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All Journal Ensiklopedia of Journal JUKESHUM: Jurnal Pengabdian Masyarakat Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Journal Healthy Purpose Journal of Pharmaceutical and Sciences. FASKES : Jurnal Farmasi, Kesehatan, dan Sains Jurnal Pengabdian Masyarakat Ilmu Kesehatan
Shufyani, Fahma
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Aktivitas antibateri sediaan hand and body lotion dari ekstrak etanol daun binahong (Anredera cordifolia (Ten.) Steenis) terhadap bakteri Staphylococcus aureus Dominica, Dwi; Anisah, Saskia; Wibowo, Risky Hadi; Shufyani, Fahma
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.405

Abstract

Background: Formulation is an activity to design the composition of the active ingredients and additional ingredients to make specific preparations. One of the herbal plants that can be formulated in hand and body lotion is binahong leaves (Anredera cordifolia (Ten.) Steenis), which contain secondary metabolites such as flavonoids, saponins, alkaloids, and tannins. These secondary metabolites function as antibacterials. Gram-positive bacteria often cause skin problems, such as Staphylococcus aureus. This study aimed to determine the antibacterial activity of 5%, 7.5%, 10%, 12.5%, and 15% binahong leaf extract hand and body lotion against S. aureus bacteria. This research was conducted experimentally, including an examination of the physical quality of the preparation (organoleptic, homogeneity, pH, spreadability, and adhesion). This Method research is an experimental study, including collecting samples, making kepok banana heart calyx juice with concentrations of 2%, 4% and 6%, ointment evaluation tests and cut wound healing activity tests on white mice which were grouped into five groups with each group consisting of of 5 mice. Statistical analysis included a one-way ANOVA test to see whether there was a significant difference between concentrations and wound healing in white male mice. The results showed that binahong leaf extract could be formulated into hand and body lotion preparations because it has a homogeneous composition, a pH range of 4.8-5.1, spreadability of 5.7-6.0 cm, and adhesion of 2.16-2.49 seconds. Hand and body lotion preparations with 10% binahong leaf extract have the best physical quality. All formulations of binahong leaf extract hand and body lotion in this study could inhibit the growth of S. aureus with weak inhibition, and the best formula for inhibiting the growth of S. aureus was 15% binahong leaf extract hand and body lotion having a diameter of inhibition zone 2.575 m.
Analisi manajemen pengetahuan terhadap kepatuhan minum obat pada pasien hipertensi di apotek Medan central care pharmacy Shufyani, Fahma; Siregar , Syati Manaharawan; Yulia , Rahma
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.572

Abstract

Introduction: Hypertension is one of the most dangerous health problems in the world, because hypertension is the main risk factor that leads to cardiovascular disease such as heart attack, heart failure, stroke and kidney disease. The aim of this study was to determine the relationship between level of knowledge and adherence to taking medication in hypertensive patients at the Medan Central Care Pharmacy.. This Method This research method uses quantitative descriptive analytical methods using a cross-sectional design. The sampling technique uses purposive sampling technique. Data were analyzed using the Chi Square test. Data collection was carried out in June 2023. The research population was hypertension sufferers at the Medan Central Care Pharmacy. The sample for this research was 97 respondent. The results of this study showed that the frequency distribution of high knowledge was 45 respondents (46.4%), medium was 36 respondents (37.1%) and low was 16 respondents (16.5%). The frequency distribution of medication adherence was 19 respondents (19.6%) high, 45 respondents (46.4%) medium and 33 respondents (34%) low. The results of the chi-square test of knowledge with medication adherence showed a p-value of 0.000<0.05. The conclusion in this study is that the respondent's level of knowledge about hypertension is in the high category, the respondent's level of medication adherence is in the medium category and there is a relationship between the level of knowledge and medication adherence in hypertension patients at the Medan Central Care Pharmacy.
Hubungan pengetahuan ibu dengan tindakan manajemen swamedikasi pada anak balita di Desa Ketapang Dua Aceh Timur. Shufyani, Fahma; Siregar, Syati Manaharawan; Dominica, Dwi
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.727

