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Tingkat Pengetahuan terhadap Donor Darah pada Masyarakat Pendonor Afrianti, Dina; Susilawati, Elis; Sofyanita, Eko Naning
Jaringan Laboratorium Medis Vol. 4 No. 1 (2022): May 2022
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v4i1.8445

Abstract

Blood donation is an activity to donate blood for transfusion purposes. The number of voluntary blood donors in Indonesia is around 20% of the total production of blood bags per year, the rest is met from replacement donors. People are generally reluctant to donate blood because of fear of pain when blood is drawn using a syringe, fear of running out of blood, resulting in anemia, contracting the disease through blood donors, feeling unwell to donate blood and feeling that it is enough to only donate blood once. This is a factor that causes the limited number of donors due to limited knowledge. Research Objectives: To see an overview of the level of knowledge about blood donors in the community of donors at Pekalongan City. Methods: The type of research used is descriptive quantitative with a cross sectional approach with a questionnaire to determine the level of knowledge of the donor community. Results: Most of the blood donors at the Pekalongan City are Male 73 respondents (73%), the highest percentage aged 17-30 years as many as 54 respondents (54%), high school education, namely as many as 49 respondents (49%). Most of the donor knowledge level is said to be good, namely 88 respondents (88%). Conclusion: Most of the donor community at the Pekalongan City have a good level of knowledge about blood donation.
Realisme Sosial dalam Potret Seorang Komunis Karya Sabar Anantaguna Susilawati, Elis; Rahayu, Ismah; Salsabila, Akifah Humaira; Bahtiar, Ahmad
Stilistika: Jurnal Pendidikan Bahasa dan Sastra Vol 15 No 1 (2022)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/st.v15i1.8706

Abstract

Social Realism in Potret Seorang Komunis by Sabar Anantaguna ABSTRAKPuisi Potret Seorang Komunis karya Sabar Anantaguna telah mendapatkan bentuk dan pengucapan yang tepat sehingga menjadi prestasi yang bagus dalam sastra realisme sosialis karena tidak terlepas dari latar belakang dan ideologi pengarang yang merupakan bagian dari Lekra. Penelitian ini bertujuan untuk membahas prinsip realisme sosial yang menjadi pandangan para pengarang Lekra. Metode analisis yang digunakan dalam penelitian ini adalah metode penelitian deskriptif kualitatif dan teknik interpretatif. Dalam pengolahan data dilakukan tahap pendeskripsian dan penganalisisan. Penelitian ini menggunakan teori sosiologi sastra, teori realisme sosial dan teori struktural. Hasil dari penelitian Realisme Sosial dalam Potret Seorang Komunis Karya sabar Anantaguna terbukti bahwa prinsip realisme sosial yang menjadi pandangan para pengarang Lekra yaitu Lekra memiliki berbagai macam cara yang dilakukan dengan maksud mempertahankan kekuatan komunis, salah satunya melakukan berbagai teror kepada setiap golongan untuk bergabung dengan Lekra. Kata kunci: komunis, puisi, realisme sosial, lekra ABSTRACTThe poem portrait of a communist written by Sabar Anantaguna has obtained the right form and pronunciation. Therefore, it becomes a good achievement in social realism literature because it cannot be separated from the author background and ideology who is part of Lekra This study aims to discuss the social realism principles that becomes the views of the Lekra authors. The method used in this research is descriptif qualitative and note taking techniques. In processing data, the stages of description and data analysis are carried out. This study used sociology literature research, realism social teory and structural teory. The result of the research on social realism in the portrait of a communist by Sabar Anantaguna proves that realism social principle becomes the views of Lekra author, namely Lekra, had various ways that were carried out to maintain communist power, one of which carried out various terrors to every groups in order to join LekraKeyword: communist, poem, social realism, Lekra
Gel Formulations of Guava Leaves (Psidium Guajava L) Leaves Ethanol Extract As a Wound Healing Of Burns in Rabbits Sutrisno, Entris; Susilawati, Elis; Herdiana, Geralda Bintang; Noviyanti, Eva
International Journal of Research in Community Services Vol. 5 No. 2 (2024)
Publisher : Research Collaboration Community (Rescollacom)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46336/ijrcs.v5i2.626

