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Fakultas Kedokteran Universitas Trisakti
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Ragam Spesies dan Karakteristik Habitat Nyamuk di Kecamatan Juai, Kabupaten Balangan, Provinsi Kalimantan Selatan Supriyono Supriyono; Suriyani Tan; Upik Kesumawati Hadi
ASPIRATOR - Journal of Vector-borne Disease Studies Vol 11 No 1 (2019): Jurnal Aspirator Volume 11 Nomor 1 2019
Publisher : Loka Litbang Kesehatan Pangandaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1445.822 KB) | DOI: 10.22435/asp.v11i1.186

Abstract

Filariasis merupakan penyakit tular vektor yang disebabkan oleh infeksi cacing filaria. Infeksi cacing ini selain mengakibatkan tingginya morbiditas dan kerugian sosial ekonomi, juga dapat menurunkan tingkat produktivitas masyarakat. Upaya pengendalian sudah dilakukan melalui program pengendalian vektor, namun belum maksimal. Hal ini disebabkan kurangnya informasi tentang bioekologi nyamuk vektor. Penelitian ini bertujuan untuk mengetahui jumlah jenis nyamuk, kepadatan, perilaku, karakteristik habitat, dan peranannya dalam penularan filariasis. Penelitian dilaksanakan pada bulan Januari sampai dengan April 2015 di Desa Hamarung dan Desa Hukai, Kecamatan Juai, Kabupaten Balangan, Provinsi Kalimantan Selatan. Penangkapan nyamuk dilakukan dengan metode Bare Leg Collection mulai dari pukul 18.00–06.00 WITA. Seluruh nyamuk hasil penangkapan diidentifikasi dan dibedah. Pengumpulan larva dilakukan pada habitat perkambangbiakan potensial. Hasil penelitian menemukan 15 spesies nyamuk yang terdiri dari lima genus yaitu Culex, Mansonia, Anopheles, Armigeres, dan Aedes. Lima jenis nyamuk yang banyak tertangkap adalah Cx. tritaeniorhynchus (36,80%), Cx. quinquefasciatus (29,60%), Ma. dives (11,73%), Ma. annulata (10,04%), dan Ma. uniformis (4,62%). Puncak aktivitas Cx. quinquefasciatus dan Cx. tritaeniorhynchus mengisap darah orang di kedua desa terjadi pada pukul 21.00–00.45. Berdasarkan jenis habitat, nyamuk genus Culex, Mansonia, dan Anopheles cenderung terdapat dalam satu habitat yaitu rawa. Hasil pembedahan nyamuk tidak ditemukan larva cacing filaria (L1, L2, L3).
Peranan Bakteri Wolbachia pada Patogenesis Filariasis Suriyani -
Cermin Dunia Kedokteran Vol 41, No 2 (2014): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v41i2.1163

