Hartono
Majalah Obstetri dan Ginekologi Vol. 27 No. 2 (2019): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (302.219 KB) | DOI: 10.20473/mog.V27I22019.79-83

Abstract

Objectives: To report the characteristics of the patients of Gestational Trophoblastic Neoplasia (GTN) and its management at Dr. Soetomo Hospital, Surabaya, Indonesia.Case Report: There were 41 cases GTN at dr. Soetomo hospital within 3 years, data were collected from January 2015 to December 2017, which are 11 cases develop drug resistance.Conclusion: GTN is a chemosensitive neoplasia but can also experience resistance to chemotherapy. It is important to monitor the levels of beta-HCG for at least 12 months before the patient can get pregnant again.
FR 50% in pregnancy results in different neuron and glial cell count (astrocytes, olygodendrocytes, and microglia) in the cerebrum and cerebellum of newborn Rattus norvegicus Fitria Desky; Hermanto Tri Joewono; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 27 No. 2 (2019): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (466.498 KB) | DOI: 10.20473/mog.V27I22019.56-65

Abstract

Objectives: To analyze the difference neuronal and glial (astrocytes, oligodendrocyte, microglia) cell count in cerebrum and cerebellum of Rattus norvegicus newborns with 50% food restriction and control group.Materials and Methods: This was an analytical experimental study with single blind randomized post test only control group design using animals subjects Rattus norvegicus. This study was conducted at Animal laboratory, Veterinary Faculty, Universitas Airlangga. Animal subjects were divided into FR50% group and control. Neuron and glial (astrocytes, oligodendrocytes, microglia) counts were analyzed using comparison test, with CI 95%.Results: There was a significant difference in cerebrum and cerebellum neuron cell count between intervention and control group (9.88+3.59 vs 16.88+2.553; p=0.000 and 7.5+1.789 vs 11.44+4.56; p=0.02). There was no difference in cerebrum and cerebellum glial cell count. There was a significant difference in cerebellum astrocyte between intervention and control group (80.94+24.255 vs 59.69+18.77; p=0.02) but no difference in cerebrum. There was a significant difference in cerebrum and cerebellum oligodendrocyte between intervention and control group (14.06+12.195 vs 25.13+8.609; p<0.000 and 13.63+6.712 vs 24.00+8.862; p=0.001), and there were significant difference in cerebrum and cerebellum microglia cell between intervention and control group (5.25+3.435 vs 4.94+3.838; p=0.620 and 8.81+4.119 vs 5.25+1.483; p=0.004).Conclusion: Food Restriction 50% (FR50%) in Rattus norvegicus decreased cerebrum and cerebellum neuron cell and oligodendrocyte count and increased cerebrum and cerebellum microglial count.
Risk of meningioma associated with exposure of hormonal contraception. A case control study Wahyuhadi, Joni; Heryani, Dini; Basuki, Hari
Majalah Obstetri & Ginekologi Vol. 26 No. 1 (2018): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (196.511 KB) | DOI: 10.20473/mog.V26I12018.36-41

Abstract

Objective: To determine the effect of hormonal contraceptive exposure on the development of meningioma. Materials and Methods: This case–control study, conducted in 2016, included all patients diagnosed histopathologically with meningioma between 2012 and 2013 and treated at Dr. Soetomo General Hospital, Surabaya, Indonesia. Medical record data from these patients were collected and compared with a control group consisting of non-meningioma patients who underwent contrast-enhanced head CT scans and direct interviews. A total of 101 cases and 101 controls were analyzed. Data were evaluated using univariate logistic regression analysis. Results: Patients with a history of hormonal contraceptive use had a 12.31-fold higher risk of developing meningioma (p = 0.000). In this study, women using monthly injectable contraceptives or oral contraceptive pills demonstrated a lower risk of meningioma compared to those using three-month injectable contraceptives. Participants who had used hormonal contraception for more than 10 years had an 18.216-fold increased risk of developing meningioma (p = 0.000). Histopathological analysis revealed no significant association between hormonal contraceptive history and meningioma subtype distribution; however, descriptive data indicated that the transitional type was the most frequent histopathological subtype among the case group. Conclusion: There is a significant association between hormonal contraceptive use and the occurrence of meningioma, particularly with the use of three-month injectable hormonal contraception and long-term use exceeding 10 years. No significant association was observed between meningioma histopathological grade and a history of hormonal contraceptive exposure.
Green tea extract reduces insulin level and folliculogenesis in insulin-resistant PCOS rats model Irma Maya Puspita; Budi Santoso; Budi Utomo
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.103-107

