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All Journal Prosiding Seminar Nasional Sains Dan Teknologi Fakultas Teknik Adi Widya : Jurnal Pengabdian Masyarakat Journal of Dedicators Community JPSCR : Journal of Pharmaceutical Science and Clinical Research PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Farmasi Indonesia Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Biomedika Abdimas UNWAHAS : Jurnal Pengabdian Masyarakat UNWAHAS Jurnal Farmasi Jurnal Pengabdian kepada Masyarakat EduNaturalia: Jurnal Biologi dan Kependidikan Biologi Parapemikir Jurnal Ilmiah Farmasi
Siti Aisiyah
Program Studi S1 Farmasi, Universitas Setia Budi, Surakarta
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Determination of SPF value in Serum Preparation of Ethyl acetat fraction ethanol extract of Roselle Petals (Hibiscus sabdarifa L.) Vivin Nopiyanti; Reslely Harjanti; Siti Aisiyah
Jurnal Farmasi (Journal of Pharmacy) Vol 11, No 1 (2022)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v11i1.163

Abstract

The ethyl acetate fraction of the ethanol extract of roselle flower petals (Hibiscus sabdariffa L.) was reported to have an SPF value of 13.83 ± 1.50 which was higher than the ethanol extract. So with the SPF value, the ethyl acetate fraction of roselle flower ethanol extract can be used as a sunscreen. One of the cosmetic preparations that is currently growing rapidly is serum. The purpose of this study was to formulate the ethyl acetate fraction of roselle petals into a serum that had good physical quality with variations in the concentration of xanthan gum and then the SPF value was determined. This research begins with the manufacture of ethanol extract of roselle petals. Then fractionation (liquid-liquid partition) was carried out using solvents with different polarities, namely n-hexane and ethyl acetate. Furthermore, the ethyl acetate fraction was formulated into serum with variations in the concentration of xanthan gum 0.3%, respectively; 0.6% and 1.2% were then tested for physical quality and stability. The next step is to determine the SPF value of the serum by using the UV spectrophotometric method and its calculation using the Mansur equation. The results showed that the serum ethyl acetate fraction of the ethanolic extract of roselle petals could be made into gel preparations with good physical qualities including organoleptic, viscosity, pH and homogeneity. Serum ethyl acetate fraction ethanol extract of roselle flower formulas 1, 2 and 3 had SPF values F1 respectively, namely 6.8595 ± 0.08 which included moderate protection potential; F2 is 7.0089 ± 0.17; and F3 which is 8.2251 ± 0.32 with extra protection potential. Variations in the concentration of xanthan gum in the serum formula affect the physical quality of the viscosity and potency of sunscreen preparations..
Pengaruh Konsentrasi Asam Stearat Terhadap Mutu Fisik Losion Ekstrak Daun Nangka (Arthocarpus heterophyllus) Sebagai Antioksidan Natasya Sava Agasta; Siti Aisiyah; Mamik Ponco Rahayu
Jurnal Farmasi (Journal of Pharmacy) Vol 11, No 1 (2022)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v11i1.173

Abstract

Jackfruit leaf extract was developed into a lotion preparation to increase skin moisture and prevent the skin from being exposed to free radicals.  The purpose of this study was to determine the effect of variations in stearic acid base on physical quality, differences in antioxidant activity in jackfruit leaf extract and preparations, best formula that can provide antioxidant activity.Jackfruit leaf extract was obtained by maceration using 70% ethanol and then formulated with a concentration of 6% jackfruit leaf extract and variations in stearic acid base 2%, 3%, and 4%. This study used the DPPH method to determine antioxidant activity and ANOVA for statistical analysis.  This study obtained the IC50 value of jackfruit leaf extract of 64.5616 ppm. Variations of stearic acid have an effect on the physical quality and value of antioxidant activity. The IC50 value of jackfruit leaf extract and lotion was different due to the presence of additional ingredients in the lotion.  The best formula from this research, formula has the best physical quality value, with the IC50 value of the extract in the formula 70.6862 ppm and the IC50 value of the base in the formula 1179.3357 ppm. 
PEMANFAATAN BUNGA ROSELLA (HIBISCUS SABDARIFFA L.) SEBAGAI BAHAN ALAMI UNTUK UPAYA PREVENTIF DAN PROMOTIF KESEHATAN BAGI MASYARAKAT NUSUKAN BANJARSARI SURAKARTA Siti Aisiyah; Reslely Harjanti; Vivin Nopiyanti
ABDIMAS UNWAHAS Vol 2, No 1 (2017)
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/abd.v2i1.1786

