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All Journal International Journal of Public Health Science (IJPHS) Medical Journal of Indonesia Health Notions Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Medica Arteriana (Med-Art) Majalah Biomorfologi (Biomorphology Journal) Cardiovascular and Cardiometabolic Journal (CCJ) CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Journal of Global Pharma Technology Jurnal Penyakit Dalam Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD) Folia Medica Indonesiana
Soelistijo, Soebagijo Adi
Departemen Ilmu Penyakit Dalam RSUD Dr. Soetomo – Fakultas Kedokteran Universitas Airlangga, Surabaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Pregnancy Following Recent Radioactive Iodine Ablation in Thyroid Cancer Patient A Case Report Robert Dwitama Adiwinoto; Soebagijo Adi Soelistijo; Hermina Novida; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.7

Abstract

Well-differentiated thyroid carcinoma (DTC) is common among females of reproductive age. Pregnancy is associated with hormonal (TSH and HCG) and metabolic changes that might affect the thyroid gland. Informationregarding the outcome of babies born to mothers who have recently undergone radioactive Iodine-131 ablation (RAI) is scarce. A 24-year-old pregnant woman with a history of thyroid cancer was consulted by the obstetrics and gynecology for further evaluation. She complained of a lump under the left jaw, and a thyroid nodule was found from further examination. Postoperative pathology of the right thyroid tissue revealed follicular and solid variant papillary thyroid carcinoma. Postoperative Thyroglobulin (Tg) level before ablation was 16.14 ng/mL. Ablation with Iodine-131 of 100 mCi was performed. Whole-body scintigraphy (WBS) indicated remaining functional thyroid tissue in the right thyroid field and thyroid tissue metastases in the left supraclavicular area. The patient waspregnant 3 months after the radioablation. Fetomaternal examination results 6 months pregnancy revealed fetal biometry according to gestational age (31 – 32 weeks) with an estimated fetal weight of 1787 grams and fetal doppler was normal. The patient is treated with levothyroxine 125 μ g once daily, folic acid 400 μ g twice daily, calcium lactate twice daily, and aspirin 80 mg once daily. The TSH level was 0.01 (0.55 – 4.78) μ IU/mL and the fT4 was 1.14 (0.7 – 1.48) ng/dL. The latest thyroid ultrasound indicated no discrete mass in the thyroid fossa and non-specific lymphadenopathies. The baby was born normally, weighed 2680 grams, with normal thyroid function tests (neonatal TSH 1.02 μ IU/mL, fT4 2.6 ng/dL).
Challenges in the Diagnosis and Management of Adrenal Insufficiency Febri Kurniawati; Sony Wibisono Mudjanarko; Soebagijo Adi Soelistijo; Agung Pranoto
‎ InaJEMD - Indonesian Journal of Endocrinology Metabolic and Diabetes Vol. 1 No. 1 (2024): InaJEMD Vol. 1, No. 1
Publisher : PP PERKENI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.66266/inajemd.v1i1.9

Abstract

Adrenal insufficiency (AI) is a rare endocrine condition. Primary adrenocortical insufficiency, or Addison diseases reduces the production of crucial hormones, including glucocorticoids, mineralocorticoids, and adrenal androgens. Due to the lack of proper cortisol response in adrenal crisis, it can be life-threatening during times of stress, emphasizing the need for a timely diagnosis. Despite this, diagnosing and managing AI still presents significant challenges. We report the case of a middle-aged woman who presented with complaints of weight loss, abdominalpain, lethargy, hyperpigmentation of the skin and mucosa, and a history of repeated hospitalizations for nausea, vomiting, dehydration, and hypovolemia. During the patient's previous hospitalization, Addison's crisis was suspected, and methylprednisolone therapy was administered, rendering the cortisol and ACTH assays inaccurate. The patient's condition subsequently improved. The subsequent monitoring revealed low cortisol levels, but an ACTH stimulation test was unavailable. The presence of pulmonary tuberculosis was indicated by a positive chest X-ray and IFN-Gamma Release Assay (IGRA) test. With a history of repeated hospitalizations, suspected Addison's crisis, hypoglycemia, mineralocorticoid involvement (hypotension, hyponatremia), and the presence of hyperpigmentation, a clinical diagnosis of primary adrenal insufficiency was made with limited conditions and testing tools. The patient was given anti-tuberculosis treatment and the lowest dose of hydrocortisone required to control the disease without causing side effects.
Co-Authors Adhibagio, Aria Damarjiwo Agung Dwi Wahyu Widodo Agung Pranoto AGUNG PRANOTO Alhakiim, Muhammad Valeri Amatlulloh, Hasna Shahida Ardiany, Deasy Ari Sutjahjo, Ari Ariana, Audy Meutia Artaria Tjempakasari, Artaria Audy Meutia Ariana Bambang Purwanto Batari Retno Minanti Chabib Fachry Albab Chandra Adi Irawan Primasatya Dewi Ratna Sari Dwitama Adiwinoto, Robert Fajar Setiyawan Febri Kurniawati Febrianto, Dicky Hadisuwarno, Wiharjo Hafizha Firdaus Al-Fuady Haikal, Vikri Hakim, Arief Rakhman Hasna Shahida Amatlulloh Hendra Gunawan Hermina Novida, Hermina Jayawarsa, A.A. Ketut Jihan Jauza Fairuz Jongky Hendro Prajitno Jusak Nugraha Lefi, Achmad Lenny Octavia Lusida, Michael Austin Pradipta Lutfi Dewanda Nugroho Lutfi, Delfitri Muhammad Miftahussurur Muhammad Valeri Alhakiim Nadhya Allia Nurainy Trias Setyoputri Poernomo Boedi Setiawan Prabowo, Gwenny Ichsan Pradhevi, Lukita Prasmono, Agung Prastyani, Reni Primasatya, Chandra Adi Irawan Puspa Putri, Karina Widya Rejeki, Purwo Sri Robert Dwitama Adiwinoto Ronald Pratama Adiwinoto Saefudin, Rendra Prasetya Sasono, Wimbo Sony Wibisono Thamrin, Husin Titong Sugihartono Ummi Maimunah Vincent, Agustinus Wulansari, Ratih