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All Journal Jurnal Biologi Tropis Acta Biochimica Indonesiana Cendana Medical Journal Jurnal Media Tropika: Jurnal Pengabdian Kepada Masyarakat
Rini, Desi Indria
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Relationship Between Physical Activity Intensity and Total Cholesterol Levels in Elderly at Social Welfare Service Unit (UPTD) for Elderly, Kupang Tenis, Linus Chaesarandy; Koamesah, Sanggwana Marthen Jacobus; Riwu, Audrey Gracelia; Rini, Desi Indria; Woda, Rahel Rara
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11077

Abstract

The increasing number of elderly individuals in Indonesia each year is accompanied by a higher prevalence of degenerative diseases, including hypercholesterolemia. However, with advancing age, elderly individuals tend to experience a decline in functional capacity, leading to reduced physical activity. This study aimed to analyze the relationship between physical activity intensity and total cholesterol levels among elderly residents at the Kupang Elderly Social Welfare Technical Implementation Unit (UPTD) in 2025. This analytical study employed a cross-sectional design involving elderly residents of the Kupang Elderly Social Welfare UPTD. Data were examined through both univariate and bivariate analyses employing the Chi-square test with a significance threshold of p < 0.05. A majority of the respondents fell into the young elderly category (60–69 years) and were mostly women. The findings revealed that the greater part of older participants showed low intensity in physical activity while having elevated total cholesterol levels. The Chi-square analysis demonstrated a meaningful connection between the intensity of physical activity and total cholesterol levels (p < 0.05). These findings suggest that a decrease in physical activity intensity correlates with an increase in total cholesterol levels among seniors. A noteworthy relationship exists between physical activity intensity and total cholesterol levels in elderly individuals at Kupang Elderly Social Welfare UPTD. Regular and appropriately tailored physical activity serves as an important strategy to maintain lipid metabolism balance and prevent cardiovascular disease risks in the elderly population.
Test of Antibacterial Activity of Star Fruit Leaf Ethanol Extract (Averrhoa bilimbi linn) Against the Growth of Propionibacterium acnes Mory, Ogy Rya; Rini, Desi Indria; Nurina, Rr. Listyawati; Manongga, Fidriati Olivia
Jurnal Biologi Tropis Vol. 25 No. 4a (2025): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4a.11135

Abstract

Treatment of Propionibacterium acnes infection can use antibiotics, but the use of antibiotics in the wrong dosage can trigger antibiotic resistance. The development of natural antibacterial research with herbal plant ingredients is one alternative to reduce the incidence of resistance. One of the plants used is star fruit leaf (Averrhoa bilimbi linn). This research aims to determine the antibacterial activity of ethanol extract of star fruit leaf (Averrhoa bilimbi linn) against the growth of Propionibacterium acnes. This research used a true experimental design research type with a post-test only control group design. This research used star fruit  leaf extract which is macerated using 70% ethanol solvent and evaporated until a thick extract is obtained. Testing of antibacterial activity using the disc diffusion method (Kirby-Bauer) against the bacteria Propionibacterium acnes. The analysis used is  the One Way Anova statistical test. Star fruit leaf extract contains alkaloid compounds, tannins, saponins, flavonoids, and steroids. The test results show that the average diameter of the inhibition zone formed by each sample was at a concentration of 100% of 17,07 mm, a concentration of 50% of 15,21 mm, a concentration of 25% of 14,16 mm, a concentration of 12,5% of 12,86 mm, a concentration of 6,25% of 12,08 mm, a concentration of 3,125% of 10,58 mm and a concentration of 1,56% of 9,16 mm. Star fruit leaf extract (Averrhoa bilimbi linn) has antibacterial activity against the growth  of Propionibacterium acnes.
Antibacterial Activity Test of Star Fruit Leaf Extract (Averrhoa bilimbi Linn) Against Staphylococcus epidermidis Elsen, Michellin; Rini, Desi Indria; Riwu, Magdarita; Wijaya, Carolin
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11238

Abstract

Staphylococcus epidermidis is a normal flora bacteria on the skin that can cause opportunistic infections. Generally, this infection is treated using antibiotics, but improper use of antibiotics can cause the onset of antibiotic resistance, so the development of natural antibacterial research with plant materials is one of the alternatives to reduce the incidence of resistance. A traditional medicinal plant is the leaves of star fruit (Averrhoa bilimbi Linn). This research aimed to investigate the antibacterial properties of the extract from star fruit leaves on Staphylococcus epidermidis. The type of research used is a true experimental design with a post-test only control group design. The treatment group in this study consisted of concentrations of 100%, 50%, 25%, 12.5%, 6.25%, 3.12%, with a positive control of clindamycin at a dose of 2 μg and a negative control of sterile aquadest which was carried out 3 times for each test group. The antibacterial test method is carried out by the disc diffusion method. The data analysis used is the One Way Anova statistical test. Star fruit leaf extract contains alkaloid compounds, tannins, saponins, flavonoids, and steroids. There is antibacterial activity of star fruit leaf extract against Staphylococcus epidermidis. The inhibition zone was produced at various concentrations of 100% (⌀ 15.14 mm), 50% (⌀ 14.06 mm), 25% (⌀ 13.75 mm), 12.5% (⌀ 12.01 mm), 6.25% (⌀ 10.55 mm), and 3.12% (⌀ 9.03 mm). Starfruit leaf extract has antibacterial activity against Staphylococcus epidermidis.
Testing The Laxative Activity of Utasupe Leaf Juice from The Ende Region on White Rats (Rattus novergicus) Loperamid Induced Constipation Model Hendrik, Einstein Daud Victor; Nurina, Rr. Listyawati; Manafe, Derri Tallo; Rini, Desi Indria; Dean, Muhajirin
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11608

