ABSTRACT Anemia is a health problem that plays a role in causing high maternal and infant mortality rates. Anemia that occurs in pregnant women due to lack of iron intake during pregnancy. The number of pregnant women with anemia in Lampung Province in 2021 is 21.2% and the Mulyojati Health Center the number of pregnant women with anemia is 11.54% while the marketing of FE tablets is 9.7% because pregnant women do not comply with control during ANC. This study aims to determine the factors that associated with the incidence of anemia in third trimester pregnant women at the Mulyojati Health Center Metro City.This type of quantitative research with a cross sectional approach. The population of the study was pregnant women at the Mulyoajati Health Center using a total sampling technique. The research sample is 110 respondents. The research instrument is a questionnaire. Data analysis used for univariate analysis of frequency distribution, bivariate analysis using chi square test and multivariate analysis using multiple logistic regression. The results showed that respondents with age were not at risk (71.8%), not working (51.8%), parity was not at risk (52.7%), family support was supportive (57.3%), health worker support was less supportive (51.8%), ANC examination according to the standard (6 times) (53.6%), Fe tablet compliance was compliant (60.9%), the incidence of anemia (30.9%) pvalue variable age (p=0, 379 OR 1.636), occupation (p=0.437 OR 1.506), parity (p=0.067 OR 2.345), family support (p=0.038 OR 2.593), health worker support (p=0.044 OR 2.583), ANC examination (p=0.018 OR 2.971), Fe tablet adherence (p=0.002 OR 3.965) the most dominant factor associated is the Fe table adherence variable exp (B) value 3.416. This research is expected that health workers communicate continuously in the form of providing information on anemia in pregnant women, for visitors it is expected to build a smart attitude to prevent anemia during pregnancy and further researchers are expected to examine the intervention method of strategic communication approach on the purpose of changing the attitude of preventing anemia in pregnant women. Keywords: Anemia, Pregnant Women, 3rd Trimester ABSTRAK Anemia merupakan masalah kesehatan yang berperan dalam penyebab tingginya angka kematian ibu dan angka kematian bayi. Anemia yang terjadi pada ibu hamil dikarenakan kurangnya asupan zat besi selama kehamilan. Provinsi Lampung ibu hamil dengan anemia pada tahun 2021 sebesar 21,2% dan Puskesmas Mulyojati jumlah ibu hamil dengan anemia sebesar 11,54% sedangkan pencapaian pemberian tablet FE sebesar 9,7 % dikarenakan ibu hamil tidak patuh kontrol saat ANC. Tujuan penelitian ini yaitu mengetahui faktor yang berhubungan dengan kejadian anemia pada ibu hamil trimester III di Puskesmas Mulyojati Kota Metro. Jenis penelitian kuantitatif dengan pendekatan Cross Sectional. Populasi penelitian ibu hamil Puskesmas Mulyoajati dengan teknik total sampling. Sampel penelitian 110 responden. Instrumen penelitian adalah kuesioner. Analisa data yang digunakan untuk analisa univariat distribusi frekuensi, analisa bivariat menggunakan uji Chi Square dan analisa multivariat menggunakan regressi logistic ganda. Hasil penelitian didapatkan responden dengan usia tidak beresiko (71,8%), tidak bekerja (51,8%), paritas tidak beresiko (52,7%), dukungan keluarga mendukung (57,3%), dukungan tenaga kesehatan kurang mendukung (51,8%), pemeriksaan ANC sesuai standar (6 kali) (53,6%), kepatuhan tablet Fe patuh (60,9%), kejadian anemia (30,9%) pvalue variabel usia (p=0,379 OR 1,636), pekerjaan (p=0,437 OR 1,506), paritas (p=0,067 OR 2,345), dukungan keluarga (p=0,038 OR 2,593), dukungan tenaga kesehatan (p=0,044 OR 2,583), pemeriksaan ANC (p=0,018 OR 2,971), kepatuhan tablet Fe(p=0,002 OR3,965) faktor yang paling dominan berhubungan adalah variabel kepatuhan tablet Fe nilai exp (B) 3,416.Penelitian ini diharapkan tenaga kesehatan berkomunikasi yang berkelanjutan berupa pemberian informasi anemia ibu hamil, bagi pengunjung diharapkan membangun sikap cerdas mencegah anemia saat kehamilan dan peneliti selanjutnya diharapkan dapat meneliti dengan metode intervensi pendekatan komunikasi strategis pada tujuan perubahan sikap pencegahan anemia ibu hamil. Kata Kunci: Anemia, Ibu Hamil, Kepatuhan Tablet Fe, Trimester 3