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Test of the inhibitory power of red betel leaf extract (Piper crocatum) against stapylococcus aureus bacteria: Uji Daya Hambat Ekstrak Daun Sirih Merah (Piper crocatum) Terhadap Pertumbuhan Bakteri Stapylococcus aureus rahayu putri, Andini; Asdinar, Asdinar; Fatimah, Fatimah
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 1 No. 2 (2023): Bulan November 2023 Faskes : Jurnal Farmasi, Kesehatan dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v1i3.2392

Abstract

Latar Belakang : Bakteri Staphylococcus aureus merupakan salah satu bakteri yang dapat menyebabkan penyakit infeksi, seperti infeksi supuratif dengan angka keparahan yang bervariasi. Daun sirih merah (Piper crocatum) merupakan salah satu tanaman herbal yang banyak dijumpai di Indonesia yang bermanfaat sebagai obat, mengandung flavonoid, alkaloid, saponin dan minyak atsiri yang bersifat antibakteri. Tujuan : Tujuan penelitian ini adalah untuk mengetahui uji daya hambat ekstrak daun sirih merah terhadap pertumbuhan bakteri Staphylococcus aureus. Metode : Penelitian ini merupakan penelitian Experimental Laboratories menggunakan disc deffision untuk melihat efek daun Sirih merah. Dimana ekstrak daun sirih merah diperoleh dengan metode maserasi yang kemudian di variasikan kedalam beberapa perlakuan konsentrasi yaitu 20%, 40%, 60%, 80%, dan 100% serta kontrol positif tetracylin dan kontrol negatif aquades. Hasil Penelitian : Hasil penelitian menunjukkan bahwa ekstrak daun sirih merah mampu menghambat pertumbuhan bakteri Staphylococcus aureus dengan aktivitas kuat. Dari hasil analisis statistik menunjukkan masing-masing data terdistribusi dengan normal yang memenuhi syarat untuk melakukan uji One-Way Anova dari hasil akhir menunjukkan nilai p<0,005 sehingga paling tidak terdapat rerata bermakna antara kelompok data.Kesimpulan : Adapun kesimpulan dari penelitian ini adalah ekstrak daun sirih merah dengan konsentrasi 40%, 60%, 80% dan 100% efektif dalam menghambat pertumbuhan bakteri Staphylococcus aureus.
Testing The Antibacterial Effectiveness Of Pegagan (Centela Asiatica) Leaf Extract Using The Well Method On The Growth Of The Bacteria Staphylococcus Aureus: Uji Efektivitas Antibakter Ekstrak Daun Pegagan (Centela Asiatica) Dengan Metode Sumuran Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Yulianto, Delmi; Asdinar, Asdinar; Dr.Aszrul AB, Dr.Aszrul AB
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 1 No. 2 (2023): Bulan November 2023 Faskes : Jurnal Farmasi, Kesehatan dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v1i3.2396

Abstract

Bakteri Staphylococcus aureus adalah salah satu bakteri yang dapat menyebabkan penyakit infeksi, seperti infeksi suparatif dengan angka keparahan yang bervariasi. Bakteri ini salah satu bakteri yang resisten sehingga menjadi masalah tersendiri. Pegagan (Centela Asiatica) merupakan salah satu tumbuhan yang digunakan sebagai obat. Salah satu manfaat yang bisa didapatkan dari daun pegagan (Centela Asiatika) adalah antibakterinya. Metode:  Metode penelitian experimental laboratory, menggunakan desain post test only control group. Ekstrak pegangan diperoleh dengan menggunakan metode maserasi yang kemudian divariasikan kedalam beberapa konsentrasi 20%, 40%, 60%, 80%, dan 100% serta kontrol positif ciprofloxacin dan kontrol negatif aquades. Dilanjutkan dengan metode difusi sumuran untuk menguji daya hambat, lalu hasil yang didapatkan diolah menggunakan uji SPSS menggunakan one way anova. Hasil: Hasil penelitian uji daya hambat ekstrak daun pegagan (Centela Asiatica) terhadap pertumbuhan bakteri Staphylococcus aureus dengan konsentrasi 20%, 40%, 60%, 80%, dan 100% memiliki respon hambat yaitu 0  mm, 12,6  mm, 13,5  mm, 16.1 mm, 18 mm dan hasil uji statistik menunjukkan bahwa nilai P=0,00 yang berarti nilai P< 0,05. Simpulan dan saran: Adapun kesimpulannya yaitu menunjukkan bahwa ekstrak daun pegagan dapat menghambat pertumbuhan bakteri Staphylococcus aureus
Analisis Kadar Asam Lemak Bebas Pada Minyak Goreng Kelapa Murni Sebelum dan Sesudah Penggorengan di Desa Pakubalaho Rahmi, Alidah; Asdinar, Asdinar; Artati, Artati
FASKES : Jurnal Farmasi, Kesehatan, dan Sains Vol. 1 No. 2 (2023): Bulan November 2023 Faskes : Jurnal Farmasi, Kesehatan dan Sains
Publisher : Program Studi Farmasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32665/faskes.v1i3.2403

