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All Journal Majalah Kedokteran Bandung Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Berkala Ilmu Kesehatan Kulit dan Kelamin Majalah Kesehatan FKUB Molecular and Cellular Biomedical Sciences (MCBS) Majalah Kedokteran Nusantara The Journal Of Medical School Sumatera Medical Journal Jurnal Prima Medika Sains SCRIPTA SCORE Scientific Medical Journal Indonesian Journal of Global Health research Narra J Jurnal Pengabdian Masyarakat Kedokteran JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Eduvest - Journal of Universal Studies
Paramita, Deryne Anggia
Department Of Dermatology And Venereology, Faculty Of Medicine, Universitas Sumatera Utara, Medan
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Early-onset squamous cell carcinoma in xeroderma pigmentosum: A rare case Susanto, Claudia; Paramita, Deryne Anggia
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 16, No 1, (2025)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol16.Iss1.art16

Abstract

Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis characterised by photosensitivity, dry skin, pigmentary abnormalities, premature skin aging, and skin cancers at an early age. This case report aims to alert health professionals about this disease, considering the rarity of the disease and the need for an early diagnosis of patients with XP. A 4-year-old boy was referred to our department with multiple painful ulcerated masses over his head and face, which had developed over the past two years. At the age of 6 months, the patient started to develop hyperpigmented spots of numerous sizes on his face, and gradually spread to the other sun-exposed areas of his body. He also had dry skin, photophobia, redness, and watery eyes. Dermatological examination showed multiple ulcerated erythematous nodules at the temporal and frontotemporal region; multiple scaly, hyperpigmented macules, papules, and cutaneous horns at the facial region; multiple hypopigmented and hyperpigmented macules, generalised distributed, predominantly over the sun-exposed areas. A biopsy examination from one of the nodules showed keratinising squamous cell carcinoma (SCC). The patient was diagnosed with xeroderma pigmentosum and was treated with multidisciplinary assessment involving dermatology, paediatric, oncology surgery, ophthalmology, and otolaryngology. The diagnosis in this patient is made clinically based on history taking, physical examination, and confirmation of malignancy from biopsy. Early diagnosis of XP is crucial for decreasing the development of neoplasms, which could improve the patient’s quality of life.
Clinical Features and Histopathologic Examination in Supporting The Diagnosis of Exfoliative Dermatitis Suspected Caused by Captopril in Child : A case report Astarina, Awalia; Alferraly, T Ibnu; Paramita, Deryne Anggia; Nababan, Kristo A
Indonesian Journal of Global Health Research Vol 7 No 5 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i5.6870

Abstract

Exfoliative dermatitis (ED) is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body skin surface area. It is a reaction pattern and cutaneous manifestation of a myriad of underlying ailments, including psoriasis and eczema, or a reaction to the consumption of certain drugs. Though some experts believe it does not pose a significant risk of death, erythroderma is a potentially life-threatening condition that requires proper diagnosis, identification of underlying etiology, and management. Several factors have been implicated as triggers for erythroderma and can be grouped into several general categories, including preexisting dermatoses, drugs, and malignancies. Drugs Involved in ED, one of the drugs that cause it is cardiac drugs such as captopril. Captopril, an angiotensin-converting enzyme (ACE) inhibitors containing a sulfhydryl group and has occasionally been implicated in complex immunological diseases, this chemical group has been considered the culprit of allergic reactions to captopril. Histopathologic examination is important to exclude differential diagnosis. Management of ED involves combining symptomatic relief with addressing the underlying etiology and potential systemic complications. In patient hospitalization is required in acute cases.
Case Report: Suspected Thiamphenicol-Induced Stevens-Johnshon Syndrome-Toxic Epidermal Necrolisis Overlap in A Child – Diagnosis and Management Apriano, Ika Diamanda; Paramita, Deryne Anggia; Nababan, Kristo Alberto
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6523

