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All Journal Indonesian Journal of Pharmaceutical Science and Technology JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan Journal SAGO Gizi dan Kesehatan Narra J Proceedings of International Conference on Multidiciplinary Research JURNAL KESEHATAN SAMODRA ILMU Pharmaceutical Sciences and Research (PSR) Jurnal Kedokteran Hewan JURNAL ILMU KESEHATAN MULIA MADANI YOGYAKARTA DIMASLIA Jurnal Bidan Srikandi
Husna, Fauzul
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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The Effectiveness of Feeding Azolla Microphylla on Catfish (Clarias Batrachus) Growth Noviyanti, Anita; Husna, Fauzul; Ridhwan, Muhammad; Surya, Erdi; Armi, Armi; Masyudi, Masyudi; Walil, Kamalliansyah
International Conference on Multidisciplinary Research Vol 3, No 1 (2020): ICMR
Publisher : Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (312.483 KB) | DOI: 10.32672/pic-mr.v3i1.2601

Abstract

The usage of Azolla Microphylla as fish feed provides several advantages for fish farmers such as; the low-cost, the easy-to-obtain, and the taste that is favoured by some freshwaterfish especially catfish (Clarias Batrachus). Azolla Microphylla is known as one ofPterideophyte aquatic plants that can be utilized as fish feed for catfish because of its highnutritional values, including N, P, Si, Ca, Fe, Mg, and some others. This study aims to analyzethe effectiveness of feeding Azolla Microphylla on catfish length and weight growth by anexperimental method. A completely randomized design was conducted with 5 treatments and 4repeatabilities using 20 fish farms containing a cluster of catfish with an average size of 5 cm,that regularly fed with Azolla Microphylla. The observation was conducted every 10 daysduring the treatment, with a total number of observations held 4 times in the 40-daystreatment. The result indicated that the treatment in P2, with a 60-gram dosage of AzollaMicrophylla feeding, gives the optimal growth on catfish length and weight compared to othertreatments. Best scores in P2 treatment is found in the fourth observation, where the catfishlength reaches around 28 cm, and the weight reached 100 gram. Based on the single factorANOVA test, the real difference values for each group and treatment which analysed at asignificance level of 0,05, namely FvaluesFtable, indicates a significant effect of AzollaMicrophylla on the catfish growth. The Tukey’s Honest Significant Difference test also showsa significant effect of the Azolla Microphylla feeding on the catfish length and weight growth.Therefore, feeding catfish with 60-gram of Azolla Microphylla creates an effective treatmentto gain catfish length and weight.Keywords: Azolla Microphylla, Feeding, Fish Feed, Catfish Growth 
Model Hewan Coba pada Penelitian Diabetes Husna, Fauzul; Suyatna, Franciscus D; Arozal, Wawaimuli; Purwaningsih, Erni H
Pharmaceutical Sciences and Research Vol. 6, No. 3
Publisher : UI Scholars Hub

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Abstract

The animal model has been widely used and contributed vastly to the scientific research over the years. While it can be used as an alternate subject in a study, the selection of the animal is crucial to assess and investigate the influence of the environment and genes on the pathogenesis of a disease. Many factors contribute to the choosing of the animal. They can be ranged from the similarities with the modelled object, easily looked after with less expensive cost, good reproductive performance, ability to produce blood and tissue samples, well-known genetic composition, and the status of the disease can be explained. Research has been taking place to investigate and find the best approach to prevent and deal with diabetes mellitus (DM) and insulin resistance and its complications. It starts with an initial in vitro method and finished with a clinical trial. Similarly, a series of in vivo studies using the animal model has been done aiming at figuring out its conditions or diseases that are identical to that of humans. This article discusses a variety of animal models frequently used in DM research.
Antioxidant and antiaging activity of Cinnamomum burmannii and Michelia champaca extract and combinations Qarani, Waisul; Husna, Fauzul; Yulia, Winda; Zulkarnain, Zulkarnain; Syahrizal, Dedy; Gani, Basri A.; Sary, Nirwana L.; Wardhani, Bantari WK.
Narra J Vol. 3 No. 2 (2023): August 2023
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v3i2.111

