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All Journal Journal of Food and Pharmaceutical Science Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kesehatan Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Penelitian Kesehatan Suara Forikes Jurnal Penelitian Pendidikan IPA (JPPIPA) Media Kesehatan Politeknik Kesehatan Makassar JURNAL FARMASIMED (JFM) Amalee: Indonesian Journal of Community Research & Engagement Jurnal farmasi UIN Alauddin Makassar Yumary: Jurnal Pengabdian kepada Masyarakat Journal of Experimental and Clinical Pharmacy (JECP) Jurnal EduHealth Medical Sains : Jurnal Ilmiah Kefarmasian Journal Of Human And Education (JAHE) Pharmacology And Pharmacy Scientific Journals (PAPS Journals) Jurnal Katalisator Nusantara Scientific Medical Research Journal Journal of Food and Pharmaceutical Sciences Majority Science Journal Jurnal Medika: Medika Medical Sains : Jurnal Ilmiah Kefarmasian
Nurhikma Awaluddin
Fakultas Farmasi, Universitas Megarezky Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Journal : Media Kesehatan Politeknik Kesehatan Makassar

 1 
FORMULATION AND ANTIBACTERIAL ACTIVITY TEST OF HAND SANITIZER ETHANOL EXTRACT OF BASIL (Ocimum Sanctum. L) AGAINST Escherichia coli dan Streptococcus Aureus Nurfiddin Farid; Nurhikma Awaluddin; Suhartina Hamzah; Muhammad Yusuf; Rahmania Rahmania
Media Kesehatan Politeknik Kesehatan Makassar Vol 15, No 2 (2020): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v15i2.1764

Abstract

Basil leaves (Ocimum sanctum L) Against to inhibit the growth of Escherichia coli and Staphylococcus aureus bacteria to increase its effectiveness, it is made in practical and easy-to-use preparations. One of the effective dosage forms for topical use is Hand Sanitizer. The factor that influences the quality of gel preparations is Carbopol as a gelling agent. To know the antibacterial effect and ethanol extract concentration of basis leaves (Ocimum sanctum L). preparation of Hand sanitizer, in which the selection and type of carbopol concentration will determine the stability of the gel formed. Basil leaf extract was obtained by maceration method using 96% ethanol solvent. The product is formulation in the form a gel Hand sanitizer with the addition of carbopol as a gelling agent with a concentration of 1,5% this type of research is  laboratory Experiment with Stability Test, Organoleptic Test, pH, Homogeneity and Scattering power and Antibacterial Test on Escherichia coli and Staphylococcus aureus. For testing antibacterial activity the method used is the diffusion method. Form the research results obtained antibacterial Hand sanitizer preparations with concentration of 1%, 3% and 5%  showed changes in odor , color and shape before and after storage at pH 4,8- 6,4. Organoleptic  testing showed no changes in odor, color and shape before and after accelerated storage. pH testing shows charges before and after storage are caused by temperature light factors. Homogeneity testing showed no changes before and after storage. Scatter tests indicate changes before and after storage caused by temperature light factors. Antibacterial activity test shows that the formulation of Hand sanitizer ethanol extract of basil leaves (Ocimum sanctum L) with a concentration of 1%, 3% and 5%. can inhibit the growth of Escherichia coli and Staphylococcus aureus with Medium -Strong inhibitory zones. From the results of research conducted it was concluded that the antibacterial Hand sanitizer ethanol of basis was physically and chemically stable for Organiletic, pH, Homogeneity and Scattering effects.
PROFIL PENGGUNAAN ANTIHIPERTENSI PADA PASIEN PRE EKLAMPSIA DI RUMAH SAKIT Akbar Awaluddin; Ismah Mahmud; Nurhikma Awaluddin; Maulita Indrisari
Media Kesehatan Politeknik Kesehatan Makassar Vol 16, No 2 (2021): Media Kesehatan
Publisher : Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/medkes.v16i2.2269

Abstract

Pre-eklampsia merupakan hipertensi yang ditandai dengan meningkatnya tekanan darah yakni ≥140/90 mmHg, terjadi setelah kehamilan berusia 20 minggu dan kebanyakan kasus ditegakkan dengan adanya proteinuria. Disertai dengan sakit kepala, kelainan pada penglihatan, nyeri dada serta dyspnea. Penelitian memiliki tujuan untuk mengetahui jenis antihipertensi yang dipergunakan untuk pasien pre-eklampsia di Rumah Sakit Umum Daerah Latemmamala Soppeng periode April 2020-Maret 2021, karena didasari oleh fakta tingginya kematian akibat hipertensi kehamilan serta bervariasinya terapi yang diberikan. Data dikumpulkan secara retrospektif yaitu pengambilan data rekam medis pre-eklampsia, berupa data karakteristik pasien (usia pasien, usia kehamilan), tekanan darah, diagnosa, hasil laboratorium berupa kadar proteinurea dan data pengobatan antihipertensi (jenis obat, dosis obat, frekuensi penggunaan obat). Dari hasil penelitian, didapatkan terapi antihipertensi yang digunakan pada pasien pre-eklampsia yaitu CCB dengan persentase 46,15%, diuretik sebanyak 3,84%, kombinasi antihipertensi sebanyak 34,58%. Berdasarkan hasil penelitian, ditarik kesimpulan profil antihipertensi yang digunakan untuk pasien pre-eklampsia di Rumah Sakit Umum Daerah Latemmamala Soppeng yaitu menggunakan obat golongan CCB sebagai antihipertensi terbanyak. Yang dimana berdasarkan literatur, nifedipin termasuk terapi lini yang pertama untuk digunakan pada penanganan pre-eklampsia.
Co-Authors - Sri Prilmayanti Awaluddin, - Aadilah, Aadilah Adhelia, Dhea Handa Akbar Awaluddin Akbar Awaluddin Akbar Awaluddin Alydrus, Nur Laela Alyidrus, Rugayyah Alyidrus, Rugayyah Andi Meinar Dwi Rantisari Thayeb Andi Ulfiana Utari Andriawan, Riki Arafah Nurfadillah Awaluddin, Akbar Awaluddin, Akbar Awaluddin, Sri Wahyuni Farid, Nurfiddin Fawzy, Nabiyl Ahmad Hamka Hanfirs, Rahmatia Inda Andriani Ismah Mahmud Junita, Nurfitria Mahasakti, M Tri Budi Maulita Indrisari, Maulita Muhammad Yusuf Muntasir, Muntasir Nadjamuddin, Mirfaidah Nasrawati Basir Ni Luh Gebi Parwati Nur Pebrianti Caronge Nurani Nurani Nurjannah Bachri Nurjannah Bachri Rahmania Rahmania Ramadhani, Rezki Rustam, Julaiha Sadsyam, Sriyanty Santi, Elvira Sella Septiyani Mointi Selviana Sirajul Firdaus, Sirajul Sri Wahyuni Awaluddin Sri Wahyuni Awaluddin Sri Wahyuningsih Sri Wahyuningsih Sriyanty Sadsyam St. Rahmadani Suharniayanti, Suharniayanti Suhartina Hamzah Susanti Ngole Dhadu Syamsu, A. Suparlan Isya Tangden, Nopianti Thayeb, Andi Meinar Dwirantisari Ummu Kalsum Utari, Andi Ulfiana Wahid, Hilmiati wahyuni wahyuni Wahyuni, Wahyuni