Abstract

Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are rare delayed-type hypersensitivity reactions characterized by detachment of the epidermis and mucous membranes, along with skin necrosis. While these conditions are rare in children, they are most commonly caused by antibiotics, antiepileptic drugs, and antipyretic drugs. This case report aims to highlight thiamphenicol as a rare and potentially overlooked cause of SJS/TEN in pediatric patients. A 14-year-old girl who developed painful red patches accompanied by fluid-filled blisters on almost her entire body which appeared five days after taking the antibiotic thiamphenicol. The patient also experienced red, watery eyes; blisters on the lips and oral cavity; involvement of the nipples; and was unable to swallow due to severe pain in the mouth and throat. The patient was diagnosed with SJS-TEN overlap, and showed a good response to systemic corticosteroids (methilprednisolone) and supportive therapy. Her overall prognosis was favorable, with a Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) score of 1. The management of SJS/TEN involves a multidisciplinary specialist approach, immediate withdrawal of the suspected drug, administration of corticosteroids, and comprehensive supportive care.
Gambaran Tingkat Pengetahuan dan Pemilihan Pengobatan Ketombe pada Mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Sriwulan, Anyelin; Dalimunthe, Dina Arwina; Paramita, Deryne Anggia; Widjaja, Sry Suryani; Samosir, Fauzan Azmi Hasti Habibi
SCRIPTA SCORE Scientific Medical Journal Vol. 4 No. 2 (2023): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v4i2.10495

Abstract

Latar Belakang. Ketombe merupakan gangguan kulit kepala yang ditandai dengan pengelupasan abnormal pada kulit kepala. Ada tiga penyebab utama yang menimbulkan ketombe yaitu jamur Malassezia, sekresi kelenjar sebasea, dan sensitivitas individu. Berbagai macam pengobatan telah banyak dilakukan untuk mengatasi masalah ketombe. Tujuan. Untuk mengetahui tingkat pengetahuan dan pemilihan pengobatan ketombe pada mahasiswa Fakultas Kedokteran Universitas Sumatera Utara Angkatan. Metode. Penelitian ini bersifat deskriptif menggunakan metode pendekatan studi potong-lintang. Sampel penelitian merupakan mahasiswa Fakultas Kedokteran Universitas Sumatera Utara. Pengumpulan data menggunakan kuesioner yang disebarkan secara online melalui Google form dan QR Code. Hasil. Didapatkan mahasiswa memiliki pengetahuan yang baik tentang ketombe (92,1%). Berdasarkan pemilihan pengobatan ketombe, sumber informasi didapatkan melalui media elektronik (84,2%), tempat membeli obat di swalayan/mal (72,6%), cara memilih pengobatan ketombe hanya menggunakan sampo saja (63,7%), faktor pemilihan pengobatan ketombe karena mudah didapatkan (71,1%), alasan pemilihan pengobatan ketombe karena kandungan yang terdapat di dalam sampo sangat bagus (58,4%), bahan yang dipilih dalam pemilihan pengobatan ketombe menggunakan bahan alami dan bahan kimia (51,1%). Kesimpulan. Tingkat Pengetahuan mahasiswa baik tentang ketombe. Berdasarkan pemilihan pengobatan ketombe, sumber informasi yang paling banyak didapatkan responden melalui media elektronik, tempat responden membeli obat paling banyak di swalayan/mal, cara responden dalam memilih pengobatan ketombe paling banyak hanya menggunakan sampo, faktor pemilihan pengobatan ketombe responden paling banyak karena mudah didapatkan, alasan pemilihan pengobatan ketombe responden paling banyak karena kandungan yang terdapat dalam sampo sangat bagus, bahan yang dipilih responden dalam pemilihan pengobatan ketombe paling banyak menggunakan bahan alami dan bahan kimia.
Relationship Between Skin Hydration Levels With The Severity of Diaper Dermatitis in Children Aged 0-24 Months Gabriella Manurung, Widya; Anggia Paramita, Deryne; Nababan, Kristo A.
Eduvest - Journal of Universal Studies Vol. 5 No. 1 (2025): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i1.33273

