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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kesehatan Masyarakat Journal of Health Education Indonesian Journal of Medicine Oto Rhino Laryngologica Indonesiana Medica Hospitalia Diponegoro International Medical Journal (DIMJ) Indonesian Journal of Cancer
Dewi, Anna Mailasari Kusuma
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Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Determinant of Voice Handicap Index Degree as Dysphonia Patients’ Quality of Life Indicator Yusuf, Muhammad; Dewi, Anna Mailasari Kusuma; Yunika, Kanthi; Yusmawan, Willy; Farokah, Farokah; Budiarti, Rery; Muyassaroh, Muyassaroh
JHE (Journal of Health Education) Vol 6 No 1 (2021): April 2021
Publisher : Universitas Negeri Semarang cooperate with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jhe.v6i1.42118

Abstract

Background: Dysphonia will interfere with communication which will have an impact on social life such as depression, disrupt activities, work and can affect the quality of life. Dysphonia risk factors such as age, sex, duration of illness and etiology will affect the course of it. The purpose of this study was to identify risk factors for with the degree of Voice Handicap Index (VHI) as an indicator of dysphonia patients.Methods: Analytical descriptive study with cross-sectional design in dysphonia patients, the sample was determined as many as 62 who met the inclusion criteria. Quality of life was assessed by the VHI questionnaire. VHI degrees are classified into mild and moderate-severe. Data analysis using chi-square test and multivariate logistic regression. Results:Thirty-two (51.6%) subjects were women. Mean age was 47.26 +12.2. The most common causes of dysphonia (85.5%) were due to organic disorders and laryngopharyngeal reflux (LPR) is the most common cause (37.1%) of all organic dysphonia disorders. Analysis of risk factors for age, gender, etiology of dysphonia and duration of illness with VHI degree were p = 0.282, p =0.76, p= 0.067, p= 0.001, respectively. Duration of illness ≥2 weeks has a 38.3x risk to severity VHI compared to <2 weeks. Conclusion: The duration of illness is a determinan related to of the degree of VHI that quality of life indicator in dysphonia patients. Key Words: Risk factors, Dysphonia, Voice Handicap Index
Determinant of Voice Handicap Index Degree as Dysphonia Patients’ Quality of Life Indicator Yusuf, Muhammad; Dewi, Anna Mailasari Kusuma; Yunika, Kanthi; Yusmawan, Willy; Farokah, Farokah; Budiarti, Rery; Muyassaroh, Muyassaroh
Journal of Health Education Vol 6 No 1 (2021): April 2021
Publisher : Universitas Negeri Semarang cooperate with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jhe.v6i1.42118

Abstract

Background: Dysphonia will interfere with communication which will have an impact on social life such as depression, disrupt activities, work and can affect the quality of life. Dysphonia risk factors such as age, sex, duration of illness and etiology will affect the course of it. The purpose of this study was to identify risk factors for with the degree of Voice Handicap Index (VHI) as an indicator of dysphonia patients.Methods: Analytical descriptive study with cross-sectional design in dysphonia patients, the sample was determined as many as 62 who met the inclusion criteria. Quality of life was assessed by the VHI questionnaire. VHI degrees are classified into mild and moderate-severe. Data analysis using chi-square test and multivariate logistic regression. Results:Thirty-two (51.6%) subjects were women. Mean age was 47.26 +12.2. The most common causes of dysphonia (85.5%) were due to organic disorders and laryngopharyngeal reflux (LPR) is the most common cause (37.1%) of all organic dysphonia disorders. Analysis of risk factors for age, gender, etiology of dysphonia and duration of illness with VHI degree were p = 0.282, p =0.76, p= 0.067, p= 0.001, respectively. Duration of illness ≥2 weeks has a 38.3x risk to severity VHI compared to <2 weeks. Conclusion: The duration of illness is a determinan related to of the degree of VHI that quality of life indicator in dysphonia patients. Key Words: Risk factors, Dysphonia, Voice Handicap Index
Hearing Aids and The Quality of Life of Children with Hearing Loss Cahyani, Nastiti Dwi; Dewi, Anna Mailasari Kusuma; Ruspita, Dian Ayu; Muyassaroh, Muyassaroh
KEMAS: Jurnal Kesehatan Masyarakat Vol 17, No 4 (2022)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v17i4.26574

