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Karmilah
Politeknik Bina Husada Kendari
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PENINGKATAN PENGETAHUAN SISWA SMA NEGERI 1 KENDARI TENTANG SWAMEDIKASI DENGAN METODE CBIA (CARA BELAJAR INSAN AKTIF) Musdalipah, Musdalipah; Daud, Nur Saadah; Fauziah, Yulianti; Karmilah, Karmilah; Yusuf, Muh. Ilyas; Rusli, Nirwati; Setiawan, Muh. Azdar; Wulaisfan, Randa; Ado, Moldefya Wahid; Audina, Fina
JMM - Jurnal Masyarakat Merdeka Vol 1, No 1 (2018): NOVEMBER
Publisher : Universitas Merdeka Pasuruan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (603.773 KB) | DOI: 10.51213/jmm.v1i1.3

Abstract

Swamedikasi adalah pengobatan dilakukan oleh masyarakat tanpa menggunakan resep dokter. Survey Sosial Ekonomi Nasional (SUSENAS) menunjukkan lebih dari 66% masyarakat melakukan pengobatan sendiri (swamedikasi). Siswa (i) SMA merupakan kelompok masyarakat yang masih labil dan mempunyai pengetahuan yang terbatas dalam menggunakan obat. Metode Cara Belajar Insan Aktif (CBIA) adalah model edukasi pemberdayaan siswa agar lebih terampil memilih obat sehingga swamedikasi menjadi lebih efektif, aman, dan hemat biaya. Tujuan kegiatan ialah untuk mengetahui peningkatan pengetahuan siswa (i) SMA Neg.1 Kendari tentang swamedikasi dengan metode CBIA. Kegiatan dilakukan di SMA Negeri 1 Kendari pada bulan April 2017 dengan desain pra-experimental one-group pretest-posttest. Kegiatan menggunakan kuesioner dengan analisis data menggunakan uji T-test. Berdasarkan hasil analisis uji sample paired T-test 0,026<0,05) menunjukkan pengaruh yang bermakna pemberian metode CBIA terhadap peningkatan pengetahuan siswa (i) SMA Negeri 1 Kendari tentang swamedikasi.Kata Kunci : Swamedikasi, Pengetahuan, CBIA
Aktivitas Antibakteri Rimpang Meistera chinensis terhadap Bakteri Staphylococcus aureus ATCC 25023 dan Eschericia coli ATCC 35218 Secara Difusi Agar Karmilah; Reymon; Daud, Nur Saadah; Badia, Esti; Yodha, Agung Wibawa Mahatva; Setiawan, Muh. Azdar; Tee, Selfyana Austin; Musdalipah
Biota : Jurnal Ilmiah Ilmu-Ilmu Hayati Vol 8, No 1 (2023): February 2023
Publisher : Universitas Atma Jaya Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24002/biota.v8i1.5651

