Claim Missing Document
Check
Articles

Found 27 Documents
Search

Introduction to Bibliometric Studies for Lecturers of the Faculty of Health Sciences, Universitas Muhammadiyah Palangkaraya Mohammad Rizki Fadhil Pratama; Muhamad Riza Syah Fahlevi
Jurnal Pengabdian dan Pemberdayaan Masyarakat Indonesia Vol. 3 No. 7 (2023)
Publisher : Peneliti Teknologi Teknik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59247/jppmi.v3i7.134

Abstract

Bibliometric studies have become a new standard in finding gap research for further research. Mastering software such as VOSViewer can be beneficial in carrying out these bibliometric studies utilizing databases of international scientific publications. However, bibliometric research still needs to be discovered by some academics, especially those unfamiliar with it, such as lecturers at the Faculty of Health Sciences, Universitas Muhammadiyah Palangkaraya. Therefore, this service activity aims to introduce and train these lecturers regarding bibliometric studies using VOSviewer. The solution offered by the servant is to carry out introductory activities and training in operating VOSviewer in carrying out the bibliometric study. Apart from introducing the lecturers to the branch of science, which is currently in great demand worldwide, it also increases the enthusiasm for writing for the participants. Through the activities, the participants have carried out a bibliometric study in Pharmacy and Medical Laboratory Technology, which can then be published as a separate bibliometric study. As a follow-up to this activity, apart from being able to do it for lecturers in other faculties within the Universitas Muhammadiyah Palangkaraya, training is also planned to be carried out to publish scientific articles on the results of the bibliometric study.
Profil Penggunaan Obat Antihipertensi di RSUD Mas Amsyar Kasongan Kabupaten Katingan: A Profile of Antihypertensive Medicines in Mas Amsyar Hospital Kasongan Katingan Regency Syahrida Dian Ardhany; Wahyu Pandaran; Mohammad Rizki Fadhil Pratama
Borneo Journal of Pharmacy Vol. 1 No. 1 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i1.248

Abstract

Hypertension or high blood pressure is one of the lead causes of death. Hypertension can cause various complications with another disease, even the cause of heart disease, stroke, and kidney disorders. Hypertension is the second rank of the most diseases in Kabupaten Katingan. The purpose of this research is to know the profile of antihypertensive medicines in RSUD Mas Amsyar Kasongan. Method of this research was a descriptive method with saturation sampling used retrospective data on all prescription drugs in 2017. The results of this research based on the patient characteristic were found 43.3% men and 56.7% women, meanwhile 45.8% age < 45 years old and 54.2% for age > 45 years old. The antihypertensive drug items used are propranolol, telmisartan, amlodipine, lisinopril, furosemide, ramipril, valsartan, candesartan, irbesartan, and bisoprolol, meanwhile based on the classification of antihypertensive drugs. are angiotensin II receptor blockers (ARB), diuretics, angiotensin converting enzyme Inhibitors (ACEI), Calcium Channel Blockers (CCB) and alpha 2 adrenergic agonists. Based on the result, it can be concluded that hypertension patient in RSUD Mas Amsyar Kasongan is mostly female (56.7%) and age of hypertension patient is > 45 years old (54.2%). The most antihypertensive prescribed is monotherapy (72%) and the most item of the drug is amlodipine. (38%).
Profile of Thin-Layer Chromatography and UV-Vis Spectrophotometry of Akar Kuning Stem Extract (Arcangelisia flava) Mohammad Rizki Fadhil Pratama; Suratno Suratno; Evi Mulyani
Borneo Journal of Pharmacy Vol. 1 No. 2 (2018): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v1i2.367

