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Journal : Pharmaceutical Science Journal

TINGKAT KEPATUHAN PASIEN TUBERKULOSIS PARU PADA PENGGUNAAN OBAT ANTI TUBERKULOSIS DI PUSKESMAS CIPAYUNG KOTA DEPOK Agung Dewantoro; Aulia Nadya Rizki Imansari; Ahmad Fadhila
PHRASE (Pharmaceutical Science) Journal Vol 2, No 2 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 2 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i2.400

Abstract

Tuberculosis is a contagious infectious disease caused by Mycobacterium tuberculosis, which can attack the lungs and other organs. Transmission occurs when a person inhales droplet nuclei that enter through the mouth or nose, upper respiratory tract and bronchi until they reach the lungs. One of the determinants of success in the treatment of pulmonary TB is that the patient must improve compliance in taking anti-tuberculosis drugs obediently and regularly until complete. There are several factors that influence the level of adherence to the use of anti-tuberculosis drugs in patients with pulmonary TB, namely motivation, family support, supervision from PMO, education level and occupation. This study aims to determine the level of adherence to the use of anti-tuberculosis drugs in pulmonary TB patients at the Cipayung Health Center. The type of research used is descriptive by using the total sampling method and the sample used is 28 respondents. Data were collected using a validated questionnaire based on the MMAS-8 (Morisky Medication Adherence Scale). The results of this study were (57%) male samples, (36%) were early adults between 26-35 years old, (57%) had high school education, (53.5%) worked as private employees. And the results obtained (82%) have a high level of compliance, (14%) have a moderate level of compliance, and (4%) have a low level of compliance. The conclusion from the level of adherence to the use of anti-tuberculosis drugs in pulmonary TB patients at the Cipayung Health Center with a value (82%) has a high level of adherence as many as 23 respondents.
KESESUAIAN PENYIMPANAN GOLONGAN NARKOTIKA DAN PSIKOTROPIKA DI FARMASI RUMAH SAKIT X DAERAH KEBAYORAN BARU JAKARTA SELATAN sayyidah sayyidah; Agung Dewantoro; Bheta Sari Dewi; Ahmad Sopian
PHRASE (Pharmaceutical Science) Journal Vol 2, No 1 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 1 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i1.182

Abstract

The hospital is one of the facilities that provide health services in an effort to maintain, improve health, prevent disease, cure disease, and recovering. Pharmaceutical services in hospitals have standards that must be met, namely regarding clinical pharmacy services and drug management. The formulation of the problems in this research are: How is the level of suitability for storing narcotics and psychotropic drugs at the Pertamina Central Hospital (RSPP) based on the Regulation of the Minister of  Health Number 3 of  2015. This research uses a descriptive type, which is the most basic form of research. Intended to describe existing phenomena. This research examines the forms, activities, characteristics, changes, relationships, similarities, and differences between them and other phenomena. The results of this study indicate that the suitability of narcotics and psychotropic drugs is said to be good, the death stock of narcotics and psychotropic drugs is said to be good. The percentage of narcotics and psychotropic drugs that are expired or damaged are said to be good. The suitability of the Narcotics and Psychotropic drug dispensing system is not 100% FIFO and FEFO. The psychotropic storage system at the Pertamina Central Hospital Pharmacy Installation has met the Storage Standards based on the guidelines for the management of Hospital Pharmaceutical Supplies and the Regulation of the Minister of Health of the Republic of Indonesia Number 3 of 2015.
PROFIL PERESEPAN OBAT ASMA PADA PASIEN ANAK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT “X” JAKARTA PERIODE JANUARI – MARET 2023 Dewantoro, Agung; Fahriati, Andriyani Rahmah; Galih Pratiwi, Rekiyan Tuhu; Dewi, Bheta Sari; Rahajeng, Suny Koswara; Ismaya, Nurwulan Adi
PHRASE (Pharmaceutical Science) Journal Vol 4, No 1 (2024): Pharmaceutical Science Journal Vol 4 No 1, 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i1.730