Abstract

Meistera chinensis merupakan generasi baru famili Zingiberaceae yang tumbuh di Sulawesi Tenggara. Ekstrak buah mengandung metabolit sekunder seperti flavonoid, terpenoid, alkaloid, steroid, dan tanin yang memiliki efektivitas sebagai antioksidan dan antibakteri. Namun, belum ada laporan tentang antibakteri pada bagian rimpang. Penelitian ini bertujuan untuk mengetahui kandungan metabolit sekunder dan aktivitas antibakteri ekstrak etanol rimpang M. chinensis. Serbuk kering rimpang M. chinensis diekstraksi dengan maserasi menggunakan pelarut etanol 96%. Ekstrak dipekatkan menggunakan rotary vacuum evaporator. Metode analisis aktivitas antibakteri menggunakan difusi agar dengan konsentrasi ekstrak 10%, 20%, 30%, dan kontrol positif (Ciprofloxacin 30µg) terhadap Staphylococcus aureus ACTT 25023 dan Escherichia coli ACTT 35218 selama 24 jam. Hasil penelitian menunjukkan bahwa ekstrak etanol rimpang M. chinensis mengandung flavonoid, saponin, alkaloid, steroid, dan fenol, Ekstrak terbukti menghambat pertumbuhan E. coli dengan diameter zona hambat rata-rata secara berturut-turut pada konsentrasi 10%, 20%, dan 30% sebesar 6,08±1,79; 8,16±0,11 dan  10,57±1,34 mm. Pada S. aureus, zona hambat masing-masing konsentrasi 10%, 20%, dan  30% sebesar 5,02±0,79; 6,01±0,69; 8,03±0,76. Analisis One Way ANOVA menunjukkan perbedaan aktivitas antibakteri yang signifikan antar konsentrasi ekstrak pada E. coli dan S. aureus. Dapat disimpulkan rimpang M. chinensis memiliki aktivitas sebagai antibakteri. 
Pembuatan Teh Kombucha dengan Tambahan Tanaman Herbal sebagai Minuman Probiotik Kesehatan di Desa Soropia Idris, Sri Aprilianti; Pryangan, Wulandari; Karmilah, Karmilah; Firdayanti, Firdayanti; Fusvita, Angriani; Yodha, Agung Wibawa Mahatva; Wenty, Darmayanita; Susanti, Susanti; Zeptiano, Zeptiano; Dhea, Alisha
Jurnal Pengabdian Masyarakat: Pemberdayaan, Inovasi dan Perubahan Vol 5, No 6 (2025): JPM: Pemberdayaan, Inovasi dan Perubahan
Publisher : Penerbit Widina, Widina Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59818/jpm.v5i6.2226

Abstract

Kombucha tea is the result of the fermentation of tea and sugar solution using Symbiotic Culture of Bacteria and Yeast (SCOBY) which produces a drink with a fresh taste, distinctive aroma, and contains various bioactive compounds, such as organic acids, vitamins, and probiotics. The addition of herbal ingredients to kombucha tea, such as ginger, lemongrass, or mint leaves, can enhance the taste and improve health. Soropia Village as a coastal area has great potential in the development of products based on natural ingredients. However, limited knowledge and skills of the community in processing ingredients into value-added products remain a barrier. The purpose of community service is to increase knowledge and training to the community in Soropia Village on making kombucha tea with the addition of herbs as a health drink rich in probiotics. The methods used are socialization, education, training and evaluation. This activity was carried out in Soropia Village with the target group of the Soropia Village Family Welfare Movement (PKK). This training enables the community to know and understand how to make kombucha tea with the addition of herbal plants as a health drink that can be made into a product. The training and interviews following teh kombucha tea-making workshop demonstrated that all participants understood the material, with nearly 30 participants answering the questionnaire correctly. After the training, participants were able to independently make kombucha tea with ginger at home.ABSTRAKTeh kombucha merupakan hasil fermentasi larutan teh dan gula menggunakan Symbiotic Culture of Bacteria and Yeast (SCOBY) yang menghasilkan minuman dengan cita rasa segar, beraroma khas, serta mengandung berbagai senyawa bioaktif, seperti asam organik, vitamin, dan probiotik. Penambahan bahan herbal pada teh kombucha, seperti jahe, serai, atau daun mint, dapat meningkatkan cita rasa sekaligus dapat meningkatkan kesehatan. Desa Soropia sebagai salah satu wilayah pesisir memiliki potensi besar dalam pengembangan produk berbasis bahan alami. Namun, keterbatasan pengetahuan dan keterampilan masyarakat dalam mengolah bahan menjadi produk bernilai tambah masih menjadi kendala. Tujuan pengabdian untuk meningkatkan pengetahuan dan pelatihan kepada masyarakat di desa soropia tentang pembuatan teh kombucha dengan tambahan herbal  sebagai minuman kesehatan yang kaya probiotik. Metode yang digunakan adalah sosialisasi, edukasi, pelatihan dan evaluasi. Kegiatan ini dilaksanakan di desa soropia dengan target kelompok PKK desa Soropia. Pelatihan ini membuat masyarakat dapat mengetahui dan memahami bagaimana cara pembuatan teh kombucha dengan tambahan tanaman herbal sebagai minuman kesehatan yang dapat dijadikan produk. Hasil pelatihan dan wawancara setelah dilakukan pengabdian pembuatan teh kombucha, seluruh peserta memahami materi yang diberikan dengan hasil jawaban hampir 30 peserta menjawab kuesioner dengan benar. Setelah pelatihan, peserta dapat membuat teh kombucha dengan tambahan jahe secara mandiri dirumah.
Chemotaxonomy in the Etlingera Genus from Sulawesi, Indonesia: Design and molecular docking of antioxidant marker RINI HAMSIDI; KARMILAH KARMILAH; NUR SAADAH DAUD; MUHAMMAD HAJRUL MALAKA; AGUNG WIBAWA MAHATVA YODHA; MUSDALIPAH MUSDALIPAH; ARFAN ARFAN; SAHIDIN SAHIDIN
Biodiversitas Journal of Biological Diversity Vol. 25 No. 2 (2024)
Publisher : Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/biodiv/d250202

