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Journal : Medula

Hubungan Antara Hipertensi dan Usia dengan Angka Kejadian Kanker Payudara Di RSUD Dr. H. Abdul Moeloek Bandar Lampung Tahun 2018 Mohamad Reihansyah Deswindra; Muhartono; Rizki Hanriko; Waluyo Rudiyanto
Medula Vol 10 No 1 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i1.12

Abstract

Breast cancer is one of the most highest incidence rate cancer in all countries. Age and Hypertension is known as risk factor for breast cancer. The purpose of this study is to know the relation between hypertension and age with breast cancer incidence rates in Dr. H. Abdul Moeloek Bandar Lampung. The method of this study is observational analytic study with case control design. The data that used are secondary data that gathered from medical records of patients in Dr. H. Abdul Moeloek Hospital and taken with consecutive sampling method. The data is analyzed using univariate and bivariate analysis using Chi-square test and Fisher test. The result is in the case group, hypertension percentage obtained was 12.5% ​​while those whose has not hypertension was 87.5%. In the control group the percentage of hypertension was 8.3% while those whose has not hypertension was 91.7%. In the case group ≥50 years of age percentage obtained was 54.2% while at age <50 years was 45.8%. In the control group ≥50 years of age percentage of 16.7% while at age <50 years at 83.3%. The results showed that age ≥50 years have a p value = 0,007 with OR = 5,909 and hypertension group have a p value = 0.500. The conclusion of this study is, there is no the relationship between hypertension and breast cancer incidence rates Lampung and there is relationship between the age of patients with breast cancer incidence rates in the Hospital of Dr. H. Abdul Moeloek Bandar Lampung.
Pengaruh Pemberian Minuman Ringan Berkarbonasi terhadap Peningkatan Kadar Glukosa Darah dan Perubahan Diameter Pulau Langerhans Tikus Putih (Rattus norvegicus) Jantan Galur Sprague dawley Firinda Soniya; Waluyo Rudiyanto
Medula Vol 12 No 4 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i4.511

Abstract

The carbonated soft drinks consumption in this world have been increasing rapidly. Several of epidemiology studies have linked chronic consumption a carbonated soft drink with obesity, fatty liver disease, cardiovascular disease, metabolic syndrome, dental caries and osteoporosis. This research aims to determine the effect of carbonated soft drinks consumption to increase blood glucose levels and islets of Langerhans diameter changes rats in male Sprague dawley white rats (Rattus norvegicus). This research is a post test only control group design experimental study using 28 male white rats Sprague dawley which divided into 4 groups. K group only given an aquadest ad libitum 6 ml/200 gr/day, P1 group is given carbonated soft drinks 3 ml/200 gr/day, P2 group is given carbonated soft drinks 6 ml/200 gr/day and P3 group is given carbonated soft drinks 12 ml/200 gr/day for 30 days. The data of blood glucose levels was analysed by using One Way ANOVA test with result in p value=0.00 (p<0.05) then followed by Post Hoc LSD test with result in p value<0.05 for all of groups. The data of diameter Langerhans islets was analysed by using One Way ANOVA test with result in p value=0.394 (p>0.05). There is an effect of carbonated soft drinks consumption to increase blood glucose levels and there is no effect of carbonated soft drinks consumption to Langerhans islets diameter changes in Male Sprague dawley white rats (Rattus norvegicus) all 30 days long.
Anemia pada Pasien Tuberkulosis Inna Kurniaji; Waluyo Rudiyanto; Indri Windarti
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.592

Abstract

Tuberculosis (TB) is one of the most common causes of health problems in the world. The prevalence of TB in the world is estimated at 10.6 million, and 1.6 million of them died from TB, in Indonesia the incidence of TB reached 503,712. Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis, which is known to cause complex hematological disorders. The hematopoietic system is thought to be affected during TB infection, so that Hb levels tend to decrease along with bacterial increase, which eventually causes anemia. The article aims to determine the incidence of anemia in TB patients and the mechanism of anemia in TB patients. Based on the results of a literature review conducted on references found from 2012–2022, it shows that anemia is a common condition in TB. The mechanism that causes anemia in TB patients is due to its pathogenesis as a chronic inflammatory disease. Anemia is an indicator in providing clues to diagnosis, prognosis, complications and response to TB therapy. Nutritional intake and adherence to TB therapy need to be done properly to prevent the development of severe disease and improve the patient's quality of life.