Abstract

Paparan radikal bebas yang berasal dari polusi udara yang kita hirup, polutan yang langsung kontak dengan kulit kita maupun makanan dan minuman yang kita konsumsi dapat memicu timbulnya berbagai jenis penyakit. Berbagai cara dilakukan untuk pengobatan jika kita sudah terlanjur sakit dan biaya yang dikeluarkan juga mahal. Oleh karena itu perlu diupayakan tindakan pencegahan (preventif) dan peningkatan derajat kesehatan (promotif) supaya terhindar dari berbagai penyakit tersebut dengan biaya yang jauh lebih terjangkau. Penggunaan antioksidan alami sebagai upaya tindakan preventif dan promotif kesehatan dinilai sebagai tindakan yanglebih baik karena bahan kimia berpotensi menimbulkan efek yang berbahaya.Tujuan dari program kegiatan pengabdian masyarakat ini adalah memberikan pengetahuan sekaligus pelatihan ketrampilan masyarakat khususnya wilayah Praon Nusukan Banjarsari Surakarta tentang pemanfaatan bunga rosella sebagai bahan pangan dan bahan tambahan pangan (BTP) alami serta sediaan kosmetik yang mudah pembuatannya, murah harganya serta berkhasiat untuk kesehatan.Kata kunci: Bunga Rosella, Krim, Bahan Tambahan Pangan, Antioksidan
Pelatihan Pembuatan Sabun Cuci Tangan Penunjang PHBS bagi Kader PKK Wilayah Kadipiro Banjarsari Surakarta Reslely Harjanti; Vivin Nopiyanti; Siti Aisiyah; Yari Mukti Wibowo; Gregorius Prima Indra Budianto
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 1 No. 9: Februari 2022
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v1i9.1281

Abstract

Tidak semua anggota masyarakat paham pentingnya Perilaku Hidup Bersih dan Sehat (PHBS) contohnya cuci tangan sebagai salah satu upaya dalam pencegahan penularan virus corona. Kegiatan pengabdian masyarakat ini bertujuan untuk mendukung program pemerintah dalam pencegahan penularan/ penyebaran virus corona dengan memberikan edukasi serta diseminasi pembuatan sabun cuci tangan kepada kader PKK di lingkungan Sukomulyo Kadipiro Banjarsari Surakarta. Kegiatan pengabdian dimulai dari perijinan kepada ketua RT dan Lurah Kadipiro. Selanjutnya dilakukan pretest untuk mengetahui tingkat pengetahuan peserta terkait PHBS serta pembuatan sabun cuci tangan. Selanjutnya dilakukan pelatihan pembuatan sabun cuci tangan. Tahapan akhir adalah evaluasi postest melalui kuesioner yang dibagikan kepada peserta dan hasilnya dibandingkan dengan hasil pretest dan diuji statistik. Hasil kegiatan berupa produk sabun cuci tangan dikemas dalam wadah yang menarik dapat dikembangkan untuk usaha mandiri warga. Hasil uji statistik menunjukkan bahwa peserta pelatihan memahami proses pembuatan sabun cuci tangan ditandai ada perbedaan signifikan (alfa<0.05) pada uji statistik.
OPTIMASI SEDIAAN GUMMY CANDY PARASETAMOL DENGAN VARIASI KONSENTRASI GELATIN DAN GLISERIN MENGGUNAKAN METODE SIMPLEX LATTICE DESIGN Siti Aisiyah
Jurnal Farmasi (Journal of Pharmacy) Vol 11, No 2 (2022)
Publisher : SEKOLAH TINGGI ILMU KESEHATAN NASIONAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37013/jf.v11i2.211