Abstract

Aging is a natural skin process that occurs due to intrinsic and extrinsic factors, such as excessive exposure to ultraviolet light (photoaging). The mechanism of damage involves the production of excess free radicals that trigger oxidative stress in the skin. Determining the natural products that have high antioxidant activities as antiaging is up most important. Cinnamomum burmannii and Michelia champaca are typical Aceh plants that are believed to have high antioxidant effects. The aim of this study was to determining the contents of C. burmannii and M. champaca as well as to determine the antioxidant and antiaging activities of either individually or combinations. The qualitative phytochemical and semi-quantitative analysis of the extracts were conducted using gas chromatography and mass spectroscopy (GC-MS). The antioxidant activity was examined by radical scavenging using the DPPH radical while the antiaging activity was tested the tyrosinase enzyme inhibition test. The phenolic and flavonoid contents of C. burmannii were higher than M. champaca (66.34 vs 24.71 mg gallic acid equivalent/gr) and (80.52 vs 60.20 mg quercetin equivalent/gr). The inhibitory concentration (IC₅₀) of M. champaca extract in inhibiting DPPH indicated that M. champaca had a better antioxidant activity than C. burmannii. The combination of C. burmannii and M. champaca extracts had a lower IC₅₀ compared to M. champaca alone. C. burmannii and M. champaca extract had a weak potential to inhibit tyrosinase activity (IC₅₀ value ≥1000 µg/mL). In conclusion, this study indicates that M. champaca and C. burmannii have strong antioxidant activities and these might associate with polyphenol contents.
Wound healing effect of nutmeg (Myristica fragrans) cream on second-degree burn in animal model Angilia, Ciecielia; Sary, Nirwana L.; Indah, Rosaria; Suryawati, Suryawati; Farsa, Bianda S.; Zeir, Haya A.; Fajri, Fauzan; Husna, Fauzul
Narra J Vol. 4 No. 1 (2024): April 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i1.621

Abstract

Second-degree burn, the most common among burn degrees, underscores the importance of timely and proper treatment in influencing prognosis. Nutmeg (Myristica fragrans), renowned for its potent antibacterial and antifungal properties, also serves as an effective antiseptic for open wounds. The aim of this study was to identify the phytochemical constituents of nutmeg essential oil and analyze the wound healing effect of nutmeg cream on second-degree burns in an animal model. An experimental study with a completed randomized design was conducted on Rattus norvegicus strain Wistar rats with second-degree burn. This study had four groups and each group consisting of four rats: B (burn-treated base cream), B+N (burn-treated 3% nutmeg cream), B+SSD (burn-treated silver sulfadiazine (BSS)), and B+N+SSD (burn-treated 3% nutmeg cream and SSD in a 1:1 ratio). The phytochemical analysis of nutmeg essential oil was conducted by gas chromatography and mass spectroscopy (GC-MS). The burn diameter and burn wound healing percentage were measured from day 0 to 18. One-way ANOVA followed by post hoc analysis using the least significant difference (LSD) was employed to analysis the effect. The phytochemical analysis of nutmeg essential oil found that myristicin, terpinene-4-ol, terpinene, safrole and terpinolene were the most abundant putative compounds in nutmeg essential oil. On day 0, the average burn wound diameters were 1.4 cm in all groups and increases were observed in all groups in day 3. The wound diameter decreased until day 18 with the smallest burn wound diameter was found in the B+N group (0.86±0.37 cm), followed by B+SSD (0.93±0.29 cm). The B+SSD group exhibited the highest percentage of burn wound healing (56.80±14.05%), which was significantly different from the base cream (p<0.05). The percentage of burn wound healing in rats given 3% nutmeg cream was 41.88±13.81% suggesting that nutmeg cream could promote burn wound healing in rats induced by second-degree burns.
TINGKAT KECEMASAN LANSIA BERDASARKAN DEPRESSION ANXIETY STRESS SCALE 42 (DASS 42) DI POSYANDU LANSIA MEKAR RAHARJA DUSUN LEMAH DADI BANGUNJIWO, KASIHAN BANTUL Husna, Fauzul; Ariningtyas, Nurul
Jurnal Kesehatan Samodra Ilmu (JKSI) Vol 10 No 1 (2019): JURNAL KESEHATAN SAMODRA ILMU (JKSI)
Publisher : LPPM Sekolah Tinggi Ilmu Kesehatan Yogyakarta

