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All Journal Majalah Obstetri dan Ginekologi Majalah Kedokteran Sriwijaya Indonesian Journal of Obstetrics & Gynecology Science Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) SRIWIJAYA JOURNAL OF MEDICINE Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Pengabdian Masyarakat: Humanity and Medicine Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Perinatology
Martadiansyah, Abarham
Division Of Maternal Fetal Medicine, Department Of Obstetrics And Gynecology, Faculty Of Medicine, Universitas Sriwijaya / Mohammad Hoesin General Hospital, Palembang, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Pulmonary hypertension in pregnancy Bernolian, Nuswil; Kesty, Cindy; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham; Agustria, Rizky
Indonesian Journal of Perinatology Vol. 5 No. 1 (2024): Available online: 1 June 2024
Publisher : The Indonesian Society of Perinatology, South Jakarta, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/inajperinatol.v5i1.36

Abstract

Pulmonary hypertension (PH) is a persistent increase in mean pulmonary arterial pressure (mPAP) of at least 20–25 mm Hg during right cardiac catheterization. For every million patients, there were 97 PH cases. Women are more likely than men (1.7:1) to receive a diagnosis, with a mean age of 37 years. The classification, pathophysiology, mechanism, and management of postpartum hemorrhage (PH) are the main aims of this review study. Pulmonary artery hypertension (PAH), pulmonary hypertension (PH) associated with left heart disease, pulmonary hypoxia and/or lung illnesses, chronic thromboembolic PH, and PH with unknown multifactorial processes are the five categories into which PH is divided. Women, particularly those of reproductive age, make up about 80% of individuals with idiopathic PAH. Pregnancy-related PH is one of the long-standing heart conditions with a significant morbidity and mortality rate. Its estimated death rate ranges from 30.56%. Pregnancy is therefore not advised in PH patients. Treating people with PH requires early diagnosis and effective treatment. These patients have optimism because of the impending PH medications (phosphodiesterase type 5 inhibitors, nitric oxide, endothelin receptor antagonists, and calcium channel blockers) as well as the advancements in hemodynamic monitoring and intensive care in PH specialty facilities. Pregnant women with PH should be treated with a multidisciplinary approach, such as obstetricians, cardiologists, intensivists, and neonatologists.
Pencegahan Abortus pada Awal Kehamilan Bernolian, Nuswil; Pangemanan, Wim T.; Syamsuri, Ahmad Kurdi; Ansyori, M. Hatta; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham; Kesty, Cindy
Indonesian Journal of Obstetrics & Gynecology Science Volume 6 Nomor 3 November 2023
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v6i3.403

Abstract

Abortus merupakan suatu kejadian terminasi kehamilan dengan usia kehamilan <20 minggu dan berat janin <500 g. Angka kejadian abortus disebutkan sekitar 15% dari seluruh kehamilan. Terdapat beberapa faktor risiko abortus yaitu faktor risiko yang dapat dimodifikasi dan tidak dapat dimodifikasi. Beberapa faktor risiko yang dapat dimodifikasi yaitu faktor nutrisi, konsumsi kafein, alkohol, kebiasaan merokok, infeksi, paparan radiasi, beban kerja, dan pengaruh obat-obatan. Beberapa faktor risiko yang tidak dapat dimodifikasi, yaitu genetik, kelainan kongenital, dan lain-lain. Dengan mengetahui faktor risiko tersebut, dokter dapat melakukan pencegahan dan intervensi yang sesuai dengan kondisi masing-masing pasien yang mengalami abortus. Metode yang digunakan adalah tinjauan pustaka dengan menggunakan beberapa database seperti Pubmed, Wiley Online Library, dan ScienceDirect dari 10 tahun terakhir.Prevention of Miscarriage in Early PregnancyAbstractMiscarriage is an event of termination of pregnancy with < 20 weeks of gestation and fetal weight < 500 grams. The incidence of miscarriage is around 15% of all pregnancies. There are several risk factors for miscarriage, namely modifiable and non-modifiable risk factors. Some modifiable risk factors are nutritional factors, consumption of caffeine, alcohol, smoking habit, infection, radiation exposure, workload, and the influence of drugs. Several risk factors that can not be modified, namely genetics, congenital abnormalities, and others. By knowing these risk factors, doctors can carry out prevention and intervention according to the conditions of each patient who undergoes miscarriage. The method used is a literature review using several databases such as Pubmed, Wiley Online Library, and ScienceDirect from the last 10 years.Key words: miscarriage, prevention, risk factors, pregnancy.
Multigravida 37 Weeks Pregnant Not in Labour with Carotid Cavernous Fistula Life Single Fetus Head Presentation: Case Report Puspitasari, Dwi Cahya; Bernolian, Nuswil; Pangemanan, Wim Theodorus; Syamsuri, Ahmad Kurdi; Ansyori, Muhammad Hatta; Mirani, Putri; Lestari, Peby Maulina; Martadiansyah, Abarham
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.611