Abstract

Abstract. Hamsidi R, Karmilah, Daud NS, Malaka MH, Yodha AWM, Musdalipah, Arfan, Sahidin. 2024. Chemotaxonomy in the Etlingera Genus from Sulawesi, Indonesia: Design and molecular docking of antioxidant marker. Biodiversitas 25: 449-457. Etlingera is one of the important genera in the Zingiberaceae family because of its potential uses. Several studies have been conducted on the Genus Etlingera as nutraceuticals and drugs. Recently new species have been found in the Sulawesi Region, Indonesia, namely E. canaria A.D.Poulsen and E. echinulate A.D.Poulsen. Based on literature review through sciencedirect and springer link, both species unknown for their chemical and pharmacological content, so it is necessary to continue to reveal the deeper potential. The fruits of E. calophrys (K.Schum.) A.D.Poulsen, E. canaria and E. echinulate were extracted with methanol by maceration method. The chemical content of each extract was analyzed using a Liquid Chromatography Mass Spectrometer (LCMS). Antioxidant activity was tested based on the 1,1-Diphenyl-2-Picrylhydrazyl (DPPH) method. The ability as an antioxidant is proven by the molecular interactions of marker compounds in inhibiting xanthine oxidase. The secondary metabolites contained in the fruit extracts of E. calophrys, E. canaria and E. echinulate are E-p-Coumatic acid, 1,5-Dimethyl citrate, Trimethyl citrate, Crocetin, Tanshinone IIA, Ethinyl Estradiol, Yakuchinone B, Anisalacetone, Yakuchinone A, Nobilin, ?-Estradiol, Momor-cerebroside I, Spinasterone, 12-Hydroxy-methyl abietate, Spinasterol, 2,3-Dihydroxypropyl oleate, 11-Octadecenoate acid methyl ester, Stigmastan-3,6-dione, b-Sitosterol- 3-O-b-D-glucopyranoside, Trilaurin, 28-O-Hexahydrophthalate and Fasciculol C. Yakuchinone A and Yakuchinone B are chemotaxonomic marker compounds identified in all species. The antioxidant properties of each extract of 42.27±0.53, 46.59±0.81 and 35.66±0.73 mg/L have been proven by the molecular interactions of the marker compounds in their ability to act as xanthine oxidase inhibitors. The compounds Yakuchinone A and Yakuchinone B are thought to be responsible for the pharmacological activity of the species E. calophrys, E. canaria and E. echinulate. Yakuchinone A and Yakuchinone B are marker compounds because they are distributed in all samples.
Nonsense Mutation (c.1425G>A-p.Trp475Ter) Associated with Oculocutaneous Albinism Type 1A (OCA1A) in Yogyakarta Karmilah, Karmilah; Dian Pratiwi, Arini; Nur Handayani, Niken Satuti
Jurnal Kedokteran Brawijaya Vol. 33 No. 4 (2025)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2025.033.04.8

