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All Journal Jurnal Pengajaran MIPA Dimas: Jurnal Pemikiran Agama untuk Pemberdayaan Jurnal Kimia dan Kemasan Biology, Medicine, & Natural Product Chemistry Journal of Islamic Studies and Humanities JC-T (Journal Cis-Trans): Jurnal Kimia dan Terapannya Al-Kimia Walisongo Journal of Chemistry Jambura Journal of Chemistry Social, Humanities, and Educational Studies (SHEs): Conference Series Reswara: Jurnal Pengabdian Kepada Masyarakat Jurnal Kimia dan Kemasan Prosiding Seminar Nasional Pendidikan dan Agama Dinamika Sosial: Jurnal Pengabdian Masyarakat Dan Transformasi Kesejahteraan
Hafshah, Mutista
UIN Walisongo Semarang
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Other

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Journal : Al-Kimia

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Potential of Secang Wood (Caesalpinia sappan L.) Ethanol Extractas Anti-Oxidant and Sun-Protection Hafshah, Mutista; Rohmah, Alfiatu; Mardliyah, Ana
Al-Kimia Vol 10 No 2 (2022): DECEMBER
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v10i2.28619

Abstract

Although sunlight has numerous health benefits, prolonged direct exposure to the sun can be harmful to the skin. Among the negative effects of sun exposure are redness and burning of the skin, as well as dullness, wrinkles, dryness, and premature aging, as well as skin cancer. The use of sunscreen to protect the skin from the harmful effects of prolonged sun exposure is becoming more widespread. On the other hand, some sunscreens contain potentially harmful chemicals such as isopropyl alcohol, DEA (diethanolamine), TEA (triethanolamine), and MEA (monoethanolamine), which can cause allergic reactions as well as kidney and liver disorders when used for an extended period of time. As a result, this investigation was carried out in order to determine the antioxidant potential of natural ingredients, specifically sappan wood (Caesalpinia sappan L.), using the DPPH method, as well as its potential as a sun-protective agent using an in vitro SPF test using ultraviolet-visible (Uv-Vis) spectrophotometry (Uv-Vis). The results revealed that the maceration method produced a 17.779 percent yield of ethanol extract of sappan wood, which was used in this study. The extract possesses extremely potent antioxidant activity, as evidenced by its IC50 value of 12,611 mg/L. Furthermore, based on the results of tests and the calculation of the SPF (sun protection factor) value, sappan wood extract has been shown to have potential as a sun protection agent. Using an extract concentration of 120 mg/L, the highest SPF value.
Antibacterial Activity Test of Secang Wood (Caesalpinia sappan L.) Ethanol Extract Against Streptococcus mutans Listiani, Febri Intan; Hafshah, Mutista; Latifah, Rais Nur
Al-Kimia Vol 11 No 1 (2023): JUNE
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v11i1.37136

Abstract

Dental caries is caused by the Streptococcus mutans bacteria, which causes a food deposit to harden and adhere to the tooth surface. Cavities will develop if food residue is not removed. Herbal plants, specifically sappan wood, can be used as an antibiotic. The purpose of this study was to look at the secondary metabolite content of sappan wood extract, antibacterial activity, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of sappan wood extract against Streptococcus mutans bacteria. This research method includes the maceration of sappan wood extract with 96% ethanol solvent, phytochemical screening of sappan wood extract, inhibition zone test with paper disc method, and MIC and MBC tests. Qualitative testing revealed that the sappan wood extract contained alkaloids, flavonoids, tannins, and saponins. Flavonoids, tannins, and saponins are all constituents of plants. Secang wood extract has antibacterial activity against Streptococcus mutans, as evidenced by the formation of inhibition zones at concentrations of 20%, 40%, 60%, 80%, and 100%, namely 8.75±0.354; 11±1.41;, 12.75±0.354; 16.25±0.354; and 17.5±0.000 mm. Sappan wood ethanol extract had a MIC of 12.5% against Streptococcus mutans and an MBC of 25%.
Co-Authors Ahmad Zubaeri Akbar, Achmad Amin, Ahmad Faqih Amrizarois Ismail Ana Mardliyah Azza Lathifah Chusnah, Hudallil Eka Intansari Eva Vaulina Yulistia Delsy Faiz, Rijal Akhmad Firdaus, Irvan Maulana Hashona, Achmad Hasmy Ika Nur Fitriani Ismail, Amrizarois Khoirin Nida Kholidah Kholidah, Kholidah Lilis Karlina Lilis karlina, Lilis Listiani, Febri Intan Mochammad Chasani Muhammad Faza Nasrullah Muhammad Hanafi Nana Misrochah Niamul Faza Assauqi NIDA, KHOIRIN NURUL HIDAYAH Ponco Iswanto Rais Nur Latifah Rohmah, Alfiatu Satriya, Daffa Faiq Aji Sri Mulyanti Supitayanti Supitayanti Teguh Wibowo Tika Rahmawati Titin Kartin