Abstract

Gummy candy parasetamol adalah permen kenyal yang tersusun atas campuran pemanis dan komponen hidrokoloid yang mengandung parasetamol dan didesain untuk hancur dan lumer di lidah. Penelitian ini bertujuan untuk melihat pengaruh variasi konsentrasi gelatin dan gliserin terhadap kualitas fisik sediaan parasetamol gummy candy, serta mengetahui konsentrasi gelatin dan gliserin yang terbaik untuk mendapatkan sediaan parasetamol gummy candy dengan sifat fisi k optimum.Pembuatan sediaan menggunakan metode cetak tuang dan menggunakan 8 rancangan formula dari Design Expert Simplex Lattice Design dengan perbandingan konsentrasi gelatin dan gliserin. Hasil uji mutu fisik dengan parameter kritis kekenyalan dan kadar air, dianalisis dengan metode Simplex Lattice Design. Metode ini dapat digunakan untuk optimasi formula sediaan pada berbagai variasi jumlah komposisi bahan, sehingga menghasilkan formula optimum dengan karakteristik fisik yang diharapkan.Hasil penelitian menunjukkan bahwa gelatin lebih berpengaruh pada kekenyalan dan gliserin lebih berpengaruh pada kadar air gummy candy parasetamol. Proporsi gelatin 998,723 mg dan gliserin 51,277 mg menghasilkan formula optimum dengan kekenyalan dan kadar air gummy candy parasetamol terbaik.  
PELATIHAN PEMBUATAN SEDIAAN PERMEN SIRSAT SEBAGAI ANTIOKSIDAN SEBAGAI DAYA TAHAN TUBUH DI WILAYAH KERTEN LAWEYAN SURAKARTA: PELATIHAN PEMBUATAN SEDIAAN PERMEN SIRSAT SEBAGAI ANTIOKSIDAN SEBAGAI DAYA TAHAN TUBUH DI WILAYAH KERTEN LAWEYAN SURAKARTA Vivin Nopiyanti; Reslely Harjanti; Siti Aisiyah; Titik Sunarni; Suhartinah Suhartinah; Ilham Kuncahyo
Adi Widya : Jurnal Pengabdian Masyarakat Vol. 6 No. 2 (2022): Adi Widya: Jurnal Pengabdian Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33061/awpm.v6i2.6889

Abstract

Soursop fruit contains vitamin C and polyphenolic compounds that have the potential as a source of antioxidants. It is hoped that by consuming a lot of soursop fruit it will provide an increase in memory and to maintain cell damage due to free radicals. Making soursop candy preparations will allow use which is relatively easy to use and gives a good taste so that not only adults consume it but also for children. Service activities are divided into several stages starting from surveys and observations, followed by training in the form of tutorials then mentoring from the service team and ending with activity evaluation. Making soursop candy preparations is easy, simple and uses simple tools. We often encounter soursop fruit in the yard and for additional materials for making soursop preparations, it is easy to find on the market and the price is cheap. The principle of making it is all the ingredients are boiled until it becomes a semi-solid dough. Then wait until it cools down. Once cool, cut according to taste and wrapped in an attractive wrapper. Service activities carried out in RT 1/RW 1, Laweyan District, Surakarta went well while still implementing health protocols. In addition to providing training on making soursop candy preparations for PKK cadres in Kerten Laweyan Surakarta, training was also held related to opportunities to be developed as community independent businesses. The conclusion of the activity and evaluation of the preparation of soursop candy is considered to have the potential to be developed so that it can be used as an independent business product that is marketed commercially.
Formulasi Sabun Mandi Padat Ekstrak Daun Jeruk Bali (Citrus Maxima Merr.) sebagai Antibakteri terhadap Staphyloccous aureus Noela Riski Riani Sumbung; Vivin Nopiyanti; Siti Aisiyah; Reslely Harjanti
Journal Syifa Sciences and Clinical Research Vol 5, No 1 (2023): Volume 5 Edisi 1 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i1.16874

