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ANTIOKSIDAN VITAMIN C DAN E MEMBERI PERLINDUNGAN TERHADAP ELASTISITAS SEL DARAH MERAH SELAMA PENYIMPANAN DARAH DONOR Mumpuni, Nurpuji; Supadmi, Francisca Romana Sri; Tongkasi, Siti Munifa; Fauzi, Ahmad
Syifa'Medika Vol 11, No 2 (2021): Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan
Publisher : Faculty of Medicine

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32502/sm.v11i2.2815

Abstract

Selama proses penyimpanan di bank darah, sel darah merah akan berkurang elastisitasnya, sehingga akan menurunkan kualitas darah dalam menjalankan fungsinya. Vitamin C dan vitamin E adalah antioksidan yang dapat menekan stres oksidatif dan radikal bebas. Tujuan dari penelitian ini untuk membuktikan pengaruh pemberian vitamin C dan vitamin E dalam mempertahankan elastisitas sel darah dalam darah donor yang disimpan di UTD (Unit Tranfusi Darah) dan BDRS (Bank Darah Rumah Sakit). Penelitian dilakukan dengan membuat 4 perlakuan darah donor sebagai berikut: (1) kontrol, (2) perlakuan dengan pemberian vitamin C (10.8 mmol/L), (3) perlakuan dengan pemberian vitamin E (21,34 mg/L), serta (4) perlakuan dengan pemberian kombinasi vitamin C (10.8 mmol/L) dan E (21,34 mg/L). Pengamatan dilakukan pada hari pertama minggu ke 1,2,3 dan 4, penyimpanan darah donor baik pada kelompok perlakuan maupun kontrol. Masing-masing sampel diukur jumlah sel darah merah serta kadar hemolisisnya sebelum dan sesudah sampel dilewatkan pada alat filtrasi. Preparat apus darah dan pengamatan mikroskop dibuat pada saat sebelum dan sesudah filtrasi pada minggu ke-1 dan ke-4. Analisis data dilakukan secara deskriptif. Hasil penelitian menunjukkan bahwa pemberian vitamin C dan E sebagai antioksidan memberikan perlindungan untuk mempertahankan elastisitas sel darah merah selama penyimpanan darah donor. Pemberian kombinasi vitamin C dan E menunjukkan hasil yang lebih baik dari pada hanya pemberian vitamin C atau E saja. Proteksi vitamin C terhadap elastisitas sel darah merah lebih baik dibandingkan vitamin E.
PENGARUH PEMBERIAN VITAMIN C DAN E TERHADAP LAJU HEMOLISIS SELAMA PENYIMPANAN DARAH DONOR Ni Luh Cherlin, Juvistha Gabriela Junus, Nurpuji Mumpuni, Francisca Romana SS,
Prosiding Seminar Nasional Multidisiplin Ilmu Vol 3, No 1 (2021): Strategi Mempertahankan Kualitas Penelitian dan Publikasi di Era Pandemi
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Tingkat hemolisis merupakan salah satu parameter kualitas darah donor. Selama proses penyimpanan darah, sel darah merah akan mengalami stres oksidatik dan kerusakan sel yang berakhir dengan hemolisis atau pecahnya sel darah merah. Vitamin C dan E merupakan antioksidan yang dipercaya dapat menekan stress oksidatif dan kerusakan sel. Tujuan penelitian ini adalah untuk melihat pengaruh pemberian Vitamin C dan E terhadap laju hemolisis selama penyimpanan darah donor. Pada penelitian ini dilakukan 4 perlakuan sebagai berikut:(1) Kontrol; (2) perlakuan dengan pemberian Vitamin C; (3) perlakuan dengan pemberian Vitamin E; (4) perlakuan dengan pemberian kombinasi Vitamin C dan E. Uji hemolisis dilakukan pada hari ke 0 (sebelum perlakuan) , 1, 7, 14, 21 dan 28 penyimpanan darah donor. Hasil penelitian menunjukkan bahwa pada dari 1 - 14 laju hemolisis nampak bervariasi antar perlakuan, dimana pemberian perlakuan kombinasi Vitamin C dan E paling baik dalam menekan laju hemolisis. Mulai hari ke-15 sampai 28, terjadi kenaikan laju hemolisis secara signifikan pada semua kelompok, namun laju hemolisis tetap dapat ditekan pada kelompok perlakuan. Perlkuan kombinasi Vitamin C dan E menunjukkan hasil yang terbaik karena disamping Vitamin C dan E merupakan antioksidan, vitamin C juga merupakan penunjang kerja vitamin E. Hasil penelitian menunjukkan pemberian Vitamin C, E serta kombinasi Vitamin C dan E dapat menekan laju hemolisis selama penyimpanan darah donor.
Perbandingan Jumlah Donasi Darah Sebelum dan Saat Pandemi Covid-19 di UTD PMI Banyumas Tahun 2019 dan 2020 Ahmad Fauzi; Francisca Romana Sri Supadmi; Nurpuji Mumpuni
Jurnal Surya Medika (JSM) Vol 7 No 1 (2021): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v7i1.2372