Abstract

Diaper dermatitis is a common dermatological condition in children, particularly those aged 0-24 months, characterized by mild to severe inflammation. Over hydration skin has been associated with the occurrence of diaper dermatitis, as it can disrupt the skin barrier and trigger inflammation. To determine the relationship between skin hydration levels and the severity of diaper dermatitis in children aged 0-24 months. A cross-sectional study was conducted on 87 children aged 0-24 months with diaper dermatitis. Skin hydration levels were measured using a Corneometer® CM 825. The severity of diaper dermatitis was assessed using the Buckley Scale. Data analysis used the Chi-Square test, and results were considered significant if p<0,05. The relationship between the level of skin hydration and the severity of diaper dermatitis showed significant results (p=0.034) where the majority of subjects had a sufficiently hydrated degree of skin hydration in the diaper area, which was 69 people. Skin with sufficiently hydrated has a higher risk of more severe diaper dermatitis.
Penyuluhan Perawatan Kulit Bayi dan Anak pada Masyarakat Desa Buluh Cina, Kecamatan Hamparan Perak, Deli Serdang Paramita, Deryne Anggia; Effendy, Elmeida; Rahmawaty, Rodiah; Wahyuni, Arlinda Sari; Amin, Mustafa Mahmud; Hamdi, Ibnati Amira; Afia, Nadira
Jurnal Pengabdian Masyarakat Kedokteran Vol 5, No 1 (2026): January
Publisher : Fakultas Kedokteran, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/abdimasku.5.1.30-37

Abstract

Salah satu isu penting yang diangkat dalam pembangunan kesehatan di Provinsi Sumatera Utara adalah kesehatan kulit bayi dan anak, mengingat kelompok usia ini memiliki karakteristik kulit yang berbeda dibandingkan orang dewasa, yakni lebih tipis, sensitif, dan rentan terhadap berbagai gangguan seperti iritasi, ruam popok, biang keringat, dan infeksi kulit. Kurangnya pemahaman orang tua dan pengasuh mengenai perawatan kulit yang benar sering menjadi faktor utama munculnya permasalahan tersebut. Berdasarkan data global dan nasional, prevalensi penyakit kulit pada anak cukup tinggi, di antaranya dermatitis atopik (10–20%) dan ruam popok (sekitar 25%), dengan faktor lingkungan dan kebersihan sebagai penyebab dominan. Kegiatan pengabdian ini bertujuan untuk meningkatkan pengetahuan masyarakat mengenai perawatan kulit bayi dan anak melalui penyuluhan kesehatan dan konsultasi langsung. Metode yang digunakan meliputi edukasi interaktif, sesi tanya jawab, serta pelaksanaan pra-uji dan pasca-uji untuk menilai peningkatan pemahaman peserta. Hasil kegiatan diharapkan menunjukkan peningkatan signifikan dalam pengetahuan masyarakat tentang pentingnya menjaga kesehatan kulit, faktor risiko yang memengaruhi, serta praktik perawatan yang tepat. Implikasi dari kegiatan ini adalah meningkatnya kesadaran dan kemampuan masyarakat dalam melakukan perawatan kulit bayi dan anak secara mandiri di rumah sehingga dapat menurunkan kejadian penyakit kulit serta meningkatkan derajat kesehatan anak di lingkungan setempat.
Unveiling harlequin ichthyosis beyond the neonatal period: A case from North Sumatra, Indonesia Manurung, Widya Gabriella; Paramita, Deryne Anggia; Nababan, Kristo Alberto
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 17, No 1, (2026)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol17.Iss1.art11