Abstract

Objectives: Polycystic ovary syndrome (PCOS) is an endocrine disorder with still unknown pathophysiology. Insulin resistance is one of major factors that affect the pathogenesis of PCOS (69%). Green tea has compounds that can be used to improve the condition of insulin resistance, so that folliculogenesis may recur in the case of PCOS.Materials and Methods: The subjects in this study were rats which were divided into 5 groups, consisting of 2 groups serving as a control group (negative and positive) and 3 groups as the treatment group. Each group consisted of 7 experimental animals. Negative control group was given with distilled water for 14 days. Positive control group was given with injections of testosterone propionate 1 mg/100 g BW intramuscularly in the thigh for 28 days to obtain a model of insulin-resistant PCOS and the distilled water was used as therapy. The treatment groups were given wth injections of testosterone propionate 1 mg/100gBW intra-muscularly for 28 days and then treated with green tea extract in doses of each 200 mg/kg, 400 mg/kg, and 800 mg/kg for 14 days. Rats were dissected on day 42 for harvesting the right and left ovary and heart blood sample was taken for examining insulin levels.Results: The results showed that administration of green tea extract on K5 can reduce insulin levels and increase folliculogenesis significantly (significance p <0.05).Conclusion: Green tea extract can reduce insulin levels and increase folliculogenesis in rats. PCOS - Insulin resistance at a dose of 800 mg/kg.
Relationship between BMI and β-hCG levels with hyperemesis gravidarum in Manado, Indonesia Inne Mamesah; Maria Loho; Eddy Suparman
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.108-113

Abstract

Objectives: The main objective of this study was to determine the relationship between BMI and β-HCG levels with hyperemesis gravidarum.Materials and Methods: This study was a case control study which compares between BMI and β-Hcg levels of patients with hyperemesis gravidarum and without hyperemesis gravidarum. This study was conducted at Obstetric and Ginecology Department of Medical  Faculty of Sam Ratulangi University in Manado. This study was conducted on September - November 2018 and participated by 33 pregnant women with hyperemesis gravidarum and 33 pregnant women without hyperemesis gravidarum which were included in accordance to the inclusion criteria and signed the informed consent to participate in this study.Results: The percentage of patients with Hyperemesis Gravidarum within the age group of 20 -35 years old were 23 patients (69.69%). The highest number of patients without Hyperemesis Gravidarum were [VL1] within age group of 20 - 35 years old as many [VL2] as 28 patients (84.84%). Hyperemesis Gravidarum was found the most in normal BMI group, which was 26 patients (78.78%). The patients without hyperemesis gravidarum were also found in the highest number in the normal BMI group, 21 patients (63.63%). T-test showed that there was no significant difference in BMI of group with postive HEG and negative HEG (p = 0.027). Spearman Correlation Test had been conducted to show relationship between β-hCG levels, and there was a strong correlation between gestational age and β-Hcg levels (r = 0,764 ; p = 0,000), which means β-hGG level increased along with gestational age.Conclusion:There was significant relationship between β-hCG and Hyperemesis Gravidarum. There was also a significant relationship between gestational age and β-hCG Levels which mean the increase of β-hGG level is along with the increase of gestational age. Tere was no significant relationship between BMI and Hyperemesis Gravidarum.
Roots and Wings: Indonesia´s way to improvements of women´s health care Hans-Gerd Meerpohl
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.90-93

Abstract

Indonesia is the world’s fourth most populous nation and the largest economy in Southeast Asia. The World Bank recently classified Indonesia as an emerging middle-income country. Enormous gains have been made in poverty reduction, cutting the poverty rate to more than half since 1999, to 9.8% in 2018.(1) However, based on March 2017 data, approximately 20 % of the entire population remain vulnerable of falling into poverty, as their income hover marginally above the national poverty line.(2) Unique challenges for Indonesia´s health care system reflects the fact that approximately 250 million inhabitants from more than 300 ethnic groups spread over 17.000 islands. Indonesia has set itself an ambitious goal of establishing universal health care by 2019, a move commended by the United Nations as part of the 2030 Sustainable Development Goals.(SDGs)  Women´s health care, including women’s empowerment and gender equality, is concerned as an especially important issue because - on a global scale- it is one area in which performance has been seen by many to be slow. (3) While Indonesia has experienced greater success in its efforts to reduce the under five mortality rate (27 per 1.000 live births in 2015), efforts to tackle maternal mortality has been less effective as rates have continued to persist above 125 per 100.000 live births over the past decade (6) Having some of those facts in my mind I started my visit to Indonesia and to Surabaya in October 2018 with the desire to understand in the end the country, the people and their health system challenges a bit better.
New vesicovaginal fistula formation in a rabbit model Eighty M Kurniawati; Tri HS Hadi; Nur AR Widiatmoko; Widjiati Widjiati; Fedik A Rantam; Budi Santoso; Budi I Santoso; Hari Paraton; Gatut Hardianto; Azami D Azinar; Boedi Setiawan
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.114-118