Abstract

Constipation is a problem in the pattern of elimination due to the presence of dry or hard feces passing through the large intestine, while a laxative is a substance that can provide stimulation of intestinal peristalsis as a reflex of direct stimulation of the intestinal wall that can facilitate defecation. Many medicinal plants can treat constipation, one of which is Utasupe. Utasupe is a vegetable plant originating from the Ende region. In Ende, Utasupe is believed to facilitate bowel movements, so people often consume Utasupe. This study aims to determine the laxative effect of Utasupe leaf juice from Ende region on loperamide-induced male white rats (Rattus novergicus). The study was conducted experimentally on 30 Sprague daley strain white rats aged 8-12 weeks. The parameter for testing the laxative effect was the defecation pattern, while the observed parameter was the frequency of defecation every hour for 8 hours. Utasupe leaf juice was administered orally at a dose of 125 mg/mL, 250 mg/mL and 500 mg/mL, as a comparison negative control (Na-CMC) and positive control (Bisacodyl) were used. The results showed that the administration of Utasupe leaf juice at a dose of 250 mg/mL had a laxative effect on male white rats. Utasupe leaf juice has laxative activity in white rats (Rattus novergicus). The time required for defecation to occur after being given Utasupe leaf juice from the Ende area in white rats (Rattus novergicus) is one hour with the most effective dose is 250 mg/mL.
Antibacterial Activity of Ethanol Extract of Red Betel Leaves (Piper crocatum) Against Propionibacterium acnes Sihombing, Angelina Victoria; Rini, Desi Indria; Woda, Rahel Rara; Amat, Anita Lidesna Shinta
Jurnal Biologi Tropis Vol. 26 No. 1 (2026): Januari-Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v26i1.11714

Abstract

Propionibacterium acnes is a type of bacteria that typically exists on skin areas with many sebaceous glands, like the scalp and face. The exploration of natural antibacterial agents made from herbal plants is one approach to decrease resistance issues. One such plant utilized is red betel, scientifically known as Piper crocatum. The objective of this study is to assess the antibacterial properties of the ethanol extract from red betel leaves against Propionibacterium acnes. This study adopted a true experimental framework with a post-test only control group model. The red betel leaf extract was produced through maceration using a 70% ethanol solution, followed by evaporation until a concentrated extract was achieved. In this study, the treated groups included various concentrations: 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, and 1.56%, alongside a positive control using clindamycin and a negative control using sterile aquades. The antibacterial testing was performed using the disc diffusion method, referred to as the Kirby-Bauer technique against Propionibacterium acnes bacteria. The analysis conducted was the One Way Anova statistical test. Findings from this study reveal that the extract of red betel leaves contains alkaloids, tannins, saponins, flavonoids, and terpenoids. The testing outcomes indicate that the average diameter of the inhibition zone resultant from each sample is 11.16 mm for the 100% concentration, 9.63 mm for the 50% concentration, 8.85 mm for the 25% concentration, 8.21 mm for the 12.5% concentration, 7.78 mm for the 6.25% concentration, 6.93 mm for the 3.125% concentration, and 0 mm for the 1.56% concentration. From the results, it can be concluded that the ethanol extract from red betel leaves exhibits antibacterial activity against the growth of Propionibacterium acnes.
Co-Authors Anita Lidesna Shinta Amat Artawan, I Made Audrey Gracelia Riwu Bandi, Richard Gilbert Christina Olly Lada Deri Riskiyanti Tallo Manafe Djawa, Mariethan Sisilia Alfiola Djunaidi, Savitry R. Maudy Elsen, Michellin Folamauk, Conrad Liab Hendricson Hendrik, Einstein Daud Victor Idawati Trisno Jumba, Cynthia Benedikta Kabosu, Agustin M. Vianelde L. Koamesah, Sanggwana Marthen Jacobus Kresnawati Wahyu Setiono Lidia, Kartini Lomu Nifu, Florya Jocenly Manongga, Fidriati Olivia Maria Agnes Etty Dedy Mauti, Imelda Maria Mory, Ogy Rya Nurina, Rr. Listyawati PAKAN, PRISCA DEVIANI Ratu Edo, Megaputri Yoriska Ratu, Kristian Riwu, Magdarita Sagita, Sidarta Sengi, Tekla Windyanita Setianingrum, Elisabeth Levina Sari Sihombing, Angelina Victoria Syahrir Syahrir Tenis, Linus Chaesarandy To Rante, Su Djie Wijaya, Carolin Woda, Rahel Rara