Abstract

Latar belakang: Minyak goreng kelapa murni adalah minyak goreng yang dibuat secara tradisional yang secara fisik berwujud  cairan yang berwarna bening sampai kuning kecoklatan dan memiliki karakteristik bau yang khas. Warna minyak kelapa murni dipengaruhi oleh bahan dasar dan suhu selama proses pengolahan. Tujuan: tujuan penelitian untuk mengatahui kadar asam lemak bebas pada minyak goreng kelapa murni sebelum dan sesudah 3 kali dipakai. Metode: metode penelitian yang digunakan pada penelitian ini adalah free eksperimental. Hasil: Hasil penelitian dari penelitian ini Menunjukkan terjadinya peningkatan jumlah kadar asam lemak bebas pada minyak goreng kelapa murni yaitu pada sampel 1 sebelum dipakai 0,24%, sesudah 1 kali dipakai 0,66%, sesudah 2 kali diapakai 0,74%, sesudah 3 kali dipakai 1,44%. Pada sampel 2 sebelum dipakai 0,14 %, sesudah 1 kali dipakai 0,18 %, sesudah 2 kali dipakai 0,24 %, dan sesudah 3 kali dipakai 0,30. Pada sampel 3 sebelum dipakai 0,12%, sesudah 1 kali dipakai 0,60%, sesudah 2 kali dipakai 0,76%, sesudah 3 kali pakai 1,4%. Simpulan dan Saran: bahwa kadar asam lemak bebas pada minyak goreng kelapa murni sebelum dan sesudah 3 kali penggorengan masih memenuhi batas yang telah ditetapkan oleh Standar Nasional Indonesia (SNI) 01-3741-2013 yaitu 0,30 % dan minyak yang digunakan sebanyak 3 kali penggorengan masih layak untuk dikonsumsi
Identification of Dermatophytes Causing Tinea Unguium in Fisherman in Tanah Lemo Subdistrict Asdinar, Asdinar; Ananda, Alya; AB, Aszrul
Journal of Multidiscipline and Collaboration Research Vol. 1 No. 2 (2024)
Publisher : Yayasan Pendidikan dan Pengembangan Harapan Ananda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58740/jmcr.v1i2.283

Abstract

Nail infection or tinea unguium is a disease caused by dermatophyte fungi and often occurs in fisherman due to their activities in wet environments without protection such as gloves or boots. Common symptoms found include nail damage, thickening, nail lifting, uneven broken nails, loss of shine, and discoloration to yellow, brown, or black. This study aims to identify the types of dermatophyte fungi that cause tinea unguium in fisherman in Tanah Lemo Village. This study used a qualitative approach with a fungal culture method using Saboraud Dextrose Agar (SDA) media and microscopic examination using 10% KOH solution. The study population was 115 fisherman, with samples of 25 people taken from their nails through macroscopic and microscopic examination methods. The results showed that a wet and dirty work environment is a major risk factor for fungal infections in fisherman's nails. The implication of this study is the importance of prevention efforts through education on the use of personal protective equipment, such as gloves and boots, to reduce the risk of fungal infections. Additional factors such as the length of exposure to wet environments also affect fungal growth, so better risk management of the work environment is needed.
Results of Internal Quality Assurance for Ureum Parameters at H. Andi Sulthan Daeng Radja Hospital Asdinar, Asdinar; Hasanuddin, A R Pratiwi; Jusriani, Jusriani
Journal of Multidiscipline and Collaboration Research Vol. 1 No. 2 (2024)
Publisher : Yayasan Pendidikan dan Pengembangan Harapan Ananda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58740/jmcr.v1i2.284