Abstract

This study aims to obtain the profile of Thin-Layer Chromatography (TLC) and Ultraviolet-Visible (UV-Vis) spectrophotometry from the ethanol extract of akar kuning stems (Arcangelisia flava) from Central Kalimantan. The TLC method is used with the orientation phase of the combination of polar-non-polar solvents resulting from orientation, while ethanol is used as the solvent for UV-Vis spectrophotometers. TLC results showed the formation of three stains on a mixture of polar solvents chloroform : methanol : water while in a non-polar solvent combination n-hexane : ethyl acetate did not show any stains. Comparison of retention factor (Rf) values shows the best combination of polar solvents to separate stains at a ratio of 5 : 2 : 1, respectively. Separation in 2-dimensional TLC with polar solvents showed a similar pattern with 1-dimensional separation in the form of three stains. UV-Vis spectrophotometer results showed four main peaks with wavelength 227.2; 267.4; 345.2; and 425.3 nm, respectively. The profile of the peak formed is very similar to that shown by berberine, one of the primary metabolites of akar kuning. TLC and UV-Vis spectrophotometers profiles obtained are expected to support further research using akar kuning stems, especially those from Central Kalimantan.
In silico study of the essential oil compounds of ginger and thyme on Coronavirus-2 receptors Caroline Caroline; Martha Ervina; Muhammad Rizki Fadhil Pratama; Maria Anabella Jessica
Pharmaciana Vol 13, No 3 (2023): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v13i3.26964

Abstract

Coronavirus-2 (SARS-Cov-2) is a virus that attacks the respiratory system and causes the Covid-19 pandemic. After the pandemic, prevention and appropriate therapy research continue to be carried out to anticipate the emergence of more dangerous viruses. In line with the culture of consuming herbs that has arisen due to the effects of the pandemic, in this study, an insilico screening was carried out for essential oil compounds produced by ginger and thyme herbs which have been widely consumed by the public. The aim of the research was to find the essential oil content that has the most potential as an antiviral against coronavirus-2. The research method was carried out in silico, including ligand preparation, receptor and method validation, and analysis of ligand-receptor binding interactions using the AutoDoc 4.2.6 program. As a comparison, a study was conducted on remdesivir and favipiravir, which have been used as antivirals. The three components that have the most potential based on the calculation of the free energy value, were determined by the ADMET parameters using the Admet lab 2.0 program. The results showed that the three components in the essential oil exhibited better interactions when compared to remdesivir and favipiravir at the 3-Cl protease and spike glycoprotein receptors. The results of the insilico study and ADMET prediction test showed that of the three most potent compounds, lamda-farnesen was the most potent and safe to use
Improvement of Quality and Quantity of Technology-Based Learning in Pharmacy and Medical Laboratory Technology Chusna, Nurul; Novaryatiin, Susi; Purbayanti, Dwi; Mulyani, Evi; Ardina, Rinny; Rahmah, Windya Nazmatur; Pratama, Mohammad Rizki Fadhil
Borneo Journal of Medical Laboratory Technology Vol. 7 No. 2 (2025): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v7i2.7166

Abstract

The enhancement of technology-based learning in the fields of pharmacy and medical laboratory technology is imperative to keep pace with advancements in healthcare and educational methodologies. This study investigates the strategies and impacts of integrating cutting-edge technologies into the curricula of these disciplines. Key areas of focus include the implementation of virtual simulations, online learning platforms, and interactive multimedia resources. The research highlights how these technologies improve the quality of education by providing students with realistic, hands-on experiences that enhance their practical skills and theoretical knowledge. Additionally, the study explores the scalability and accessibility of technology-based learning, which contributes to increased student engagement and enrollment. By leveraging data analytics and feedback mechanisms, educators can tailor learning experiences to meet individual student needs, thereby improving learning outcomes. The findings suggest that the thoughtful integration of technology not only enriches the educational experience but also prepares students more effectively for the evolving demands of the healthcare industry. This research underscores the necessity of continuous investment in educational technologies to sustain the quality and quantity of learning in pharmacy and medical laboratory technology programs.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 8 No. 1 February 2025 Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy Vol. 8 No. 1 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i1.9637

