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Journal : Jurnal Penelitian Pendidikan IPA (JPPIPA)

Review of Essential Oil Bioactivity Against Anxiety Symptom Prambudi, Hery; Supriyatin
Jurnal Penelitian Pendidikan IPA Vol 11 No 6 (2025): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i6.11512

Abstract

The use of essential oils as complementary therapy for various health conditions, especially those involving the central nervous system (CNS), is gaining increased attention. Anxiety disorder, a common CNS-related condition characterized by excessive worry and fear, is one of the main targets for such therapies. Essential oils from various plants contain bioactive compounds that act on the CNS and exhibit anxiolytic potential. This systematic literature review aimed to assess the anxiolytic bioactivity of essential oils and identify the most effective types used for anxiety reduction. Preclinical studies from seven journals revealed that essential oils such as Agarwood, Bergamot, Cananga odorata, Ocimum basilicum, Lavender, Nectandra grandiflora, and Cinnamon influence animal behavior linked to anxiety reduction. Clinical reviews from eleven studies found that Lavender oil, especially due to its linalool content, was the most commonly used essential oil for lowering anxiety levels. The mechanisms include inhibition of CRF, ERK1, and CREB, antagonism of NMDA receptors, inhibition of SERT, and modulation of GABA<sub>A</sub> receptors and calcium influx. In conclusion, essential oils exhibit various bioactivities affecting the CNS, supporting their role as potential anxiolytic agents.
Detection of Formalin in Salted Squid Using Dragon Fruit Peel Extract (Hylocereus polyrhizus) Supriyatin; Prambudi, Hery
Jurnal Penelitian Pendidikan IPA Vol 11 No 7 (2025): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i7.11425

Abstract

This research aims to determine the presence of salted squid sold at the Main Jatibarang market in Indramayu using dragon fruit peel extract, determine the level of formaldehyde in the samples and whether there is a difference when using dragon fruit peel extract and chromatophic acid in detecting formaldehyde in salted squid. The research method used in this research is descriptive comparative, while the qualitative examination method uses dragon fruit peel extract, chromatophic acid and for quantitative examination the chromatophic acid method uses a UV-Vis spectrophotometer. Data analysis uses univariate analysis in SPSS and describes the results descriptively. The results of qualitative tests or qualitative detection of formalin using dragon fruit peel extract and chromatogenic acid obtained the same results, namely 5 (five) positive samples in the same sample. Qualitative results show that there is no difference in positive results from two different methods for detecting formalin. Meanwhile, quantitative tests using a UV-Vis spectrophotometer with a wavelength of 570nm resulted in samples D1 having a concentration of 7.22ppm, D2 having a concentration of 7.25ppm, D3 having a concentration of 6.77ppm, D4 having a concentration of 6.76ppm, and D5 having a concentration of 6.72ppm.