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All Journal Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Pharmacon Jurnal Teknologi dan Sistem Komputer Media Farmasi Journal of Dedicators Community JPSCR : Journal of Pharmaceutical Science and Clinical Research Forest and Society Jurnal Mandala Pharmacon Indonesia Abdimas UNWAHAS : Jurnal Pengabdian Masyarakat UNWAHAS Jurnal Ilmiah Cendekia Eksakta Jurnal Mandala Pengabdian Masyarakat Jurnal Pengabdian Masyarakat Abdimas Madani PROFICIO: Jurnal Pengabdian Masyarakat Media Farmasi Indonesia Jurnal Farmasi Sains dan Praktis Borneo Journal of Pharmacy
Ayu Shabrina
Universitas Wahid Hasyim
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

 1 
Physical Stability of Sea Buckthorn Oil Nanoemulsion with Tween 80 Variations Ayu Shabrina; Icha Sabrina Milenia Khansa
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.42809

Abstract

Sea buckthorn oil (SBO) contains fatty acids that have an anti-aging effect. The delivery system ofSBO can be improved by a nanoemulsion system. The purpose of this study was to determine thephysical stability of SBO nanoemulsion (NSB) with Tween 80 variation. NSB was made with 1% SBOand Tween 80 variation of 35% (FI); 40% (FII) and 45% (FIII). NSB was stored in a climatic chamberat 30 ± 2°C and RH of 65%±5% for 90 days. Samples were taken before storage on the 15th, 30th,60th, and 90th days. Evaluations were carried out including appearance, particle size, polydispersityindex (PI), transmittance percentage (TP), pH, and viscosity. Quantitative data were analyzed withmultivariate analysis. The result showed that NSB formulas were yellowish-orange and clear. Thedroplet size in FII and FIII was stable (p > 0.05) with a range of 12-15 nm with PI < 0,5. All formulashad TP > 95% with a pH of 7.50–7.6. The viscosity of all formulas was 1.2-1.9 dPa.s and characterizedas Newtonian. Increasing the concentration of tween 80 can reduce droplet size and PI. Tween 80 at aconcentration of 35-45% produces sea buckthorn nanoemulsion which is stable for 90 days of storage.
Physical Stability and Effectivity Comparison of Nanoemulsion and Nano-emulgel of Avocado Oil with Carbopol 940 Variation Shabrina, Ayu
Indonesian Journal of Pharmaceutical Science and Technology 2024: Suppl. 6, No. 1 (Special Issue for Mulawarman Pharmaceutical Conference)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v6i1.53215

Abstract

Avocado oil (AV) contains of oleic acid that can prevent skin erythema. Nanoemulsion (NE) in a gel system (NG) is a one of a delivery system that increases the drug's effectivity. This study aimed to compare AV's stability and effectivity as anti-erythema in NE and NG with variations of carbopol 940. NE was made with 5% of AV and incorporated in carbopol 940 (for NG) with variations of 0.5 (F1);1 (F2), and 1.5% (F3). The samples were stored in a climatic chamber for 90 days at a temperature of 30 °C ± 2 °C RH 65% ± 5%. Samples were tested for organoleptic, pH, viscosity, particle size (PS), polydispersity index (PDI), and zeta potential (ZP). The samples were also tested based on in vitro SPF values and minimum erythema dose (MED). The results show that NE has a clear appearance whie NG showed a creamy texture. The physical parameters met the criteria for nanoemulsion delivery. F1 NG showed an increase in physical parameters, while F2 and F3 were stable for 90 days of storage. The SPF value of AV in NE and NG were not significantly different, yet the MED showed differences in each formula. Carbopol at a concentration of 0.5-1.5% can produce stable nano-emulgel. Avocado oil nanoemulsion showed better effectivity to prevent erythema than nano-emulgel.
Co-Authors Adhi Gunawan Agnes Theresya Poerba Annisa Rahayuning Pratiwi Arnida Lailatul Latifah Astri Risma Debi Auliasari, Dewi Wulandari Aza Zakiyatun Nida Aza Zakiyatun Nida Daipadli Daipadli Dharmawan Dharmawan Dhimas Adhityasmara Diana Anisa Setyani Eka Sakti Wahyuningtyas Elya Zulfa Erika Indah Safitri Faza Putri_Maulina Hanik Gunawan, Adhi Hafiz, Nur Heny Puspasari Heroweti, Junvidya Hidayati, Ishardina C. I Nyoman Sujana Ibrahim Arifin Ibrahim Arifin Ibrahim Arifin Ibrahim Arifin Icha Sabrina Milenia Khansa Ilma Nur Khafifa Inna Syafarina Intan Nuni Wahyuni Intan Pratiwi Junvidya Heroweti Junvidya Herowety Kabur, Savio Ricardus KHOIRUL ANWAR Khoirul Anwar Kintoko Kintoko Kintoko, Kintoko Latifah, Arnida L. M Fatchur Rochman M Fatchur Rochman MARIA ULFAH Mimiek Muurukmihadi Misbahul Munir Muddiin, Muhammad Imaa Muhammad Farih Arsyada Muhammad Ikhsan M_Rifki Pratama_Kharisma Akbar Nalaratih, Novinda Nevy Pratiwi Niswatus Sholihah Nurkhasanah Nurkhasanah Pratama, Fandy Indra Prihantini, Malinda Puspasari, Heny Puspita, Weni Rabiatul Adawiyah Ratna Hapsari Ratna Hapsari Tri Mustika Dewi Rima Nofitasari Ririn Lispita Wulandari Risha Fillah Fithria risha fillah fithria Riyanti, Winanti Adi Rizky Adityo Saputro Saniya Alfa Salsabila Sapto Yuliani Siti Setianingsih Sri Eka Rahmadany Sri Eka Rahmadany Sri Febri Haryati Sri Suwarni Sumantri Sumantri Surti Khayatul Fata Susiana Irmawati Urva Fresiva Uswatun Hasanah Vironica Rizky Fauziah Wahyu Setyo Wibowo Wahyuni, Intan N. Wijayatri, Ratna Yulias Ninik Windriati Zuhriya Muna Zuhriya Muna Firdausi