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All Journal HAYATI Journal of Biosciences Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Jurnal Wiyata : Penelitian Sains dan Kesehatan As-syifaa Jurnal Farmasi Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Meditory : The Journal of Medical Laboratory Jurnal Sintesis: Penelitian Sains, Terapan dan Analisisnya Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Sari, Fita
Department Of Pharmaceutical And Food Analysis, Faculty Of Pharmacy, Institut Ilmu Kesehatan Bhakti Wiyata Kediri, Kediri, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN BELUNTAS (Pluchea indica L.) ETANOL 70% DAN ETIL ASETAT MENGGUNAKAN DPPH Asih Imulda Hari Purwani; Fita Sari; Muhammad Dhika Ramadhan; Herlinda Mawardika
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.740

Abstract

Pluchea indica L. is a herbaceous plant of the Asteraceae family that has been known to the public as fresh vegetables and traditional medicine since ancient times. This study aims to determine the antioxidant activity of beluntas leaves obtained from the extraction using 70% ethanol and ethyl acetate. The identification of phytochemical screening of beluntas leaves revealed the presence of flavonoids, tanninsand alkaloids. The test of antioxidant activity was performed using the DPPH method as free radical and vitamin C as a comparison. The average IC50 value beluntas leaves in 70% ethanol solvent is 94.06 ppm, in ethyl acetate is
Kandungan Fenolik Dan Flavonoid Total Pada Ekstrak Daun Srikaya (Annona squamosa L.) Terfermentasi dyah aryantini; Fita Sari; Citra Rahma Wijayanti
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol. 7 No. 2 (2020)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/farmasains.v7i2.5635

Abstract

Daun srikaya mengandung senyawa fenolik dan flavonoid yang dapat digunakan sebagai antioksidan, antidiabetik, hepatoprotektif, antitumor. Fermentasi menyebabkan perubahan senyawa kimia sehingga mempengaruhi bioaktivitas tanaman. Tujuan dari penelitian ini adalah untuk mengetahui kandungan total fenolik dan flavonoid pada ekstrak daun srikaya dan ekstrak daun srikaya terfermentasi probiotik dengan lama fermentasi 24, 48 dan 72 jam. Ekstraksi daun srikaya dengan metode maserasi menggunakan pelarut etanol 70%. Penetapan kandungan total fenolik dan flavonoid menggunakan spektrofotometri UV-Vis. Kandungan total fenolik ditetapkan dengan asam galat konsentrasi baku seri 40, 55, 70, 85, 100 ppm, penentuan kandungan total flavonoid dengan kuersetin konsentrasi 40, 65, 90, 115, 140 ppm. Hasil penetapan kandungan total fenolik ekstrak adalah 4,028±0,064 mgGAE/g, sedangkan kandungannya pada ekstrak terfermentasi berturut-turut pada 24, 48, 72 jam yaitu 8,817±0,079; 7,391±0,018 dan 5,997±0,078 mgGAE/g. Kandungan total flavonoid ekstrak 3,861±0,041 mgQE/g, pada ekstrak terfermentasi jam ke-24, 48, 72 berturut-turut yaitu 17,022±0,392; 11,691±0,268 dan 9,227±0,243 mgQE/g. Kesimpulan yang diperoleh adalah proses dan lama fermentasi mempengaruhi kandungan total fenolik dan flavonoid pada ekstrak daun srikaya dan ekstrak daun srikaya terfermentasi.
ANALYSIS OF PLATELET-LYMPHOCYTE RATIO IN TYPE 2 DIABETES MELLITUS AS A SYSTEMIC INFLAMMATION BIOMARKER Fathul Hidayatul Hasanah; Sri Wahyuni; Danny Meganingdyah Primartati; Aulia Risqi Fatmariza; Fita Sari
Meditory : The Journal of Medical Laboratory Vol. 14 No. 1 (2026): Meditory, Volume 14 No. 1 Tahun 2026
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v14i1.4056

Abstract

Background: Chronic hyperglycemia in type 2 DM causes chronic low-grade systemic inflammation, which triggers complications. The body responds with an increase in proinflammatory cytokines and changes in blood cell hemostasis. The platelet lymphocyte ratio (PLR) is a new inflammatory marker that has clinical prognostic value. Objective: Comparison of PLR values in type 2 DM without complications with the cardiovascular and nephropathy complication groups. Methods: The study employed a retrospective research design and included a total of 617 respondents with type 2 DM. The respondents were divided into three groups: 162 with uncomplicated type 2 DM, 291 with cardiovascular complications, and 164 with nephropathy. The data was collected from Mojowarno Christian General Hospital in Jombang. Results: The mean value of PLR in uncomplicated type 2 DM was 238.4 ± 225, in cardiovascular 327.11 ± 162, and in nephropathy 449.52 ± 107. The difference test yielded a statistically significant result p < 0.001, indicating that there were notable differences in PLR values across the three type 2 DM groups. Conclusions: There is a difference in PLR values in type 2 DM between the group without complications and the group with complications (cardiovascular and nephropathy).
Co-Authors Angelia Sukmana Asih Imulda Hari Purwani Atmira Sariwati Aulia Risqi Fatmariza Citra Rahma Wijayanti Danny Meganingdyah Primartati Desi Suci Handayani Dyah Aryantini, Dyah Farida Noor fathul hasanah Fathul Hidayatul Fathul Hidayatul Hasanah Fathul Hidayatul Hasanah, Fathul Hidayatul Hamdan Dwi Risqi Herlinda Mawardika Ida Kristianingsih Lailiyah, Munifatul Muhammad Dhika Ramadhan Rosa Juwita Hesturini Tri Puji Lestari Venty Suryanti Wahyuni, Sri Yuyun Nikmatus Sholicha Yuyun Wulandari