Abstract

Diperkirakan saat ini sekitar 150 juta penduduk di seluruh dunia terinfeksi filariasis terutama penduduk di kantong-kantong kemiskinan di daerah tropis termasuk Indonesia. Penyebab filariasis berupa nematoda jaringan, yaitu Wuchereria bancrofti, Brugia malayi, dan Brugia timori. Wolbachia pipientis sebagai bakteri yang diketahui berendosimbion dengan cacing filaria mempunyai peranan pada patogenesis inflamasi filariasis. Inflamasi diakibatkan oleh lipoprotein Wolbachia yang terpapar pada respon imun manusia diperantarai jalur TLR2/6 saat bakteri Wolbachia terbebas ke peredaran darah setelah kematian dan degenerasi cacing dewasa maupun microfilaria. Bakteri Wolbachia hanya mempunyai gen Ltg dan LspA untuk biosintesis lipoprotein, tetapi tidak mempunyai gen Lnt mengisyaratkan bahwa lipoprotein Wolbachia berbentuk diasil sehingga merupakan ligan  yang cocok dengan TLR2/6.  Inflamasi akibat lipoprotein Wolbachia akan memicu peningkatan sitokin pro inflamasi. Sitokin proinflamasi akan meningkatkan induksi VEGF-A dan VEGF-C yang sangat berkontribusi pada patogenesis limfedema dan hidrokel pada penderita filariasis.   It is estimated that more than 150 million people in the world are infected by the filarial disease, especially among poor communities in tropic regions, including Indonesia. The cause of this lymphatic filariasis are Wuchereria bancrofti, Brugia malayi, and Brugia timori. Wolbachia pipientis, an obligate intracellular bacterium, is an endosymbiont of the filarial parasite, have a very important role in the pathogenesis of lymphatic filariasis.  Inflammation is caused by the Wolbachia lipoprotein which are liberated after the death of adult parasite or microfilariae and exposed to the host immune system and is mediated by TLR2/6. Wolbachia only have  Ltg dan LspA genes for the lipoprotein biosynthesis, but do not possess the Lnt gene.  These findings confirm that Wolbachia lipoprotein is diacylated, so it is a match ligand with TLR2/6.  Inflammation caused by Wolbachia lipoprotein increased pro-inflammation cytokine. The pro-inflammation cytokine  will cause induction of  VEGF-A dan VEGF-C, contributing to the lymphedema and hydrocele pathogenesis in lymphatic filariasis. 
Penyuluhan Tentang Demam Berdarah Dan Pencegahannya Yuliana; Machrumnizar; Suriyani; Arleen Devita
JURNAL ABDIMAS KESEHATAN TERPADU Vol. 1 No. 2 (2022): Jurnal Abdimas Kesehatan Terpadu
Publisher : Fakultas Kedokteran Gigi, Universitas Trisakti bekerjasama dengan Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (363.647 KB) | DOI: 10.25105/jakt.v1i2.15477

Abstract

Dengue hemorhagic fever (DHF) is an infection caused by dengue virus. Dengue is a virus that is transmitted from Aedes Spp mosquito, the fastest growing mosquito in the world and has transmitted dengue virus. The prevalence of DHF until July 2020 has reached 71.633 in Indonesia, and 4.227 cases only in DKI Jakarta province. We usually don’t find new case on July, but this year we still find new cases on July. This should increase our vigilance, especially at this time when there is a pandemic of COVID-19 cases. The purpose of this activity is to increase public knowledge about dengue fever so that they can prevent dengue fever in their area. This activity is carried out through seminar using the zoom application because conditions in the field do not allow offline activities to be held. The activity will be held on Saturday, April 23, 2022. The results obtained through this PKM activity is an increase in the level of participants' knowledge about DHF as evidenced by an increase in post-test scores after attending the seminar. The conclusion of this PKM activity went well because of the support from all related parties from institutions, solid teams, and partners who actively participated. The shortage of this PKM activity is that the activities are carried out online because the conditions are still not conducive to do an offline activity. The advice we can give is to carry out PKM activities again with the same partner with different health topics according to the conditions that exist in the partners.
THE COMMUNITY DEVELOPMENT AND LEPROSY SELF-CARE GROUPS IN A FIRST-LEVEL OF HEALTH FACILITIES Rina Kusumaratna; Suriyani Tan
AMMA : Jurnal Pengabdian Masyarakat Vol. 1 No. 05 (2022): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Neglected Tropical Diseases (NTDs) remain a public health problem in 149 tropical and subtropical countries, including Indonesia. NTDs are closely related to poverty and low levels of hygiene and sanitation. In Indonesia alone, there are more than 5 types of neglected tropical diseases, one of which is leprosy. Leprosy, also known as Morbus Hansen, caused by the bacterium Mycobacterium leprae, is a disease with a long history. Leprosy can be found in several scriptures and has been known since the time of Ancient Egypt around 2000 years BC. This disease is often considered a curse on the sufferer and until now this stigma continues to stick to the sufferer. Stigmatization and social discrimination in leprosy patients make leprosy sufferers isolated from the surrounding community so that the outreach process by health workers becomes difficult. Guidance for leprosy patients in the form of counseling was carried out before the pandemic through self-care groups for leprosy sufferers, and evaluations were carried out after the pandemic to assess improvements in literacy levels and understanding of the group members. The result of this community is an increase in literacy about the adoption of water, sanitation, and hygiene (WASH) among the members of self-care groups in first-level of health facilities.
Peningkatan Pengetahuan Tentang Infeksi Parasit Penyebab Diare dan Sanitasi Lingkungan Suriyani Tan; Machrumnizar Machrumnizar
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 2 (2023): AMMA : Jurnal Pengabdian Masyarakat (INPRESS)
Publisher : CV. Multi Kreasi Media