Abstract

The ethanol extract of guava leaves (Psidium guajava L) in previous studies was known to have antiburn, antiinflammatory, antidiarrhea and antibacterial activity. The preparations made are gel preparations which are preferred by the public. The purpose of this study was to determine the activity of guava leaf ethanol extract gel and its effective concentration in healing burns in rabbits. The research method uses rabbits 4 tails made 5 wounds on the back, consisting of negative control, comparison (Bioplacenton®), gel preparations 3%, 5%, and 11%. Wound diameter measurements were carried out on days 3, 6, 9, 12, 15 and 18. The parameters observed were the size of the wound diameter, wound healing such as wound drying, scab formation, closure of the wound and the growth of new hair around the wound. An inflammatory process occurs for 3 days after injury and not processed wound healing. Fibroblasts appeared on day 6 and peaked on day 9, so that on day 9 all treatment and control groups experienced linear healing. On the 9th day the fibroblasts began to peel off on the skin indicating the group has reached the peak of the proliferation phase and wound contractions occur gradually urgent. The results of the guava leaf extract gel activity test (Psidium guajava L) showed a concentration of 11% gave the best effect.
PENGARUH PEMBIASAAN SHALAT DHUHA TERHADAP KECERDASAN SPIRITUAL PESERTA DIDIK Susilawati, Elis; Sulaeman, Oyib; KURNIAWAN, Ase
THORIQOTUNA: Jurnal Pendidikan Islam Vol. 5 No. 2 (2022): THORIQOTUNA: Jurnal Pendidikan Islam
Publisher : Prodi PAI IAILM Suryalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47971/tjpi.v5i2.565

Abstract

The study aims to determine the influence of habituation dhuha prayer on the spiritual intelligence of students at MA Muslimin Panjalu. The method used is a quantitative descriptive, data prcessing through Spearman rank correlation ( ). The result showed that the influence of habituation dhuha prayer on the spiritual intelligence of students at MA Muslimin Panjalu was quite significant, = 0.65 was in the interval 0.61 – 0.80 with high classification. And (3.80) ≥ (1.729). The habituation dhuha prayer can increase spiritual intelligence of students by 42.25%, so that 57.75% of spiritual intelligence of students is influenced by other factors outside of the research Penelitian ini bertujuan untuk mengetahui pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu. Metode yang digunakan adalah kuantitatif deskriptif, pengolahan data melalui rank spearman (). Hasil penelitian diperoleh pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu cukup signifikan dengan kategori tinggi berdasarkan = 0.65 berada pada interval 0.61 – 0.80 dengan klasifikasi tinggi. Serta (3.80) ≥ (1.729). Pembiasaan shalat dhuha mempengaruhi kecerdasan spiritual peserta didik sebesar 42.25%, sedangkan 57.75% kecerdasan spiritual peserta didik dipengaruhi oleh faktor lain diluar penelitian
Implementasi shalat dhuha dalam meningkatkan kecerdasan spiritual peserta didik Susilawati, Elis; Sulaeman, Oyib; Kurniawan, Ase
THORIQOTUNA: Jurnal Pendidikan Islam Vol. 6 No. 1 (2023): THORIQOTUNA: Jurnal Pendidikan Islam
Publisher : Prodi PAI IAILM Suryalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47971/tjpi.v6i1.687

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu. Metode yang digunakan adalah kuantitatif deskriptif, pengolahan data melalui rank spearman (r_s). Hasil penelitian diperoleh pengaruh pembiasaan shalat dhuha terhadap kecerdasan spiritual peserta didik di MA Muslimin Panjalu cukup signifikan dengan kategori tinggi berdasarkan r_s = 0.65 berada pada interval 0.61 – 0.80 dengan klasifikasi tinggi. Serta t_(hitung ) (3.80) ≥ t_tabel (1.729). Pembiasaan shalat dhuha mempengaruhi kecerdasan spiritual peserta didik sebesar 42.25%, sedangkan 57.75% kecerdasan spiritual peserta didik dipengaruhi oleh faktor lain diluar penelitian
Efek Kombinasi Ekstrak Etanol Rimpang Kunyit (Curcuma longa L.) dan Daun Pegagan (Centella asiatica (L.) Urb) terhadap Ekspresi Gen eNOS pada Jaringan Hati Tikus Obes Sulaeman, Agus; Agustian, Salim; Susilawati, Elis; Muhsinin, Soni; Kaniawati, Marita; Feliana, Marita
Journal of Pharmascience Vol 12, No 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.23813

