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Journal : Pharmaceutical Science Journal

TINGKAT KEPATUHAN PASIEN TUBERKULOSIS PARU PADA PENGGUNAAN OBAT ANTI TUBERKULOSIS DI PUSKESMAS CIPAYUNG KOTA DEPOK Agung Dewantoro; Aulia Nadya Rizki Imansari; Ahmad Fadhila
PHRASE (Pharmaceutical Science) Journal Vol 2, No 2 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 2 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i2.400

Abstract

Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis, which can attack the lungs and other organs. Transmission occurs when a person inhales droplet nuclei that enter through the mouth or nose, upper respiratory tract and bronchi until they reach the lungs. One of the determinants of success in the treatment of pulmonary TB is that the patient must improve compliance in taking anti-tuberculosis drugs obediently and regularly until complete. There are several factors that influence the level of adherence to the use of anti-tuberculosis drugs in patients with pulmonary TB, namely motivation, family support, supervision from PMO, education level and occupation. This study aims to determine the level of adherence to the use of anti-tuberculosis drugs in pulmonary TB patients at the Cipayung Health Center. The type of research used is descriptive by using the total sampling method and the sample used is 28 respondents. Data were collected using a validated questionnaire based on the MMAS-8 (Morisky Medication Adherence Scale). The results of this study were (57%) male samples, (36%) were early adults between 26-35 years old, (57%) had high school education, (53.5%) worked as private employees. And the results obtained (82%) have a high level of compliance, (14%) have a moderate level of compliance, and (4%) have a low level of compliance. The conclusion from the level of adherence to the use of anti-tuberculosis drugs in pulmonary TB patients at the Cipayung Health Center with a value (82%) has a high level of adherence as many as 23 respondents.
KESESUAIAN PENYIMPANAN GOLONGAN NARKOTIKA DAN PSIKOTROPIKA DI FARMASI RUMAH SAKIT X DAERAH KEBAYORAN BARU JAKARTA SELATAN sayyidah sayyidah; Agung Dewantoro; Bheta Sari Dewi; Ahmad Sopian
PHRASE (Pharmaceutical Science) Journal Vol 2, No 1 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 1 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i1.182

Abstract

The hospital is one of the facilities that provide health services in an effort to maintain, improve health, prevent disease, cure disease, and recovering. Pharmaceutical services in hospitals have standards that must be met, namely regarding clinical pharmacy services and drug management. The formulation of the problems in this research are: How is the level of suitability for storing narcotics and psychotropic drugs at the Pertamina Central Hospital (RSPP) based on the Regulation of the Minister of  Health Number 3 of  2015. This research uses a descriptive type, which is the most basic form of research. Intended to describe existing phenomena. This research examines the forms, activities, characteristics, changes, relationships, similarities, and differences between them and other phenomena. The results of this study indicate that the suitability of narcotics and psychotropic drugs is said to be good, the death stock of narcotics and psychotropic drugs is said to be good. The percentage of narcotics and psychotropic drugs that are expired or damaged are said to be good. The suitability of the Narcotics and Psychotropic drug dispensing system is not 100% FIFO and FEFO. The psychotropic storage system at the Pertamina Central Hospital Pharmacy Installation has met the Storage Standards based on the guidelines for the management of Hospital Pharmaceutical Supplies and the Regulation of the Minister of Health of the Republic of Indonesia Number 3 of 2015.
PROFIL PERESEPAN OBAT ASMA PADA PASIEN ANAK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT “X” JAKARTA PERIODE JANUARI – MARET 2023 Dewantoro, Agung; Fahriati, Andriyani Rahmah; Galih Pratiwi, Rekiyan Tuhu; Dewi, Bheta Sari; Rahajeng, Suny Koswara; Ismaya, Nurwulan Adi
PHRASE (Pharmaceutical Science) Journal Vol 4, No 1 (2024): Pharmaceutical Science Journal Vol 4 No 1, 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i1.730

