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All Journal Medula Jurnal Medika Hutama JK Unila (Jurnal Kedokteran Universitas Lampung) Prosiding Konferensi Nasional PKM-CSR Majority Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Mukhlis Imanto
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Peningkatan Pengetahuan Siswa SMKN 2 Bandar Lampung Tentang Bahaya Rokok Melalui Penyuluhan Nisrina Aulia Amirah; Dyah Wulan Sumekar; Tri Umiana Soleha; Mukhlis Imanto
Medula Vol 10 No 2 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v10i2.65

Abstract

Smoking is a global health problem, almost every country experiences an increase in adolescent smokers. Indonesia is the third largest country with the highest number of smokers after China and India. Various methods have been used to reduce the number of smokers at an adolescent. One effective method of preventing an increase in the number of adolescent smokers is counseling about cigarette risk knowledge. In preliminary research, we got there are around 90% of smoking students especially male students. The cause is lack adolescent knowledge against the dangers of smoking. This research aims to know the effect of counseling on cigarette risk knowledge in student SMKN 2 Bandar Lampung. It was carried out in April 2017, place in SMKN 2 Bandar Lampung. The results of the hypothesis with the values of the t-test paired obtained p = 0000 that indicate a difference of knowledge comparison before and after counseling on Students of SMKN 2 Bandar Lampung. So it can be inferred that the counseling intervention can increase cigarette risk knowledge on students SMKN 2 Bandar Lampung.
Karsinoma Nasofaring dengan Multiple Cranial Nerve Palsy Pada Pasien Wanita Usia 52 Tahun Arilinia Pratiwi; Mukhlis Imanto
Medula Vol 9 No 4 (2020): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i4.223

Abstract

Nasopharyngeal Carcinoma is a malignant disease that appears in the nasopharyngeal area, namely the area above the throat and behind the nose. Nasopharyngeal carcinoma is an example of malignancy in the THT-KL and is the 4th most common malignancy case after breast cancer, cervical cancer, and lung cancer in Indonesia. The etiology of nasopharyngeal carcinoma is multifactorial, namely infection from Epstein Barr virus, genetic, and related to the environment such as consumption of salted fish, smoking habits, food preservatives, mosquito coils, and wood smoke. This case was found in a female patient, 52 years old, who came to Dr. Hospital. H. Abdoel Moeloek with complaints of headache since 2 months ago. Other complaints felt by patients are double vision, ringing in the ears, face feels numb on one side, pelo talk and tongue falling to one side, and nausea and weakness. There was a complaint of a lump appearing on the right neck since 5 months ago before complaints of headache appeared. The results of physical and supporting examinations and biopsy examinations have been carried out and the results obtained refer to the diagnosis of nasopharyngeal carcinoma. Treatment carried out on patients is symptomatic to reduce symptoms and is referred to a higher hospital for further treatment.
HUBUNGAN FAKTOR SOSIODEMOGRAFI TERHADAP STATUS GIZI ANAK SD NEGERI 1 PRINGSEWU SELATAN Isnida Shela Arlovi; Dyah Wulan Sumekar RW; Diana Mayasari; Mukhlis Imanto
Medula Vol 11 No 1 (2021): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v11i1.254