Abstract

Obesitas adalah kondisi patologis akibat akumulasi lemak berlebih yang meningkatkan risiko gangguan metabolik, termasuk disfungsi endotel yang ditandai oleh penurunan produksi Nitric Oxide (NO) sintesis oleh enzim Endothelial Nitric Oxide Synthase (eNOS). Penelitian ini bertujuan mengevaluasi efek kombinasi ekstrak etanol rimpang kunyit (Curcuma longa L.) dan daun pegagan (Centella asiatica (L.) Urb) terhadap kadar NO serum dan ekspresi gen eNOS pada jaringan hati tikus obesitas. Penelitian eksperimental ini menggunakan tikus jantan yang diinduksi obesitas dengan pakan tinggi lemak dan karbohidrat selama 60 hari. Tikus dibagi enam kelompok: normal (kontrol negative), obesitas (kontrol positif), pembanding orlistat 10,8 mg/kgBB, ekstrak kunyit 200 mg/kgBB, ekstrak pegagan 20 mg/kgBB, dan kombinasi kunyit-pegagan 200:100 mg/kgBB. Parameter yang diukur meliputi berat badan, kadar NO serum (metode Griess), ekspresi gen eNOS (qPCR), kadar SGOT dan  SGPT. Hasil menunjukkan kombinasi ekstrak secara signifikan menurunkan berat badan dan meningkatkan kadar NO dibandingkan kelompok obesitas (p < 0,05), meningkatkan ekspresi gen eNOS serta secara (p< 0,05) signifikan menurunkan kadar SGOT dan SGPT . Penelitian ini mengindikasikan potensi kombinasi ekstrak kunyit dan pegagan sebagai agen preventif disfungsi endotel pada obesitas melalui peningkatan produksi NO dan regulasi ekspresi gen eNOS serta berperan sebagai hepatoprotektor. Kata Kunci: Ekstrak Kunyit, Ekstrak Pegagan, Ekspresi Gen eNOS, Jaringan Hati, Obesitas  Obesity is a pathological condition caused by excessive fat accumulation that increases the risk of metabolic disorders, including endothelial dysfunction characterized by decreased Nitric Oxide (NO) synthesis by the enzyme Endothelial Nitric Oxide Synthase (eNOS). This study aims to evaluate the effects of a combination of ethanol extracts of turmeric rhizome (Curcuma longa L.) and gotu kola leaves (Centella asiatica (L.) Urb) on serum NO levels and eNOS gene expression in the liver tissue of obese rats. This experimental study used male rats induced to become obese with a high-fat and high-carbohydrate diet for 60 days. The rats were divided into six groups: normal (negative control), obese (positive control), orlistat 10.8 mg/kgBW, turmeric extract 200 mg/kgBW, gotu kola extract 20 mg/kgBW, and turmeric-gotu kola combination 200:100 mg/kgBW. The measured parameters included body weight, serum NO levels (Griess method), eNOS gene expression (qPCR), SGOT and SGPT levels. The results showed that the combination of extracts significantly reduced body weight and increased NO levels compared to the obesity group (p < 0.05), increased eNOS gene expression, and significantly (p < 0.05) decreased SGOT and SGPT levels. This study indicates the potential of the combination of turmeric and pegagan extracts as a preventive agent for endothelial dysfunction in obesity through the enhancement of NO production and regulation of eNOS gene expression as well as acting as a hepatoprotector.
Potensi Anti-inflamasi Ekstrak Euphorbia heterophylla Desf.: Penelitian In Vitro dan In Vivo Susilawati, Elis; Pertiwi, Intan; Istiqomah, Aulia Nurfazri; Susilawati, Yasminwar; Levita, Jutti; Sumiwi, Sri Adi
Journal of Pharmascience Vol 12, No 2 (2025): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i2.23814