Abstract

Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm), has been published at February 2025. This edition contains ten articles: Pharmaceutical Regulations, Pharmacology-Toxicology, Clinical-Community Pharmacy, Pharmacognosy-Phytochemistry, Analytical Pharmacy-Medicinal Chemistry, and Natural Product Development, and. This edition includes writings from three countries: Egypt, Indonesia, and Libya. The authors come from several institutions, including Indonesian Food and Drug Authority, Universitas Lambung Mangkurat, Universitas Borneo Lestari, Institut Teknologi Bandung Universitas Muhammadiyah Surabaya, Universitas Mahasaraswati Denpasar, Universitas Muhammadiyah Palangkaraya, Universitas Islam Indonesia, Sekolah Tinggi Ilmu Kesehatan Salsabila Serang, University of Tripoli, Egypt-Japan University of Science and Technology, El Ezaby Pharmacy, Universitas Ahmad Dahlan, IPB University, and Universitas Sriwijaya. Editorial boards are fully aware that there are still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors and reviewers, and contributors of the scientific articles who have provided the repetoire in this issue. We hope that all parties, especially the contributors, could re-participate for the publication in the next edition on May 2025. Wassalamu’alaikum Wr. Wb.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 8 No. 2 May 2025 Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy Vol. 8 No. 2 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i2.10305

Abstract

Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. The next edition of Borneo Journal of Pharmacy (Borneo J Pharm) has been published in May 2025. This edition contains ten articles: Pharmacology-Toxicology, Pharmaceutical, Analytical Pharmacy-Medicinal Chemistry, and Natural Product Development. This edition includes writings from two countries: Indonesia and Thailand. The authors come from several institutions, including Universitas Sari Mulia, Universitas Borneo Lestari, Universitas Ahmad Dahlan, Sekolah Tinggi Ilmu Kesehatan Samarinda, Universitas Alma Ata, Universitas Jambi, Universitas Bengkulu, Universitas Muhammadiyah Prof Dr Hamka, Institut Teknologi Bandung, Universitas Halu Oleo, Thammasat University, Universitas Jember, Universitas Airlangga, Universitas Anwar Medika, Universitas Muhammadiyah Kalimantan Timur, and Universitas Muhammadiyah A.R. Fachruddin. Editorial boards are fully aware that there is still room for improvement in this edition; hence, with all humility, we are willing to accept constructive suggestions and feedback for improvements to the publication for the next editions. The editorial board would like to thank all editors, reviewers, and contributors of the scientific articles who have provided the repertoire in this issue. We hope that all parties, especially the contributors, could re-participate in the publication in the next edition in August 2025. Wassalamu’alaikum Wr. Wb.
Cover, Content, and Editorial Note from Borneo J Pharm Vol. 8 No. 3 August 2025: From Borneo's Bounty to Global Insights: Embracing Natural Products and Computational Innovation in Pharmacy Borneo J Pharm, Chief Editor of
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.11058