Abstract

Hearing loss in children may cause social isolation and poor communication skills, potentially affecting mental disorders and quality of life. Hearing aids (HA) provide auditory stimuli that can improve children's speech ability and influence their quality of life. A cross-sectional study in three special schools-B (SLB-B) in Semarang was carried out. A total of 82 children (7-12 years old) with severe hearing loss with or without hearing aids were included. Quality of life was assessed by the Hearing Environments and Reflection on Quality of Life (HEAR-QL) questionnaire. The results showed that 48 (58.54%) subjects used hearing aids, and 34 (41.46%) did not use hearing aids. The average subject's age was 10.77±1.56 years old. Hearing-aid use was associated with a good quality of life of children with hearing loss (p0.001). Good quality of life was found in 68.8% of children with hearing aids compared to only 2.9% in children without hearing aids. Duration of hearing-aid use (p0.001), mother education (p0.006) was associated with good quality of life of children, whereas gender (p=0.49), number of siblings (p=0.06), and socioeconomic status (p=0.63) were not. The quality of life of children who use hearing aids is better than without hearing aids.
Factors Associated with Hearing Loss in Helicopter Aircrew of Indonesian Army Aviation Center, Semarang Muyassaroh, Muyassaroh; Sayuti, Fajri Imam; Ruspita, Dian Ayu; Dewi, Anna Mailasari kusuma; Budiarti, Rery; Naftali, Zulfikar; Widodo, Pujo
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 12, No 2 (2021): December 2021
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (433.258 KB) | DOI: 10.30659/sainsmed.v12i2.12819

Abstract

Introduction: Hearing loss and tinnitus may occur in pilots due to exposure of the high noise level (ranges from 104-110 dB) generated by aircraft/helicopters. In addition, flying time, acoustic trauma, diabetes mellitus, hypertension and smoking are risk factors of hearing loss. Objective: to identify the factors associated with hearing loss in the crew of the Indonesian Army Aviation Center, SemarangMethods: in the cross-sectional research, 114 military helicopter aircrews aged 20-58 years, working for the Army Aviation Center in Semarang were included. The exclusion criteria were history of previous ear surgery, infection of the outer and middle ear, the use of ototoxic drugs (kanamycin, cisplatin and carboplatin). The level of hearing loss and tinitus was assessed by otoscopy and audiometry. Whereas, tinnitus was obtained from the history taking. Data were analyzed using chi-square test and fisher's exact and Yates’s correction.Results: One hundred and fourteen subjects (mean age of 26.54 + 4.72) were included. Several factors such as flight time (p = 0.698), acoustic trauma (p = 0.151), diabetes mellitus (p = 0.596), smoking (p = 0.222), hypertension (p = 0.356) were not associated with sensorineural hearing loss. Several factors such as flight time (p = 0.706), acoustic trauma (p = 0.5160), diabetes mellitus (p = 0.789), smoking (p = 0.495), hypertension (p = 0.112) were not associated with tinnitus.Conclusion: There is no association between flight time, acoustic trauma, diabetes mellitus, hypertension, and smoking and hearing loss.
Effect of Nigella sativa extract on nasal mucosal inflammation in rats exposed to cigarette smoke Alamanda, Fathika; Dewi, Anna Mailasari Kusuma; Marliyawati, Dwi; Santosa, Yanuar Iman
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 1 (2024): June 2024
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v15i1.22833

