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All Journal Medula Jurnal Belantara ULIN: Jurnal Hutan Tropis Andalas obstetrics and gynecology journal JK Unila (Jurnal Kedokteran Universitas Lampung) Archives Pharmacia Jurnal Pengabdian Fakultas Pertanian Universitas Lampung JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai
Rodiani, Rodiani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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Journal : Medula

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Penggunaan Tanaman Mangrove Sebagai Obat Herbal di Lampung Selatan Rodiani, Rodiani; Islamy, Nurul
Medula Vol 14 No 5 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i5.1085

Abstract

As a means of adaptation to extreme habitats, mangrove plants produce a variety of secondary metabolic substances that have the potential as herbal medicines. Empirically, coastal communities have utilized and proven the medicinal properties of mangrove plants. The study’s objective was to determine the use of mangrove plants as herbal medicine in Pematang Pasir, South Lampung. The use of mangroves as medicine was obtained through in-depth interviews followed by descriptive analysis and calculation of species use value, plant part value, and fidelity level. The results showed that the use of mangrove plants as herbal medicine in the Pematang Pasir area, Ketapang District, South Lampung, ethnically dominated by the Serang ethnic group (54%), with the majority having completed junior high school education (38.1%), economically classified as middle-income based on BPS criteria (2020), with the majority working as fishermen and farmers, and the majority being adults (over 40 years old). Based on the Species Use Value (SUV), R. apiculata is the most popular and widely used species by the community. Based on Plant Part Value (PPV) analysis, leaves are the most commonly used part as herbal medicine, with over 75% of the population using mangrove leaves as a source of treatment, while other parts are less utilized. The level of community trust in the benefits of mangrove plants as medicine is relatively low, with figures below 50%. Rhizophora apiculata is the only species accepted with a high level of confidence of 88%, particularly as a wound or antiseptic medicine.
Pengaruh Pemberian Ekstrak Biji Kopi Robusta (Coffea canephora) Lampung Terhadap Gambaran Histopatologi Tubulus Proksimal Ginjal Tikus Putih (Rattus norvegicus) Jantan Galur Sprague-dawley yang Diinduksi Monosodium Glutamat Salsabila, Aina; Wulan, Anggraeni Janar; Rodiani, Rodiani
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1335

Abstract

Excessive consumption of monosodium glutamate can form free radicals and is nephrotoxic which causes damage to organs, one of which is the kidneys, especially in the proximal tubule. Chlorogenic acid compounds contained in coffee beans have potential as antioxidants and nephroprotective agents. Coffee consumption at a certain dose is assumed to prevent and or reduce damage to the proximal kidney tubules of rats caused by free radicals. This research is an experimental study with a completely randomized design (CRD) with a Posttest Only Control Group Design approach. This research was conducted for 14 days. The samples used were 25 rats which were divided into 5 groups, namely K- (aquades 3 ml/day), K+ (MSG 4 g/kgBW/day), P1, P2, and P3 (MSG 4 g/kgBW/day). and Lampung robusta coffee bean extract 1 ml/200gBW/day with a concentration of 0.006 g/ml; 0.012 g/ml; 0.024 g/ml respectively) with each group consisting of 5 rats. Kidney histopathological assessment was carried out by observing kidney preparations in 5 visual fields each in 400x magnification. The mean total score of proximal tubular damage in groups K-, K+, P1, P2, and P3 respectively was 2.48; 3.40; 2.80; 2.64; 3.04. One Way ANOVA test obtained p value = 0.001 (p <0.05). Post Hoc LSD test on proximal tubular damage scores showed a significant difference (p<0.05) between K- and K+ (p=0.000), K- and P3 (p=0.008), K+ and P1 (p=0.005) , K+ with P2 (p=0.001), and P2 with P3 (p=0.047). There is an effect of administration of Lampung Robusta (Coffea canephora) coffee bean extract on the histopathological appearance of the kidney proximal tubules of male rats (Rattus norvegicus) strain Sprague-Dawley induced by monosodium glutamate.
UJI DAYA HAMBAT EKSTRAK DAUN LIDAH MERTUA (Sansevieria trifasciata laurentii) TERHADAP PERTUMBUHAN BAKTERI Staphylococcus aureus Saputra, Kurnia Hadi; Apriliana, Ety; Rodiani, Rodiani; Oktarlina, Rasmi Zakiah
Medula Vol 15 No 2 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i2.1579

Abstract

Infectious and communicable diseases remain one of the leading causes of mortality in Indonesia and worldwide. Several pathogenic bacteria can cause infections, one of which is Staphylococcus aureus. This bacterium can lead to a variety of conditions, including mastitis, dermatitis (skin inflammation), respiratory tract infections, impetigo, abscesses, toxic shock syndrome, and food poisoning. With the advent of antibiotics, an increasing number of bacterial strains have developed antibiotic resistance. The primary cause of this resistance is the widespread and irrational use of antibiotics, which allows some bacteria to survive and become resistant. The snake plant (Sansevieria trifasciata laurentii) contains compounds with antibacterial properties, such as tannins, saponins, and flavonoids. This study aimed to investigate the antibacterial activity of snake plant extract against Staphylococcus aureus. The research design used was a laboratory-based observational study. The antibacterial activity of the snake plant leaf extract was tested at concentrations of 20%, 40%, 60%, 80%, and 100% against Staphylococcus aureus using the dilution method to determine the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). The results showed that the snake plant extract exhibited antibacterial activity against Staphylococcus aureus at all tested concentrations (20% to 100%). The MIC was observed at a concentration of 20%, while the MBC was found at 40%. These findings confirm that the extract of Sansevieria trifasciata laurentii has inhibitory effects on the growth of Staphylococcus aureus.
Co-Authors Ambarwati, Yuli Aminuyati Anggraeni Janar Wulan, Anggraeni Janar Bainah Sari Dewi Berta Putri Duryat, Duryat Dwi Indria Anggraini Efriyan Imantika Ety Apriliana Fauzi Ahmad Muda Hamidi, Syahrul Hardiyanti, Rahma Indri Windarti Irawan, Sandy Erggi Janar Wulan, Anggraini Kambey, Kevin Kornelius Luvika, Stefhani Gista Manaf, Latifah Abd. Melya Riniarti Muhammad Yusran Mukhlis Imanto, Mukhlis Nurul Islamy Prabowo, Arif Yudho Rara Diantari Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Rizki Hanriko Rommy Qurniati Rudiyanto, Waluyo Salsabila, Aina Samsul Bakri Saputra, Kurnia Hadi Saragih, Yoppie Jordan Setiawan, Sony Slamet Budi Yuwono Susianti, Susianti Syahrul Hamidi Nasution SYAIFUL BAHRI Tri Maryono Tyas Priyatini