Abstract

Asma merupakan penyakit inflamasi (peradangan) kronis saluran napas yang ditandai dengan adanya mengi episodik, batuk, dan rasa sesak di dada akibat penyumbatan saluran napas. Asma pada bayi dan anak-anak memiliki angka kejadian yang lebih tinggi dibandingkan pada orang dewasa. Asma pada anak juga memiliki angka morbiditas dan mortalitas yang lebih tinggi dibandingkan orang dewasa. Penyakit asma tidak dapat disembuhkan namun dapat di kontrol sehingga pasien anak yang menderita asma akan mengkonsumsi atau menggunakan obat obatan asma dalam kurun waktu yang cukup panjang. Disamping itu serangan asma yang tidak dapat terprediksi serta munculnya sesak napas pada pasien asma dapat menyebabkan kematian apabila tidak ditangani dengan cepat. Oleh karenannya obat asma harus selalu tersedia dan tidak boleh terjadi kekosongan disarana pelayanan kesehatan sehingga pola peresepan obat asma pada pasien anak perlu diketahui agar data yang diperoleh dapat digunakan sebagai evaluasi pengadan obat asma pada pasien anak agar tidak terjadi kekosongan  Tujuan : Penelitian ini bertujuan untuk mengetahui profil peresepan obat asma pada pasien anak di instalasi farmasi rawat jalan Rumah Sakit “X” di wilayah Jakarta Selatan. Metode : Penelitian ini merupakan penelitian non eksperimental dengan rancangan penelitian bersifat deskriptif. Metode penelitian ini dilakukan dengan pendekatan kuantitatif dengan pengambilan data secara retrospektif dengan menggunakan data rekam medis pasien asma anak secara retrospektif pada periode Januari – Maret 2023 di instalasi farmasi rawat jalan Rumah Sakit “X” di wilayah Jakarta Selatan. Hasil :  penelitian ini menunjukkan bahwa mayoritas pasien asma adalah anak laki-laki sebanyak 56 orang (57,73%) dengan usia 0 – 4 tahun sebanyak 53 (54,64%). Jenis obat bronkodilator yang paling banyak digunakan adalah salbutamol (54,69%), golongan kortikostreroid menggunakan obat jenis budesonide (46,47%), antihistamin yaitu cetirizine (68,18%), mukolitik yaitu acetylcysteine (36%), dan analgetik antipiretik yaitu paracetamol (100%). Golongan obat asma yang paling banyak digunakan yaitu golongan bronkodilator (46,21%). Bentuk sediaan obat yang paling banyak diresepkan adalah nebulizer (35%). Jumlah obat asma dalam 1 resep yang paling banyak diresepkan yaitu 2 macam obat (34,02%).
PROFIL PERESEPAN OBAT ANTI TUBERKULOSIS PADA PASIEN ANAK DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT X BOGOR PERIODE JANUARI – MARET 2023 Dewantoro, Agung; Andriati, Riris; Haryani, Setianti; Sakinah, Nur; Dewi, Bheta Sari; Rahajeng, Suny Koswara; Ismaya, Nurwulan Adi
PHRASE (Pharmaceutical Science) Journal Vol 3, No 2 (2023): Pharmaceutical Science Journal Vol 3 No 2, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i2.609

Abstract

Childhood tuberculosis is a disease caused by Mycobacterium tuberculosis at the age of 0-11 years. In Indonesia, tuberculosis is the third leading cause of death after cardiovascular disease and respiratory disease in all age groups. Tuberculosis in children is the most important factor in developing countries because the number of children aged 15 years is 40-50% of the total population. Objective: To find out the Prescribing Profile of Anti-Tuberculosis Drugs in Pediatric Patients at the Bogor X  Hospital Outpatient Pharmacy Installation for the January – March 2023 period. Methods: The type of research conducted was a non-experimental study with a descriptive research design. This research method was carried out using a quantitative approach and retrospective data collection. The retrospective approach is a study that looks backwards, which means collecting data from medical records with a diagnosis of tuberculosis. Results: This study showed that of the 94 tuberculosis patients at Bogor X  Hospital, the dominant sex was male (55.4%), with an age range of 0-5 years (65.9%), with an anatomical location of the disease in pulmonary tuberculosis (91.4%), with treatment for 6 months (95.7%) with comorbid dyspepsia (29.6%), with an intensive treatment phase, namely anti-tuberculosis drugs (66%), with an advanced treatment phase, namely anti-tuberculosis drugs (72.8%) and the use of other drugs, namely vitamins (72.8%).
FORMULASI DAN EVALUASI AKTIVITAS ANTIOKSIDAN SABUN CAIR BERBAHAN DASAR EKSTRAK DAUN KEMANGI DAN MADU Dewi, Bheta Sari; Utami, Sheila Meitania; Werawati, Ayu; Bachtiar, Wahyu; Dewantoro, Agung
PHRASE (Pharmaceutical Science) Journal Vol 4, No 2 (2024): Pharmaceutical Science Journal Vol 4 No 2
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v4i2.903