Abstract

Solid bath soap is one of the most common cosmetic preparations used by the public to clean the body from dirt. Grapefruit leaves contain flavonoids that are able to maintain healthy skin, and can inhibit the growth of bacteria. The purpose of this study was to formulate the leaf extract of grapefruit into a solid bath soap that has good physical and stability qualities and to determine its antibacterial effect against S. aureus. Grapefruit leaves were macerated with 96% ethanol solvent then the extract obtained was formulated into solid soap preparations with extract variations, namely 1; 3 and 5%. Furthermore, physical quality and stability tests have been carried out as well as testing the antibacterial activity of the bath soap preparations against S. aureus bacteria by agar diffusion method by means of wells. The final stage was statistical data analysis. The results showed that the solid bath soap preparations with grapefruit leaf extract had good physical quality and stability, the formulation of solid bath preparations with extract concentrations of 1%, 3%, and 5% had antibacterial activity with an average diameter of the inhibition zone against S. aureus bacteria were 5.6 mm, 7 mm and 10.8 mm, respectively, which were included in the moderate to strong category. The formulation with the addition of 5% extract had the most effective antibacterial activity with an average inhibition zone of 10.8 mm.
FORMULASI SEDIAAN KRIM ANTIOKSIDAN EKSTRAK METANOL KULIT BUAH PISANG RAJA (Musa paradisiaca L.) Dwi Ayunda Putri; Endang Sri Rejeki; Siti Aisiyah
EduNaturalia: Jurnal Biologi dan Kependidikan Biologi Vol 4, No 1 (2023)
Publisher : FKIP Universitas Tanjungpura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/edunaturalia.v4i1.61455

Abstract

Antioxidant compounds are compounds that counteract or reduce the negative impact of oxidants, which work by donating one electron charge so that the activity of these oxidant compounds can be prevented or inhibited. The aim of this study was to determine the formula for cream variation of extract from banana peel which has the best antioxidant activity with good quality and stability of the preparation. In this study, the antioxidant cream used 3 (three) series of concentrations of the methanol extract of the skin of the plantain (Musa paradisiaca L.) fruit, namely 0.5%, 1% and 2%. The methanol extract of plantain peel was obtained by maceration method with methanol as solvent. Antioxidant cream was tested for physical quality and stability which included organoleptic test, viscosity test, pH test, homogeneity test, adhesion test, and spreadability test. The antioxidant power test was carried out using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) method using a UV-Vis spectrophotometer with a wavelength of 400-600 nm. The results of the study were further analyzed statistically using the Tukey method and one-way ANOVA. The results showed that the methanol extract of plantain peel had very strong antioxidant activity, and cream preparations could be made with various extract concentrations and the IC50 values of formula 1, formula 2 and formula 3 were 53.81 ppm, 53.29 ppm and 53.21 ppm.
Pengaruh Proporsi Lipid Cair Dan Surfaktan Terhadap Aktivitas Antioksidan Pada NLC Resveratrol Padusitrada Padusitrada; Siti Aisiyah; Reslely Harjanti
Parapemikir : Jurnal Ilmiah Farmasi Vol 12, No 1 (2023): Parapemikir : Jurnal Ilmiah Farmasi
Publisher : Pusat Penelitian dan Pengabdian Masyarakat Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/pjif.v12i1.4323