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Abstract

Latar Belakang: Masalah kependudukan merupakan masalah yang dihadapi oleh semua negara maju dan berkembang termasuk Indonesia Laporan Staistik Center RI (2016), di Indonesia sendiri memiliki lansia sebanyak 13.729,992 juta orang lanjut usia. Meningkatnya jumlah lansia di Indonesia akan menimbulkan masalah kompleks baik dari masalah fisik maupun psikososial. Masalah psikososial yang paling umum pada orang tua adalah kecemasan. Tujuan penelitian ini adalaah untuk mengetahui gambaran kecemasan lansia di Pos Pelayanan Terpadu Lansia Mekar Raharja, Lemah Dadi, Bangunjiwo, Kasihan, Bantul, Yogyakarta. Metode Penelitian: Penelitian ini menggunakan metode deskriptif. Populasi penelitian ini adalah lansia yang aktif di Pos Pelayanan Terpadu Lansia Mekar Raharja, Lemah Dadi, Bangunjiwo, Kasihan, Bantul, Yogyakarta. Total populasi dalam penelitian ini adalah 61 lansia. Metode sampel adalah accidental sampling. Analisis menggunakan analisis univariat. Hasil penelitian: Jumlah lansia dengan tingkat kecemasan lansia normal 67,3%, tingkat kecemasan lansia lebih ringan 20,0%, tingkat kecemasan lansia 9,1%, tingkat kecemasan berat lansia 3,6%, tingkat kecemasan lansia berat sekali 0%. Kesimpulan: Deskripsi kecemasan lansia di Pos Pelayanan Terpadu Lansia Mekar Raharja, Lemah Dadi, Bangunjiwo, Kasihan, Bantul, Yogyakarta dalam kategori tingkat normal.
Nilai nutrisi ekstrak buah nipah dan pengaruhnya terhadap glucose transporter-2 (GLUT-2) pada tikus yang diinduksi STZ Fitri, Yulia; Wagustina, Silvia; Husna, Fauzul; Suryana, Suryana; Zakiah, Noni; Sastri, Sastri
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 2 (2024): April
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i2.1669

