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All Journal Disease Prevention and Public Health Journal Jurnal Farmasi Klinik Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) Journal Syifa Sciences and Clinical Research (JSSCR) Sasambo Journal of Pharmacy Jurnal Ilmiah Sains Jurnal Yoga Dan Kesehatan Jurnal Mitrasehat Jurnal Novem Medika Farmasi
Hasanuddin, Rusman
Universitas Islam Makassar
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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FORMULASI DAN EVALUASI SABUN TRANSPARAN EKSTRAK BIJI KOPI HIJAU ROBUSTA SEBAGAI TERAPI ULKUS DIABETIK Nur Zalzabila Ramli; Uswatun Hasanah; Amelia Triwardhani; Rusman
Jurnal Mitrasehat Vol. 15 No. 3 (2025): Jurnal Mitrasehat
Publisher : LPPM STIK Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51171/jms.v15i3.568

Abstract

Latar belakang: Kopi biji hijau robusta terdapat kafein selain itu juga terdapat asam klorogenat yang dimana dapat menstabilkan kadar gula di dalam darah dan dapat mengurangi penyerapan kadar glukosa serta meningkatkan sensitivitas insulin. Kami berinovasi untuk membuat sabun transparan dengan ekstrak biji kopi hijau robusta. Tujuan: Untuk mengetahui karakteristik dari sabun transparan. Metode: Jenis metode yang digunakan yaitu metode analisis kualitatif dengan menggunakan pendekatan grounded theory. Hasil: Berdasarkan dari hasil yang diperoleh sabun transparan memiliki wangi bunga lily, tekstur sedikit keset dan berwarna hijau dari ektark biji kopi hijau robusta sehingga transparasi tidak terlihat sangat jelas, busa yang di dapatkan telah sesuai dengan standar SNI begitupun dengan pH. Kesimpulan: Sabun tersebut berpotensi menjadi inovasi dalam mengembangkan sabun transparan dengan menggunakan pewarna alami dari ekstrak biji kopi hijau robusta dengan memperhatikan transparasi dari sabun tersebut.
Effect of Giving Ethanol Extract of Robusta Coffee Beans (Coffea canephora Pierre ex A. Froehner) Based on Immunohistochemical Examination of GLUT-4 Protein Expression in White Rats (Rattus norvegicus) Model of Diabetes Mellitus Jasmiadi; Rusman; Alim, Nur; Rahma, Tarisa Jabal
Jurnal Penelitian Pendidikan IPA Vol 11 No 8 (2025): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i8.12044

Abstract

Metabolic disorders are characterized by an increase in blood sugar due to a decrease in insulin secretion by pancreatic beta cells. Cells are unable to stimulate glucose absorption in muscle and fat tissue. The presence of GLUT-4 can increase the rate of glucose entry into insulin target tissues. The chlorogenic acid compound in robusta coffee beans is believed to lower blood glucose levels by activating GLUT-4. The aim of the research was to determine the effect of administering ethanol extract of robusta coffee beans (Coffea canephora Pierre ex A. Froehner) based on immunohistochemical examination of GLUT-4 protein expression in mice (Rattus norvegicus) with Type 2 Diabetes Mellitus. The research method included extraction by maceration with 96% ethanol: distilled water (3:7) solvent and immunohistochemical testing of the effect of ethanol extraction of Robusta coffee beans on mice. Rats were divided into 5 treatment groups, namely, Na-CMC 1%, metformin, 150 mg/kg BB, 300 mg/kg BB and 450 mg/kg BB and fed a high-fat diet for 6 months and immunohistochemical examination of skeletal muscle tissue was carried out. The results of immunohistochemical examination found that protein expression occurred in the positive control of coffee bean ethanol extract at doses of 150 mg/kg BB, 300 mg/kg BB and 450 mg/kg BB. The statistical test results show that the ethanol extract of robusta coffee beans at doses of 150 mg/kg BB, 300 mg/kg BB and 450 mg/kg BB is significant with the negative control      Na-CMC 1% but with the positive control metformin the three doses of ethanol extract of robusta coffee beans are not significant. From the discussion above, it can be concluded that the ethanol extract of robusta coffee beans has an effect at doses of 300 mg/kg BB and 450 mg/kg BB
Co-Authors A. Ihdinal Hagg Abdillah, Nurliana Ahmad Fauzan Amelia Triwardhani Amelia Triwardhani, Amelia Triwardhani Amelia Triwardhani, Uswatun Hasanah Arfiani Arifin Armita Aprisa Aulia Aulia Besse Yuliana ekawati gusman, Aswi warfa gusman Hardi, Samsu Irfayanti, Nur Alfiah Jasmiadi Jasmiadi Jasmiadi Jasmiadi, Jasmiadi Karnidayanti Karnidayanti Muhammad Ihsan Muhammad Irhas, Muhammad Musdalifah Musdalifah Ni Ketut Sinarsih Nur Alfiah Irfiyanti Nur Alim Nur Linda Nur Zalzabila Ramli Nurliana Abdillah Pratama, Agus Sangka Rahma, Tarisa Jabal Ramli, Nur Zalzabila Rizki Rahmawati, Rizki Sangadji, Rahima Sri Sulistyawati Anton Syamsiar Tahirah Hasan USWATUN HASANAH Zulfitri Zulfitri