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Journal : Journal of Holistic and Traditional Medicine (JHTM)

NEW INNOVATION USING TOPICAL ITRACONAZOLS AS A SUPERFICIAL FUNGAL SKIN INFECTION THERAPY AND ITS SUPERIORITY COMPARED TO STANDARD THERAPY Tan, Sukmawati Tansil; Firmansyah, Yohanes
Journal of Holistic and Traditional Medicine Vol. 6 No. 02 (2021): Journal of Holistic and Traditional Medicine
Publisher : Perhimpunan Kesehatan Holistik Indonesia

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Abstract

Background: Fungal infection of the skin is a common clinical problem in the community, particularly in groups of people who practice poor hygiene or in populations with a low immune status. Microsporon audoinii and Trichophyton rubrum, can cause the disease to be chronic and residif. This is generally due to the fungus developing a mechanism of resistance to the commonly used drug regimens in the community. As a result, a novel innovation is required to expedite patients' healing from dermatophytosis. Method: The purpose of this study is to compare the efficacy of a new treatment therapy utilizing a combination of 2% itraconazole, 1% salicylic acid, and 2% sulfur to that of 2% ketoconazole (standard therapy). The samples for this study were all cases of fungal infections of the skin diagnosed at Indra's clinic between 2016 and 2017. The study's independent variable was the formulation of the drug, while the dependent variable was clinical improvement and the occurrence of side effects. Results: The cure rate was 91,7 percent for the 121 respondents who received a combination cream containing 2% itraconazole, and 80.7 percent for the 114 respondents who received a ccream containing 2% ketoconazole. There were no statistically significant differences in adverse events between the two intervention groups. Finally, Innovative drug formulations for fungal infections (2 percent itraconazole, 1% salicylic acid, and 2% sulfur) have been shown to be more effective and superior to standard therapy.
FROM LABORATORY TO CLINICAL - TREATMENT OF HYPERPIGMENTATION POST-INFLAMMATORY, ANTI-MICROBA AND BODY ODOR IN AXILLARY REGION WITH TISSUE INNOVATION COMPOSITED PIONIN, ALOE VERA, GLUTATHIONE, AND LAVENDER Tan, Sukmawati Tansil; Firmansyah, Yohanes
Journal of Holistic and Traditional Medicine Vol. 6 No. 02 (2021): Journal of Holistic and Traditional Medicine
Publisher : Perhimpunan Kesehatan Holistik Indonesia

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Abstract

It is generally recognized that hyperpigmentation post-inflammatory and body odor issues can be distressing. This will also have an effect on the overall quality of life. As a result, we require a therapy that may address both post-inflammatory hyperpigmentation and body odor issues. The goal of this study was to see if the invention's combination had any antibacterial properties, as well as if it might lessen or fade the signs of hyperpigmentation post-inflammatory. It is believed that the antibacterial action of the current innovation would minimize patients' body odor. This composition is in accordance with the Regulation of the Head of the Drug and Food Control Agency of the Republic of Indonesia Number 12 of 2019 concerning Contaminants in Cosmetic. The axillary tissue cleansing formulation comprises pionin, aloe vera, glutathion, and lavender, all of which have been shown in the laboratory to prevent bacterial development. Clinically, however, the administration of this intervention was demonstrated to be capable of reducing or fading the symptoms of hyperpigmentation post-inflammatory and relieving body odor with very little adverse effects.