Abstract

Background: Carotid cavernous fistula (CCF) is an abnormal shunt from the carotid artery to the cavernous sinus. The management of pregnant patients with CCF is individualized. The aims of this case report are to document a rare presentation of a multigravida at 37 weeks of gestation with a carotid cavernous fistula, describe clinical symptoms and management, report outcomes, and contribute insights to the medical literature.Case Report: The referred patient, G2P1A0, who was 37 weeks pregnant with a live single fetus in cephalic presentation, presented with left eye swelling persisting since the first pregnancy at 6 months gestation, associated with headaches. The patient underwent neurosurgical intervention at Mohammad Hoesin Hospital, including digital subtraction angiography (DSA). Currently, experiencing preterm labor symptoms, the management includes inpatient care, blood transfusion (Hb > 10 g/dL), and termination via the perabdominal approach.Discussion: A multigravida at 37 weeks pregnant in labor with carotid cavernous fistula and a live single fetus in head presentation, as existing literature suggests, has no clear link between maternal carotid cavernous fistula history and fetal outcomes. Despite concerns about potential fetal abnormalities and cancer risk from endovascular embolization therapy during pregnancy, postpartum follow-up with advanced digital subtraction angiography (DSA) is planned.Conclusion: The complexity of managing a multigravida at 37 weeks pregnant in labor with carotid cavernous fistula and a live single fetus in head presentation emphasizes the importance of a multidisciplinary approach for optimal maternal and fetal outcomes.Multigravida Hamil 37 Minggu Belum Inpartu dengan Fistula Cavernosa Karotis Janin Tunggal Hidup Presentasi Kepala: Laporan KasusAbstrakLatar belakang: Fistula kavernosus karotis (CCF) adalah celah/ lubang abnormal dari arteri karotis ke sinus kavernosus. Penatalaksanaan pasien hamil dengan CCF bersifat individual. Tujuan dari laporan kasus ini adalah untuk mendokumentasikan presentasi langka seorang multigravida pada usia kehamilan 37 minggu dengan fistula kavernosus karotis, mendeskripsikan gejala klinis dan penatalaksanaannya, melaporkan hasil, dan menyumbangkan wawasan untuk literatur medis.Laporan Kasus: Pasien yang dirujuk, G2P1A0, pada usia kehamilan 37 minggu dengan janin tunggal hidup dengan presentasi kepala, datang dengan pembengkakan mata kiri yang berlangsung sejak kehamilan pertama pada usia kehamilan 6 bulan, yang berhubungan dengan sakit kepala. Pasien menjalani intervensi bedah saraf di Rumah Sakit Mohammad Hoesin, termasuk Digital Subtraction Angiography (DSA). Saat ini, mengalami gejala persalinan prematur, penatalaksanaan yang dilakukan meliputi rawat inap, transfusi darah (Hb > 10 g/dL), dan terminasi melalui pendekatan perabdominal.Diskusi: Seorang multigravida dengan usia kehamilan 37 minggu yang melahirkan dengan fistula kavernosa karotis dan janin tunggal hidup dengan presentasi kepala, merupakan kasus yang jarang terjadi, karena literatur yang ada menunjukkan tidak ada hubungan yang jelas antara riwayat fistula kavernosa karotis ibu dan hasil janin. Meskipun ada kekhawatiran mengenai potensi kelainan janin dan risiko kanker dari terapi embolisasi endovaskular selama kehamilan, tindak lanjut pascapersalinan dengan angiografi pengurangan digital (DSA) lanjutan direncanakan.Simpulan: Kompleksitas pengelolaan multigravida dengan usia kehamilan 37 minggu dalam persalinan dengan fistula kavernosa karotis dan janin tunggal hidup dengan presentasi kepala, menekankan pentingnya pendekatan multidisiplin untuk luaran ibu yang optimal. Perlunya pendektanan multidispilin keilmuan memeberiksan hasil yanga baik pada ibu dan bayinya.Kata kunci: Fistula Kavernosa Karotis, Angiografi Pengurangan Digital
Congenital Diaphragmatic Hernia Anomaly in Multigravida at 36 Weeks Gestation with One Previous Cesarean Section, Single Live Fetus, Cephalic Presentation: Case Report Putri, Asri Indriyani; Martadiansyah, Abarham; Bernolian, Nuswil; Al Farisi Sutrisno, Muhammad; Nisfita, Rizania Raudhah; Maharsi, Rahma
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 2 Juli 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i2.613