Abstract

Assalamu’alaikum Wr. Wb. Alhamdulillahirabbil ‘alamin. The newest edition of Borneo Journal of Pharmacy (Borneo J Pharm) was published in August 2025. This edition contains ten articles: Pharmacology-Toxicology, Pharmacognosy-Phytochemistry, Analytical Pharmacy-Medicinal Chemistry, Microbiology Pharmacy, Natural Product Development, Clinical-Community Pharmacy, and Management Pharmacy. This edition includes writings from three countries: India, Indonesia, and Russia. The authors come from several institutions, including Universitas Pakuan, Universitas Surabaya, Universitas Airlangga, Universitas Sam Ratulangi, Universitas Muslim Indonesia, Uttaranchal University, Virtual Research Center for Bioinformatics and Biotechnology, Universitas Brawijaya, Ural State Agrarian University, Gorbatov Research Center for Food Systems, South Ural State Agrarian University, Yaroslav-the-Wise Novgorod State University, Universitas Islam Negeri Mataram, Universitas Ma Chung, National Research and Innovation Agency of the Republic of Indonesia, Universitas Mulia, Universitas Muhammadiyah Klaten, Rumah Sakit Umum Pusat Dr. Sardjito, Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin, Universitas Sari Mulia, and Universitas Muhammadiyah Yogyakarta. This collection of articles powerfully showcases the journal's commitment to advancing pharmaceutical science across three vital frontiers: natural products research, cutting-edge computational analysis, and health system optimization. The research presented here not only taps into the rich biodiversity of Indonesia, particularly the Borneo region and its cultural connections, but also leverages modern technology to accelerate drug discovery and enhance patient care. Harnessing Nature's Pharmacopoeia A significant portion of this issue is dedicated to the scientific validation of traditional remedies, highlighting the pharmacological promise of flora from the region and beyond. In a compelling in vivo study, the effect of javanese chili (Piper retrofractum) and lemon (Citrus limon) formula on total cholesterol levels in male white rats demonstrates the potential of optimizing herbal combinations. The research found that the two extracts' specific ratios (1:1 and 1:2) yielded substantial hypocholesterolemic effects, even superior to the positive control simvastatin. This reinforces the necessity of dosage and ratio optimization in herbal formulation. Further contributing to the natural products sphere, comparison of characteristics and antibacterial activity of mandai cempedak vinegar with variations in fermentation methods explores a traditional fermented food product from East Kalimantan. This work characterizes the potential probiotic lactic acid bacteria (LAB) from Mandai vinegar, providing a valuable foundation for its future development as a functional food ingredient. Rounding out this theme, two studies focus on the ubiquitous red ginger (Zingiber officinale var. rubrum). Comparison of chromatogram profiles of red ginger (Zingiber officinale var. rubrum Theilade) rhizome essential oil based on differences in growing places provides critical industrial insight, showing that geographic location significantly alters the vital oil composition—a finding crucial for standardization and quality control. Complementing this, the physicochemical profile and stability of red ginger (Zingiber officinale var. rubrum) SNEDDS as a potential aphrodisiac demonstrates that advanced delivery systems, specifically SNEDDS, can effectively enhance the stability of this valuable extract, paving the way for superior pharmaceutical products. Accelerating Drug Discovery with In Silico Power This issue strongly features the application of computational pharmacy, demonstrating how molecular docking and predictive modeling are revolutionizing the identification of new drug candidates: In silico analysis of the antigastritis activity of gedi (Abelmoschus manihot) flower flavonoids on H2 receptor identified quercetin as a key flavonoid in gedi flower with promising potential as an H2 antagonist for gastritis treatment; molecular docking analysis of flavonoids from Syzygium cumini (L.) Skeels: proapoptotic potential as an anticancer mechanism points to epigallocatechin 3-O-gallate and ellagic acid as potent anti-Non-Small Cell Lung Cancer (NSCLC) agents, targeting key apoptotic proteins; and molecular docking study of substituted benzamide derivatives as analgesic candidates employed computational screening to identify promising derivatives of N-allyl-N'-(benzoylcarbamothioyl)benzamide, generating a library of novel compounds that warrant further in vivo validation. These studies underscore the efficiency of in silico methods in prioritizing targets, saving resources, and guiding future laboratory investigations. They are further supported by discovery of novel alkaloids from Magnolia Genus: a literature review from 2002-2024. This comprehensive review consolidates the recent identification of novel bioactive alkaloids, providing a roadmap for natural product drug development. Advancing Clinical Pharmacy and Health Economics Beyond product development, the journal remains committed to applied research that improves healthcare delivery: balancing need and feasibility: stakeholder insights on frequent blood glucose monitoring in Indonesia provide a qualitative analysis of the barriers (e.g., irregular patient visits, negative emotions) and facilitators (e.g., active role of pharmacists, free NHI testing) to essential blood glucose and HbA1c monitoring. This research is crucial for developing targeted strategies to ensure medication effectiveness and patient safety in primary care settings, and finally, the cost analysis of inpatient stroke treatment at PKU Muhammadiyah Yogyakarta Hospital based on INA-CBG's tariff in 2023 delves into health economics, analyzing the financial feasibility of stroke management under the updated INA-CBG's reimbursement system. Such studies are vital for ensuring hospital sustainability and effective resource allocation within the national health insurance framework. Collectively, this issue presents a vibrant mosaic of pharmaceutical research—from traditional phytochemistry and modern nanodelivery to computational screening and health policy analysis. We hope this diverse findings will inspire further collaboration between academic research, industry, and clinical practice, ultimately translating knowledge into better health outcomes. Editorial boards are fully aware that there is still room for improvement in this edition; hence, with all humility, we are willing to accept constructive suggestions and feedback for improvements to the publication for the subsequent editions. The editorial board would like to thank all editors, reviewers, and contributors to the scientific articles who have provided the repertoire for this issue. We hope that all parties, especially the contributors, could re-participate in the publication in the next edition in November 2025. Wassalamu’alaikum Wr. Wb.
Molecular Docking Study of Akar Kuning (Arcangelisia flava) Secondary Metabolites as Src Inhibitor Pratama, Mohammad Rizki Fadhil; Mulyani, Evi; Suratno, Suratno
Indonesian Journal of Cancer Chemoprevention Vol 10, No 3 (2019)
Publisher : Indonesian Society for Cancer Chemoprevention

