Article Per Year (5 Year)
p-Index From 2021 - 2026
3.03
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kesehatan Masyarakat Global Medical and Health Communication Public Health of Indonesia Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Kesehatan Komunitas The Indonesian Journal of Infectious Diseases Media Keperawatan Indonesia Medica Hospitalia Jurnal Ilmiah Keperawatan Imelda JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Peduli Masyarakat Indonesian Journal of Global Health research Narra J Indonesian Journal of Cancer
Murtiani, Farida
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Veterinary Other

Published : 21 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 21 Documents
Search

 1   2   3 
Comparison of c-MYC Expression between Patients with Germinal Center and Non-Germinal Center B-cell-like Diffuse Large B Cell Lymphoma Hanum, Sitti Fatimah; Hardjolukito, Endang Sri Roostini; Kusmardi, Kusmardi; Murtiani, Farida; Widiantari, Aninda Dinar; Setiawaty, Vivi
Indonesian Journal of Cancer Vol 19, No 2 (2025): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i2.1277

Abstract

Background: c-MYC expression has been used as a prognostic marker to predict prognosis and determine therapeutic strategies in both Diffuse Large B Cell Lymphoma (DLBCL) subtypes. No study on c-MYC expression associated with DLBCL has ever been conducted in Indonesia. Our study aimed to evaluate differences in c-MYC expression in both DLBCL subtypes and assess the immunophenotype profile.Method: We selected 40 DLBCL cases and divided them into Germinal Center B-cell (GCB) and non-GCB subtypes using Hans Criteria. We evaluated c-MYC expression, and a cut-off value of 60.4% was determined using Receiver Operating Characteristic (ROC) curve analysis.Results: We found that c-MYC expression was significantly higher in GCB subtypes compared to non-GCB subtypes (n = 17 (42.5%) vs n = 20 (7.5%), p 0.000 and mostly had an immunophenotype of CD10+/BCL6+/MUM1+.Conclusion: Higher c-MYC expression is found more frequently in GCB subtypes. These findings suggest that c-MYC may play a subtype-specific role in DLBCL pathogenesis, potentially influencing therapeutic decisions for Indonesian patients. Future studies should validate these results in larger, multi-center cohorts and explore the mechanistic link between c-MYC and the GCB subtype and its clinical implications for targeted therapies.
Biomarkers for predicting COVID-19 mortality: A study at Sulianti Saroso Infectious Disease Hospital, Indonesia Maemun, Siti; Widiantari, Aninda D.; Murtiani, Farida; Herlina, Herlina; Tanjungsari, Dian W.; Wijiarti, Kunti; Pratiwi, Tiara Z.; Matondang, Faisal; Rusli, Adria; Rivaldiansyah, Rivaldiansyah; Tampubolon, Maria L.; Mariana, Nina; Setiawaty, Vivi; Purnama, Tri B.
Narra J Vol. 5 No. 2 (2025): August 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i2.1936

Abstract

The high transmissibility and mortality rates of the COVID-19 pandemic pose significant challenges. Patients can deteriorate rapidly, making it crucial to identify laboratory biomarkers for high-risk individuals. The aim of this study was to evaluate the predictive value of various laboratory parameters, including C-reactive protein (CRP), D-dimer, ferritin, neutrophil-to-lymphocyte ratio (NLR), prothrombin time (PT), and procalcitonin (PCT), in predicting COVID-19 mortality. A retrospective cohort study was conducted at Sulianti Saroso Infectious Disease Hospital, where COVID-19 patients were categorized into survivors and non-survivors. The Mann-Whitney test was used to assess group differences, while receiver operating characteristic (ROC) curve analysis was performed to evaluate the predictive performance of each biomarker, with Youden's index (J) determining optimal cut-off values. Kaplan-Meier analysis was used to compare median survival times, and Cox regression assessed hazard rates and the relationship between biomarkers and mortality. A total of 1,598 patients were analyzed, the majority of whom were admitted with oxygen saturation levels >95% and classified as having mild to moderate disease severity. Among them, 216 patients died, resulting in a mortality rate of 13.52%. Significant variations in mortality rates were observed along the survival functions for NLR, ferritin, D-dimer, CRP, and PCT (p<0.001). The survival curves for these biomarkers demonstrated distinct trends across tertiles over time. Among hematological markers, NLR was significantly associated with mortality (p<0.001), with a 1.5–2.2% increased risk per unit increase. Biochemical markers (complete blood count) proved to be more effective than hematological parameters (NLR, ferritin, PT, D-dimer, CRP, PCT) when evaluating individual prognostic performance. Bivariate analysis of CRP, D-dimer, ferritin, NLR, PT, and PCT between survivors and non-survivors showed significant differences. Notably, NLR and PCT were highly relevant for predicting disease prognosis and mortality, with sensitivity and specificity values exceeding 80%.
Predicting Unfavorable Treatment Outcomes in Multi-Drug Resistance Tuberculosis Patients: A Retrospective Study in Jakarta, Indonesia Hadayna, Saila; Adisasmita, Asri C.; Murtiani, Farida
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6664