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Abstract

Diarrhea in one of the leading causes of child mortality worldwide. According to World Health Organization data, there are about 1,7 billion cases of diarrhea in children. Diarrhea due to parasitic infection is widespread throughout developing countries. This includes limited access to health services, socio-economic problems, population density, slum settlements, malnutrition, geographic factors, poor hygiene and waste management, including lack of access to clean water and sanitation.
Penyuluhan Imunisasi Tetanus Toksoid Untuk Calon Pengantin Dan Wanita Usia Subur Di Fasilitas Kesehatan Tingkat Pertama Rina kusumaratna; Suriyani Tan; Witriastika Suci
JUARA: Jurnal Wahana Abdimas Sejahtera Volume 4, Nomor 2, Juli 2023
Publisher : Jurusan Teknik Lingkungan Fakultas Arsitektur Lanskap dan Teknologi Lingkungan, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25105/juara.v4i2.13965

Abstract

Tetanus is a serious disease caused by spores of the bacterium Clostridium tetani. Tetanus infection has no boundaries as people of all ages can be infected and it is still a public health problem today, especially for pregnant women and newborns. Neonatal tetanus (TN) is the tetanus infection in infants aged 3 – 28 days after birth and maternal tetanus (MT) is the infection that occurs during pregnancy and up to 6 weeks after delivery. Tetanus infection generally occurs if the delivery is not carried out in health facilities with adequate equipment and is known as one of the most common causes of death during childbirth. The aim of this Community Service activity was to provide counseling about the importance of Tetanus Toxoid (TT) T immunization for prospective brides and WUS who came to the mother and children out-patient clinic at the Primary Health Care. Cadres those bearing an important role in expanding health information for the community were also involved in this program. This Community Service activity held counseling for the prospective bride and fertile-aged women, while the cadres were given refreshing additional knowledge about TT immunization. The results of this activity were increasing the cadres’ knowledge about TT immunization, and those prospective-bride and fertile-aged women were also encouraged to carry out active TT immunization at the Primary Health Care. There is also a need for cross-sector collaboration with the Religious Affairs office in the application of evidence of TT immunization for prospective-bride as a mandatory requirement that could be implemented properly.
Korelasi Kadar Interleukin-6 (IL-6) dan C-Reactive Protein (CRP) Sebelum dan Setelah Aktivitas Fisik pada Pria Umur 18-30 Karlina Mahardieni; Julian Chendrasari; Miladya Syamsu; John Steward Castellano Lelapari; Julia Aina Syafitri; Suriyani Suriyani
Jurnal Multidisiplin Dehasen (MUDE) Vol 5 No 2 (2026): April
Publisher : LPPJPHKI Universitas Dehasen Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37676/mude.v5i2.9352

Abstract

This study examined the relationship between Interleukin-6 (IL-6) and C-Reactive Protein (CRP) levels before and immediately after moderate-intensity stair climbing exercise in healthy young adults. Twenty-seven subjects performed a 5-minute stair climbing intervention at 60-80% of their maximum heart rate. IL-6 and CRP levels were measured using ELISA before and immediately after exercise. Pearson correlation analysis showed a very low and non-significant correlation between IL-6 and CRP before exercise (r=−0.004, p = 0.986). After exercise, there was an increase in positive correlation (r=0.277) but it remained statistically non-significant (p = 0.180). These results indicate that physical activity of this duration and intensity does not trigger a strong systemic inflammatory response, and thus IL-6 and CRP levels did not show a significant relationship. Differences in the peak timing of these biomarkers and individual physiological adaptations likely influenced these findings. Further studies with biomarker measurements at multiple time points and varying exercise intensities are needed to better understand the dynamics of IL-6 and CRP responses post-exercise. These findings provide important insight into inflammatory responses to moderate exercise in a healthy young population.
Sosial-Ekonomi dan Pengetahuan Terhadap Perspektif Lansia Penderita TB Paru di Kota Bengkulu Feri Surahman Saputra; Yance Hidayat; Jipri Suyanto; Diki Bima Prasetio; Suriyani Tan
Malahayati Nursing Journal Vol 7, No 5 (2025): Volume 7 Nomor 5 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i5.17323