Abstract

Nutrition plays an important role in children health. The prevalence of underweight children in Indonesia by 11.2% to 4.0% was very thin and emaciated 7.2%, while the obese children by 18.8%, consisting of 10.8% obese children and obese amounted to 8.8%. Lampung Province was ranked second among the provinces with a skinny kid. The nutritional status itself can be affected by several things, one of which is the status of demographics. The purpose of this study is known association of sociodemographic factors with nutritional status of children. This type of research is an analytic observational with cross sectional approach. The population is students of SDN 1 South Pringsewu, with a sample size of 225 people. The statistical test used was chi - square. The results of the univariate analysis are mostly had normal nutritional status (68%), age 6-9 years (75.6%), female (51.1%), highly educated mothers (77.3%), father's occupation were self-employed (64%), parents have a high income levels (> Rp. 1.581 million) (69.3%). The results of the bivariate analysis obtained no relationship between maternal education level (p-value < 0.001), the type of father's occupation (p-value < 0.001), and the level of family income (p-value < 0.001) with the nutritional status of children. While there is no correlation between age (p-value = 0.829), and the child's gender (p-value = 0.307) with the nutritional status of children. Expected the school to coordinate with health officials in monitoring the nutritional status of their students. Keywords : Sociodemographic, nutritional status of children
Kolaborasi Tuberculosis (TBC) dan Human Immunodeficiency Virus (HIV) Yona Arisena Magdalena Silitonga; Intanri Kurniati; Retno Ariza; Mukhlis Imanto; Jhond Fatriyadi S
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.269

Abstract

Tuberculosis (TBC) is becoming one of the highest causes of death in the world. Tuberculosis is caused by Mycobacterium tuberculosis that is transmitted via droplet originating from tuberculosis patients. It is estimated that one-third of people in the world have been infected by tuberculosis, but only 10-20% of people will show the symptoms. Symptoms that can arise in tuberculosis are such as bleeding cough, weight loss, night sweats, chest pain, shortness of breath and weakness. Meanwhile, human immunodeficiency virus (HIV) is a retrovirus-famili because of its ability to convert the RNA genome into DNA. HIV transmission occurs due to the entry of this virus into the body through body fluids of people who are already infected by HIV. Both of these infectious diseases alike because both of them can cause a decrease in immune system activities in the body of the sufferer. Collaboration of both diseases is common and is a deadly combination because it interacts with each other in all aspects of the disease, ranging from pathogenesis, epidemiology, clinical manifestations, treatment and prevention. Tuberculosis is also a leading cause of death in HIV-positive patients. In 2016 in Indonesia, there are found 360,565 cases of TBC, with 14% of them are also known to suffer from HIV-positive. The results of the study suggest that there is a mutual relationship between the two diseases in causing a clinical symptoms through decreased activity of the body's immune system.
Faktor Risiko Kejadian Rinitis Alergi pada Anak Intan Nurhaliza Nurhaliza; Mukhlis Imanto
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.540

Abstract

Allergic rhinitis is one of the global health problems that affect about 400 million people in the world with prevalence of 8.38% in children and 14.93% in adolescents, in Indonesia the incidence of allergic rhinitis reaches 38%. Allergic rhinitis is a clinical symptom that occurs when the nasal mucous membrane is exposed to an allergen and induces an immune system-mediated inflammatory response. Allergic rhinitis can be triggered by several factors, including individual and environmental factors that can lead to resensitization and disease progression. The main risk factor for allergic rhinitis is family history of atopy, especially history of allergic rhinitis in both parents. The presence of atopic dermatitis, asthma, exposure to vehicle acids, cigarettes and house dust, obesity can be factors that increase the risk of allergic rhinitis in children. These risk factors have their respective mechanisms in increasing the risk of allergic rhinitis and have different levels of risk. Other factors such as gender and age did not contribute to increasing the risk of allergic rhinitis in children.
Hubungan Rinitis Alergi dengan Kejadian Asma Bronkial Dinni Istiqomah; Mukhlis Imanto
Medula Vol 13 No 1 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i1.611

