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ANALISIS EFEKTIVITAS BIAYA KEMOTERAPI PADA PASIEN KANKER PAYUDARA DI RSPAD GATOT SOEBROTO JAKARTA Musnelina, Lili; Pontoan, Jenny; Martin, Clara Jesica
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (88.649 KB)

Abstract

Breast cancer is a disease of malignant neoplasm which is an abnormal growth of tissue that is different from the surrounding tissue. Various used of chemotherapy in the process of achieving management in cancer that causes the use of benefits and costs. This study aims to determine a more effective therapy in breast cancer patients at RSPAD Gatot Soebroto in 2017. This study was non experimental with comparative study into two group chemotherapy is single group (chemotherapy bondronat) and combination group (chemotherapy doxorubicin-paclitaxel). This study use secondary data from medical records patients on retrospectively. The results showed a decrease in the scale of single chemotherapy (Bondronat) was 82,61% with an average direct medical cost of IDR 9,3 million where as in combination chemotherapy (Doxorubicin-Paclitaxel) 95,65% with an average direct medical cost of IDR 7,6 million. The ACER value in single chemotherapy was IDR 11,3 million and combination chemotherapy was IDR 7,9 million. The ICER value in the two treatment groups was IDR 13,5 million. The conclusion is the combination of chemotherapy of Doxorubicin-Paclitaxel is the most cost-effective than Bondronate single chemotherapy.
TINGKAT KEPUASAN PASIEN RAWAT JALAN TERHADAP PELAYANAN KEFARMASIAN DI INSTALASI FARMASI RUMAH SAKIT MARINIR CILANDAK JAKARTA Pontoan, Jenny; Meila, Okpri; Asnanik, Yuli; Muharam, Muhammad Azhar
Jurnal Ilmiah Manuntung Vol 6 No 1 (2020): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung akademi farmasi samarinda

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Abstract

Measuring the quality dimensions of health service is essential and should be done along with patient satisfaction surveys. The level of patient satisfaction with hospital health services may use the five-dimensional Service Quality (ServQual) method, that is, reliability, responsiveness, assurance, concern and tangible form. The study was conducted to determine the level of outpatient satisfaction with the quality of services provided by The Cilandak Marinir Hospital Pharmacy Installation. The research design is Observational by survey methods, conducted on JKN outpatients, with a total sample of 106 respondents. Inclusion criteria; patients who redeem a prescription at a hospital pharmacy installation at least 2 times; patients who are willing to fill out the questionnaire, sign the questionnaire, and approve the informed consent; patients aged ? 15 years. Exclusion criteria are patients who are hospital employees; HIV / AIDS patients. This study was also complemented with data collection permits from the hospital and ethical approval from the ethics research committee of the Universitas Pembangunan Veteran Jakarta. The instrument used is in the form of a questionnaire to measure patient satisfaction about pharmacy services at the pharmacy. The results of the validity test of 0.383-0.950 (components of expectations) and 0.362-0.928 (components of performance) are declared valid. The reliability test results are 0.954-0.961 (expectation component) and 0.951-0.960 (performance component); these results indicate that the questionnaire can be used because all questions are reliable (> 0.60 Cronbach Alpha scores). Data analysis uses the Service Quality method (Service Quality score = Performance - Expectation). A positive score indicates that customer expectations are met so that services on specific dimensions can be perceived as high quality and vice versa. Ideally, the value of the gap between expectations and perceptions is zero. ServQual analysis results based on the gap showed that the most significant value of the gap in the dimensions of reliability -0.18, responsiveness (responsiveness) -0.12, awareness (empathy) -0.08, assurance -0, 07, and tangible form (tangible) -0.03. Based on these results, It can be concluded that pharmaceutical services still need improvement because they still have a negative gap value for the five dimensions.  
Analisis Tingkat Kepuasan Pasien BPJS Pada Pelayanan Kefarmasian Di Apotek Klinik SATKES PUSDOKKES MABES POLRI Meila, Okpri; Pontoan, Jenny; Zizwanto, , Eddy
Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Vol 1 No 02 (2020): HERCLIPS VOL 01 NO 02
Publisher : Universitas Muhammadiyah Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30587/herclips.v1i02.1520