Abstract

Background: Case of a multigravida at 36 weeks of gestation with one previous cesarean section carrying a single fetus was diagnosed with diaphragmatic hernia. This case aims to address the challenges posed by this complex scenario of diaphragmatic hernia and the importance of specialized care to ensure optimal maternal and fetal outcomes.Case Report: Referred from Muhammadiyah Hospital Palembang, the patient at 36 weeks of gestation with G3P2A0 status present a single live fetus and was diagnosed with diaphragmatic hernia. Following prior midwife care where fetal heartbeats were not detected, the patient was referred to Dr. Mohammad Hoesin Central General Hospital Palembang. The management plan includes a one-week follow-up and folic acid, calcium carbonate, and iron supplementation.Discussion: Congenital diaphragmatic hernia (CDH) is a developmental defect causing diaphragmatic discontinuity, diagnosed prenatally with 40% to 90% accuracy via ultrasound. The treatment aims to minimize lung hypoplasia and reduce mortality, typically performed at 26-28 weeks for severe cases and 30-32 weeks for moderate ones. The optimal delivery timing for CDH remains controversial, with lung-to-head ratio as a widely used prognostic indicator.Conclusion: Congenital diaphragmatic hernia (CDH) exhibits lower survival rates on the right side (50% vs. 75%), with lung area to head circumference ratio (LHR) as a common prognostic parameter. Recent minimally invasive techniques like FETO aim to improve prognosis by reducing pulmonary hypoplasia and mortality.Laporan Kasus: Multigravida Hamil 36 Minggu Belum Inpartu Bekas Seksio Sesarea Satu Kali Janin Tunggal Hidup Presentasi Kepala Dengan Anomali Kongenital Hernia DiafragmatikAbstrakLatar Belakang: Kasus multigravida hamil 36 minggu dengan riwayat operasi caesar janin tunggal hidup yang didiagnosis hernia diafragma. Tujuan laporan kasus ini untuk mengatasi tantangan yang ditimbulkan oleh skenario kompleks hernia diafragma dan menunjukkan pentingnya perawatan khusus untuk memastikan hasil akhir ibu dan janin yang optimal.Laporan Kasus: Pasien usia kehamilan 36 minggu dengan status G3P2A0 janin hidup tunggal dengan diagnosis hernia diafragma dirujuk dari RS Muhammadiyah Palembang setelah sebelumnya diperiksa oleh bidan dan tidak terdeteksi detak jantung janinnya sehingga memerlukan rujukan ke RSUP Dr. Mohammad Hoesin Palembang. Rencana penatalaksanaannya mencakup tindak lanjut selama satu minggu, bersamaan dengan suplementasi asam folat, kalsium karbonat, dan zat besi.Diskusi: Hernia diafragma kongenital (CDH) merupakan kelainan perkembangan yang menyebabkan diskontinuitas diafragma dan didiagnosis sebelum lahir dengan akurasi 40% hingga 90% melalui ultrasonografi. Tatalaksana bertujuan untuk meminimalkan hipoplasia paru-paru dan mengurangi angka kematian, biasanya dilakukan pada minggu ke 26 sampai 28 untuk kasus yang parah dan 30 - 32 minggu untuk kasus yang sedang. Waktu persalinan yang optimal untuk CDH masih kontroversial, dengan rasio paru-paru sebagai indikator prognosis yang banyak digunakan.Kesimpulan: Hernia diafragmatika kongenital (CDH) menunjukkan tingkat kelangsungan hidup yang lebih rendah pada sisi kanan (50% vs. 75%), dengan rasio area paru terhadap lingkar kepala (LHR) sebagai parameter prognosis yang umum; teknik invasif minimal terkini bertujuan untuk meningkatkan prognosis dengan mengurangi hipoplasia paru dan kematian.Kata kunci: Hernia Diafragma Kongenital, Riwayat Operasi Caesar Sebelumnya, Multigravida 
Prevalence and Distribution of Risk Factors for Preterm Labor in RSUP DR. Mohammad Hoesin Palembang Period January 1 2020 – December 31 2023 Beumaputra, Adyatma Utama; Martadiansyah, Abarham; Nurwany, Raissa; Mirani, Putri; Putra, Hadrians Kesuma
Indonesian Journal of Obstetrics & Gynecology Science Volume 8 Nomor 1 Maret 2025
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v8i1.825