Abstract

Treatment of multidrug-resistant tuberculosis (MDR-TB) with a short-term regimen offers promise in terms of higher effectiveness and reduced therapy duration. However, treatment failure remains a major challenge in its implementation. This study aimed to identify predictive factors associated with unfavorable treatment outcome (UTO) among MDR-TB patients receiving the short-term regimen in DKI Jakarta Province from 2020 to 2022. Methods: A retrospective cohort study, using data from the National TB Information System (SITB). We retrieved all MDR-TB patients who started short-term treatment regimens at referral hospitals in DKI Jakarta Province in the period January 2020 to December 2022, totaling 166 patients. Each patient was followed for up to 11 months from the initiation of treatment, with final treatment outcomes collected through November 2023. Survival analysis using Cox proportional hazards regression was employed to assess the association between patient characteristics and time to UTO. Results: A total of 43.4% of patients is UTO. The cumulative probability of remaining free from UTO was 38% after day 400. Multivariate regression analysis showed that HIV-positive status (aHR = 2.98; 95% CI: 1.77–4.99) and comorbid diabetes mellitus (aHR = 1.92; 95% CI: 1.19–3.11) were significantly associated with an increased risk of UTO. Conclusion: UTO among MDR-TB patients on the short-term regimen remains high. HIV status and diabetes comorbidity are critical factors influencing treatment outcomes and should be prioritized in clinical management strategies for MDR-TB.
The Combination Diagnostic Test for Tuberculosis Screening in HIV Patients in Referral Hospitals in Indonesia Murtiani, Farida; Rosamarlina, Rosamarlina; Purnama, Asep; Farhanah, Nur; Utama, Made Susila; Agustin, Heidy; Sarif, Armaji Kamaludi; Widiantari, Aninda Dinar; Hasugian, Armedy Ronny
Public Health of Indonesia Vol. 11 No. 3 (2025): July - September
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i3.1094

Abstract

Background: Screening tests are needed to help screen suspected Tuberculosis (TB) pulmonary with HIV positive. With the limitation of specificity of the screening test and the need for combination with laboratory tools to increase that, a combination with standard examination is still needed, especially for limited healthcare facilities. Objective: This study aimed to determine Pulmonary TB screening tests with Human Immunodeficiency Syndrome (HIV) positive. Method: This observational study with a cross-sectional design was conducted in four government hospitals. Study subjects were inpatients and outpatients who met study inclusion criteria (> 14 years of age, HIV positive based on HIV test results, had clinical symptoms of episodic history of fever, and volunteered to take part in the study). Total subjects were 193 people, with episodic history of fever from <24 hours to 120 hours. Result: This study assessed a subject's clinical manifestation, physical examination and X-ray test. The “Night Sweat”, Infiltrates in the Upper Lobe”, “Enlargement of Lymph Nodes and “Left Rhonchi” and their combination have a sensitivity of>85%. Still, only the complete combination has a specificity of> 70%. The combination of “Night Sweat + Enlargement of Lymph Nodes + Left Rhonchi + Infiltrates in the Upper Lobe” and then “Enlargement of Lymph Nodes + Left Rhonchi + Infiltrates in the Upper Lobe” can be an alternative for screening Pulmonary TB-HIV positive with history of fever. Conclusion: Pulmonary TB screening in HIV patients with a history of fever can be used by completely combining clinical manifestation, physical examination, and X-ray. the variables "Night Sweat, Enlarged Lymph Nodes, left rhonchi breath sounds and pulmonary upper lobe infiltrates" in a gradual manner. Keywords: Diagnostic Combination Test; HIV-Tb Coinfection; Tuberculosis Screening; Clinical Manifestations in TB-HIV; Pulmonary TB in HIV Patients
Effectiveness of in-Tray Early Waring System Training on Knowledge and Practice of Nurses Nuraidah, Nuraidah; Widiantari, Aninda Dinar; Maemun, Siti; Hutabarat, Veronika; Khamid, Abdul; Wahyuning, Indah; Sumaryati, Sumaryati; Ambarwati, Desi; Murtiani, Farida
Indonesian Journal of Global Health Research Vol 6 No 5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i5.3367