Abstract

Service satisfaction is achieved if what the patient gets exceeds what is expected. This study to determine the level of BPJS patient satisfaction and dimensions affect the level of satisfaction with pharmaceutical services provided in Drugstore Clinic Satkes Pusdokkes Headquarter Police. This reasearch was conducted the data of patients who were treated and carried out in cross sectional, by distribution questioner and analyzed descriptive. Reasearch subjects were teken by quota sampling technique. The level of satisfaction of this study was measured based on five dimensions of service quality and analyzed using percentase and likert scalet. The results of the showed that patients who were treated at the Drugstore Clinic Satkes Pusdokkes Headquarter Police were satisfied with the services provided by the services provided Keyword : Satisfaction level, pharmaceutical services, BPJS
ANALISIS EFEKTIVITAS TERAPI ANTIRETROVIRAL PADA PASIEN HIV/AIDS RAWAT JALANDI RSUP FATMAWATI JAKARTA TAHUN 2016 Yusi Anggriani; Alfina Rianti; Jenny Pontoan; Yulwa Juwita
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 4 No 1 (2019): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (229.813 KB) | DOI: 10.36387/jiis.v4i1.212

Abstract

The increasing of HIV/AIDS every year become a health problem in Indonesia. Patients of HIV/AIDS should use longterm Antiretroviral (ARV) therapy of antiretroviral therapy to support the success of antiretroviral therapy. The objective of this study was to know and compare the effectivity of four ARV combination. The four ARV combination are combination A (AZT+3TC+NVP), combination B (AZT+3TC+EFV), combination C (TNF+3TC+NVP), combination D (TNF+3TC+EFV) base on increasing CD4. This study cohort-longitudinal design. Samples for this study were taken by total sampling using all data of HIV/AIDS outpatients at RS Fartmawati on 2016. The inclusion criteria were patients of (≥17 years old), received treatment of either one of the four ARV combination, and had data of CD4 from laboratory result before and 6-12 months after the treatment. Data were taken from patients medical record and analyzed with non-parametric Kruskal Wallis-test. The study results showed of 124 patients had increased the CD4 mean >100 sel/mm3 one year after the treatment. The average rate of increment of each combination of antiretroviral therapy on a median CD4 cell count of 1 year was a combination of A (73.93), combination B (70.87), combination C (48.73), combination D (55.57) and there was a significant difference in CD4 cell gain in patients taking combination A-C (p value = 0.047), combination A-D (p value = 0.041), and combination B-D (p value = 0.045) at the evaluation on 1 year. Conclusion, combination A is more effective than combination B, D and C.
Evaluasi Waktu Tunggu Pelayanan Obat di Instalasi Farmasi Rawat Jalan RS X Okpri Meila; Jenny Pontoan; Didi Nurhadi Illian
SAINSTECH FARMA Vol 13 No 1 (2020): Sainstech Farma: Jurnal Ilmu Kefarmasian
Publisher : FAKULTAS FARMASI, INSTITUT SAINS DAN TEKNOLOGI NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (167.93 KB) | DOI: 10.37277/sfj.v13i1.522

Abstract

Standar waktu tunggu yang ditentukan pemerintah melalui Standar Pelayanan Minimal rumah sakit yaitu, pelayanan resep obat non racikan adalah ≤ 30 menit dan obat racikan adalah ≤ 60 menit. Pada pelayanan farmasi di rumah sakit, waktu tunggu adalah waktu yang dibutuhkan untuk menyelesaikan satu proses pelayanan mulai dari penerimaan resep sampai penyerahan obat. Pada jam 11.00 sd 14.00 merupakan jam sibuk di RS X, sehingga pada jam tersebut resep-resep masuk secara bersamaan sehingga terjadi penumpukan resep (delay). Hal ini tentu saja akan berdampak pada rendahnya kepuasan pasien rawat jalan terhadap kualitas pelayanan Depo Rawat Jalan. Maka perlunya mengevaluasi waktu tunggu untuk resep racikan dan non racikan pada Depo Rawat Jalan dan Pelayanan Swasta sehingga aktivitas-aktivitas yang memakan waktu lama pada proses pelayanan resep dapat diketahui. Penelitian dilakukan secara observasional dengan pengambilan data secara prospektif di depo rawat jalan dan pelayanan swasta, evaluasi lama waktu tunggu pelayanan obat dilakukan dengan menuliskan waktu saat pasien menyerahkan resep hingga pasien menerima obat di depo rawat jalan dan pelayanan swasta RS X. Berdasarkan hasil evaluasi waktu tunggu pelayanan obat di depo rawat jalan diketahui waktu tunggu pelayanan obat racikan di depo rawat jalan adalah selama 43 menit 8 detik, dimana ini belum memenuhi standar minimal pelayanan rumah sakit. Sedangkan waktu tunggu pelayanan obat racikan dan non racikan di Pelayanan Swasta adalah selama 13 menit 7 detik dan 32 menit 42 detik, dimana ini telah memenuhi standar minimal pelayanan rumah sakit.
Trend Price Analysis of Drug Before and After the Implementation of E-catalogue at the Hospital Yusi Anggriani; Prih Sarnianto; Siti Aisyah; Jenny Pontoan
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 9, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.594 KB) | DOI: 10.22146/jmpf.44496

