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Optimization of Biocompatibility of Natural Polymer Hydrogels for Targeted Drug Delivery Applications Ava Lee; Jaden Tan; Rachel Chan
Journal of Biomedical and Techno Nanomaterials Vol. 1 No. 4 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jbtn.v1i4.1763

Abstract

This study aims to optimize the biocompatibility of natural polymer hydrogels for targeted drug delivery applications. Crosslinking modifications are applied to natural polymers such as alginate, agarose, and chitosan, with the aim of increasing cell viability and reducing cytotoxicity. The results showed that modified hydrogels had higher cell viability (85–90%) and lower cytotoxicity compared to unmodified hydrogels. In addition, these modifications do not trigger immunological or inflammatory reactions in the cells of the human body tested. This study suggests that the crosslinking technique can be an effective solution in developing more biocompatible natural polymer hydrogels, which can be used for targeted drug delivery applications. However, for broader clinical applications, further research is needed to explore other modification methods and test more types of polymers.
The Role of Business Incubators in Facilitating the Growth of Creative Startup Companies Ava Lee; Jaden Tan; Rachel Chan
Journal of Social Entrepreneurship and Creative Technology Vol. 1 No. 4 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jseact.v1i4.1731

Abstract

The rise of creative startups has become an important phenomenon in today’s entrepreneurial landscape. These companies, often operating in industries such as design, media, technology, and entertainment, play a crucial role in driving innovation and economic growth. Business incubators have emerged as key players in supporting the development and growth of these startups by providing essential resources, mentoring, and networking opportunities. However, the specific role and impact of business incubators on creative startups remain underexplored, particularly in the context of their long-term growth and sustainability. This study aims to examine the role of business incubators in facilitating the growth of creative startup companies. It seeks to understand how incubators contribute to the development of creative industries by providing both tangible and intangible support to entrepreneurs. The research adopts a mixed-methods approach, utilizing both qualitative interviews with incubator managers and creative entrepreneurs and quantitative surveys to assess the impact of incubator support on startup performance. Data was collected from several business incubators in key startup hubs. The findings indicate that business incubators play a critical role in providing creative startups with access to funding, mentorship, networking opportunities, and workspace. Startups that participated in incubator programs showed significantly higher rates of growth, innovation, and market readiness compared to those outside the incubators. Business incubators are essential for the success and growth of creative startups. Their support mechanisms help bridge the gap between idea development and market execution, contributing to the overall success and sustainability of creative industries.  
The Evolution of Portraiture in Contemporary Visual Arts Prayoga Saputra; Ethan Tan; Ava Lee
Journal of Humanities Research Sustainability Vol. 1 No. 5 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jhrs.v1i5.1794

Abstract

Background. This research aims to explore the evolution of portrait art in contemporary visual art, focusing on how portrait evolved from physical representation to a medium of social communication rich in critical messages and social themes. Purpose. The background of this research is based on the increasing use of digital media and the changing audience preference for portraits that convey relevant issues such as identity and social inequality.    Method. This research uses a qualitative method with a descriptive-analytical approach, through in-depth interviews with artists and participatory observation in art galleries. Results. The results show that contemporary portraits are more than just visual works; It becomes an effective advocacy tool, blending aesthetics with complex social issues. Portraits now not only display appearances, but also convey a powerful narrative that invites the audience to engage in the process of interpretation and reflection. Conclusion. The conclusion of the study underscores that contemporary portrait art plays an important role in strengthening social awareness and offers a new perspective on visual art as a medium capable of driving social change.  
The Humanities of Food Sustainability: A Cultural History of Local Food Movements and Agro-biodiversity in Indonesia Imam Hanafi; Jaden Tan; Ava Lee
Journal of Humanities Research Sustainability Vol. 2 No. 6 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jhrs.v2i6.2788