Abstract

Blood donation is someone who voluntarily gives blood; then, the feasibility is processed and transfused to patients in need. Blood donors come from voluntary blood donors or substitute donors/families or certain communities. The COVID-19 pandemic is the spread of a coronavirus epidemic that has spread to various continents and countries. This research is a quantitative descriptive study with a time approach used as a retrospective. The number of donations before the pandemic was 18,661, the number of donations during the pandemic was 22,882, and media for disseminating information using the Whatsapp application. The increase in the number of blood donations during the COVID-19 pandemic and the efforts made to keep donors from donating blood during the COVID-19 pandemic.
Distribusi Komponen Darah Thrombocyte Concentrate (TC) Gina Almirah; Nurpuji Mumpuni; Fransisca Romana Sri Supadmi
Jaringan Laboratorium Medis Vol 2, No 2 (2020): November 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i2.7669

Abstract

Blood transfusions become an important component in the management of patients with injuries to cases of accidents, surgical conditions, violence, pregnancy complications, anemia, hemodialysis, and other medical conditions. The blood transferred can be complete blood and blood components such as Packed Red Cells (PRC), Thrombocyte Concentrate (TC), Anti hemophilia Factor (AHF)/Cryoprecipitate, Fresh Frozen Plasma (FFP), Buffy Coat (BC), Liquid Plasma (LP). This research aims to determine the distribution of blood component Thrombocyte Concentrate (TC) in Indonesian Red Cross Blood Transfusion Service Pontianak City. The design of this research is a quantitative study with a descriptive design, the approach of time used is retrospective by collecting and processing all the distribution data of blood component Thrombocyte Concentrate (TC) in Indonesian Red Cross Blood Transfusion Service Pontianak City in 2019. Processing and analyzing data in this study using the Statistical Product and Service Solutions (SPSS) application. Data analysis results of the number of Thrombocyte Concentrate requests 5,427 bags in 12 months, with an average (Mean) of 452.25 and a data spread (Std. Deviation) of 224.620 is greater than the dosage amount and the distribution of Thrombocyte Concentrate 3,444 bags in 12 months, with an average (Mean) 287 and a data spread (Std. Deviation) 79.681. The most demand and distribution is Dr. Soedarso country general hospital, while the fewest are the Nabasa maternity hospital. The distribution of Thrombocyte Concentrate blood components in Indonesian Red Cross Blood Transfusion Service Pontianak City still needs improvement for both inventory and distribution to be fulfilled the number of Thrombocyte Concentrate requests.
GAMBARAN FAKTOR-FAKTOR PENYEBAB KETIDAKLAYAKAN CALON PENDONOR DARAH DI UDD PMI KABUPATEN BANYUMAS TAHUN 2022 Amanda Descia; Nur'Aini Purnamaningsih; Nurpuji Mumpuni
Jurnal Kesehatan Tambusai Vol. 4 No. 3 (2023): SEPTEMBER 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v4i3.16767

Abstract

Upaya pemenuhan kebutuhan darah yang dilakukan pada kegiatan pelayanan darah salah satunya dengan mempertimbangkan kelayakan pada pendonor darah melalui tahap seleksi donor untuk menentukan layak donor dan tidak layak donor. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan pendekatan retrospektif. Populasi dalam penelitian ini yaitu seluruh pendonor di Unit Donor Darah PMI Kabupaten Banyumas tahun 2022 sebanyak 101.841. Sampel dalam penelitian ini difokuskan pada calon pendonor darah yang tidak layak donor sebanyak 31.510. Teknik pengambilan sampel menggunakan teknik total sampling. Hasil penelitian menunjukkan bahwa jumlah calon pendonor sebanyak 101.841, dimana  calon pendonor darah yang tidak layak donor sebanyak 31.510. Calon pendonor darah yang tidak layak usia  >65 tahun lebih banyak pada mobile unit yaitu 15 (100%), berat badan <45 kilogram lebih banyak pada mobile unit yaitu 111 (100%), tekanan darah tinggi lebih banyak di dalam gedung yaitu 829 (60,21%), tekanan darah rendah lebih banyak pada mobile unit yaitu 4.432 (65,24%), kadar hemoglobin tinggi lebih banyak di dalam gedung yaitu 1.209 (23,80%) dan kadar hemoglobin rendah lebih banyak pada mobile unit yaitu 9.597 (80,15%) calon pendonor darah, berdasarkan faktor kondisi medis meliputi konsumsi obat, tato, bekam, haid, oprasi/bedah, vaksin, sakit, cabut gigi, berpergian luar kota, confirm, belum waktunya donor dan kondisi medis lainya mayoritas terbanyak pada konsumsi obat pada mobile unit yaitu 1.281 (84,28%) calon pendonor darah. Faktor penyebab ketidaklayakan calon pendonor darah di Unit Donor Darah PMI Kabupaten Banyumas tahun 2022 meliputi faktor usia, berat badan, tekanan darah, kadar hemoglobin dan kondisi medis. Mayoritas faktor penyebab ketidaklayakan calon pendonor darahh disebabkan oleh kadar hemoglobin rendah.
Efektivitas Edukasi Donor Darah Melalui Media Video pada Keluarga Pelajar Mahasiswa Indonesia Bolaang Mongondow Raya Yogyakarta Srinopiyanti Labeddu; Nurpuji Mumpuni; Nur'Aini Purnamaningsih
Jurnal Sains & Kesehatan Vol 2 No 2 (2023): Jurnal Sains dan Kesehatan
Publisher : Politeknik Baubau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57151/jsika.v2i2.249