Abstract

ABSTRACT Especially in older individuals, perspective can serve as the basis for health behavior. This perspective measures the extent to which tuberculosis patients adhere to the treatment process based on pre-established guidelines. The presence of a negative patient attitude directly correlates with an increased likelihood of non-adherence to therapy, thereby giving birth to additional complications, such as medication resistance. Investigation of the variables influencing the viewpoint of older individuals with Tuberculosis in Bengkulu City. The research utilised a cross-sectional methodology and included a total of 153 participants in Bengkulu City. The sample selection method utilises a multistage random sampling methodology applied during a research period of one month. The data analysis procedure utilizes both univariate and logistic regression estimation techniques. The findings indicated that almost 50% of the participants were male, nearly 50% had completed primary education, nearly 50% were employed as farmers, nearly 50% were divorced, over 50% earned the Regional Minimum Wage, nearly 50% had limited knowledge, and nearly 50% had a negative outlook. Moreover, the findings indicated a correlation between gender, secondary education, agricultural occupation, marital status, income, and knowledge as perceived by senior individuals with tuberculosis in the Bengkulu City Region, with a statistically significant p-value of less than 0.05. The results suggest a correlation between the viewpoint of the respondent and the elements inherent to him. Hence, in order to shift the respondent's viewpoint towards a favorable one and enhance the patient's own treatment process, it is imperative to have active support from all stakeholders, including the family, the community, and the medical team. The adoption of a positive attitude by patients can foster motivation to comply with the treatment suggestions provided by the doctor, thereby potentially resulting in a reduction in the occurrence of tuberculosis. Improved health of the community can ensue as a consequence. Keywords: Perspective of Older People with Tuberculosis, Gender, Socio-Economics. ABSTRAK Perspektif dapat menjadi dasar dalam hal berperilaku kesehatan, khususnya pada pasien lansia. Perspektif ini menjadi penyebab penentu kepatuhan pasien TB dalam menjalani proses pengobatan yang sesuai dengan aturan yang telah ditetapkan. Semakin buruk perspektif pasien tersebut, maka peluang tidak patuh dalam menjalani pengobatan akan semakin tinggi yang dapat menyebabkan masalah lain muncul, yaitu resistensi obat. Untuk Mengetahui faktor yang berhubungan dengan perpsektif lansia penderita TB di Kota Bengkulu. Penelitian ini menggunakan desain cross sectional yang dilaksanakan di Kota Bengkulu dengan jumlah respoden sebanyak 153 responden. Teknik dalam menseleksi sampel menggunaka teknik multistage random sampling dengan lama penelitian selama 1 bulan. Sedangkan analisis data menggunakan uji univariat dan uji logistic regression. Dari hasil menunjukan hasil bahwa hampir sebagian responden berjenis kelamin laki-laki, hampir sebagian dari responden memiliki pendidikan dasar, hampir sebagian dari responden memiliki background pekerjaansebagai petani, hampir sebagian dari responden memiliki status cerai, lebih dari setengah dari responden memiliki pendapatan UMR, hampir Sebagian dari responden memiliki pengetahuan kurang baik, dan lebih dari setengah dari responden memiliki perspektif kurang baik. Selaian itu hasil menunjukan juga bahwa adanya hubungan antara jenis kelamin, Pendidikan menengah, background pekerjaan sebagai petani, status perkawinan, pendapatan dan pengetahuan dengan perspektif lansia penderita TB di Kawasan Kota Bengkulu dengan nilai p-value di bawah 0.05. Dari hasil menunjukan hasil bahwa komponen faktor yang berasal dari diri responden memiliki hubungan dengan perpsektif dari responden itu sendiri. Oleh karena itu, untuk merubah perspektif responden tersebut menjadi baik sehingga dapat menstimulus dalam proses pengobatan pasien itu sendiri, diperluhkan dukunga dari semua kalangan, baik dari keluarga, Masyarakat dan dari team medis itu sendiri. Sehingga penderita dapat berpikir positif dan termotivasi untuk melakukan pengobatan sesuai ajuran dari dokter dan angkah kejadian dari TB itu sendiri memiliki peluang menjadi menurun. Sehingga dapat meningkatkan derajat Kesehatan di dalam komunitas itu sendiri. Kata Kunci: Persepektif Lansia Penderita TB, Jenis Kealmin, Sosial-Ekonomi.
Penyuluhan Tentang Kesehatan Gigi Dan Mulut Pada Anak Sekolah Dasar Suriyani Tan; Machrumnizar Machrumnizar
AMMA : Jurnal Pengabdian Masyarakat Vol. 1 No. 05 (2022): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