Abstract

Internal Quality Assurance (PMI) is a preventive and supervisory activity in the laboratory to ensure precise and accurate examination results. This study aims to evaluate the precision, accuracy, and types of analytical errors in PMI urea parameters in the laboratory of H. Andi Sulthan Daeng Radja Hospital, Bulukumba Regency. This descriptive study uses a mixed method with secondary data from PMI results for October–December 2023. The results showed that the average (Mean) urea value in October was 35.53 mg/dL, SD 1.77 mg/dL, CV 4.99%, and d 0.77%; November 35.48 mg/dL, SD 1.74 mg/dL, CV 4.89%, and d 0.88%; December 35.43 mg/dL, SD 1.81 mg/dL, CV 5.10%, and d 1.03%. The CV (precision) and d (accuracy) values are within the maximum control limits (CV ?8%, Bias ±10%). Westgard rule analysis showed violations of the 1-2s rule in October, in the form of warnings without affecting the validity of the control, while no violations were found in November–December. Conclusion: The precision and accuracy of urea parameters are in the good category based on the Levey-Jennings graph analysis and the Westgard rule.
Pemeriksaan Gula Darah pada Masayarakat Dusun Buhung Bundang Kecamatan Bontotiro Kabupaten Bulukumba Islawati, Islawati; Asdinar, Asdinar; Ridwan, Asriyani; Trisnawati Arwien, Rizky
Jurnal Pengabdian Masyarakat Vol. 2 No. 2 (2025): Jurnal Pengabdian Masyarakat
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/2025.v2i2/420/5/juramas

Abstract

Diabetes mellitus is a non-communicable disease with increasing prevalence in Indonesia, particularly in rural areas with limited access to healthcare services. The low level of public awareness regarding early detection and healthy lifestyle practices further exacerbates this condition. This community service activity aimed to conduct blood glucose screening and provide health education for elderly residents in Buhung Bundang Hamlet, Bontotiro District, Bulukumba Regency. The method employed in this program was a participatory-educational approach based on the Participatory Action Research (PAR) model. The activity was carried out in three stages: preparation, implementation, and evaluation. Supporting tools included a digital glucometer, a simple screening form, and an educational leaflet titled “Beware of Diabetes! Recognize the Symptoms, Prevent Early.” A total of 20 participants, all elderly residents, were involved in the activity. Results showed that 95% of participants had normal blood glucose levels (<140 mg/dL), while 5% (1 participant) was found to have elevated levels (≥200 mg/dL), indicating potential undiagnosed diabetes mellitus. The educational session and the leaflet effectively improved participants' awareness of diabetes risk factors and preventive measures. This program demonstrated that a participatory and educational approach in community service can be an effective preventive intervention to raise health awareness and promote early detection of non-communicable diseases in rural communities. Similar activities are recommended to be conducted regularly, involving local health volunteers as community-based health educators.
Detection of STH Worm Eggs on Students' Nails at UPT SPF SDN 258 Sakui-Kui Elementary School Islawati, Islawati; Asdinar, Asdinar; Ridwan, Asriyani
Jurnal Pengabdian Masyarakat Vol. 2 No. 1 (2024): Jurnal Pengabdian Masyarakat
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/2024.v2i1/376/5/juramas

Abstract

Helminth infections remain one of the most common parasitic diseases affecting children, particularly at the primary school level, where awareness of personal hygiene is generally low. One of the main transmission routes of this infection is through unclean hands. This community service activity at UPT SPF SDN 258 Sakui-Kui aimed to enhance students' understanding of the importance of personal hygiene, specifically by educating them on proper handwashing techniques based on WHO standards. The tools used in this activity included a whiteboard, nail clippers, a camera, a microscope, test tubes, glass slides, cover slips, stirring rods, basins, beakers, petri dishes, test tube racks, and stationery, while the materials used included nail samples from students, water, and salt. The evaluation results indicated that this activity effectively increased students' understanding of personal sanitation by up to 90%, as evidenced by observational evaluations of direct practice. Additionally, students gained knowledge that helminth eggs adhering to nails could cause infections if ingested with food. This educational initiative had a significant impact on shaping students’ personal hygiene behavior, potentially reducing the risk of parasitic infections within the school environment.
Description of Hemoglobin and Erythrocyte Levels in Tuberculosis Patients at Prof. Dr. HM Anwar Makkatutu Regional Hospital, Bantaeng Regency Asdinar, Asdinar; Dewi B , Ade Risma Zagina; Islawati, Islawati
Frontiers in Sustainable Science and Technology Vol. 2 No. 1 (2025): June
Publisher : CV. Science Tech Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69930/fsst.v2i1.230