Abstract

The limited number of donors can be caused by a lack of information about blood donors. Knowledge is one aspect of knowing human behavior. To increase students' knowledge, they need a learning media that can describe real physical concepts such as video education. The objective of this study was to describe the effectiveness of blood donor knowledge education through video media at the Indonesian Bolaang Mongondow Student Families Raya Yogyakarta. This research was a quantitative descriptive research with a Quasi-Experimental method which was carried out with a pretest-posttest. The sample is 56 respondents and the sample is taken using the Random Sampling technique. The results showed that the level of knowledge about blood donation prior to video education found that the respondents classified as having a good level of knowledge, 15 people (26.8%), enough 26 people (46.4%), less 15 people (26.8%). While the level of knowledge of blood donors after educational video knowledge was good for 45 people (80.4%), enough for 10 people (17.9%) and less for 1 person (1.8%). The pretest average value of 56 respondents was 65.11 and the posttest average value was 88.59. The effectiveness of video education based on gender characteristics obtained very small results, namely men (difference in the mean pretest and posttest 24.85) and women (difference in the average pretest and posttest 24.24) it can be said that video education is not influenced by gender sex. Based on the characteristics of the most effective age 21-25 years (difference in the average pretest and posttest 23.97) can be said to be influenced by age. Based on the characteristics of the most effective level of education SMA/SMK (difference in the average pretest and posttest of 35) it can be said that it is influenced by the level of education. The results of the paired t test showed that there were significant differences in the level of knowledge about blood donors before and after education using video media with the Sig value obtained. 0.000. Education on blood donor knowledge through videos is effective in increasing knowledge about blood donation.
Pengaruh Konsumsi Makanan terhadap Status Kesehatan Lansia Unjaya Tahun 2023 Reza Iqbal Suhada; Nurpuji Mumpuni; Rahayu Iskandar
Jurnal Formil (Forum Ilmiah) Kesmas Respati Vol 9, No 1 (2024)
Publisher : Universitas Respati Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35842/formil.v9i1.529

Abstract

Peningkatan angka harapan hidup menunjukkan adanya peningkatan jumlah penduduk lanjut usia, yaitu penduduk yang berusia di atas 60 tahun. Lansia merupakan tahapan akhir dalam proses kehidupan yang terjadi akibat banyaknya kemunduran dan perubahan mulai dari fisik, psikis, sosial yang saling berkaitan satu sama lain, sehingga berpotensi menimbulkan gangguan kesehatan fisik dan mental pada lansia. Kampus Unjaya mempunyai program kegiatan yang dilakukan para lansia dalam menjaga kesehatan tubuhnya, yaitu dengan melakukan kegiatan senam dan pemeriksaan kesehatan. Pemeriksaan kesehatan yang dilakukan adalah pemeriksaan glukosa, kolesterol dan asam urat. Pemeriksaan ini dapat dijadikan sebagai penentu status kesehatan lansia. Hasil analisis data pengaruh konsumsi makanan terhadap status kesehatan lansia menunjukkan bahwa nilai p-value > α. Sehingga dapat disimpulkan tidak terdapat pengaruh yang signifikan antara perilaku konsumsi makanan terhadap status kesehatan lansia Unjaya.
Produksi Darah Dan Karakteristik Pendonor Darah Berdasarkan Golongan Darah ABO Dan Rhesus Di UTD PMI Kota Yogyakarta Tahun 2019 Putri, Arum Sari Dwi; Supadmi, Francisca Romana Sri; Mumpuni, Nurpuji
Proceeding Universitas Muhammadiyah Yogyakarta Graduate Conference Vol. 1 No. 1 (2020): Armoring the Youth to Contribute to the SDGs
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.695 KB)