Abstract

Resveratrol adalah bahan alam yang dilaporkan mempunyai potensi antioksidan melalui pengujian in vitro metode DPPH•, ABTS•+, DMPD•+, total aktivitas antioksidan, kemampuan pereduksi serta aktivitas pengkhelat terhadap Fe2+. Resveratrol mempunyai kelarutan yang rendah dalam air yang akan berpengaruh pada bioavailabilitasnya. Sehingga dibuat sistem NLC sebagai sistem pembawa yang sesuai untuk meningkatkan kelarutan resveratrol. Penelitian ini bertujuan untuk mengetahui pengaruh variasi proporsi lipid cair dan surfaktan terhadap efisiensi penjerapan, pelepasan obat, dan aktivitas antioksidan serta menentukan formula NLC resveratrol dengan efek paling baik terhadap ketiga faktor tersebut. Pembuatan sistem NLC menggunakan variasi proporsi lipid cair dan surfaktan dengan metode emulsifikasi yang kemudian dilanjutkan dengan sonikasi. Formula NLC resveratrol yang dibuat dilakukan pengujian meliputi uji penjerapan, uji pelepasan obat, dan uji aktivitas antioksidan. Hasil pengujian penjerapan, formula 4 dengan konsentrasi lipid cair dan surfaktan paling tinggi menunjukkan penjerapan paling tinggi. Hasil pada uji pelepasan obat, formula 2 dengan konsentrasi lipid cair tinggi sedangkan surfaktan rendah menunjukkan pelepasan paling tinggi. Hasil aktivitas antioksidan tidak terpengaruh terhadap perbedaan variasi konsentrasi lipid cair (asam oleat) maupun surfaktan (tween 80).
PELATIHAN PEMBUATAN AROMATERAPI ROLL ON PADA KELOMPOK DHARMA WANITA SMAN 1 WONOSARI KLATEN Titik Sunarni; Suhartinah, Suhartinah; Ilham Kuncahyo; Harjanti, Reslely; Siti Aisiyah; Vivin Nopiyanti
J-ABDI: Jurnal Pengabdian kepada Masyarakat Vol. 4 No. 2: Juli 2024
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53625/jabdi.v4i2.8009

Abstract

Sediaan aromaterapi roll on menjadi salah satu pilihan pada saat kita mengalami gangguan kesehatan misalnya rasa mual dan tidak enak badan karena masuk angin atau rasa pegal karena lelah setelah beraktivitas. Kegiatan ini bertujuan untuk memberikan informasi, pengetahuan dan keterampilan terkait sediaan aromaterapi bentuk roll on serta wacana untuk meningkatkan jiwa kewirausahaan peserta. Kegiatan pengabdian dilakukan dengan metode ceramah, diskusi dan praktek secara langsung tentang pembuatan sediaan roll on aromaterapi. Peserta kegiatan adalah kelompok Dharma Wanita SMAN 1 Wonosari Klaten. Selesai kegiatan dilakukan evaluasi terhadap kegiatan yang sudah dilakukan. Peserta kegiatan pengabdian sangat antusias selama pelaksanaan kegiatan ditunjukkan dengan hasil evaluasi dan diskusi bersama yang sudah dilakukan. Kegiatan dinilai bermanfaat untuk menambah pengetahuan dan kemampuan dalam pembuatan sediaan roll on aromaterapi serta meningkatkan jiwa kewirausahaan peserta.
Co-Authors Dwi Ayunda Putri ELISABETH APRILIA Gregorius Prima Indra Budianto, Gregorius Prima Indra Husnul Khatimah Ilham Kuncahyo, Ilham Mamik Ponco Rahayu Mimiek Murrukmihadi Muhammad Dzakwan Natasya Sava Agasta Noela Riski Riani Sumbung Padusitrada Padusitrada Pudiastuti R.S.P Rani Dewi Pratiwi Reslely Harjanti Rika Widyapranata Suhartinah Suhartinah Suhartinah Suhartinah, Suhartinah Syamsul Arifin Titik Sunarni Valentina Ayuk Armadani Vivin Nopiyanti Wulandari, Destik Yari Mukti Wibowo Yunita Ayuningtyas Â