Abstract

Oculocutaneous Albinism (OCA) is a disorder characterized by impaired melanin synthesis that leads to hypopigmentation of the skin, hair, and eyes, accompanied by distinct ocular abnormalities. The global prevalence of all forms of albinism is approximately 1 in 17,000 individuals, and OCA1 is the most common type. OCA1 results from mutations in the TYR gene and specifically involves a complete loss of tyrosinase enzyme function, resulting in a total absence of pigment in the skin, eyes, and hair. This case report describes two male patients with congenital symptoms of extremely light or depigmented skin and hair. Both presented with white eyelashes and eyebrows, grayish irises, and ocular abnormalities, including nystagmus, photophobia, and strabismus. The analysis showed a genetic variant in the exon of the TYR gene with the mutation variant c.1425G>A/p.Trp475Ter and was found to be a nonsense mutation.
THE INFLUENCE OF THE AUDIT COMMITTEE AND FRAUD DIAMOND ON FRAUDULENT FINANCIAL STATEMENT IN MANUFACTURING COMPANIES OF VARIOUS INDUSTRIES SECTOR LISTED ON THE INDONESIA STOCK EXCHANGE Suripto - Suripto; Karmilah Karmilah
International Journal of Economics, Business and Accounting Research (IJEBAR) Vol 5 No 3 (2021): IJEBAR : Vol. 05, Issue 03, September 2021
Publisher : LPPM ITB AAS INDONESIA (d.h STIE AAS Surakarta)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29040/ijebar.v5i3.2721

Abstract

Fraudulend financial statement are generally difficult to detect, due to the various motivations behind the actions taken. The purpose of this study is to prove the effect of the audit committee and the fraud diamond on the fraudulent financial statement by looking at the effect of the variables that are proxies in this study. The population in this study were manufacturing companies in the various industrial sectors in 2015-2019. The sampling technique in this research is purposive sampling. The type of data used is secondary data from the Indonesia Stock Exchange in the form of an annual report. The sample in this study were 22 companies, with 110 observational data. The type of research method used is panel data regression analysis method. The results of the analysis of this study indicate that simultaneously the audit committee and the fraud command element have an effect on the fraudulent financial statement and partially show that only financial stability and financial targets have an effect on the fraudulent financial statement. While the financial target variables, nature of industry, ineffective monitoring, change in auditors, change of directors and audit committees have no effect on fraudulent financial statement. Keywords: Audit Committee, Fraud Diamond, Fraudulent Financial Statements, Manufacturing Companies of Various Industries Sector
Co-Authors Achnis Jum Akbar Ado, Moldefya Wahid Agung Wibawa Mahatva Yodha Agustini Angraeni, Ni Kadek Ayu Angriani Fusvita Anisa Arfan ARFAN ARFAN Audina, Fina Badia, Esti Daud, Nur Saadah Dhea, Alisha Dian Pratiwi, Arini Eny Nur Hikma Eny Nurhikma Evi Apriani Arifin Evi Nur Indah Sari Fadhliyah Malik Fakhrurazi, Muh. Fauziah, Yulianti Firdayanti, Firdayanti Fristiohady, Adryan Hasnawati Hasnawati Indriyani Pratiwi Hapsari Inggit Suryaningsih Irma Malaka, Muhammad Hajrul Muh. Fakhrurazi MUHAMMAD HAJRUL MALAKA Muhammad Ilyas Muhammad Ilyas Y Muhammad Syaiful Saehu Musdalipah Niken Satuti Nur Handayani Nirwati Rusli Nuralifah Nuralifah, Nuralifah Nurhikma Nurhikma Reymon, Reymon Rifcha Selviana Puput RINI HAMSIDI Rini Hamsidi Rusli, Nirwati Sahidin Sahidin Santi Oktaviani, Santi Selfyana Austin Tee Setiawan, Muhammad Azdar Sri Aprilianti Idris Sri Susanti Suripto Suripto Susanti Susanti Wenty, Darmayanita Wulaisfan, Randa Wulandari Pryangan Yusuf, Muh. Ilyas Zeptiano, Zeptiano