Abstract

In 2013, Ministry of Health, Republic of Indonesia, launched a new change to drug procurement system, namely e-catalogue, to ensure the availability and affordability of medicines. This system replaces the previous auction drug procurement system. The purpose of the change into e-catalogue system is to facilitate the drug procurement in hospitals without the need to conduct complex negotiation with producers, to reduce the occurrence of mark-ups or inflating drug prices, to equalize drug prices, to support BPJS (Badan Penyelenggara Jaminan Sosial) activities, and to prevent difficulties in drug distribution in all regions in Indonesia. This study aims to get an overview and magnitude of the impact of e-catalogue application on changes in the price of drugs registered and not registered in e-catalogue at Jakarta Islamic Hospital Cempaka Putih. This research is a longitudinal time series study. The data collection was conducted retrospectively in the period of 2011-2015 taken from procurement data, purchase invoices, and e-catalogue prices from hospital pharmacy installation, which were then categorized based on similar drugs in the hospital. The result shows a decrease in the price of drugs on both e-catalogue drugs (generic, trade names and patents) and non e-catalogue drugs (generic, trade names). On the class of therapy, the biggest price reduction occurred in e-catalogue medicine, such as in antineoplastics, intravenous solution, diabetes, Anti-ashma & COPD, and psycholeptics therapy. Meanwhile, on the category of non e-catalogue, price reduction occurred in systemic antibacterials, antineoplastics, analgesics, cardiac theraphy, and A-acis A-flat A Ulcerants therapy. The magnitude of drug prices reduction ranges from 1% to more than 90% both on e-catalogue drugs and non e-catalogue drugs. On the e-catalogue drugs, the highest price reduction (82.36%) occurred in generic and patent drugs, while on non e-catalogue drugs, reduction occurred in drugs with trade names. The price reduction trend in drug prices based on both type of drugs and therapy class shows a significant decrease in drug prices in the period after the implementation of e-catalogue at Jakarta Islamic Hospital in Cempaka Putih, with a decrease of more than 80%.
Relationship between Dose and Retention of Methadon Maintenance Therapy to Drug Dependence Patients in Primary Health Care Lili Musnelina; Jenny Pontoan; Bagus Atmana Prasetya
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.57922

Abstract

Methadon maintenance therapy is one of the substitution therapies needed as an approach to harm reduction or the reduction of the adverse effects of drug abuse. This study aims to fix the infinitive relationship doses with retention of drug dependence patients on methadon maintenance therapies program (PTRM) in Kramat Jati Primary Health Care in 2009-2018. A cross-sectional study is conducted using secondary data from medical records subsequently significance analysis. This research involves 136 patients who were included in the inclusion criteria. Results shown mean initial doses received is 27,65 mg (10-40 mg), after 2 weeks of therapy mean doses received are 51,6 mg (range 22,5 – 85 mg). Average lowest and highest maintenance dose which received is 30,9 mg (range 0,25-115 mg) dan 84,39 mg (range 7,77-126,92 mg). This research shows the retention value 1 year or more reaches 64,71%. Maintenance doses 2 weeks (P=0,005), lowest maintenance doses (P=0,000), average maintenance doses (P=0,004), and history misses doses (P=0,000) have significance with retention. The conclusion that the more optimal maintenance doses received, even more in methadone maintenance therapies. Otherwise, lower missed doses frequency better to patients retention in methadon maintenance therapies.
Persepsi Pasien dengan Keluhan Minor Illness terhadap Peran Apoteker Terkait Efisiensi Biaya dan Akses Pengobatan di Era Jaminan Kesehatan Nasional Irmin Irmin; Prih Sarnianto; Yusi Anggriani; Jenny Pontoan
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 17 No. 01 Juli 2020
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pharmacy.v17i1.5622