Abstract

Masyarakat secara tradisional menggunakan daun Kate Mas (Euphorbia heterophylla Desf.) untuk mengatasi kesulitan buang air besar. Penelitian sebelumnya melaporkan daun E. heterophylla memiliki aktivitas antioksidan DPPH dan anti-inflamasi pada tikus diinduksi karagenan. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian ekstrak E. heterophylla (EEH) secara in vitro pada suspensi sel darah merah yang diinduksi larutan hipotonik, serta untuk mengevaluasi efek EEH dalam uji in vivo pada hewan yang diinduksi dengan larutan putih telur 1%. Studi in vitro menggunakan metode HRBC (Human Red Blood Cell) dengan darah yang dirusak larutan hipotonik sebagai media uji yang diukur menggunakan spektrofotometer UV-vis pada panjang gelombang 560 nm. Metode in vivo dilakukan pada tikus yang dibagi secara acak menjadi lima kelompok (n=5): kelompok kontrol positif (Na-CMC), kelompok pembanding (diklofenak natrium 4,5 mg/kg BB), dan tiga kelompok uji (EEH 50, 100, 200 mg/kg BB). Semua kelompok diinduksi dengan putih telur 1% pada telapak kaki tikus. Parameter yang diukur adalah nilai IC50 dan persentase inhibisi edema pada kaki tikus setiap 30 menit selama 180 menit. Hasil: Skrining metabolit sekunder pada EEH menunjukkan adanya flavonoid, alkaloid, saponin, tanin, kuinon, dan steroid/triterpenoid. EEH menunjukkan nilai IC50 yang tergolong aktif sebagai anti-inflamasi dan mampu mengurangi volume edema. Kesimpulan: EEH berpotensi untuk dikembangkan sebagai pengobatan anti-inflamasi. Kata Kunci: Anti-Inflamasi, Euphorbia heterophylla, Putih Telur, Larutan Hipotonik, Human Red Blood Cell The community traditionally uses Kate Mas (Euphorbia heterophylla Desf.) leaves to alleviate constipation. Previous studies reported that E. heterophylla leaves possess DPPH antioxidant and anti-inflammatory activities in carrageenan-induced rats. This study aims to analyze the effect of E. heterophylla extract (EEH) administration in vitro on red blood cell suspensions induced by a hypotonic solution, and to evaluate the effects of EEH in vivo on animals induced with 1% egg white solution. The in vitro study was conducted using the Human Red Blood Cell (HRBC) method, where red blood cells were subjected to damage by a hypotonic solution as the test medium. The measurement was performed using a UV-Vis spectrophotometer at a wavelength of 560 nm. The in vivo method was conducted on rats randomly divided into five groups (n=5): positive control group (Na-CMC), comparison group (diclofenac sodium 4.5 mg/kg BW), and three test groups (EEH 50, 100, 200 mg/kg BW). All groups were induced with 1% egg white on the rat's paw. The parameters measured were the IC50 value and the percentage of edema inhibition in the rat’s paw every 30 minutes for 180 minutes. Results: Secondary metabolite screening of EEH showed the presence of flavonoids, alkaloids, saponins, tannins, quinones, and steroids/triterpenoids. EEH demonstrated an IC50 value classified as active anti-inflammatory and was able to reduce edema volume. Conclusion: EEH has the potential to be developed as an anti-inflammatory treatment.
KENALI DAN SADARI DIABETES SEJAK DINI: PROGRAM EDUKASI DAN SKRINING KESEHATAN MASYARAKAT DESA MANDALAWANGI, KECAMATAN NAGREG, KABUPATEN BANDUNG Sri Mas Hartini, Ni Nyoman; Susilawati, Elis; Supriadi, Dadih; Sutoro, Meylani; Lisni, Ida; Priyadi, Akhmad
Batara Wisnu : Indonesian Journal of Community Services Vol. 5 No. 3 (2025): Batara Wisnu | September - Desember 2025
Publisher : Gapenas Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53363/bw.v5i3.435