Abstract

Allergic rhinitis is a risk factor for asthma.  The development of asthma is generally more common in patients with allergic rhinitis.  This is in accordance with epidemiological data which states that there has been an increase in cases of allergic rhinitis accompanied by asthma globally.  Allergic rhinitis and asthma are both mediated by Immunoglobulin E (IgE).  The correlation between nasal airflow obstruction in allergic rhinitis sufferers and lung airflow obstruction due to the inflammatory process that occurs in the nasal mucosa of allergic rhinitis and asthma sufferers can be determined by observing the nasal airflow and bronchial airflow.  The diagnosis of asthma can be known by measuring the Forced Expiratory Volume in One Second Percent (FEV1%) value.  In allergic rhinitis patients, a decrease in FEV1% was found and reversibility was found after a bronchodilator test.  Such reversibility is associated with long duration (chronic) allergic rhinitis and early bronchial airflow limitation.  This 1% decrease in FEV and reversibility suggest the presence of BHR, especially in persistent and moderate-severe allergic rhinitis patients.  Duration and type of sensitization (allergen) were identified as early prognostic markers of BHR involvement in allergic rhinitis patients.  Knowing the FEV1% value in allergic rhinitis sufferers is expected to be a preventive measure for the occurrence of asthma.
Case Report: Laki-Laki Usia 42 Tahun dengan Laryngopharingeal Refluks Farhan Ridho Pangestu; Mukhlis Imanto
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1759

Abstract

Laryngopharyngeal Reflux (LPR) is an inflammatory condition affecting the mucosa of the larynx and pharynx caused by the retrograde flow of gastroduodenal contents into the upper aerodigestive tract. This condition is frequently underdiagnosed due to its nonspecific symptoms, which often mimic other upper airway disorders. LPR presents with a wide range of clinical manifestations and is commonly managed by multiple medical disciplines without an accurate or standardized diagnostic approach. This case report aims to describe the clinical presentation, risk factors, diagnostic process, and management of LPR in an adult patient. We report the case of a 42-year-old male who presented with recurrent choking sensations, shortness of breath, dry cough, frequent throat clearing, and hoarseness persisting for four months, accompanied by worsening heartburn and epigastric discomfort. The patient had several predisposing factors, including obesity and unhealthy lifestyle habits such as high-fat and acidic food consumption and lying down shortly after meals. The diagnosis of LPR was established based on a Reflux Symptom Index (RSI) score of 14 obtained during anamnesis and a Reflux Finding Score (RFS) of 9 derived from indirect laryngoscopic examination. Management consisted of pharmacological therapy with high-dose proton pump inhibitors and antacids, combined with non-pharmacological interventions including lifestyle and dietary modifications. This integrated approach aims to reduce reflux episodes and mucosal inflammation. This case highlights the clinical importance of RSI and RFS as practical diagnostic tools for LPR and emphasizes the need for comprehensive management strategies to improve patient outcomes and quality of life.
Laporan Kasus : Pasien Perempuan 25 Tahun dengan Rhinitis Alergi Muchammad Aqsa Enrico Ricardo; Mukhlis Imanto
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1792

Abstract

Allergic rhinitis is an immunoglobulin E mediated inflammation of the nasal mucosa characterized by recurrent sneezing, nasal obstruction, rhinorrhea, and ocular symptoms such as itching and tearing. This condition is commonly observed in young adults and is closely associated with environmental allergen exposure and genetic predisposition. This case report describes a 25 year old woman who presented with recurrent nasal obstruction for the past four years. The symptoms were more pronounced in the morning and during exposure to cold air. The patient also reported repetitive sneezing episodes, occurring 10 to 15 times after exposure to dust, accompanied by clear rhinorrhea, nasal and ocular itching, and a habitual nose rubbing behavior. Ocular complaints, including watery and itchy eyes, were consistently reported. Physical examination revealed livid discoloration of the nasal cavity mucosa and septum. The inferior turbinates appeared edematous and hyperemic with clear nasal secretions. No septal deviation or signs of acute infection were observed. Based on the persistence of symptoms for more than four weeks and the characteristic clinical findings, the patient was diagnosed with mild persistent allergic rhinitis. Management included oral antihistamine therapy with cetirizine, a nasal decongestant containing pseudoephedrine hydrochloride, and intranasal corticosteroid therapy with fluticasone furoate. In addition to pharmacological treatment, the patient received education on allergen avoidance, adoption of healthy lifestyle practices, and regular physical activity. This case highlights the importance of recognizing long term symptoms, performing a thorough physical examination, and applying an appropriate combination of pharmacological and non pharmacological interventions to achieve symptom control, improve quality of life, and prevent disease progression in patients with allergic rhinitis.
Tonsilitis Akut pada Anak : Laporan Kasus Aisyah Lubis; Mukhlis Imanto
Medula Vol 17 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v17i1.1970