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14499/indonesianjcanchemoprev10iss3pp122-130

Abstract

Proto-oncogene tyrosine-protein kinase Src is also known as simply Src is a tyrosine kinase protein which is one of the targets in various cancer therapies such as leukemia. Meanwhile, akar kuning (Arcangelisia flava) has gained significant attention as a medicinal plant that has a cytotoxic effect on various types of cancer cells. This study aims to determine the potential of secondary metabolites of akar kuning as Src inhibitors. Molecular docking was carried out using Autodock Vina 1.1.2 with 2HCK receptors, that quercetin and dasatinib were used as reference ligands. The docking results showed that the highest affinity was shown by berberine with a ΔG value of -9.0 kcal/mol, exceeded quercetin and dasatinib. However, the highest amino acid similarity to quercetin and dasatinib was produced by jatrorrhizine, with 93.33% and 73.91%, respectively. Interestingly, berberine is the ligand with the third-highest similarity after jatrorrhizine and palmatine, while jatrorrhizine has the second-highest affinity after berberine. The results concluded that the combination of berberine and jatrorrhizine is predicted to be optimally used as an Src inhibitor in cancer therapy.
Rambusa (Passiflora foetida L) vs. Free Radicals: In Vitro Study with DPPH Method Dewi Sari Mulia; Evi Mulyani; Muhammad Ikhwan Rizki; Mohammad Rizki Fadhil Pratama
Journal of Pharmascience Vol. 6 No. 2 (2019): Jurnal Pharmascience
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7344

Abstract

ABSTRAK             Rambusa (Passiflora foetida L) adalah tumbuhan obat yang banyak terdapat di berbagai daerah di Indonesia, termasuk di Kalimantan Tengah. Beberapa bagian tumbuhan dari rambusa diketahui memiliki aktivitas antioksidan termasuk di bagian daunnya. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari daun rambusa yang berasal dari Kalimantan Tengah. Metode yang digunakan adalah metode 2,2-diphenyl-1-picrylhydrazyl (DPPH) yang diukur serapannya dengan Spektrofotometer UV Vis. Hasil yang diperoleh menunjukkan nilai IC50 dari ekstrak etanol daun rambusa senilai 93,269 μg/mL. Meskipun nilai IC50 yang diperoleh lebih rendah dibandingkan senyawa antioksidan standar seperti kuersetin, nilai IC50 dari ekstrak etanol daun rambusa asal Kalimantan Tengah masih lebih tinggi dibandingkan daun rambusa yang diperoleh dari daerah lain Kata Kunci—antioksidan, DPPH, Kalimantan Tengah, Passiflora foetida, rambusa  ABSTRACT Rambusa (Passiflora foetida L) is a medicinal plant that is widely found in various regions in Indonesia, including in Central Kalimantan. Some parts of the plant of rambusa are known to have antioxidant activities including in the leaves. This study aims to determine the antioxidant activity of rambusa leaves from Central Kalimantan. The method used was 2,2-diphenyl-1-picrylhydrazyl (DPPH) method which was measured by UV Vis spectrophotometer. The results obtained showed IC50 values of ethanol extract of rambusa leaves worth 93.269 μg/mL. Although the IC50 values obtained were lower than the standard antioxidant compounds such as quercetin, the IC50 value of the ethanol extract of the leaves of rambusa from Central Kalimantan was still higher than that of the rambusa leaves obtained from other regions or some other medicinal plant extracts. Keywords— antioxidants, DPPH, Central Kalimantan, Passiflora foetida, rambusa