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All Journal Journal of Food and Pharmaceutical Science Jurnal Kedokteran Brawijaya Jurnal Kesehatan Gigi Jurnal Riset Kesehatan Poltekkes Depkes Bandung Ta'dib: Jurnal Pendidikan Islam Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) Jurnal Kesehatan Gigi dan Mulut (JKGM) Cermin Dunia Kedokteran Dental Therapist Journal Jurnal PRIMED:Primary Education Journal atau Jurnal Ke-SD An Jurnal Terapi Gigi dan Mulut Journal of Food and Pharmaceutical Sciences Jurnal Terapis Gigi dan Mulut
Supriyanto, Irwan
Unknown Affiliation
Religion Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Figs Fruit Act as Adequate Anti-Inflammatory Agents against Injured Intestines and Memory Impairment of Acute Hypoxia-Induced Rats Naurasarah, Zhafira; Meliala, Andreanyta; Supriyanto, Irwan; Onky Silvana Wijaya, Yogik; Narwidina, Paramita; Emmanuela Selamat, Claire; Kaila Priandika, Rangga
Journal of Food and Pharmaceutical Sciences Vol 13, No 3 (2025): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.20650

Abstract

Acute hypoxia (AH) may induce inflammation, increase reactive oxygen species (ROS) production, and play an important role in disrupting mucosal integrity and memory impairment through the gut-brain axis. As such, this study aimed to investigate the protective effects of Ficus carica puree (FCP) in rats with AH (10% O2, 90% N2, 4h) - induced intestinal injury. Thirty male Sprague-Dawley rats were divided into 6 groups: NC (negative control, untreated), PC (positive control), VC (vehicle, treated with corn oil), and FC1, FC2, and FC3 (FC1, 2, and 4 mL of FCP/200g). Histopathological analysis of the ileum, the levels of nitric oxide (NO), and tumor necrosis factor-α (TNF-α) were measured in plasma, and the novel object recognition (NORT) was used as a behavior test. The ileal tissues of FC1, FC2, and FC3 groups showed fewer inflammatory cells and less tissue damage than the NC group. The FCP exhibited non-dose-dependent anti-inflammation activity in TNF-α, NO, IL-6 levels, and histopathological analysis. Rats receiving all doses of FCP spent more time exploring the new object in NORT, suggesting the benefits of the phenolic compounds in Ficus carica as a functional food in alleviating the inflammatory and oxidative impacts of AH-induced intestinal injury.
Effectiveness of Social Skills Training to Improve Social Functioning Scores in Schizophrenia Patients at X Lawang Mental Hospital Ratna, Dwi; Supriyanto, Irwan; Pratiti, Budi
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.10

Abstract

Disability can cause social dysfunctions that affect daily activities, social interaction, and work, which has a significant impact on the quality of life of schizophrenics so that they depend on other people. The use of pharmacotherapy alone is not enough; psychosocial interventions such as social skills training (SST) is needed to improve social functioning in schizophrenic patients. Incorporating social skills training (SST) into a multifaceted treatment and rehabilitation program is deemed significant. The study aimed to determine the effect of social skills training to improve social functions in schizophrenia patients in X Lawang Mental Health. This study used a pre-experimental design with one group pre-test and post-test. Of 40 patients with schizophrenia who were admitted to X Lawang Mental Health fulfilled the inclusion and exclusion requirements. Social function scores were measured using the Personal and Social Performance (PSP) instrument before and after the social skills training intervention. The level of significance of statistical tests is stated at p<0.05. Data analysis used the Wilcoxon test and linear regression. There was significant difference in social functioning scores between before and after social skills training with a value of p=0.000 (p<0.05). The results of the multivariate linear regression test showed that social skills training had a statistically significant effect to improve social function scores with a value of p=0.000. Social skills training has a significant effect to improve social functioning scores in schizophrenics at X Lawang Mental Health.
Co-Authors Aprilina, Reza Asri Basiran Chaerudin, Denden Ridwan Chairunnisa, N Syifa Damayanti, Rida Devy Octaviana Edi Suresman Emmanuela Selamat, Claire Erni, Nani Fajziah, Mau'lina Febrianty, Fitria Ganeswara, Ganjar Muhammad Heriyanto, Yonan hilma paramita Ibrahim, Rizal Isnaya, Purwa Riana Kaila Priandika, Rangga Laela, Dewi Sodja Laut, Deru Marah Lestari, Diyah Woro Dwi Meliala, Andreanyta Muh Amin, dwi aisyah Narwidina, Paramita Naurasarah, Zhafira Neneng Nurjanah Nurazizah, Febriliany Nurnaningsih, Hera Nurul Fatikhah, Nurul Onky Silvana Wijaya, Yogik Praptiwi, Yenni Hendriani Praptiwi, Yenny Hendriani Pratiti, Budi Purnama, Meta Mukhsinin ratna, dwi Restuning, Sekar Rustandi, Gista Septiani Septianawati, Paramita Siti Fatimah Sri Mulyanti Tiurmina Sirait Tri Widyastuti Ulfah Utami YM, Yosi Fauziyah Zahra, Nadzira Audi