Abstract

Cigarette smoke contains toxic compounds that can initiate an inflammatory reaction and infiltrate inflammatory cells. The nasal mucosa is the initial part of the respiratory system that comes into contact with irritating chemicals such as cigarettes. Prior studies indicated that Nigella sativa extract (NS) has thymoquinone, a bioactive compound with anti-inflammatory properties. Our study aims to determine the effect of different doses of NS on inflammation of the nasal mucosa in Wistar rats exposed to cigarette smoke. The study employed an experimental post-test-only control group design. Twenty-five Wistar rats were randomly assigned to one of the five groups: negative control (K-), positive control (K+), and three treatment groups of P1, P2, and P3 receiving NS at the dose of 0.5, 1, and 1.5 g/kg bw/day, respectively. All treatment groups and the positive control group were exposed to smoke from 4 cigarettes/day for 28 days. The degree of inflammatory cell infiltration was evaluated using a histological scoring : 0 if normal; 1 if infiltration was less than 1/3; 2 if infiltration was between 1/2 and 2/3, 3 if infiltration of more than 2/3 indicating normal, less than 1/3, 1/3 to 2/3, and more than 2/3, respectively. The degree of inflammatory cell infiltration in group: K(-): 1.00 ±0.00, K(+): 1.00±0.00, P1: 1.00±0.00, P2: 1.00±0.37, and P3: 1.00±0.33. The Kruskal-Wallis test showed a p-value of 0.001, indicating a significant difference. The Mann-Whitney test revealed significant differences between the K+ and P2 groups (p=0.032), K+ and P3 groups (p=0.013), and P1 and P3 groups (p=0.049). In conclusion, NS can decrease the presence of inflammatory cells in the nasal mucosa in Wistar rats exposed to cigarette smoke.
Penatalaksanaan Wanita Dengan Rinore Lcs Dan Meningoensefalokel Akibat Patensi Sternberg’s Canal Iriani, Desy; Dewi, Anna Mailasari Kusuma; Priambada, Dody
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (609.649 KB) | DOI: 10.36408/mhjcm.v8i1.574

Abstract

Latar belakang : Rinore liquor cerebro spinal (LCS) adalah kebocoran LCS yang terjadi karena adanya defek pada basis kranii sehingga terdapat hubungan antara intrakranial dengan cavum nasal. Sternberg’s canal merupakan defek kongenital di dinding lateral sphenoid. Kasus ini menjelaskan etiologi serta penatalaksanaan pasien rinore LCS dan meningoensefalokel. Laporan kasus : Dilaporkan wanita usia 32 tahun dengan keluhan keluar cairan hidung kiri terkadang mengalir deras, hilang timbul selama 1 tahun disertai pusing. Pemeriksaan CT scan menunjukkan defek tulang di lateral sfenoid kiri disertai lesi isodens di sinus sfenoid, hal ini diperjelas dengan hasil MRI yang menggambarkan meningoensefalokel. Pasien dilakukan operasi sfenoidektomi dengan endoskopi kerjasama dokter THT dan Bedah Saraf, dilakukan pemasangan lumbar drain, identifikasi lokasi kebocoran LCS dan pemasangan graft lemak. Evaluasi 6 minggu pasca operasi, keluhan keluar cairan hidung dan pusing sudah tidak ada. Pasien mengalami perbaikan dan peningkatan kualitas hidup. Pembahasan : Kasus rinore LCS mempunyai beberapa etiologi, setelah melalui anamnesis, pemeriksaan fisik dan pemeriksaan penunjang, didapatkan etiologi pada kasus ini yaitu akibat patensi Sternberg’s canal. Pada kasus ini dilakukan penanganan operatif karena keluhan sudah lama dan etiologi sudah jelas. Kerjasama multidisiplin diperlukan, untuk pemasangan lumbar drain dan pemasangan graft lemak dengan kerjasama yang baik. Kesimpulan : Penatalaksanaan rinore LCS dibagi menjadi konservatif dan operatif. Keberhasilan penanganan rinore LCS bergantung pada tajamnya penilaian dokter dalam memutuskan tatalaksana yang tepat agar pasien dapat tertangani dengan cepat sebelum terjadi komplikasi.
Correlation between Preoperative Osteitis Degree with Postoperative Endoscopic Score in Chronic Rhinosinusitis Apriansyah, Apriansyah; Dewi, Anna Mailasari Kusuma; Ningrum, Farah Hendara
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.784