Sugary foods and drinks are defined as foods that contain high levels of sugar. The high sugar content in these foods or beverages generally comes from added sweeteners. Sugary foods and drinks affect human health. If sugary foods and drinks are consumed for a long period of time and in excessive proportions, health problems such as obesity, diabetes mellitus and dental and oral health can occur. School-aged children are consumers who consume a lot of sugary foods and drinks. The incidence of dental caries also often occurs in school children due to consumption of sugary foods and drinks. The purpose of this community service activity is to provide counseling to school children about the risks of consuming sugary foods and drinks, as well as provide education about dental and oral health.
Edukasi Pemakaian Masker, Peningkatan Pengetahuan Tentang Penyakit Pernapasan, Dan Skrining Kesehatan Machrumnizar Machrumnizar; Suriyani Tan
AMMA : Jurnal Pengabdian Masyarakat Vol. 2 No. 12 : Januari (2024): AMMA : Jurnal Pengabdian Masyarakat
Publisher : CV. Multi Kreasi Media

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Abstract

More than four million people die each year from respiratory problems, which also affect hundreds of millions more. This disease has detrimental effects on the family, society, and the health and well-being of the patient. especially those living in low- and middle-income countries, where people are daily exposed to indoor air pollution from solid fuels used for cooking and heating. The biggest significant risk factor for respiratory disease in high-income countries is tobacco use. WHO data for 2020 shows that Lower Respiratory Infection Disease and Chronic Obstructive Pulmonary Disease rank number 3 and 4, at 6.1% and 5.8% respectively. There are eight lung diseases that are a public health problem in Indonesia and are included in the scope of the Indonesian Ministry of Health's environmental health and disease control program, including Tuberculosis, Acute Respiratory Infection (ARI), Bronchial Asthma, Lung Disease, Chronic Obstructive, Lung Cancer, Air Pollution and Climate Change, Combating Smoking Problems, Emerging & New Emerging Diseases (including COVID-19). Since WHO declared the COVID-19 pandemic in March 2020, Indonesia has carried out public interventions to stop the pandemic, including pharmaceutical and non-pharmaceutical actions (wearing masks, travel restrictions, closing schools, and postponing public events). Non-pharmaceutical interventions have a greater impact on infectious diseases than pharmaceutical interventions, despite the fact that pharmaceutical strategies can target specific organisms.
Co-Authors Alfred Pakpahan David David David Tjahyadi Devita, Arleen Diki Bima Prasetio Endrico Xavierees Tungka Feri Surahman Saputra Hendra Kurniawan IMELDA YUNITRA Jipri Suyanto Jipri Suyanto John Steward Castellano John Steward Castellano Lelapari Julia Aina Syafitri Julian Chendrasari JULIAN CHENDRASARI Karlina Mahardieni KARLINA MAHARDIENI Machrumnizar Machrumnizar Miladya Syamsu Monica Dwi Hartanti Monica Dwi Hartati Putri Aliyah Denizar Rina K. Kusumaratna Rina kusumaratna Rina Kusumaratna Sisca Sisca Sisca Sisca Sisca Sisca Supriyono, Supri Triasti Khusfiani Triasti Kusfiani Upik Kesumawati Hadi Witriastika Suci Yance Hidayat Yani Kurniawan Yani Kurniawan Yuliana Yuliana Yuliana, Yuliana