Abstract

Death marks the conclusion of the disease trajectory. Prevention of fatality in patients facing acute and chronic diseases requires the competence of reliable health workers, with nurses playing a crucial role in delivering proficient care. Aiming for early detection of patients' clinical deterioration, nurses use an early warning system. Objective: to determine the effectiveness of EWS training in-tray method on knowledge and practice of EWS. We conducted a quasi-experimental study using one group pretest-posttest without a control group. The sample of this study was 70 executive nurses with consecutive sampling techniques. The research was held at the Inpatient Installation of Sulianti Saroso Infectious Disease Hospital (SSIDH) in June 2023. Observation sheets were utilized to assess Early Warning System (EWS) practices, and we employed valid and reliable questionnaires to gather information on respondents' knowledge. We performed univariate analysis using frequency distribution and bivariate analysis using the Wilcoxon test. Most respondents were in the late adult category (52.9%), female (80.0%), graduate Diploma III in nursing education (54.3%), and the most working period of 5 years (78.6%). The knowledge of participants increased significantly from 7.00 (2.00-13.00) (pretest) to 11.50 (5.00-20.00) (posttest) (p-value = 0.000). There was an increase in nurses' EWS knowledge and practice (p-value <0.05). Efforts to improve nurse competence in caring for patients with critical conditions are necessary. This can be achieved through coaching and regular training with the priority target of implementing nurses in the intensive care room.
Effectiveness of Ginger Drink (Zingiber Officinale Var Rubrum) on Reducing Nausea and Vomiting in Trimester I Pregnant Women Wahyuni, Ika; Herawati, Ita; Widiantari, Aninda Dinar; Murtiani, Farida
Indonesian Journal of Global Health Research Vol 6 No 6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i6.3794

Abstract

Nausea and Vomiting of Pregnancy (NVP) can become hyperemesis gravidarum thereby increasing the risk of pregnancy disorders. Ginger is an herbal plant that has long been known to prevent nausea and vomiting. The Aim study to determine the effectiveness of giving ginger drink (zingiber officinale var rubrum) to reduce nausea and vomiting in first trimester pregnant women. Quasi Experiment Research with the design used is One Group Pretest-Post Test Design. The sample in this study was the first trimester pregnant women at the Pratama Clinic Yardi Prima Tambun Bekasi as many as 33 mothers who were taken by purposive sampling. The intervention was carried out by giving 2.5 grams of white ginger sliced and brewed with 250 ml of warm water plus 10 grams of sugar (1 tablespoon) taken 2x1 a day for 4 days. Data were obtained by observing and measuring Nausea and Vomiting using the PUQE-24 instrument. Data analysis was univariate and bivariate with dependent T-test. The average Puqe-24 score before the ginger intervention was 9.79 and most of them were in the category of moderate nausea and vomiting as many as 23 (69.7%). The average emesis score after giving ginger was 6.64 and most of them were in the category of mild 14 (42.4%) and 2 (6.1%) not nausea and vomiting. There is an effect of giving ginger (zingiber officinale var rubrum) to mothers with NVP with P value (0.000) <α (0.05). Ginger is effective in reducing emesis gravidarum.
The Effect of Moringa (Moringa Oleifera L.) Leaf Extract Capsules in Increasing Hemoglobin Levels in Adolescent Girls Mauliku, Novie; Darmawan, Flora Honey; Yuliana, Hana; Murtiani, Farida; Norma, Norma
Indonesian Journal of Global Health Research Vol 7 No 1 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i1.4293

