Article Per Year (5 Year)
p-Index From 2021 - 2026
2.319
P-Index
This Author published in this journals
All Journal Medical Journal of Indonesia Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Indonesian Journal of Cancer Neurona Acta Neurologica Indonesia
Aninditha, Tiara
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 13 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 13 Documents
Search

 1   2 
Management High Grade Glioma in Elderly Sofyan, Henry Riyanto; Pratiwi, Intan; Fahmi Radityamurti; Anastasia Asylia Dinakrisma; Aninditha, Tiara; Savitri, Irma
Acta Neurologica Indonesia Vol. 3 No. 03 (2025): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v3i03.93

Abstract

Introduction: High-grade glioma (HGG) is an aggressive primary brain tumor with poor prognosis, particularly in elderly patients. Management is complex due to comorbidities, decreased functional status, and increased risk of treatment-related toxicity. Personalized approaches balancing efficacy and quality of life are essential in this population. Case Report: A 67-year-old male presented with progressive headache, limb weakness, and visual disturbances. MRI revealed a large right temporoparietal lesion suggestive of HGG. Craniotomy and biopsy confirmed a high-grade glioma. The patient had a Karnofsky Performance Status (KPS) of 40, with significant cognitive and functional impairments, along with comorbidities including diabetes and hypertension. Given his frailty, he was treated with hypofractionated radiotherapy and concurrent temozolomide. Discussion: Treatment decisions in elderly HGG patients should consider age, KPS, cognitive status, and comorbidities. Hypofractionated radiotherapy combined with temozolomide is effective and better tolerated in frail patients. Multidisciplinary care is crucial to manage physical, cognitive, and emotional needs. Cognitive assessment before therapy aids in anticipating treatment impact. Prophylactic treatment for opportunistic infections such as Pneumocystis jirovecii is recommended during chemotherapy. Conclusion: Elderly patients with HGG require individualized, multidisciplinary care. Factors such as performance status, cognitive function, and comorbidities must guide treatment to achieve optimal outcomes while preserving quality of life
Rare Case of Solitary Brain Metastasis from Colorectal Cancer Ririhena, Fiorentina C; Aninditha, Tiara; Sofyan, Henry Riyanto; Madjid, Irma Savitri
Acta Neurologica Indonesia Vol. 4 No. 02 (2026): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v4i02.94

Abstract

Introduction: Solitary brain metastasis (BM) from colorectal cancer (CRC) is rare (0.6–3.2%) and presents management challenges, especially in eloquent brain regions where surgical resection carries high risk. Stereotactic radiotherapy (SRT) is often preferred when surgery is not feasible, particularly in patients with good functional status. Case Illustration: A 49-year-old male with a KPS of 90 presented with worsening right-sided pulsating headaches for five days, accompanied by left-sided facial nerve palsy. MRI revealed a solitary intra-axial metastasis in the right temporal lobe, an eloquent region, with microbleeds and surrounding edema, suggestive of BM from rectal adenocarcinoma. Given the lesion's eloquent location, where surgery posed high risks, SRT was selected as the primary treatment modality, alongside corticosteroids for edema control and psychiatric support for depression Discussion: Solitary CRC BM in eloquent regions is a clinical dilemma. While surgery is standard for accessible lesions, SRT offers effective tumor control while reducing neurological complications, making it preferable for patients with high KPS (≥90) as it preserves cognitive function and improves survival outcomes. A multidisciplinary and holistic treatment approach, addressing both oncological and psychological aspects, is essential. Conclusion: Managing solitary CRC BM in eloquent brain regions requires special strategies. SRT was favored to reduce the risk of neurological impairment while maintaining tumor control, especially when surgery was not viable. A multidisciplinary approach is crucial to optimizing care and improving quality of life. Keywords: solitary brain metastasis, colorectal cancer, stereotactic radiotherapy, eloquent brain region
Distinguishing Spinal Cancer and Degenerative Disease: Enhancing Diagnosis and Treatment Outcomes in Plasmacytoma -, Liana Alviah Saputri; Riyanto Sofyan, Henry; Aninditha, Tiara; Savitri, Irma; Saekhu, Mohammad; Kusuma, Radius
Acta Neurologica Indonesia Vol. 4 No. 01 (2026): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Spinal lesions commonly exhibit overlapping clinical presentations and imaging characteristics, which can obscure the distinction between malignant and degenerative etiologies. This diagnostic ambiguity may lead to delayed or inappropriate treatment, particularly in uncommon neoplastic entities such as plasmacytoma, a solitary manifestation of plasma cell dyscrasia that often involves the spine. Case Report: We report the case of a 63-year-old male presenting with one month of persistent back pain, progressive bilateral lower limb weakness, and tingling sensations radiating from the inguinal region to the toes. Imaging studies revealed bilateral pedicle destruction at the L2 and L5 vertebrae, along with significant spinal canal and foraminal stenosis. The patient underwent decompression surgery, and histopathological analysis of the lesion confirmed the diagnosis of plasmacytoma. Discussion: Spinal plasmacytoma is a rare neoplastic condition that can clinically mimic degenerative spine disorders, often leading to delays in diagnosis and treatment. Symptoms such as chronic back pain, radiculopathy, and motor weakness are commonly attributed to more prevalent degenerative pathologies, particularly in older adults. Back pain in individuals with a history of malignancy serves as a crucial warning sign, prompting clinicians to urgently assess for potential metastatic disease in the spine. Conclusion: Increased awareness and a high index of suspicion are crucial when evaluating spinal lesions. Pain should be considered a key red flag warranting prompt assessment for possible spinal malignancy. Early diagnosis is critical, as it directly affects therapeutic decisions and overall prognosis.
Co-Authors -, Liana Alviah Saputri Agiananda, Feranindhya Ahmad Yanuar Albertin, Elizabeth Alvonsius Silalahi, Raymond Aris Nimrod Alvonsius, Raymond Aris Nimrod Anastasia Asylia Dinakrisma Andayani, Diyah Eka Andhika Rachman Aria Kekalih Ariarini, Ni Nengah Rida Diafiri, Dinda Djohansjah, Joice Rosewitasari Aryanti Fahmi Radityamurti Faiq, Ahmad Rafi Hakim, Manfaluthy Hartono, Chandra Hervita Diatri Humaira, Sarah Imran, Darma Indrapriambada, Ery Riady IRWANTO Karnasih, Artasya Kusuma, Radius Kusumaningrum, Profitasari Madjid, Irma Savitri Maulina, Lisa Natadisastra, Raden Muharram Nugraeni, Tiara Nurmiati Amir Pratiwi, Intan Prayangga, Regina Pukovisa Prawiroharjo, Pukovisa Puspaseruni, Putri Air Putri Auliya, Putri Rahmad Mulyadi Ranakusuma, Teguh Ranakusuma, Teguh A. S Renindra Ananda Aman Rini Andriani Ririhena, Fiorentina C Riwanti Estiasari Riyanto Sofyan, Henry Saekhu, Mohammad Samjunanto, Achmad Sari, Riska Nanda Savitri, Irma Sembiring, Saulina Sinthia, Novita Ayu Sitorus, Freddy Sofyan, Henry Riyanto Susanto, Eka Tanjung, Gloria Tejomukti, Teddy Velyani, Dyani Pitra Wahmurti, Tuti Wibisono, Sasanto Winnugroho Wiratman Yesnuar Safri, Ahmad Zairinal , Ramdinal Aviesena