Abstract

Basil leaves  (Ocimum sanctum L.) and honey contain flavonoids and polyphenol compounds such as methyl eugenol, which are known to have antioxidant activity. Liquid soap is a form of pharmaceutical product that is often used to cleanse the body and provide additional protection to the skin. Objective: The aim of this study was to obtain the best physical formulation of a liquid soap combination of basil leaf extract and honey and its antioxidant activity. Method: Liquid soap preparations were made by adding basil leaf extract with various concentrations of 2g (FI), 4g (FII) and 8g (FIII) and honey, namely 5g (FI), 5g (FII) and 5g (FIII). Evaluation of liquid soap preparations included organoleptic, pH, and homogenity, as well as antioxidant activity test using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method with a wavelength of 516 nm. Results: The results showed that Formula III (FIII) had the best results, namely organoleptic milk chocolate color, pH preparation (9.71-9.89), homogeneous preparation, stable preparation in storage for 12 days and showed the best IC50 value of 118.39 ppm. Conclusion: In conclusion, the combination of basil leaf extract and honey can be formulated as a liquid soap preparation with a concentration of 8g basil leaf extract and 5g honey in formula III (FIII) showing the effectiveness as the best formulation.
PROFIL PRESEPAN OBAT PADA PASIEN PEMBESARAN PROSTAT JINAK ATAU BPH (BENIGN PROSTATIC HYPERPLASIA) TAMSULOSIN DAN DUTASTERIDE DI INSTALASI RAWAT JALAN RUMAH SAKIT “X” CIPUTAT PERIODE OKTOBER-DESEMBER 2024 Dewantoro, Agung; Dewi, Bheta Sari; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 5, No 1 (2025): Vol 5 No 1 : Pharmaceutical Science Journal
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i1.1003

Abstract

Benign prostatic hyperplasia (BPH) is a term used in histopathology to describe the presence of enlarged stromal and epithelial cells in the prostate gland.  In essence, BPH mostly affects elderly men whose testes are still capable of making testosterone. According to earlier research, using dutasteride and tamsulosin together may have greater therapeutic results for BPH and significantly lower the chance that symptoms may worsen. Purpose:  The objective of this study was to identify salient features of Tamsulosin and Dutasteride prescriptions for benign prostatic enlargement (BPH) at Ciputat "X" Hospital's outpatient clinic from October to December 2024.. Methods: This research method is descriptive, the data is taken restropectively, namely research that looks back, meaning data collection from medical records of outpatients with BPH diagnoses. Results: This study showed that, 101 samples of BPH patients were obtained, the most BPH patients occurred at the age of 56-65 (47.5%), the most work status was self-employed (44.6%), the mosttypes oftherapy were combination therapy oftamsulosin with dutasteride (56.4%), α1-blocker drug classes that got a percentage (100%), the most length of therapy was 1 month (98.0%), and other groups of drugs prescribed Antibiotics (37.5%).
Evaluasi Pemberian Informasi Obat Pada Pasien Tuberkulosis Di Rumah Sakit X Periode April 2025 Dewantoro, Agung; Haryani, Setianti; Rahajeng, Suny Koswara
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1083

Abstract

Drug Information Service (PIO) plays a crucial role in treatment success because accurate and precise information regarding drug use greatly supports the effectiveness of therapy. The objective of this study was to evaluate the provision of drug information to TB patients at Hospital X. Methods: This research used a quantitative descriptive design. Data were collected through a questionnaire distributed to 100 respondents selected using an accidental sampling technique based on predetermined inclusion criteria. Results : Treatment duration 4 months 61 respondents (61%), TB anatomical location pulmonary TB 100 respondents (100%), Treatment phase continuation phase 61 respondents (61%), Most commonly prescribed additional drug group vitamins (45.45%), Most commonly prescribed additional drug type Kurkumax on 40 respondent (40%), The provision of PIO services for TB patients at Hospital X was found to be in good condition (91%). Conclusion: The process of providing anti-tuberculosis drug information at Hospital X is categorized as good.
Profil Pengobatan Dan Efektivitas Obat Tuberkulosis Paru Pada Pasien Tuberkulosis Paru Di Puskesmas Kebayoran Lama Rahajeng, Suny Koswara; Sayyidah, Sayyidah; Fadhilah, Humaira; Dewantoro, Agung; Dewi, Bheta Sari; Ardiansyah, Muhammad Rivan
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1180