Abstract

Introduction: Self-medication is something that is often practiced by the Indonesian community as a way to take care of themselves when they are sick. Taking and consuming medication without advice from a healthcare professional, whether for diagnosis, prescription, or health supervision, is called self-medication. Self-medication can provide significant benefits to the government in maintaining national health if done correctly. Self-medication can assist healthcare professionals, reduce the time spent waiting for a doctor's diagnosis, and save money, especially in developing countries, because healthcare professionals will be more focused on more serious and critical health conditions. Objective: This study aims to determine mothers' knowledge about self-medication for fever and to understand the self-medication actions taken by mothers, as well as to examine the relationship between mothers' knowledge and their self-medication actions for fever in toddlers in Ketapang Dua Village, East Aceh. Method: This study uses a quantitative method of a descriptive-analytical nature with a cross-sectional design. The sampling technique used purposive sampling. Data were analyzed using the Chi Square test. Data collection was conducted in July 2024. The research population is the knowledge of mothers regarding self-medication management for toddlers in Ketapang Dua Village, East Aceh. The sample of this study consists of 40 respondents. Results: from this study indicate that 35% of mothers have a fairly good level of knowledge about self-medication for fever. Self-medication for fever in toddlers shows that around 47.5% have taken appropriate actions. There is a significant relationship between maternal knowledge and self-medication actions for fever in toddlers in Ketapang Dua Village, East Aceh, with a p-value of 0.026 < 0.05. It can be concluded that the presence of maternal knowledge regarding self-medication for fever in toddlers in Ketapang Dua Village, East Aceh, is classified as quite good. The conclusion: of this study is that the frequency distribution of maternal knowledge shows that some have fairly good knowledge, with 14 respondents (35.0%) and respondents with less adequate knowledge amounting to 21 respondents (65.5%). The frequency distribution of fever self-medication actions shows that some mothers provided appropriate self-medication actions, with 19 respondents (47.5%) doing so, while 21 respondents (52.5%) provided less appropriate self-medication actions. There is a significant relationship between maternal knowledge and self-medication practices for fever in toddlers in Ketapang Dua village, East Aceh, with a p-value of 0.026 > 0.05.
Formulasi salep sari batang daun talas (Colocasia esculenta L. ) schoot pada penyembuhan luka sayat pada tikus putih jantan (Rattus norvegicus) Ardiani, Rani; Shufyani, Fahma; Siregar, Syati Manaharawan; Silalahi , Ali Affan
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.730

Abstract

Introduction: Taro contains several compounds that can accelerate wound healing, such as flavonoids, phenols, and saponins. These compounds act as natural antibiotics, cleansing wounds with their antibacterial and antifungal properties. Therefore, this plant can aid in the wound healing process. Tannins, on the other hand, have the ability to constrict blood vessels and reduce bleeding in the wound area, decrease infection, and aid in wound healing during the inflammatory phase. One of the wound healing factors, vitamin C helps strengthen the walls of blood vessels, especially in the injured area, to maintain blood supply there and assist in accelerating collagen synthesis during the wound healing process. Lectin, a substance that can accelerate wound closure by aiding better cell regeneration. Arecaceae plants have many benefits for society, such as being used as a food source by harvesting their tubers, or being used as ornamental plants that beautify yards. Taro is also used as medicine both internally and externally. Almost all parts of the taro plant are processed into medicines, and the tubers, stem bark, and roots are crushed and then applied to the skin to heal wounds or bruises. Objective: This study aims to determine the wound healing effects of the sap from the taro stem (Colocasia esculenta L) Schott on male rats (Rattus norvegicus). Method: This study uses an experimental method, which includes sampling, preparation of taro leaf stem extract with concentrations of 2%, 4%, 6%, ointment evaluation test, and incision wound healing activity test on white rats grouped into 5 groups, each consisting of 3 rats. Statistical analysis includes one-way ANOVA to see if there is a significant difference between concentrations in the healing of incisional wounds in male white rats. Result: The research conducted shows that F1 (2% concentration) can heal the rats on the 10th day. F2 (4% concentration) the rats healed on the 8th day, F3 (6% concentration) the cut wounds healed on the 7th day, positive control (Betadine ointment) all rats healed on the 7th day. Conclusion: The extract of taro leaf stems (Colocasia esculenta L) Schoot can be formulated into an ointment preparation for the healing of incised wounds in male white rats (Rattus norvegicus), with the most effective concentration being 6% because it can heal incised wounds the fastest among the other concentrations.
Uji efektivitas ekstrak etanol daun bayam hijau (Amaranthus hybridus L.) sebagai imunostimulan pada mencit putih jantan (Mus musculus) Tarigan, Rida Evalina; Sinaga, Arinda Agnes; Shufyani, Fahma
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.735