Abstract

Blood type is a unique characteristic of blood in individuals because of the different kinds of carbohydrates and proteins on the surface of red blood cell membranes which classified into blood type A, B, O, and AB. In addition to proteins A and B, there is a factor of rhesus blood type that is positive and negative. Suitability of blood types are very crucial when used for blood transfusion purposes. Proper grouping of blood groups can minimize the risk of transfusion reactions to recipients. This research identifies the blood production and characteristics of blood donor based on the ABO blood group and Rhesus, gender, age, and donor type in the Blood Transfusion Service of Yogyakarta’s Indonesian Red Cross in 2019. The design of research is descriptive retrospective. The result of this study is the majority of blood groups production is O Rh+ 17.165 (37,23%) and O Rh- 47 (0,10%), while the fewest is AB Rh+ 3.567 (7,73%) and AB Rh- 1 (0,00%). The result of this study is the majority of blood groups production is O Rh+ 17.165 (37,23%) and O Rh- 47 (0,10%), while the fewest is AB Rh+ 3.567 (7,73%) and AB Rh- 1 (0,00%). The majority of the blood donor’s gender is male 35.721 (77,47%), for female 10.388 (22,53%). The majority of the blood donor’s age is 18-24 years old 13.335 (28,92 %); the fewest is 17 years old 317 (0,69%). The majority of the type of donor is routine voluntary blood donors 33.602 (72,88%) and new voluntary blood donors 12.507 (27,12%) from 46.109 blood donors.
Pembentukan Kader Ceria (Cerdas Mencegah Anemia) Pada Remaja, Yogyakarta Astuti, Yuli; Artini, Dyah; Mumpuni, Nurpuji
Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Vol 5 No 2 (2025): Desember
Publisher : FKM UIN Sumatera Utara Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/shihatuna.v5i2.25875

Abstract

Anemia is a health problem that is still an important indicator of health status in society. Anemia is a condition where hemoglobin levels are less than normal (<12.5-17.0 gr/dl). Vulnerable groups who experience anemia in society are women and teenagers. Adolescents are at risk of losing iron, because in adolescents there is a growth process that requires an increased need for iron. This community service aims to create cadres to prevent anemia among teenagers. The method of implementing this service is carried out in several stages including coordination with partners, formation of Ceria cadres, cadre development, and socialization of Ceria cadres. The results of this service were that 13 Ceria Cadres underwent anemia screening and Ceria Cadre coaching. The results of the anemia screening showed that 38.46% had anemia, the majority on the pretest questionnaire had sufficient knowledge (53.85%), the posttest had good knowledge (100%) and the evaluation of hemoglobin levels after coaching was 100% normal. The conclusion is that there is an increase in knowledge and hemoglobin levels in Ceria Cadres after coaching.
Distribusi Komponen Darah Thrombocyte Concentrate (TC) Almirah, Gina; Mumpuni, Nurpuji; Supadmi, Fransisca Romana Sri
Jaringan Laboratorium Medis Vol. 2 No. 2 (2020): November 2020
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v2i2.7669

Abstract

Blood transfusions become an important component in the management of patients with injuries to cases of accidents, surgical conditions, violence, pregnancy complications, anemia, hemodialysis, and other medical conditions. The blood transferred can be complete blood and blood components such as Packed Red Cells (PRC), Thrombocyte Concentrate (TC), Anti hemophilia Factor (AHF)/Cryoprecipitate, Fresh Frozen Plasma (FFP), Buffy Coat (BC), Liquid Plasma (LP). This research aims to determine the distribution of blood component Thrombocyte Concentrate (TC) in Indonesian Red Cross Blood Transfusion Service Pontianak City. The design of this research is a quantitative study with a descriptive design, the approach of time used is retrospective by collecting and processing all the distribution data of blood component Thrombocyte Concentrate (TC) in Indonesian Red Cross Blood Transfusion Service Pontianak City in 2019. Processing and analyzing data in this study using the Statistical Product and Service Solutions (SPSS) application. Data analysis results of the number of Thrombocyte Concentrate requests 5,427 bags in 12 months, with an average (Mean) of 452.25 and a data spread (Std. Deviation) of 224.620 is greater than the dosage amount and the distribution of Thrombocyte Concentrate 3,444 bags in 12 months, with an average (Mean) 287 and a data spread (Std. Deviation) 79.681. The most demand and distribution is Dr. Soedarso country general hospital, while the fewest are the Nabasa maternity hospital. The distribution of Thrombocyte Concentrate blood components in Indonesian Red Cross Blood Transfusion Service Pontianak City still needs improvement for both inventory and distribution to be fulfilled the number of Thrombocyte Concentrate requests.