Abstract

Acute tonsillitis is a common ENT disease in children, characterized by sudden inflammation of the tonsils due to viral or bacterial infections. This condition can cause impaired swallowing, breathing, sleep, and reduce children's quality of life if not properly treated. We report a case of a 9-year-old boy with painful swallowing for 5 days, accompanied by fever, cough, runny nose, and snoring. Physical examination revealed T3-T3 tonsillar enlargement, bilateral hyperemia (+/+), no detritus, and no lymphadenopathy. The patient's Centor score was 1, leading to a diagnosis of acute tonsillitis of viral etiology. The patient received symptomatic therapy (paracetamol, rest, hydration, warm salt water gargling, and education) without antibiotics.
Otitis Media Supuratif Kronik Auris Dextra Tipe Aman Fase Aktif Pada Anak Usia 2 Tahun : Sebuah Laporan Kasus Indah Kurnia Putri Waruwu; Mukhlis Imanto
Medula Vol 16 No 4 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i4.1971

Abstract

Benign-type chronic suppurative otitis media (CSOM) is a chronic middle ear infection characterized by a central tympanic membrane perforation and persistent otorrhea without cholesteatoma, with inflammation limited to the middle ear mucosa. Benign-type CSOM cases in children under 3 years of age are rarely reported, despite this age group having a high risk of recurrent ear infections due to the immature anatomy of the Eustachian tube, which is shorter, wider, and more horizontal compared to that of adults. We report a case of a 2-year-old boy who presented to the ENT Outpatient Clinic of Dr. H. Abdul Moeloek Regional General Hospital, Lampung Province, with a 2-month history of yellowish-white discharge from the right ear. The complaint was accompanied by hearing loss, indicated by the child not turning his head when called from behind. History-taking revealed six episodes of recurrent upper respiratory tract infection (URTI) within the past year, as well as exposure to cigarette smoke from the patient's father at home. Both conditions were significant risk factors contributing to the development of CSOM. Otoendoscopic examination revealed a subtotal central perforation of the pars tensa of the right tympanic membrane without cholesteatoma, establishing the diagnosis of active benign-type CSOM. The patient received aural toilet with 3% hydrogen peroxide for 3–5 days to clear the discharge, followed by topical ofloxacin 0.3% for 14 days. Parental education was provided regarding proper medication administration, keeping the ear dry, and avoiding cigarette smoke exposure. Accurate diagnosis and appropriate management are essential to prevent hearing impairment and delayed speech and language development in children.
Co-Authors Aironi Irsyahma Aisyah Lubis Anggraeni Janar Wulan Ari Wahyuni Arilinia Pratiwi Diana Mayasari Dinni Istiqomah Dyah Wulan Sumekar Dyah Wulan Sumekar RW Ety Apriliana Farhan Ridho Pangestu Helmi Ismunandar Indah Kurnia Putri Waruwu Intan Fajar Ningtyas Intan Nurhaliza Nurhaliza Intanri Kurniati Isnida Shela Arlovi Jhons Fatriyadi Suwandi M. Farhan Rozak Mai Rista Nila Sari Muchammad Aqsa Enrico Ricardo Muhammad Yusran Muhartono Muhartono Nabila Rayhan Yasmin Nadia Rosmalia Dewi Nisrina Aulia Amirah Rani Himayani Rasmi Zakiah Oktarlina Reni Zuraida Retno Ariza Rizky Hanriko Rr Astri Nur Azizah Utama Salsabila Dwi Irga Syarif Septia Eva Lusiana TA Larasati Tondi Rosalinda Mandalahi Tri Umiana Soleha Tri Umiana Soleha Wildan Kautsar Irawan Wulan Noventi Yona Arisena Magdalena Silitonga