Abstract

Harlequin ichthyosis (HI) is a rare and life-threatening form of autosomal recessive congenital ichthyosis, typically diagnosed in the neonatal period due to its distinctive clinical features. We report a 7-year-old boy from North Sumatra, Indonesia, who survived well beyond infancy despite limited resources. He was born preterm at 35 weeks to consanguineous parents, with a history of a sibling who died in early infancy from a similar condition. The patient presented with ectropion, eclabium, underdeveloped ears, severe contractures, and generalized hyperkeratotic plaques with deep fissures. Clinical management focused on supportive dermatologic care, including twice-daily bathing, emollient application, topical antibiotics for erosions, and multidisciplinary referrals. Notably, the patient did not receive systemic retinoids or neonatal intensive care, yet the survival was achieved with minimal but consistent supportive measures. This case underscores the importance of early recognition of HI, the role of family history and consanguinity in clinical suspicion, and the potential for survival in resource-limited settings. It also highlights the profound psychosocial burden on affected families and emphasizes the need for genetic counselling to reduce recurrence in high-risk populations.
Relationship Between Nutritional Status and Hemodialysis Therapy in Patients With Chronic Kidney Disease at Adam Malik Medan Hospital, Indonesia Muhammad Siddik Nasution; Sumi Ramadani; Edy Ardiansyah; Deryne Anggia Paramita
Sumatera Medical Journal Vol. 8 No. 2 (2025): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v8i2.19070

Abstract

Background: One of the measures taken to control chronic kidney failure is through the hemodialysis procedure. Hemodialysis therapy can cause various side effects in patients, one of which is the risk of decreased nutritional status which can result in malnutrition. When the nutritional status of kidney failure patients worsens, the quality of life also decreases. Objective: This study aimed to determine the relationship between nutritional status and hemodialysis therapy at Haji Adam Malik General Hospital, Medan. Methods: This research was conducted from February to October 2024. This research is an analytical observational study using a cross sectional study design. The sample taken in this study was 80. Data was obtained from medical records at H. Adam Malik General Hospital, Medan. Results: The correlation test with the Chi-square test showed no relationship between Body Mass Index and several criteria, namely: Gender (p=0.645), age (p=0.410), creatinine (p=0.296), urea (p=0.296), albumin (p=0.315). Conclusion: There is no relationship between BMI and age, gender, albumin levels, creatinine levels and albumin levels in hemodialysis patients at H. Adam Malik General Hospital, Medan. The majority of patients undergoing hemodialysis at H. Adam Malik General Hospital Medan have a normal BMI (66%).
Co-Authors Afia, Nadira Alferraly, T Ibnu Andrew, Reynard Apriano, Ika Diamanda Astarina, Awalia Ayodhia P. Pasaribu, Ayodhia P. Butar Butar, Agatha Uli Angelica Dina Arwina Dalimunthe, Dina Arwina Edy Ardiansyah Elmeida Effendy Gabriella Manurung, Widya Hamdi, Ibnati Amira Hendri Wijaya, Hendri Khairina Nasution Kollins, Fini Kristina Kristina Nadeak Lubis, Andriamuri Primaputra Lubis, Inke ND. Lubis, Nenni Dwi Aprianti Manurung, Widya Gabriella Muhammad Ikhfa Yusril Bahari Muhammad Siddik Nasution Mustafa Mahmud Amin Nababan, Kristo A Nababan, Kristo A. Nababan, Kristo Alberto Nasution, Afrida Aryani Nasution, Fitriyani Nova Zairina Lubis Puteri Wulandari Putri Amelia Rahmawaty, Rodiah Restuti Hidayani Saragih Richard Hutapea Richard Hutapea Rita Evalina Samosir, Fauzan Azmi Hasti Habibi Sinaga, Adinda Alleyda Sriwulan, Anyelin Suherman, Jessen Sumi Ramadani Susanto, Claudia Syahril Rahmat Lubis Wahyuni, Arlinda Sari Widjaja, Sry Suryani Yoan Carolina Panggabean