Abstract

Background. Indonesia’s contemporary food sustainability challenges reflect deep historical, cultural, and ecological transformations that have reshaped local food systems and agro-biodiversity. Local food movements have re-emerged as a response to the growing homogenization of diets, the erosion of indigenous agricultural knowledge, and the impact of industrial food regimes. These movements represent not only environmental initiatives but also cultural practices rooted in longstanding traditions of communal agriculture and ecological stewardship. Purpose. The research aims to analyze the cultural foundations of Indonesia’s local food movements, trace their historical development, and examine their contributions to sustaining agro-biodiversity.   Method. A qualitative historical-cultural method was employed, drawing on archival materials, ethnographic accounts, visual documentation, and policy analysis. Analytical procedures included thematic coding, cultural narrative reconstruction, and cross-period comparison to map continuities and ruptures in food sustainability practices. Results. Findings show that local food movements are deeply embedded in cultural memory and collective identity, functioning as mechanisms for ecological resilience, resistance to food commodification, and revitalization of traditional crop varieties. The movements demonstrate how cultural narratives, ritual practices, and local knowledge systems actively shape community-led strategies for conserving agro-biodiversity. Conclusion. The study concludes that food sustainability in Indonesia cannot be understood solely through ecological or economic lenses; it must be grounded in cultural history and humanistic inquiry. Strengthening local food movements therefore requires integrating cultural values, historical understanding, and community agency into national food sustainability policies.
THE SOCIOLOGY OF ISLAMIC RITUALS: EXAMINING THE ROLE OF RELIGION IN SHAPING SOCIAL BEHAVIOR Khoiriyah Khoiriyah; Ethan Tan; Ava Lee
Journal of Noesantara Islamic Studies Vol. 3 No. 1 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jnis.v3i1.3403

Abstract

Religion has long been a fundamental force in shaping social behavior, with Islamic rituals playing a central role in structuring moral and social conduct within Muslim communities. This study investigates the sociological dimensions of key Islamic rituals, including Salah (prayer), Sawm (fasting), Zakat (charity), and Hajj (pilgrimage), exploring how these practices influence individual and collective behavior. The aim of the research is to examine how Islamic rituals function as mechanisms for social cohesion, moral regulation, and identity formation. A qualitative research design was employed, utilizing semi-structured interviews and participant observation among Muslim individuals from diverse backgrounds. The findings indicate that these rituals not only foster personal spiritual growth but also strengthen social bonds, promote social responsibility, and encourage ethical conduct. Participants reported that Salah reinforced community unity, while Sawm and Zakat increased empathy and social responsibility. Hajj was viewed as a transformative experience, creating a sense of global Muslim identity. The study concludes that Islamic rituals are vital tools for fostering social solidarity and regulating social behavior, highlighting their dual role in personal devotion and community building. Understanding the sociological implications of these rituals provides valuable insights into the relationship between religion and society.
A SYSTEMIC AI AND CYBER-PHYSICAL FRAMEWORK FOR REAL TIME REMOTE PATIENT MONITORING IN INDONESIAN RURAL HEALTH CLINICS (PUSKESMAS) Ethan Tan; Ava Lee; Li Wei; Rustiyana Rustiyana
Scientechno: Journal of Science and Technology Vol. 4 No. 2 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/scientechno.v4i2.2894

Abstract

Access to healthcare in rural Indonesia remains a significant challenge due to limited medical resources and healthcare personnel, leading to delayed diagnosis and suboptimal patient care. Remote patient monitoring offers a potential solution by enabling real-time health assessments and reducing the need for long-distance travel to healthcare facilities. This study aims to design and implement a systemic Artificial Intelligence and Cyber-Physical Systems framework for real-time remote patient monitoring in rural primary health clinics in Indonesia to enhance patient care, support early disease detection, and optimize healthcare resource allocation. The research employed a hybrid AI–CPS approach that integrated wearable health devices, Internet of Things sensors, and cloud computing infrastructure to continuously monitor patient vital signs. Artificial Intelligence algorithms were utilized to analyze health data and identify early signs of potential health anomalies. Data were collected from multiple rural Puskesmas where remote monitoring devices were installed, and system performance was evaluated using metrics including data accuracy, response time, and user satisfaction. The results indicated that the system achieved a high level of accuracy, with a 92 percent success rate in predicting potential health anomalies, while feedback from healthcare workers and patients demonstrated positive perceptions, particularly in terms of convenience, efficiency, and time savings. Overall, the findings confirm that the AI and Cyber-Physical Systems-based remote patient monitoring framework is effective in improving healthcare delivery in rural Indonesian clinics and holds strong potential as a scalable solution to enhance accessibility and quality of rural healthcare services.
The Influence of Auditor's Professional Skepticism on Audit Quality Christine Dewi Nainggolan; Ethan Tan; Ava Lee
Journal Markcount Finance Vol. 3 No. 1 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jmf.v3i1.2133