Abstract

Objective: This study aims to determine the prevalence and distribution of risk factors for preterm labor.Methods: This is a descriptive observational study with a cross-sectional design. The data used in this study were secondary data obtained with the total sampling method from the medical records of Dr. Mohammad Hoesin Palembang Hospital from January 1, 2020 to December 31, 2023.Results: This study found 1,654 cases of preterm labor from January 1, 2020 to December 31, 2023. The analysis of risk factors among mothers indicated that those within the high-risk age categories (<20 years and >35 years) constituted 31.7%. Multiparous and grand multiparous women represented 41.7%, while multiple pregnancies accounted for 6.6%. A history of premature rupture of membranes was noted in 25.4% of cases, polyhydramnios was observed in 1.3%, and a history of cesarean delivery was found in 25.4%. Furthermore, 33% suffered from hypertension, and 2.5% had diabetes. Anemia was prevalent in 47.9% of the mothers, and infection was reported in 42.8%. A history of preterm delivery was noted in 13.7%, risky gestational distance was found in 10.6%, and 25% had a history of antepartum hemorrhage. Finally, obesity was observed in 14.5% of the mothers.Conclusion: The number of deliveries continued to decrease, but the prevalence of preterm labor increased from 2020 to 2023. Anemia is the most common risk factor found in mothers with preterm labor.Prevalensi dan Distribusi Faktor Risiko Persalinan Prematur di RSUP Dr. Mohammad Hoesin Palembang dalam Tiga TahunAbstrakTujuan: Penelitian ini bertujuan untuk mengetahui prevalensi serta distribusi faktor risiko persalinan prematur.Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross-sectional. Data yang digunakan dalam penelitian ini merupakan data sekunder dengan metode total sampling dari data rekam medik RSUP Dr. Mohammad Hoesin Palembang periode 1 Januari 2020 – 31 Desember 2023.Hasil: Terdapat 1654 kasus persalinan prematur dengan periode 1 Januari 2020 – 31 Desember 2023. Distribusi faktor risiko didapatkan ibu dengan usia berisiko (<20 tahun dan >35) tahun (31,7%), paritas multipara dan grandemultipara (41,7%), kehamilan multipel (6,6%), riwayat ketuban pecah dini (25,4%), polihidramnion (1,3%), riwayat persalinan sesar (25,4%), hipertensi (33%), diabetes (2,5%), anemia (47,9%), infeksi (42,8%), riwayat persalinan prematur (13,7%), jarak kehamilan berisiko (10,6%), riwayat perdarahan antepartum (25%), obesitas (14,5%). Kesimpulan: Jumlah persalinan terus mengalami penurunan, namun prevalensi kejadian persalinan prematur terus mengalami peningkatan dari tahun 2020-2023. Anemia menjadi faktor risiko paling banyak yang ditemukan pada ibu dengan persalinan prematur.Kata kunci: Prevalensi, Persalinan Prematur, Faktor Risiko
COVID-19 in pregnancy: Maternal and perinatal outcomes at Dr. Mohammad Hoesin Hospital, Palembang, Indonesia Martadiansyah, Abarham; Mirani, Putri; Ridwan, Metta Rania; Hartati; Andriyani Liberty, Iche; Stevanny, Bella
Majalah Obstetri & Ginekologi Vol. 33 No. 1 (2025): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V33I12025.11-20