Abstract

Background: The nutritional content of nipah fruit such as zinc and fiber plays an important role in regulating blood sugar levels in diabetes patients (DM). One way to increase the concentration of nutritional value and bioactive substances in palm fruit is to extract it. Active compounds such as tannins, flavonoids, polysaccharides, saponins, and terpenoids in palm fruit extract can inhibit the activity of amylase and glucosidase enzymes, which are mediated by Glucose Transporter-2 (GLUT-2) so that they affect controlling blood sugar levels. GLUT-2 is a protein that plays a role in transporting glucose from outside to inside cells, so it plays an essential role in maintaining balanced blood sugar levels.Objective: This research aims to examine the nutrients in palm fruit extract and its effect on Glucose transporter-2 (GLUT-2) in STZ-induced  in rats.Method: This study is experimental research using experimental laboratory methods carried out in the FKH USK laboratory in June 2022. Making nipah fruit extract is carried out by maceration using 95% ethanol. Carbohydrate, protein, fat, zinc, and Fe levels were analyzed using the Luff Schoorl, Kjeldahl, Soxhletasi, and AAS test method. Testing for water content and crude fibre uses a gravimetric test. Twenty-five rat samples were divided into four groups and induced with STZ 40 mg/kg BW. Checking blood sugar levels is needed to see hyperglycemic conditions in rats. GLUT-2 measurement after administering nipah extract for one month using the ELISA technique. The data obtained were analyzed by an ANOVA test.Results: Based on the results, it was found that fruit extract contained 15,79% carbohydrates, 7,04% protein, 6,02% fat, 0,0327% zinc, water content 24,05% and crude fibre 0,36%. The average GLUT-2 level in the control group was 7,24 ± 1,35 ng/ml, the DM group was 6,75 ± 0,81 ng/ml, the DM+extract group was 6,84 ± 0,56 ng/ml, the DM+metformin group was 7,34 ± 0,86ng/ml, and the DM+extract+metformin group was 6,93± 1,01 ng/ml.Conclusion: Nipah fruit extract contains carbohydrates, protein, fat and zinc. Administration of palm fruit extract for one month did not significantly effect on GLUT-2 in various groups of rats (0,83).  
GAMBARAN PERILAKU TENTANG KEBERSIHAN GENETALIA SAAT MENSTRUASI PADA REMAJA PUTRI MASJID JOGOKARIYAN YOGYAKARTA Husna, Fauzul; Aringtyas, Nurul
Jurnal Ilmu Kesehatan Mulia Madani Yogyakarta Vol. 5 No. 1 (2024): JIK MMY : JURNAL ILMU KESEHATAN MULIA MADANI YOGYAKARTA
Publisher : Akademi Kebidanan Mulia Madani Yogyakarta

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Abstract

Latar Belakang : Siklus menstruasi merupakan bagian awal dari kesehatan reproduksi remaja putri. Masalah umum terkait kesehatan reproduksi remaja adalah tidak dapat menerapkan cara perawatan bagian reproduksi (hygiene alat reproduksi), terutama pada saat menstruasi. Saat haid, pembuluh darah di rahim terbuka sehingga sangat rentan terhadap infeks infeksi saluran reproduksi lebih banyak terjadi pada seseorang yang tidak menjaga hygiene saat menstruasi. Tujuan Penelitian : Mengetahui gambaran perilaku tentang kebersihan genetalia saat menstruasi pada Remaja Masjid Jogokariyan (RMJ) Yogyakarta Metode Penelitian : Menggunakan jenis penelitian deskriptif kuantitatif. Populasi dalam penelitian ini yaitu remaja putri sebanyak 35 responden. Sampel diambil dengan teknik purposive sampling. Instrumen penelitian menggunakan kuesioner yang terdiri dari 28 pertanyaan. Analisa data menggunakan analisis univariant. Hasil Penelitian : Diketahui karakteristik remaja putri berdasarkan umur yaitu mayoritas berusia 20 tahun sebanyak 7 responden (21,2%), karakteristik remaja putri berdasarkan sumber informasi yaitu sebagian besar responden mendapatkan sumber informasi dari media massa sebanyak 20 responden (60,6%), karakteristik remaja putri berdasarkan perilaku yaitu tingkat perilaku remaja putri di Masjid Jogokariyan Yogyakarta yakni kategori Baik sebanyak 21 responden (63,6%). Kesimpulan : Karakteristik remaja putri berdasarkan umur (21,2%), karakteristik remaja putri berdasarkan sumber informasi dari media massa yaitu (60,6%), karakteristik remaja putri berdasarkan tingkat perilaku yaitu (63,6%). Kata Kunci : tingkat perilaku, remaja putri, personal hygiene
Antioxidant Potential, Anti-Diabetes, and Toxicity of Aceh Cinnamon Extract (Cinnamomum burmannii) Husna, Fauzul; Suhaila, Suhaila; Syahrizal, Dedy; Zulkarnain, Zulkarnain; Washilah, Hasya; Sahriana, Ananda Putri
Indonesian Journal of Pharmaceutical Science and Technology Vol 11, No 1 (2024)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v11i1.43182