Abstract

Diabetes mellitus is one of the growing public health problems, particularly in rural areas such as Mandalawangi Village, Nagreg Subdistrict, Bandung Regency. Low public awareness of early detection and healthy lifestyle practices has contributed to the increasing prevalence of diabetes. This community service program was carried out using a participatory approach, which included interactive health education, random blood glucose screening, and lifestyle counseling. A total of 78 participants were involved and underwent pre-test and post-test assessments. The results showed that education significantly improved participants’ knowledge, as indicated by a statistically significant difference between pre-test and post-test scores (8.33 vs 8.94; p=0.0058). Screening results revealed that 15.4% of participants were categorized as pre-diabetic and 6.4% as diabetic. The establishment of the *Mandalawangi Healthy Community* serves as a follow-up initiative to ensure the sustainability of the program. Overall, the education and screening activities successfully enhanced community knowledge and awareness about diabetes and provided an important foundation for managing healthy lifestyles and preventing further complications.
Eksplorasi Potensi Antibakteri Senyawa Xanton Dalam Garcinia mangostana L. : Review Khoirunnisa, Intan; Rachmawati, Winasih; Susilawati, Elis
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 7, No 1 (2026): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v7i1.36090

Abstract

Xanthone compounds are a group of secondary metabolites commonly found in Garcinia mangostana plants. Several studies have shown that the content of these compounds in mangosteen plants exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria. This review aims to summarize various findings related to the antibacterial activity of mangosteen, both in extract form and pure xanthone compounds, as well as their mechanisms. A comprehensive literature search was conducted through PubMed, Mendeley, and Google Scholar databases using relevant keywords. Articles that met the inclusion criteria were reviewed to identify findings related to mangosteen's antibacterial activity. The results showed that several mangosteen extracts with different solvents, such as ethanol, methanol, and n-hexane, exhibited different metabolite profiles and activities against Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Among the various xanthone compounds, α-mangostin is the most extensively studied and has shown potential antibacterial activity, although other xanthone metabolites may exhibit similar activity. The antibacterial mechanisms of this compound include membrane damage, increased permeability, and inhibition of biochemical pathways for growth. In conclusion, xanthone compounds have great potential as natural antibacterial candidates, but the exploration of specific metabolites is still limited to α-mangostin, highlighting the need for further exploration of xanthone metabolites and their relationship with antibacterial activity.
Utilization of Dairy Cow Milk For Community Health Empowerment in Cibiru Wetan Village, Bandung Regency Jafar, Garnadi; Fatmawati, Fenti; Anggraeni, Vina Juliana; Ziska, Rahma; Pasha, ED Yunisa Mega; Susilawati, Elis
Warta Pengabdian Andalas Vol 32 No 4 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.04.512-519.2025

Abstract

In Cibiru Wetan, Bandung, cows' milk production reaches 5,000 liters per day, but most of it is not absorbed by the cooperative because it does not meet quality standards and is ultimately wasted. This highlights the gap between production potential and post-harvest processing capabilities at the farmer level. Training in processing milk into yogurt using simple technology can reduce waste while also opening up opportunities for public health and local entrepreneurship. The community service activity entitled "Training on the Utilization of Cow’s Milk as a Health Product in Cibiru Wetan Village, Bandung Regency" aimed to empower local dairy farmers in managing excess or substandard milk by turning it into yogurt, a functional health product. The method consisted of direct education, practical demonstrations, and mentoring in yogurt production using simple fermentation techniques, followed by pre- and post-test evaluations. A pre- and post-test evaluation showed an increase in participants’ knowledge from 45% to 89% of the 25 participants, 80% successfully produced yogurt with acceptable sensory quality, and 60% expressed interest in selling it as a home business. These outcomes indicate that the training not only improved technical skills but also fostered local entrepreneurship, contributing to SDG 3 (Good Health and Well-being) and SDG 8 (Decent Work and Economic Growth). Most participants succeeded in producing yogurt with acceptable sensory quality and expressed interest in selling it. The activity showed that with adequate training and support, local communities can utilize available resources to improve health and economic outcomes. This program also encouraged sustainable practices and provided a model that could be replicated in other rural areas with similar conditions. The results underline the importance of community-based education and technology transfer in promoting food security and local entrepreneurship.