Abstract

The immune system plays a critical role in defending the body against pathogens, and enhancing its activity through immunostimulants is essential for improving health. This study aims to evaluate the immunostimulatory potential of ethanol extract from green amaranth leaves (Amaranthus hybridus L.) in male white mice (Mus musculus). The ethanol extract green amaranth leaves was prepared from dried green amaranth leaves and tested for its effect on phagocytic activity using the carbon clearance method. Phytochemical screening revealed the presence of flavonoids, saponins, tannins, and steroids. The animals were divided into five groups: negative control (0.5% Na CMC), positive control (Stimuno Forte®), and three experimental groups receiving varying doses of the ethanol extract (125 mg/kg, 250 mg/kg, and 500 mg/kg body weight). The results indicated that the ethanol extract significantly enhanced phagocytic activity, with the most optimal effect observed at 125 mg/kg body weight. The stimulation index increased with higher doses, demonstrating the dose-dependent immunostimulatory effect. The study concludes that the ethanol extract of green amaranth leaves can serve as an effective natural immunostimulant, with the 125 mg/kg body weight dose being the most effective in enhancing immune function in male white mice. These findings suggest the potential of green amaranth as a therapeutic agent for immune-related disorders.
YOGHURT FORMULATION FROM RED DRAGON FRUIT AND ACTIVITY TEST AGAINST PATHOGENIC BACTERIA Permata Dewi, Asiska; Musdalifah, Dinda; Surya, Alfin; Shufyani, Fahma
Ensiklopedia of Journal Vol 8, No 1 (2025): Vol. 8 No. 1 Edisi 2 Oktober 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v8i1.3544

Abstract

The dairy product known as yogurt is fermented by lactic acid bacteria. The purpose of this study is to evaluate the properties and antibacterial activity of yogurt at concentrations of 0%, 10%, 20%, and 30% against harmful bacteria, specifically Escherichia coli and Bacillus subtilis. The properties were examined for lactic acid bacteria, viscosity, pH, hedonic value, and organoleptic features. The disk diffusion method was used to test the antibacterial activity. According to the findings of evaluating the yogurt's organoleptic properties, every formula was homogenous, thick, sour-tasting, and pink. The range of the viscosity values is 412 cP to 972 cP. The lactic acid bacteria vary from 6.8x10^9 to 9.0x10^9, and the pH levels fall between 4.26 and 4.42. In contrast, F3 was the most favored formula in the hedonic test. Following that, the average inhibition zones for the antibacterial activity of yogurt against E. coli bacteria at concentrations of 0%, 10%, 20%, and 30% were 7.5 mm, 9.9 mm, 11.2 mm, and 12.2 mm, respectively. In contrast, the inhibition zone diameters against B. subtilis bacteria were 7.4 mm, 9.8 mm, 13.1 mm, and 14.4 mm. A p-value of less than 0.05 indicated a statistically significant difference in antibacterial activity tests. Red dragon fruit yogurt shows antibacterial action against B. subtilis and E. coli, according to the diameter of the inhibition zone that was obtained.. Keywords: yoghurt, red dragon fruit peel, antibacterial activity, E. coli, B. Subtilis
Co-Authors Alfin Surya Anisah, Saskia Ardiani, Rani Asiska Permata Dewi Darmadi Darmadi Dominica, Dwi Fitri, Khairani Ginting, Ovalina Sylvia Br. Manaharawan Siregar, Syati Muhammad Andry Musdalifah, Dinda Naldi, Jefri Permata Dewi, Asiska Putriani, Kony Rahmah, Mawaddah Rida Evalina Tarigan Silalahi , Ali Affan Sinaga, Arinda Agnes Siregar , Syati Manaharawan Syati Manaharawan Siregar Wibowo, Risky Hadi Yulia , Rahma