Abstract

Objective: To create an animal model of vesicovaginal fistula as a modality to develop therapy.Material and Methods: This study was an preliminary experimental study to create new fistula vesicovaginal formation in a rabbit model. Six female New Zealand white rabbits of Stem Cell Research and Development Center of Universitas Airlangga were used in this study and were divided into 3 groups in which there were 2 rabbits in each group. Vesicovaginal fistula formation was performed through laparotomy surgery. After the abdomen is opened, the Nasogastric tube is inserted vaginally into the anterior vaginal wall. The incision is made on the anterior vaginal wall and the posterior wall of the bladder. The Nasogastric tube that comes out of the vagina is inserted into the bladder incision to maintain the formation of vesicovaginal fistula. Both mucosal walls are sutured and tested to determine if there is any leak. Evaluation the model of vesicovaginal fistula was carried out 3 weeks postoperatively according the group.Result: Four out of six rabbits have formed vesicovaginal fistulas, which are from groups two and three. There are no complications during the treatment period until terminationConclusion: Rabbits have the potential to become experimental animals for the vesicovaginal fistula model. The best time to release a nasogastric tube to maintain a fistula is 2 weeks.
Length of marriage to pregnancy and the risk of preeclampsia Khusnul Putri Maharani; Atika Atika; Ernawati Ernawati
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.94-98

Abstract

Objective: to analyze the relationship between the length of marriage to pregnancy with the incidence of preeclampsia.Materials and Methods: This study was an observational analytic study with case control approach. Samples were 33 respondents with preeclampsia and 66 respondents with normal pregnancy, all were primigravida with age of 20-35 years old in Dr. M. Soewandhie Hospital, Surabaya, Indonesia, in January-June 2017. Data were taken from medical record.Results: This study found that the length of marriage until pregnancy was 0-4 months with percentage of 39.4% and 77.3% for case and control group respectively. Chi-square test resulted in p = 0.00 and contingency coefficient = 0.366, which meant there was relationship between the length of marriage to pregnancy and the incidence of preeclampsia in primigravida in Dr. M. Soewandhie Hospital Surabaya from January to June 2017 despite being in low level. The value of odd ratio (OR) was 0.191 (95% CI 0.077-0.473), which means there was a risk of protection for the length of marriage to pregnancy <4 months against the incidence of preeclampsia.Conclusion: The shorter the length from early marriage to pregnancy in primigravida, the lower the risk for developing preeclampsia.
Correlation of CTR1, ERCC-1, and HSP70 expressions with cisplastin response in cervical cancer stage IIB Brahmana Askandar; Suhatno Suhatno; Juliati Hood
Majalah Obstetri dan Ginekologi Vol. 27 No. 3 (2019): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V27I32019.119-132

Abstract

Objectives: This study aimed to determine the resistance of cisplatin (chemotherapy drugs) at three point areas including expression of CTR1, ERCC1, and HSP70 in cervical cancer patients.Materials and Methods: This research used a cross sectional approach. The population in this study were patients with stage IIB of cervical carcinoma. The study sample were patients with stage IIB of cervical carcinoma according to the FIGO classification, patients received cisplatin chemotherapy treatment (50 mg/m2 4 times), had good kidney and liver function. The independent variables in this study were the expression of CTR1, ERCC1, and HSP70 and the dependent variable of this study was the response to cisplatin therapy in cervical cancer. Primary data was obtained through MRI examination after the administration of cisplatin 50 mg/m2 every week. The parameters of this study included the expression of CTR1, ERCC1 and HSP70. Data obtained were analyzed using Wilcoxon rank test, Spearman test and categorical regression with a significance level of p <0.05.Results: The treatment of cisplatin therapy in cervical cancer patients had no significant correlation between the expression of CTR1 and ERCC1, but in the expression of HSP70 there was a significant negative correlation which means that the higher the expression of HSP70, the worse the response of therapy.Conclusion: This study showed that HSP70 expression can be used as an indicator in treatment of cisplatin therapy in cancer patients through MRI examination.

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