Abstract

Indonesia as a mega biodiversity country must take a role in the development of herbal-based medicine. Cinnamon is often used empirically to overcome various health problems, especially diabetes.   This study aims to assess the effectiveness of Aceh cinnamon extract as an antioxidant and antidiabetic in vitro and to evaluate the toxicity of the extract. Cinnamons, obtained from coffee plantations in Simpang Teritit, Bener Meriah, Aceh, were macerated with 96% ethanol for extraction.  Furthermore, the extract phytochemical content was determined qualitatively, semiquantitatively (GC-MS), and quantitatively (levels of phenols, flavonoids, and total tannins).  The toxicity level was measured by an acute toxicity test based on the OECD and the BSLT assay.  The effectiveness as an antioxidant and anti-diabetes was determined in vitro by the DPPH inhibition method and α-glucosidase inhibition. The results of this study showed that cinnamon extract contains alkaloids, flavonoids, polyphenols, tannins, quinones, saponins, and triterpenoid compounds. The total amount of phenol, flavonoid, and tannin extract levels were 66.34 mg GAE/gr, 80.52 mg QE/gr, and 566.33 mg AT/gr. The IC50 extract value against DPPH was 16.07 ppm and against the enzyme, α-glucosidase was 123.52 ppm. In the acute toxicity test, the value of LD50 ≥15 grkg BWW was obtained and in the toxicity test with BSLT, LC50 extract was 350.57 ppm. Aceh cinnamon extract (Cinnamomum burmannii) has LD50 > 15 gr/kg BW and LC50 value >500 ppp which is categorized as a practically non-toxic ingredient and low toxicity agent with strong antioxidant activity and moderate antidiabetics.
PENGARUH PENYULUHAN TERHADAP PENINGKATAN PENGETAHUAN IBU TENTANG PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) PADA BALITA Andani, Mahardika Ratih Resti; Puspitasari, Riadinata Shinta; Latifahanun, Este; Husna, Fauzul
Jurnal Pengabdian Kepada Masyarakat Mulia Madani Yogyakarta Vol. 2 No. 2 (2024): DIMASLIA JURNAL PENGABDIAN MASYARAKAT UNIVERSITAS ISLAM MULIA
Publisher : Jurnal Pengabdian Kepada Masyarakat Mulia Madani Yogyakarta

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Abstract

Latar Belakang: Diharapkan masyarakat memiliki kemampuan untuk berpartisipasi dalam pembangunan kesehatan dengan menjaga, memelihara, dan meningkatkan kualitas kesehatan mereka. Perilaku Hidup Bersih dan Sehat (PHBS) keluarga adalah salah satu faktor yang menentukan kesehatan keluarga. Data Riskesdas 2018 menunjukkan bahwa jumlah rumah tangga yang ber-PHBS di Indonesia meningkat sebesar 70,62% dari tahun 2017. Namun, data dari Dinas Kesehatan Kabupaten Kulon Progo menunjukkan bahwa capaian rumah tangga yang ber-PHBS pada tahun 2021 rendah, sekitar 21,71%. Tujuan: Kegiatan pengabdian kepada masyarakat bertujuan untuk meningkatkan pengetahuan Ibu tentang PHBS dalam rumah tangga melalui penyuluhan. Metode: Kegiatan pengabdian masyarakat ini dilakukan untuk mendorong perilaku hidup bersih dan sehat sehingga keluarga lebih menyadari PHBS. 30 Ibu berpartisipasi dalam kegiatan ini di Posyandu Belik Kalurahan Demangrejo, yang berlangsung pada tanggal 11 Januari 2024. Hasil: Hasil dari kegiatan pengabdian menunjukkan bahwa pengetahuan Ibu tentang perilaku hidup bersih dan sehat (PHBS) sebelum dan setelah penyuluhan berpengaruh. Ini adalah indikator keberhasilan kegiatan. Setelah penyuluhan, pengetahuan ibu balita meningkat dari hanya 15 orang (50%) sebelum penyuluhan menjadi 25 orang (83,3%). Kata kunci : Pengetahuan, Perilaku , Penyuluhan
KONSELING INFORMASI EDUKASI (KIE) TENTANG KEHAMILAN, PERSALINAN DAN NIFAS PADA PASANGAN USIA SUBUR DI DUSUN DADABHONG, SENDANG SARI, KAPANEWON PAJANGAN BANTUL Pratiwi, Fika; Husna, Fauzul; Puspitasari, Riadinata Shinta
Jurnal Pengabdian Kepada Masyarakat Mulia Madani Yogyakarta Vol. 2 No. 2 (2024): DIMASLIA JURNAL PENGABDIAN MASYARAKAT UNIVERSITAS ISLAM MULIA
Publisher : Jurnal Pengabdian Kepada Masyarakat Mulia Madani Yogyakarta