Abstract

The rapid advancement of audit technology, including data analytics, artificial intelligence (AI), and blockchain, has significantly transformed the auditing profession. These technologies promise to enhance audit efficiency and effectiveness by automating routine tasks, improving data accuracy, and enabling deeper insights. However, the extent to which these technologies influence audit outcomes from the auditor's perspective remains underexplored, particularly in terms of their practical implementation and perceived benefits. This study aims to examine the influence of audit technology on audit efficiency and effectiveness from the perspective of auditors, focusing on their experiences, challenges, and perceived outcomes. A mixed-methods approach was employed, combining surveys and semi-structured interviews with auditors from public accounting firms. Quantitative data were analyzed using statistical techniques, while qualitative data were thematically analyzed to identify key patterns and insights. The findings reveal that audit technology significantly improves efficiency by reducing time spent on manual tasks and enhancing data processing capabilities. Auditors also reported increased effectiveness, as technology enabled better risk assessment, fraud detection, and compliance monitoring. However, challenges such as high implementation costs, skill gaps, and resistance to change were identified as barriers to full adoption. The study concludes that audit technology has a transformative impact on audit efficiency and effectiveness, but its successful integration requires addressing technical, organizational, and human factors.
IMPACT INVESTING AND CLIMATE FINANCE: MEASURING SOCIAL RETURN ON INVESTMENT (SROI) IN RENEWABLE ENERGY PROJECTS Ava Lee; Rachel Chan; Sanya Desai
Journal Markcount Finance Vol. 4 No. 2 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jmf.v4i2.2926

Abstract

This study examines the role of impact investing and climate finance in generating measurable social value through renewable energy projects by applying the Social Return on Investment (SROI) framework. Growing global investment in renewable energy has emphasized financial performance and emission reduction outcomes, while systematic measurement of social impacts remains limited. The purpose of this research is to assess how SROI can be used to quantify the social and environmental value created by renewable energy investments and to demonstrate its relevance for impact-oriented decision-making. A mixed-methods approach was employed, combining secondary project data analysis, stakeholder engagement, outcome mapping, and monetization of social and environmental benefits to calculate SROI ratios. The findings reveal that renewable energy projects consistently produce social returns exceeding the initial investment, with SROI ratios varying according to project type, scale, stakeholder involvement, and socio-economic context. Community-based and decentralized projects tend to generate higher relative social returns, driven by employment creation, improved energy access, health improvements, and environmental benefits. The study concludes that integrating SROI into climate finance evaluation enhances transparency, accountability, and alignment between financial objectives and sustainable development goals.  
SOCIAL ISOLATION AND COGNITIVE DECLINE IN AGING POPULATIONS: AI-POWERED MONITORING SYSTEMS FOR EARLY DETECTION Ava Lee; Thiago Costa; Clara Mendes
Journal of World Future Medicine, Health and Nursing Vol. 4 No. 1 (2026)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/health.v4i1.2373

Abstract

Social isolation is a significant and modifiable risk factor for accelerated cognitive decline and dementia in aging populations. Traditional methods for detecting cognitive changes, such as clinical screenings, are often infrequent and fail to capture the subtle, early behavioral shifts that precede a formal diagnosis. This study aimed to develop and validate an artificial intelligence model designed for the early detection of cognitive decline by passively monitoring behavioral and vocal biomarkers of social isolation in older adults living independently. A 24-month, prospective longitudinal study was conducted with a cohort of 200 community-dwelling adults aged 70 and older. A suite of unobtrusive in-home sensors was used to passively collect data on movement patterns, social communication (frequency and duration of conversations), and computer/phone usage. The AI-powered system identified individuals who would later show clinically significant cognitive decline with an accuracy of 91% and a lead time of approximately 7 months before formal assessment. Decreased frequency of vocal interactions and increased irregularity in daily routines were the most powerful predictors. AI-powered passive monitoring systems are a highly effective and ecologically valid tool for the pre-clinical detection of cognitive decline linked to social isolation.
Ethics of AI Tutors: Balancing Automation and Human Interaction in Education Ali Mufron; Ethan Tan; Ava Lee
Journal Emerging Technologies in Education Vol. 3 No. 5 (2025)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/jete.v3i5.2895

Abstract

Background. Artificial intelligence tutors are increasingly adopted in education to enhance efficiency, personalization, and accessibility. Despite their widespread use, ethical concerns related to reduced human interaction, moral responsibility, and learner well-being remain insufficiently addressed. Purpose. This study aims to examine the ethical implications of AI tutors by analyzing how automation can be balanced with meaningful human interaction in educational settings. Method. The study employs a qualitative descriptive approach using secondary statistical data, document analysis, and case study examination. Data are analyzed thematically to identify ethical patterns related to automation, human roles, and institutional governance. Results. The findings indicate that AI tutors effectively support structured learning activities but are limited in relational and emotional engagement. Educators perceive AI tutors as supplementary tools, while ethical responsibility is often managed informally due to the absence of explicit institutional guidelines. Conclusion. The study concludes that ethical integration of AI tutors requires intentional balance, where automation enhances efficiency and human interaction preserves educational values. The novelty of this research lies in its integration of ethical theory and educational practice to conceptualize AI tutors as complementary rather than substitutive agents within human-centered learning environments.