Abstract

HIGHLIGHTS COVID-19 increases the likelihood of adverse maternal outcomes throughout pregnancy, including pneumonia, cesarean section, and ICU admission. Prompt diagnosis and treatment of COVID-19 may improve maternal outcomes. COVID-19 does not increase the likelihood of adverse perinatal outcomes. Reassurance can be provided to expectant mothers.   ABSTRACT Objective: The objective of this study was to analyze the maternal and perinatal outcomes of COVID-19 in pregnancy at Dr. Mohammad Hoesin Hospital, Palembang, Indonesia. Materials and Methods: This retrospective cohort study was carried using medical records of pregnant mothers who delivered at Dr. Mohammad Hoesin Hospital Palembang from March 2020 to August 2021. The subjects were into two groups: pregnant women with and without COVID-19. Pearson Chi-Square test was used for bivariate analysis to determine the associations between COVID-19 and maternal as well as neonatal outcomes. The data were analysed using the Stata 15 statistical software. Multivariate analysis was done using the cox regression test to determine whether maternal characteristics affected those associations. P-value of < 0.05 were considered statistically significant. Results: The study analyzed 220 subjects, including 62 COVID-19-positive (28.18%) and 158 COVID-19-negative (71.82%) patients. Among expectant mothers with COVID-19, caesarean sections were the most common maternal outcome (82.26%), while fetal distress was the most frequent perinatal outcome (12.13%). Significant associations were found between COVID-19 and maternal outcomes, including pneumonia (RR = 12.76), caesarean section (RR = 2.74), and ICU hospitalization (RR = 6.90). These associations remained significant after adjusting for maternal characteristics. However, no significant association was found between COVID-19 and perinatal outcomes. Conclusion: COVID-19 increases the likelihood of adverse maternal outcomes throughout pregnancy.
Preterm Multigravida with Two Previous Cesarean Deliveries and a Fetus with Asymmetric IUGR and Cleft Lip and Palate: A Case Report Jhonatan, Senna Moca; Martadiansyah, Abarham; Bernolian, Nuswil; Mirani, Putri; Lestari, Peby Maulina; Agustria, Rizky; Arjanggi, Kiagus Irawan Satria
Sriwijaya Journal of Medicine Vol. 8 No. 2 (2025): Vol 8, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v8i2.336

Abstract

Cleft lip and palate and intrauterine growth restriction (IUGR) are common congenital conditions and may suggest subtle genetic abnormalities. When no chromosomal defects are detected through standard testing, this combination presents a diagnostic challenge in prenatal care. . This case report presents a 33-year-old multigravida woman at 34 weeks of gestation, referred for suspected fetal growth restriction and cleft palate. Serial ultrasound examinations confirmed asymmetric IUGR along with a complete cleft involving the lip, alveolus, and palate. Elective cesarean delivery of pregnancy was performed at 36 weeks of gestation via cesarean section, with the infant diagnosed with unilateral cleft lip and palate. This case underlines the importance of considering advanced genetic testing in non-syndromic cases of CLP with IUGR. This case highlighting a gap in standard prenatal diagnostics and emphasizing the need for a broader genetic approach in such cases. Clinicians should remain alert and pursue early, comprehensive evaluation and multidisciplinary planning to ensure accurate diagnosis, timely intervention, and better neonatal outcomes.
Co-Authors A. Kurdi Syamsuri Adnan Abadi Agustria, Rizky Al Farisi Sutrisno, Muhammad Alia Desmalia Anang Ansyori Andriyani Liberty, Iche Ansyori, Muhammad Hatta Ardesy Melizah Kurniati Arjanggi, Kiagus Irawan Satria Azhari, Dalilah Bernolian, N Bernolian, N Beumaputra, Adyatma Utama Budi Santoso Chairil Anwar Cindy Kesty Citra Dewi Dwi Budi Santoso Dwi Handayani Erwin Sukandi Fatimah , Nyimas Febi Stevi Aryani Feisal Moulana Firmansyah Basir Gita Dwi Prasasty HARTATI Heni Yusnita, Heni Iche Andriani Liberty Izzulhaq, Muhammad Agung Jhonatan, Senna Moca Kesty, Cindy Kesuma, Putri Zalika Kusuma, Hadrians M. Hatta Ansyori Maharsi, Rahma Maulani, H Maulani, H Murwani Emasrissa Latifah Muwarni Emasrissa Latifah Nahrani, Ulya Ni Made Dyah Gayatri Nisfita, Rizania Raudhah Nurwany, Raissa Nuswil Bernolian Pangemanan, W T Pangemanan, W T Pangemanan, Wim Theodorus Peby M. Lestari Peby Maulina Peby Maulina Lestari, Peby Maulina Purnamasari, Septi Purnomo, Abdul Harits Puspitasari, Dwi Cahya Putra, Hadrians Kesuma Putri Maya Sari Putri Mirani Putri Mirani Putri Mirani Putri Mirani Putri Mirani Putri, Asri Indriyani Qalbi, Anugrah Qalbi, Anugrah Rasyid, Riana Sari Puspita Rasyid, Riana Sari Puspita Riana Sari Puspita Rasyid Ridwan, Metta Rania Rizky Agustria Shiddiq, Abdul Halim Stevanny, Bella Sugianto Mukmin Syamsuri, Ahmad Kurdi Syarif Husin Syifa, Syifa Theodorus Theodorus Theodorus Theodorus Theodorus Tia Kaprianti tian kaprianti Trisa, Yusdela Trisa, Yusdela Wim T. Pangemanan Wim T. Pangemanan Win T. Pangemanan Yulistiana, Sisca Yusdela Trisa