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Journal : Journal Health Applied Science And Technology (JHAST)

KOLERASI JUMLAH LEUKOSIT TERHADAP KADAR CRP PADA PENDERITA PENYAKIT TUBERKULOSIS Bastian Darwin; Meyrita Birka Yolanda
jurnal kesehatan terapan sains dan teknologi Vol 1 No 1 (2023): Journal Health Applied Science And Technology (JHAST)
Publisher : IKesT Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52523/jhast.v1i1.1

Abstract

Introduction: Tuberculosis is one of the most common infectious diseases in the community with a percentage of 80% caused by Acid Resistant Bacillus (BTA), namely the bacterium Mycobacterium tuberculosis. Leukocytes act as an immune system or kill germs and diseases that are in the human bloodstream. In addition to leukocytes, there are CRP parameters that help fight tuberculosis infection, namely by releasing various pro-inflammatory cytokines and bacterial invasion occurs which then induces liver cells to synthesize acute phase proteins such as CRP which will increase sharply for a few moments, inflammation will occur during the systemic inflammatory process. Purpose: This study aims to determine the correlation between leukocyte count and CRP levels in tuberculosis patients. Research Method: This research was conducted in the Hematology Laboratory of the Muhammadiyah Palembang Institute of Health Sciences and Technology in March-April 2021. This type of research is Analytical Descriptive research with a cross sectional approach. Data were analyzed using Spearmen's correlation test. Results: This study had an average leukocyte count of 4.85 cells/µL, CRP examination results with an average value of 9.60 mg/L and Spearman's correlation test with p = 0.113. Conclusion: There is no correlation between leukocyte count and CRP levels in tuberculosis patients.
Perbedaan Kadar Hemoglobin Segera Diperiksa dan Penundaan 2,5 Jam Pada Suhu Ruang Indah Sari; Ema Karlina; Bastian
jurnal kesehatan terapan sains dan teknologi Vol 1 No 1 (2023): Journal Health Applied Science And Technology (JHAST)
Publisher : IKesT Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52523/jhast.v1i1.5

Abstract

Hemoglobin is a protein molecule in red blood cells that functions as a means of transporting oxygen (O2) from the lungs to tissues throughout the body and taking carbon dioxide (CO2) from the tissue below to the lungs to be released into the free air. This study aims to determine the effect between blood immediately examined and a delay of 2.5 hours at room temperature on hemoglobin levels conducted at IKesT Muhammadiyah Palembang. The type of research used is cross sectional with intact group comparison research design. The sample consisted of 30 samples immediately examined and 30 samples with a delay of 2.5 hours taken from 30 respondents. The study was conducted starting from patient preparation, taking examination materials, processing examination materials, analysis and research results. The average hemoglobin level immediately examined was 12.8 g/dL while the hemoglobin level with a delay of 2.5 hours was 12.7 g / dL, the results of the wilxocon test showed that the significant value was p=0.342. The p value obtained is p>0.05. The results can be concluded that there is no difference in hemoglobin levels immediately examined and a delay of 2.5 hours at room temperature.
Perbedaan Jumlah Trombosit Pada Teknik Pengambilan Darah Vena menggunakan Spuit Dan Vacumtainer Bastian Darwin; Aristoteles; Dewi Hartati
jurnal kesehatan terapan sains dan teknologi Vol 1 No 2 (2023): Journal Health Applied Science And Technology (JHAST)
Publisher : IKesT Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52523/jhast.v1i2.12

Abstract

Platelets are blood cells that play an important role in homepstatis. Platelets attach the endothelial layer of torn blood vessels (wounds) by forming a platelet plug. Platelets do not have a cell nucleus, measuring 1-4, and the cytoplasm is blue with purple-reddish granules. Platelets are derived from megakaryocytic, which are derived from the cytoplasm fragments of megakaryocytic. 150.000-350,000 platelets /ml of blood platelet granules contain blood clotting factors, Adenosine Diphosphate (ADP). Adenoxine Triphoxphate (ATP, calcium, serotonin, and catecholamines. Most of them play a role in stimulating the start of the blood clotting process. The lifespan of platelets in circulating blood is about 8-10 days. The purpose of this study was to determine differences in the number of platelets depending on the technique of taking venous blood using a syringe and a vacumtainer. The type of research used is cross sectional, which was carried out in the laboratory of Puskesmas Dempo on 05-01-2022. The sample used was EDTA blood. The number of samples studied was 30 samples with two treatments using a non-probability sampling technique. Based on the results of the examination of the number of platelets in the technique of taking venous blood using a syringe and a vacumtainer using the hematology analyzer, the average value for the syringe method was 353,27 /ml of blood and the vacumtainer method had an average value of 345,27 /ml 0f blood p= 0.612 was obtained from data analysis using the paired sample test. The conclusion of this study is that there is no difference between the number of platelets dependen on the technique of taking venous blood using a syringe and a vacum.
GAMBARAN PEMERIKSAAN TES CEPAT MOLEKULER (TCM) GENEXPERT PADA PASIEN DI RUMAH SAKIT UMUM DAERAH PALEMBANG BARI Bastian Darwin
jurnal kesehatan terapan sains dan teknologi Vol 2 No 1 (2024): Journal Health Applied Science And Technology (JHAST)
Publisher : IKesT Muhammadiyah Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52523/jhast.v2i1.39

Abstract

Background: Tuberculosis is an infectious disease caused by the bacterium Mycobacterium tuberculosis. The diagnosis of pulmonary TB is made based on the clinical picture, physical examination, radiological picture, laboratory examination, and tuberculin test. The pulmonary TB diagnosis currently used routinely in laboratories including hospitals and health centers is bacteriological diagnosis using the rapid molecular test (TCM) technique, while microscopic examination is used as a follow-up examination (monitoring) in patients receiving treatment. TCM examination is a molecular detection method based on nested real-time PCR. The use of TCM is a priority for TB testing because it has several advantages, including: it can diagnose TB and resistance to rifampicin quickly, accurately with high sensitivity, and results can be known in approximately 2 hours. Objectives: The aim of this study is to see the description of TCM examinations in patients at Palembang BARI Regional Hospital based on gender and age groups. Method: This research was conducted at the Palembang BARI Regional General Hospital Laboratory Installation. The samples taken were from patients at the Palembang BARI Regional General Hospital and not referrals from other health service facilities. 50 samples were taken and grouped based on TCM results, gender and age. Result: In grouping based on TCM results, the highest result was negative. In gender grouping, more male patients underwent TCM examinations. In the age grouping, the elderly are more likely to undergo TCM examinations. Conclusion: There are several factors that cause a person to become infected with TB, namely social status, smoking, and having the habit of drinking alcohol.