Abstract

Pulmonary tuberculosis (TB) is a serious health problem in Indonesia. A treatment profile that meets guidelines and patient compliance is crucial for successful therapy. To determine the treatment profile and effectiveness of TB drugs in patients at the Kebayoran Lama Community Health Center. This descriptive study used secondary data from the medical records of 78 pulmonary TB patients selected by purposive sampling from July to December 2024. Analysis was based on patient characteristics, treatment profiles, and drug effectiveness. The results the majority of patients were aged 17-25 years (38%), female (51%), had a high school education (54%), and worked as private sector workers (27%). In the intensive phase, most patients (72%) weighing 55-70 kg received a regimen of 4 tablets of 4FDC; the continuation phase used 4 tablets of 2FDC. The effectiveness of therapy was demonstrated by 54% of patients with negative AFB conversion accompanied by clinical improvement (reduced cough, increased appetite, decreased shortness of breath). The Conclusion is Pulmonary TB treatment at the Kebayoran Lama Community Health Center is in accordance with national guidelines with weight-based dosage. Regular evaluation is still needed to improve the success of therapy.
Analisa Penggunaan Antibiotik Pada Pasien Pneumonia Anak Dan Remaja Di Rs Bhayangkara Lemdiklat Polri Periode Januari-Desember 2024 Nurlela, Nurlela; Dewantoro, Agung; Susanti, Debi; Aulia, Gina
PHRASE (Pharmaceutical Science) Journal Vol 5, No 2 (2025): Pharmaceutical Science Journal Vol 5 No 2, 2025
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v5i2.1174

Abstract

Pneumonia attacks the respiratory tract and is one of the dangerous infections that can potentially cause high mortality rates, especially in children and adolescents. The objective of this study were to analyze the pattern of antibiotics use in pediatric and adolescent pneumonia patients at an inpatient ward, Bhayangkara Lemdiklat Polri Hospital. Methods:This was a descriptive, observational and cross-sectional study. We employed a total sampling method, collecting data from patient medical records retrospectively. Results The findings revealed that most of the patients were toddlers, 0–5 years (43%) Table 1.Length of stay and distribution of pneumonia patients in MMCPS Age Prevalence n(%) Male Patient ratioTime interval Adult N=232 Working daysper dayRange (year) 30%, followed by male gender (53%), with average length of stay from 1 to 7 days (79%). The most frequent comorbidity was anaemia (30%). The antibiotic utilized was predominantly injectables (85%) given as monotherapy 85% and under the class of cephalosporin category (66%). Ceftriaxone (59%).Conclusion: was the most commonly used antibiotic. The findings of this study reveal that the antibiotic prescription for pediatric and adolescent pneumonia patients at Bhayangkara Lemdiklat Polri Hospital are in line with previous research results, where ceftriaxone is the most commonly used as a single-agent injectable antibiotic.
HUBUNGAN TINGKAT PENGETAHUAN IBU TERHADAP PERILAKU SWAMEDIKASI DIARE PADA ANAK DI WILAYAH RW 002 KELURAHAN PETOGONGAN KECAMATAN KEBAYORAN BARU KOTA JAKARTA SELATAN Dewantoro, Agung; Ismaya, Nurwulan Adi; Nurlela, Nurlela; Susanti, Debi; Priono, Fransiskus Agus; Nurina, Sheima Sukmarina
PHRASE (Pharmaceutical Science) Journal Vol 6, No 1 (2026)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v6i1.1254

Abstract

ABSTRAKDiare adalah penyakit yang ditandai dengan pengeluaran tinja yang tidak normal berupa peningkatan volume, keenceran, serta frekuensi buang air besar lebih dari 3 kali sehari. Menurut WHO, diare merupakan penyakit yang menyebabkan kematian terbanyak pada anak. Swamedikasi adalah pengobatan sendiri semua penyakit yang tergolong ringan mulai dari gejala sampai dengan pemilihan obat-obatan. Tujuan penelitian ini untuk mengetahui ada atau tidaknya hubungan antara pengetahuan ibu mengenai diare pada anak dengan perilaku ibu terhadap swamedikasi diare pada anak di Wilayah RW 002 Kelurahan Petogogan Kecamatan Kebayoran Baru Kota Jakarta Selatan. Metode yang digunakan adalah metode deskriptif dengan teknik pengambilan sampel menggunakan total sampling. Hasil penelitian ini menunjukkan bahwa pengetahuan ibu mengenai diare pada anak dalam kategori baik sebanyak 119 responden (84,40%), pengetahuan ibu mengenai swamedikasi diare pada anak dalam kategori baik sebanyak 84 responden (59,57%), perilaku ibu mengenai swamedikasi diare pada anak dalam kategori cukup sebanyak 102 responden (72,34%). Kesimpulan dari penelitian ini menunjukkan bahwa tidak terdapat hubungan yang berarti pada tingkat pengetahuan ibu mengenai diare pada anak dan perilaku ibu terhadap swamedikasi diare pada anak dengan nilai uji spearman’s 0,123. Saran diharapkan ibu dapat meningkatkan perilaku swamedikasi diare dengan baik, sehingga ketika anak terkena diare dapat ditangani dengan tepat.