Abstract

BACKGROUND: In chronic rhinosinusitis patients, there is a subgroup of patients with persistent symptoms after treatment, who often shows bone thickening and remodeling in their paranasal sinuses and described as osteitis. Osteitis can be evaluated by several methods, one of which is the Global Osteitis Score (GOS) AIM: To analyse the correlation between preoperative osteitis degree with the postoperative endoscopic scores in chronic rhinosinusitis METHOD: It was an observational study with cross-sectional design. We use GOS from CT scan before surgery and Lund Mackay’s endoscopic score 4 weeks after Functional Endoscopy Sinus Surgery (FESS). The analysis performed with Spearman correlation test. RESULT:  There were 30 patients as subjects. There statistical analysis test between preoperative osteitis degree with post operative endoscopic score showed p = 0.296 with r = 0.197. The analysis result between risk factors for wound healing with the postoperative endoscopic score were allergic rhinitis (p = 1.000), polyps (p = 0.624), and smoking (p = 0.309) CONCLUSION: There is no significant correlation between preoperative osteitis degree with the postoperative endoscopic score, but there is a tendency for a positive correlation between preoperative osteitis degree with the postoperative endoscopic score. There was no significant correlation between allergic rhinitis, polyps, and smoking habits with postoperative endoscopic score
The Effect of 1% Povidone Iodine Mouthwash on The Incidence of Oral Mucositis and Odynophagia in Patients with Head and Neck Malignancy Handayani, Peny; Budiarti, Rery; Yusmawan, Willy; Antono, Dwi; Dewi, Anna Mailasari Kusuma; Widodo , Pujo
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 2 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i2.854

Abstract

BACKGROUND: Oral mucositis is an injury of normal mucosal tissue with an acute inflammation of the oral, tongue, and pharyngeal mucosa after exposure to chemo-radiotherapy. Post chemoradiotherapy oral mucositis is commonly accompanied by painful swallowing or odynophagia. Povidone iodine 1% is an antiseptic mouthwash that widely used to prevent infections in the oral cavity. OBJECTIVE: The aim of this study was to determine the effect of 1% povidone iodine mouthwash on the incidence of oral mucositis in patients with head and neck malignancy at Dr. Kariadi General Hospital Semarang.    METHOD: This study was single random blinded experimental study, with total samples of 44 patients with head and neck malignancy after chemoradiotherapy. The samples divided into treatment group of 22 samples with 1% povidone iodine mouthwash and control group of 22 samples with NaCl 0.9% recruited using single random sampling at Dr. Kariadi Semarang General Central Hospital in 2022. The effect of 1% povidone iodine mouthwash on the incidence of oral mucositis and odynophagia was analyzed using the Fischer Exact and Mann Whitney test. RESULT: In the 1% povidone iodine mouthwash group day 15th, 21 patients (95.5%) were found without mucositis and 1 patient (4.5%) with mucositis oral grade I. In the 1% povidone iodine mouthwash group, 21 people (4.5%) were found without odynophagia and 1 people (4.5%) had odynophagia. There was an association between oral mucositis and odynophagia on povidone iodine 1% group (p < 0.05).        CONCLUSION: Povidone iodine 1% mouthwash can affect the incidence of oral mucositis in patients with head and neck carcinoma. Povidone iodine 1% mouthwash can reduce the incidence of oral mucositis and odynophagia compared to placebo in patients with head and neck carcinoma.
The Association between Obstructive Sleep Apnea and Glycated Haemoglobin A1c (Hba1c) Level in Diabetes Mellitus Type II Patient Dewi, Anna Mailasari Kusuma; Handayani, Peny; Rachma, Devi Elvina; Limijadi, Edward Kurnia Setiawan
Diponegoro International Medical Journal Vol 3, No 2 (2022): December 2022
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v3i2.15191