Abstract

Minor Illness adalah kondisi medis yang kurang serius yang tidak memerlukan tes laboratorium atau tes darah. Minor illness juga didefinisikan sebagai kondisi yang akan hilang dengan sendirinya dan dapat sembuh dengan melakukan pengobatan sendiri (swamedikasi). Kebanyakan pasien dapat mengobati penyakit minor illness hanya dengan menggunakan obat-obat OTC (Over-the-Counter). Penelitian ini bertujuan untuk mengetahui persepsi pasien dengan keluhan minor illness terhadap peran apoteker terkait efisiensi biaya obat dan akses pengobatan di era JKN (Jaminan Kesehatan Nasional). Penelitian ini dapat memberikan masukan bagi pemerintah dalam hal ini BPJS (Badan Penyelenggara Jaminan Sosial) sebagai otoritas pelaksana program JKN terkait pentingnya peran apoteker dalam melakukan efisiensi biaya dan kemudahan akses pengobatan pasien dengan keluhan penyakit minor illness. Penelitian ini menggunakan metode observasi dengan pengolahan data secara deskriptif. Penelitian ini dilakukan di apotek yang bekerjasama dengan BPJS di wilayah DKI, dengan sampel sebanyak 99 responden pasien yang melakukan swamedikasi pada bulan Juni 2018. Hasil penelitian menunjukkan bahwa terdapat potensi efisiensi biaya baik dari aspek manajemen, klinis, swamedikasi yang efektif dan terdapat kemudahan akses pengobatan melalui swamedikasi. Kesimpulan, keterlibatan apoteker dalam menangani keluhan minor illness terbukti menghemat biaya dan kemudahan akses pengobatan.
UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA DARI EKSTRAK DAUN ALPUKAT (Persea americana M.) Jenny Pontoan
INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL Vol 1, No 1 (2016)
Publisher : Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (392.37 KB) | DOI: 10.52447/inspj.v1i1.241

Abstract

ABSTRAK Tabir surya merupakan sediaan kosmetika yang digunakan dengan maksud melindungi kulit dari paparan sinar matahari dengan jalan memantulkan atau menyerap sinar matahari secara efektif terutama pada daerah emisi gelombang ultraviolet, sehingga dapat mencegah terjadinya gangguan kulit karena terpapar sinar matahari. Bahan aktif tabir surya yang digunakan dapat berupa senyawa sintetik ataupun senyawa yang berasal dari alam. Penelitian dilakukan untuk menentukan aktivias ekstrak daun alpukat (Persea americana M.) sebagai tabir surya secara in vitro dan menguji aktivitas krim ekstrak daun alpukat (Persea americana M.) sebagai tabir surya secara in vivo. Penelitian ini menggunakan metode eksperimen laboratorium. Hasil penelitian menunjukkan bahwa daun alpukat memiliki kandungan metabolit sekunder yaitu alkaloid, flavonoid dan saponin. Ekstraksi menggunakan tiga pelarut yaitu metanol, etanol dan aseton menghasilkan rendemen terbesar pada pelarut metanol (22,54). Kandungan total fenolik tertinggi pada pelarut aseton (71,32), flavonoid tertinggi pada pelarut etanol (6,63), uji aktivitas antioksidan (DPPH dan daya reduksi) tertinggi pada pelarut aseton sedangkan nilai SPF tertinggi pada pelarut etanol (14,45).   Kata Kunci : Daun Alpukat (Persea americana M.), Antioksidan, Tabir Surya, SPF ABSTRACT Sunscreen is cosmetics preparation used for protecting skin from sunburn exposure by means of reflecting or absorbing sunlight effectively, particularly in the area of ultraviolet wave emission so that it can prevent the occurence of skin disorder due to the exposure of sunlight. The used sunscreen active material can be in the form of synthetic compound or compound deriving from the nature. The study is conducted by determining the activity avocado leaves extract (Persea americana M.)as sunscreen through in vitroandtest the activity of avocado leaves extract cream (Persea americana M.)as sunscreen through in vivo.This study utilizes laboratory experiment method. The result of the study shows that avocado leaves have secondary metabolite contents such as alkaloid, flavonoid and saponin. Extraction uses three solvents such as methanol, ethanol and acetoneresulting the biggest yield in methanol solvent (22,54). The highest phenolic total content is on acetone solvent (71,32), the highest flavonoid on ethanol solvent (6,63), the highest antioxidant activity test (DPPH and reduction power) on acetone solvent, whereas the highest SPF is on ethanol solvent (14,45).   Keyword:        Avocado leaves (Persea americana M.),Antioxidant, Sunscreen, SPF
FORMULASI GEL ANTISEPTIK TANGAN EKSTRAK ETANOL 70% RIMPANG LEMPUYANG WANGI (Zingiberis aromaticum Val.) DENGAN BASIS HYDROXY PROPYL METHYL CELLULOSE (HPMC) TERHADAP BAKTERI Staphylococus aureus Jenny Pontoan
INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL Vol 1, No 2 (2016): Indonesia Natural Research Pharmaceutical Journal
Publisher : Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.014 KB) | DOI: 10.52447/inspj.v1i2.832