Abstract

Moringa leaves can be an alternative to increase hemoglobin (hb) levels because they contain high iron, protein, and vitamin C. Adolescent girls have a higher risk of experiencing anemia due to increased iron requirements resulting from menstruation. Objective: To determine the effect of moringa leaf extract capsules (Moringa Oleifera L) on increasing hemoglobin levels in teenage girls at SMKN 1 Takokak, Cianjur Regency. Method: The research design employed in this study is a pre-experimental approach, utilizing a one-group pretest-posttest design. The sample size consists of 30 adolescent girls selected through purposive sampling technique. Data collection involves measuring hemoglobin levels. Data analysis is conducted through univariate and bivariate analyses using the Wilcoxon Signed Rank Test. Results: The research findings indicate that there was an increase in hemoglobin levels before (10.69) and after (12.78) the intervention, with an average difference of -2.09. Furthermore, there was a significant p-value of 0.001 (<0.05). Conclusions: The moringa leaf extract capsules have shown an influence in increasing the hemoglobin levels of adolescent girls. Moringa Leaf Extract can be recommended as a non-pharmacological alternative to enhance hemoglobin levels.
Comparison of the Effectiveness of Two Levels of Suction Pressure on Oxygen Saturation in ARDS Patients Heryandi, Dadang; Sahrudi, Sahrudi; Pujiantana, Artetha Mutiara; Norma, Norma; Murtiani, Farida
Indonesian Journal of Global Health Research Vol 6 No S6 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS6.4655

Abstract

Patients in the Intensive Care Unit (ICU) often require mechanical ventilators, necessitating close monitoring and care, including regular evaluations of oxygen saturation levels. Suction procedures are conducted in the ICU to maintain airway patency, reduce sputum retention, and prevent pulmonary infections. The effectiveness of suction procedures can vary based on the suction pressure applied, which may impact patient outcomes differently. The purpose of this study was to determine the effectiveness of suction action with pressures of 130 mmHg and 140 mmHg on increasing oxygen saturation in ARDS patients with mechanical ventilation in the ICU. The research employed a quantitative approach using a quasi-experimental pre-post design with a control group. A sample of 30 ICU patients was divided into two groups: one group of 15 patients received suctioning at a pressure of 130 mmHg, while the other group of 15 received suctioning at 140 mmHg. Oxygen saturation levels were measured using pulse oximetry before and after the suction intervention. The procedures were conducted in accordance with the hospital's Standard Operating Procedure (SOP). Data were analyzed univariate and bivariate using the T-test. There was a significant increase in oxygen saturation after suctioning with both pressures. For the 130 mmHg group, the average increase in oxygen saturation was 5.933 with a P-value of 0.000. For the 140 mmHg group, the average increase was 6.400 with a P-value of 0.000. However, there was no statistically significant difference between the two suction pressures in terms of the overall increase in oxygen saturation, with a P-value of 0.567. Both 130 mmHg and 140 mmHg suction pressures were effective in improving oxygen saturation in ARDS patients on mechanical ventilation in the ICU. Hospitals should ensure structured and consistent monitoring of suction procedures in accordance with hospital SOPs to optimize patient outcomes.
Implementasi Teknik Clapping pada Anak Prasekolah dengan Pneumonia: Studi Kasus Darmawan, Dadang; Andriyani, Septian; Rahmi, Upik; Putri, Suci Tuty; Fitriana, Lisna Anisa; Malisa, Novi; Setiawan, Guling; Apriany, Dyna; Norma, Norma; Murtiani, Farida
Jurnal Penelitian Perawat Profesional Vol 6 No 6 (2024): Desember 2024, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v6i6.4657