Abstract

Abstract Background: Obstructive sleep apnea (OSA) is a chronic condition characterized by repetitive episodes of upper airway collapse, apnea, and arousal during sleep. OSA and type 2 diabetes mellitus (T2DM) are common comorbid conditions. Haemoglobin A1c (HbA1c) is an approximation of an individual’s average blood glucose level for the prior two to three months, and therefore is considered to be a major index for monitoring glycaemic control in diabetic patientsObjective: This study aimed to examine the association between OSA and HbA1c levels in T2DM patients.Methods: This was a cross-sectional study. The study assesses the association between OSA and HbA1c levels in 75 T2DM patients. OSA in the patient was asses with Epworth Sleepiness Scale (ESS) questionnaire. HbA1c values were obtained from the patient’s records. Data presented in mean ± SD, max, and min. Correlations analyses using Pearson correlation coefficient with p < 0.05 were considered statistically significant.Results: A total of 75 T2DM has a mean BMI were 25.26 ± 48.31 kg/m2 with mean HbA1c levels of about 7.1 ± 0.19%. The mean ESS score was 5 ± 0.429. The very weak correlation between OSA and BMI was statistically significant, r = 0.213; p = 0.047. Meanwhile, a very weak correlation between OSA and HbA1c levels was not statistically significant, r = 0.137; p = 0.242Conclusion: Among adults with T2DM, the correlation between OSA with HbA1c was not statistically significant
RISK FACTORS FOR SMELL AND TASTE DISORDER IN MILD AND MODERATE COVID-19 IN SEMARANG Dewi, Anna Mailasari Kusuma; Astika, Ismiar; Farokah, Farokah; yunika, kanti; Marliyawati, Dwi
Diponegoro International Medical Journal Vol 4, No 2 (2023): December 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i2.17892

Abstract

ABSTRACK Background: COVID-19 can make smell and taste disorder due to Angitensin Converting Enzyme 2 (ACE2) binding to olfactory tractus and taste bud that affected by gender, age, comorbid and COVID-19 severerity.Aim: To analyze age, gender, comorbid and COVID-19 severity as risk factor for smell and or taste disorder in mild and moderate Covid -19 patient in SemarangMethods: Observational research used cross section design. Sample is COVID-19 patients age >10 years old with severity mild and moderate nonhospitalize that record on Health Center of Semarang City June – July 2021. Sampling metode using purposive sampling with secondary data. Association between variable analyze using Chi square or Fisher exact test, multivariate analyze with logistic regression.Results: Research on 4337 people, 2.0% smell disorder and 0.5% taste disorder. Prevalence COVID-19 mostly on women 50.5% and adult (20-60 years old) 82.5%. Risk factor gender, age and COVID-19 severity is not associated with smell and taste disorder on COVID-19 patients (p<0.05). Chronic liver disease as a risk factor only for smell disorder on COVID-19 patients (p 0.04, CI 3.029-786.993, RP 48.828). Conclusion: Chronic liver disease is a comorbid as a risk factor for smell disorder ini COVID-19 patients at Semarang. age, gender and other comorbid not as a risk factor for smell and or taste disorder. 
Co-Authors . Apriansyah Alamanda, Fathika Antono, Dwi Arsita, Cynthia Astika, Ismiar Budiarti, Rery Cahyani, Nastiti Dwi Edward Kurnia Setiawan Limijadi, Edward Kurnia Setiawan Farah Hendara Ningrum Farokah, Farokah Handayani, Peny Hariyati, Riece Iriani, Desy Kanti Yunika, Kanti Karlowee, Vega Kristyanto, Jarod Wahyu Kusumaningrum, Lely Liemiyah, Rikha Marliyawati, Dwi Muhammad Yusuf Muyassaroh Muyassaroh Nugroho, Nur Iman Priambada, Dody Pujo Widodo, Pujo Rachma, Devi Elvina Ruspita, Dian Ayu Sabig, Lidya sayuti, fajri imam Septarina, Faiza Rizky Aryani Widodo , Pujo Willy Yusmawan, Willy Yanuar Iman Santosa Yunika, Kanthi Zulfikar Naftali, Zulfikar