Abstract

Data from the World Health Organization (WHO) in 2023, tuberculosis (TB) is a long-standing disease. The relationship between hemoglobin levels in tuberculosis, decreased hemoglobin levels in tuberculosis sufferers can be caused by the tuberculosis infection process. Bad habits such as staying up late, smoking, consuming alcohol, and unmet nutritional needs. While the relationship between erythrocyte levels in tuberculosis can affect all hematopoiesis series, especially in erythrocytes, when erythrocytes are infected, a reaction will occur where the life mass of erythrocytes is shortened by around 10-20 days, while in normal conditions the life mass of erythrocytes is 120 days. This research is a type of quantitative research with a descriptive research design using purposive sampling techniques. Based on the results of the study on the description of hemoglobin and erythrocyte levels in inpatients with tuberculosis at Prof. Dr. HM Anwar Makkatutu Regional Hospital, Bantaeng Regency, it was found that out of 250 samples of pulmonary tuberculosis patients, it showed that patients with predominantly normal hemoglobin and erythrocyte levels were 155 (62%) people, while patients with low hemoglobin and erythrocyte levels were 95 (38%) people.
Description of Lymphocyte Levels in Typhoid Fever Patients at H. Andi Sulthan Daeng Radja Regional Hospital, Bulukumba Regency Masba, A. Anisa; Fatimah, Fatimah; AB, Aszrul; Asdinar, Asdinar
Frontiers in Sustainable Science and Technology Vol. 1 No. 1 (2024): December
Publisher : CV. Science Tech Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69930/fsst.v1i1.235

Abstract

Typhoid fever is a systemic infectious disease characterized by fever and abdominal pain due to the spread of Salmonella bacteria. Lymphocytes are a type of agranulocyte leukocytes that have various functional roles related to immune reactions to attacks by microorganisms, foreign macromolecules, and cancer cells. The purpose of this research is the describe of lymphocyte levels in typhoid fever patients at H. Andi Sultan Daeng Radja Regional Hospital, Bulukumba Regency. This study is descriptive to see the picture of lymphocyte levels in typhoid fever patients. This study uses a total sampling technique where the samples taken were 50 patients. The results of the study showed that 22 patients (44%) had high lymphocytes (lymphocytosis), 11 patients (22%) had normal lymphocytes, and 17 patients (34%) had low lymphocytes (lymphopenia). Of the 50 patients, 22 patients (44%) had a high lymphocyte count (lymphocytosis), based on age and gender, the largest number were those aged <11 years, 27 people (54%), and 29 women (58%).
Differences in Serum Blood Sugar Levels that were Directly Checked and Delayed for 1 Hour at Room Temperature using a Gel Separator Vacuum Tube Oktaviyani , Tariska Inka; Asdinar, Asdinar; Adam, Adam; Islawati, Islawati
Frontiers in Sustainable Science and Technology Vol. 2 No. 1 (2025): June
Publisher : CV. Science Tech Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69930/fsst.v2i1.236

Abstract

Blood sugar testing is essential for diabetes management and should be fast, accurate, and affordable. This study aims to determine the difference in blood sugar levels between immediate and delayed (1-hour) serum examinations using vacuum gel separator tubes at Prof. Dr. H. M. Anwar Makkatutu Bantaeng Hospital. An observational laboratory research with a comparative quantitative design was conducted on 23 purposively selected patients undergoing routine check-ups, without a history of diabetes mellitus. Blood samples were analyzed immediately and after a 1-hour delay at room temperature. Results showed that in immediate examinations, blood sugar levels ranged from 79 to 161 mg/dL, with a mean of 109.26 mg/dL. In delayed examinations, levels ranged from 81 to 164 mg/dL, with a mean of 111.74 mg/dL. Statistical analysis revealed a significant difference between the two groups (P < 0.05). The findings suggest that delaying blood sugar testing by 1 hour can lead to measurable changes in serum glucose levels, emphasizing the importance of timely sample processing in clinical settings.