Abstract

Asma merupakan penyakit inflamasi (peradangan) kronis saluran napas yang ditandai dengan adanya mengi episodik, batuk, dan rasa sesak di dada akibat penyumbatan saluran napas. Asma pada bayi dan anak-anak memiliki angka kejadian yang lebih tinggi dibandingkan pada orang dewasa. Asma pada anak juga memiliki angka morbiditas dan mortalitas yang lebih tinggi dibandingkan orang dewasa. Penyakit asma tidak dapat disembuhkan namun dapat di kontrol sehingga pasien anak yang menderita asma akan mengkonsumsi atau menggunakan obat obatan asma dalam kurun waktu yang cukup panjang. Disamping itu serangan asma yang tidak dapat terprediksi serta munculnya sesak napas pada pasien asma dapat menyebabkan kematian apabila tidak ditangani dengan cepat. Oleh karenannya obat asma harus selalu tersedia dan tidak boleh terjadi kekosongan disarana pelayanan kesehatan sehingga pola peresepan obat asma pada pasien anak perlu diketahui agar data yang diperoleh dapat digunakan sebagai evaluasi pengadan obat asma pada pasien anak agar tidak terjadi kekosongan  Tujuan : Penelitian ini bertujuan untuk mengetahui profil peresepan obat asma pada pasien anak di instalasi farmasi rawat jalan Rumah Sakit “X” di wilayah Jakarta Selatan. Metode : Penelitian ini merupakan penelitian non eksperimental dengan rancangan penelitian bersifat deskriptif. Metode penelitian ini dilakukan dengan pendekatan kuantitatif dengan pengambilan data secara retrospektif dengan menggunakan data rekam medis pasien asma anak secara retrospektif pada periode Januari – Maret 2023 di instalasi farmasi rawat jalan Rumah Sakit “X” di wilayah Jakarta Selatan. Hasil :  penelitian ini menunjukkan bahwa mayoritas pasien asma adalah anak laki-laki sebanyak 56 orang (57,73%) dengan usia 0 – 4 tahun sebanyak 53 (54,64%). Jenis obat bronkodilator yang paling banyak digunakan adalah salbutamol (54,69%), golongan kortikostreroid menggunakan obat jenis budesonide (46,47%), antihistamin yaitu cetirizine (68,18%), mukolitik yaitu acetylcysteine (36%), dan analgetik antipiretik yaitu paracetamol (100%). Golongan obat asma yang paling banyak digunakan yaitu golongan bronkodilator (46,21%). Bentuk sediaan obat yang paling banyak diresepkan adalah nebulizer (35%). Jumlah obat asma dalam 1 resep yang paling banyak diresepkan yaitu 2 macam obat (34,02%).
PROFIL PERESEPAN OBAT ANTI TUBERKULOSIS PADA PASIEN ANAK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT X BOGOR PERIODE JANUARI – MARET 2023 Dewantoro, Agung; Andriati, Riris; Haryani, Setianti; Sakinah, Nur; Dewi, Bheta Sari; Rahajeng, Suny Koswara; Ismaya, Nurwulan Adi
PHRASE (Pharmaceutical Science) Journal Vol 3, No 2 (2023): Pharmaceutical Science Journal Vol 3 No 2, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i2.609