Abstract

ABSTRAK Ekstrak kental etanol 70% rimpang lempuyang wangi (Zingiberis aromaticum Val) memiliki daya aktivitas antibakteri, baik gram positif maupun negatif, sehingga dapat dibuat sediaan semi padat yaitu gel antiseptik tangan. Tujuan penelitian ini untuk mengetahui formulasi sediaan gel antiseptik tangan yang mengandung ekstrak kental rimpang lempuyang wangi dengan menggunakan HPMC dengan konsentrasi berbeda yang dibuat dalam 5 formulasi yaitu 2,5%, 2,5%,5%, 7,5%, dan 10% masing-masing diformulasikan dengan ekstrak 20%. Uji aktivitas antibakteri menggunakan metode sumuran dengan menggunakan bakteri Staphylococcus aureus dengan menggunakan media Natrium Agar.Evaluasi gel yang dilakukan meliputi stabilitas ruangan suhu kamar 25°C selama 30 hari penyimpanan. Basis yang memiliki karakteristik terbaik adalah 2,5% dibanding formula lain. Sediaan gel antiseptik yang mengandung ekstrak kental rimpang lempuyang wangi yang menunjukkan adanya perbedaan aktivitas antiseptik adalah 2,5%(F1) dan 5%(F2) terhadap 10%(F4) dengan nilai sig P<0,05%. Uji data untuk menghitung zona hambat dengan menggunakan uji statistik Anova satu arah dengan nilai kepercayaan95%. Kata Kunci : gel, hand sanitizer, Zingiberis aromaticum Val, Staphylococcus aureus. ABSTRACT Extract spissum ethanol 70% rimpang lempuyang wangi (Zingiberis aromaticum Val) have power antibacterial activity, both gram positive and negative, that can be made of semi-solid preparations, namely antiseptic hand gel. The purpose of this study to determine the antiseptic hand gel formulation containing a extract spissum lempuyang wangi by using HPMC with different concentrations were made in five formulations of 2.5 %, 2.5%, 5 %, 7.5 %, and 10 % each formulated with 20%. Antibacterial activity test using wells with bacteria Staphylococcus aureus using Sodium media Agar. Evaluation gel was conducted on the stability of the indoor room temperature of 25 ° C for 30 days  of storage. A base that has the best characteristic was 2.5% compared to other formulas. Antiseptic gel formulation containing a extract spissum of lempuyang wangi indicated differences antiseptic activity was 2.5 % ( F1 ) and 5 % ( F2 ) to 10 % ( F4 ) with sig P < 0,5% . Test data to calculate inhibition zone using one way Anova statistical test with a value of 95% . Keywords: Gel, Hand sanitizer, Antiseptic, Zingiberis aromaticum Val, Staphylococcus aureus