Abstract

Pneumonia masih menjadi penyebab kematian yang signifikan, terutama pada anak usia prasekolah. Kondisi ini terjadi karena adanya penumpukan patogen di dalam alveoli yang menyebabkan terbentuknya eksudat inflamasi. Penelitian ini bertujuan untuk mengevaluasi intervensi clapping pada ana kusa prasekolah dengan pneumonia. Penelitian ini dirancang sebagai studi kasus dengan menggunakan pendekatan deskriptif kualitatif. Pengumpulan data dilakukan dengan wawancara, pemeriksaan fisik, observasi, dan analisis dokumentasi penelitian. Penelitian kami menghasilkan temuan yang signifikan yang menunjukkan efektivitas teknik clapping dalam membersihkan saluran napas, mengurangi akumulasi dahak, meningkatkan difusi gas, dan meringankan beban pernapasan. Teknik clapping sebagai salah satu komponen dari fisioterapi dada, memiliki potensi untuk diterapkan dalam intervensi penanganan pneumonia pada anak-anak.
PENGARUH TINDAKAN SUCTION PADA PERUBAHAN SATURASI OKSIGEN PADA PASIEN PNEUMONIA Yogasara, Yoseph; Rakhmawati, Arifah; Murtiani, Farida; Widiantari, Aninda Dinar
Jurnal Ilmiah Keperawatan IMELDA Vol. 9 No. 2 (2023): Jurnal Ilmiah Keperawatan IMELDA
Publisher : Program Studi S1/DIII-Keperawatan Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jikeperawatan.v9i2.1241

Abstract

ICU patients who use mechanical ventilators need intensive monitoring including blood gas analysis which contains oxygen saturation (SpO2). Suctioning is performed to clear airway, reduce sputum retention and prevent lung infection in advance. We studied effect of suctioning on oxygen saturation in pneumonia patients who used mechanical ventilator. This research was a quasi-experimental research with one group pretest-posttest design. We investigated 30 intensive care unit patients. Intervention was suctioning in semifowler position. Oxygen saturation was measured with pulse oximetry. Results showed that average oxygen saturation before intervention was 94,87% while after intervention was 96,93%. We performed Wilcoxon test and obtained p-value = 0.001. It concluded that suction affects oxygen saturation in pneumonia patients on ventilators in the ICU RSPI Sulianti Saroso with an average increase of 2.067%.
Co-Authors Abdul Khamid, Abdul Achmad Shidiq, Achmad Adria Rusli, Adria Afrina, Yeni Agustin Agustin Agustin, Heidy Aliza, Nur Ambarwati, Desi Amin, Desrinawati Muhammad Apriliani, Isnawati Armedy Ronny Hasugian Aryanto, Dara Tyas Putri Asep Purnama, Asep Asri C. Adisasmita Ciuputri, Pauline Dadang Darmawan Darmawan, Flora Honey Dinar Widiantari, Aninda Djajaningrat, Husjain Dyna Apriany Endang Sri Roostini Hardjolukito Fitri Nurhayati Fitri, Desi Yulia Fitrianur Laili, Fitrianur Hadayna, Saila Hana Yuliana Hanum, Sitti Fatimah Harimat Hendarwan Hendrawati, Nunung Herawati, Ita Herlina Herlina Heryandi, Dadang Hutabarat, Veronika Ika WAHYUNI Indawati, Eli Jahiroh, Jahiroh Kunti Wijiarti, Kunti Kusmardi Kusmardi Lisna Anisa Fitriana, Lisna Anisa Maemun, Siti Maryani Maryani Matondang, Faisal Mauliku, Novie Mieska Despitasari Mochammad Hatta Mochartini, Tri Muhammad Atoillah Isfandiari Nina Mariana, Nina Norma Norma Novi Malisa, Novi Nugroho, Anita Puspitasari Dyah Nur Farhanah, Nur Nuraidah Nuraidah, Nuraidah Nurhayati Nurhayati PERTIWI, INTAN Pratiwi, Tiara Z. Pujiantana, Artetha Mutiara Purnama, Tri B. Rahmawani, Atika Rakhmawati, Arifah Rivaldiansyah, Rivaldiansyah Rizana Fajrunni’mah rosamarlina, rosamarlina Sahrudi, Sahrudi Saputra, Mohamad Hendra Sarif, Armaji Kamaludi Septian Andriyani, Septian Setianingsih, Tri Yuli Setiawan, Guling Suci Tuty Putri, Suci Tuty Sudarto Ronoatmodjo Suliati Suliati Sumaryati Sumaryati Syafendra, Mega Oktariena Tampubolon, Maria L. Tanjungsari, Dian W. Tanjungsari, Dian Wahyu Titi Sundari Upik Rahmi, Upik Utama, Made Susila Vivi Setiawaty Wahyuning, Indah Wasilah Wasilah Widiantari, Aninda D. Widiantari, Aninda Dinar Wirasmi, Sundari Yoenoes, Dedet Hidayati Yogasara, Yoseph Yulianto, Aris