Abstract

Childhood tuberculosis is a disease caused by Mycobacterium tuberculosis at the age of 0-11 years. In Indonesia, tuberculosis is the third leading cause of death after cardiovascular disease and respiratory disease in all age groups. Tuberculosis in children is the most important factor in developing countries because the number of children aged 15 years is 40-50% of the total population. Objective: To find out the Prescribing Profile of Anti-Tuberculosis Drugs in Pediatric Patients at the Bogor X  Hospital Outpatient Pharmacy Installation for the January – March 2023 period. Methods: The type of research conducted was a non-experimental study with a descriptive research design. This research method was carried out using a quantitative approach and retrospective data collection. The retrospective approach is a study that looks backwards, which means collecting data from medical records with a diagnosis of tuberculosis. Results: This study showed that of the 94 tuberculosis patients at Bogor X  Hospital, the dominant sex was male (55.4%), with an age range of 0-5 years (65.9%), with an anatomical location of the disease in pulmonary tuberculosis (91.4%), with treatment for 6 months (95.7%) with comorbid dyspepsia (29.6%), with an intensive treatment phase, namely anti-tuberculosis drugs (66%), with an advanced treatment phase, namely anti-tuberculosis drugs (72.8%) and the use of other drugs, namely vitamins (72.8%).
FORMULASI DAN EVALUASI AKTIVITAS ANTIOKSIDAN SABUN CAIR BERBAHAN DASAR EKSTRAK DAUN KEMANGI DAN MADU Dewi, Bheta Sari; Utami, Sheila Meitania; Werawati, Ayu; Bachtiar, Wahyu; Dewantoro, Agung
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.903

Abstract

Basil leaves  (Ocimum sanctum L.) and honey contain flavonoids and polyphenol compounds such as methyl eugenol, which are known to have antioxidant activity. Liquid soap is a form of pharmaceutical product that is often used to cleanse the body and provide additional protection to the skin. Objective: The aim of this study was to obtain the best physical formulation of a liquid soap combination of basil leaf extract and honey and its antioxidant activity. Method: Liquid soap preparations were made by adding basil leaf extract with various concentrations of 2g (FI), 4g (FII) and 8g (FIII) and honey, namely 5g (FI), 5g (FII) and 5g (FIII). Evaluation of liquid soap preparations included organoleptic, pH, and homogenity, as well as antioxidant activity test using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method with a wavelength of 516 nm. Results: The results showed that Formula III (FIII) had the best results, namely organoleptic milk chocolate color, pH preparation (9.71-9.89), homogeneous preparation, stable preparation in storage for 12 days and showed the best IC50 value of 118.39 ppm. Conclusion: In conclusion, the combination of basil leaf extract and honey can be formulated as a liquid soap preparation with a concentration of 8g basil leaf extract and 5g honey in formula III (FIII) showing the effectiveness as the best formulation.
PROFIL PRESEPAN OBAT PADA PASIEN PEMBESARAN PROSTAT JINAK ATAU BPH (BENIGN PROSTATIC HYPERPLASIA) TAMSULOSIN DAN DUTASTERIDE DI INSTALASI RAWAT JALAN RUMAH SAKIT “X” CIPUTAT PERIODE OKTOBER-DESEMBER 2024 Dewantoro, Agung; Dewi, Bheta Sari; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 5, No 1 (2025): Vol 5 No 1 : Pharmaceutical Science Journal
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i1.1003

Abstract

Benign prostatic hyperplasia (BPH) is a term used in histopathology to describe the presence of enlarged stromal and epithelial cells in the prostate gland.  In essence, BPH mostly affects elderly men whose testes are still capable of making testosterone. According to earlier research, using dutasteride and tamsulosin together may have greater therapeutic results for BPH and significantly lower the chance that symptoms may worsen. Purpose:  The objective of this study was to identify salient features of Tamsulosin and Dutasteride prescriptions for benign prostatic enlargement (BPH) at Ciputat "X" Hospital's outpatient clinic from October to December 2024.. Methods: This research method is descriptive, the data is taken restropectively, namely research that looks back, meaning data collection from medical records of outpatients with BPH diagnoses. Results: This study showed that, 101 samples of BPH patients were obtained, the most BPH patients occurred at the age of 56-65 (47.5%), the most work status was self-employed (44.6%), the mosttypes oftherapy were combination therapy oftamsulosin with dutasteride (56.4%), α1-blocker drug classes that got a percentage (100%), the most length of therapy was 1 month (98.0%), and other groups of drugs prescribed Antibiotics (37.5%).