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Abstract

Pasangan Usia Subur adalah Pasangan suami istri yang saat ini hidup bersama, baik bertempat tinggal resmi ataupun tidak, dimana usia istri antara20 tahun sampai 45 tahun. Pasangan usia subur batasan usia yang digunakan disini adalah 20-45 tahun. Pasangan Usia Subur berkisar antara usia 20-45 tahun dimana pasangan (laki-laki dan perempuan) sudah cukup matang dalamsegala hal terlebih organ reproduksinya sudah berfungsi dengan baik. Ibu hamil adalah seorang wanita yaedang mengandung yang dimulai dari konsepsi sampai lahirnya janin. Kehamilan adalah waktu transisi, yaitumasaantara kehidupan sebelum memiliki anak yang sekarang berada dalamkandungan dan kehidupan nanti setelah anak itu lahir (Ratnawati, 2020) Kehamilan merupakan penyatuan dari spermatozoa dan ovumdan dilanjutkandengan nidasi. Bila dihitung dari saat fertilisasi hingga lahirnya bayi, kehamilan normal akan berlangsung dalam waktu 40 minggu atau 9 bulanmenurut kalender internasional. Maka, dapat disimpulkan bahwa kehamilanmerupakan bertemunya sel telur dan sperma di dalam atau diluar Rahimdanberakhir dengan keluarnya bayi dan plasenta melalui jalan lahir (Yulaikhah,2019)
Co-Authors AA Sudharmawan, AA Alodia, Helen Andani, Mahardika Ratih Resti Angilia, Ciecielia Aqila, Fitri Aringtyas, Nurul Armi, Armi Basri A. Gani, Basri A. Dedy Syahrizal Dyah, Isna Puri Erni H Purwaningsih, Erni H Fajri, Fauzan Farsa, Bianda S. Fika Pratiwi, Fika Hasan, Denny Irmawati Latifahanun, Este Maesaroh, Putri Masyudi Masyudi Miswari, Irna Noni Zakiah Noviyanti, Anita Nurul Ariningtyas, Nurul Pratiwi, Cika Putri Puspitasari, Riadinata Shinta Qarani, Waisul Rosaria Indah Sahriana, Ananda Putri Sary, Nirwana L. Sastri Sastri Shinta, Riadinata Silvia Wagustina, Silvia Suhaila, Suhaila Surya, Erdi Suryana Suryana Suryawati Suryawati Suyatna, Franciscus D Syahputra, Andika Ari Vita Amelia, Vita Walil, Kamalliansyah Wardhani, Bantari WK. Washilah, Hasya Wawaimuli Arozal Winda Yulia Winda, Agestya Yulia Fitri Zeir, Haya A. Zubaidah, Irul Zulkarnain Zulkarnain