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Amalia, Annora Rizky
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Kelayakan Ekstrak Daun Pandan (Pandanus amaryllifolius) Sebagai Formulasi Sediaan Masker Gel Peel Off Riyan Setiyanto; Annora Rizky Amalia; Ela Fransisca Christa S
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 3 (2024): Juli-September 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15323

Abstract

Pandanus amaryllifolius leaves have antioxidant activity. The use of antioxidant effects for facial skin is better in topical cosmetic formulations than oral preparations. Peel-off masks are generally used to moisturize the skin. This study aimed to formulate and test the physical quality of the peel-off gel mask preparation of Pandanus amaryllifolius leaves with variations in extract concentration and polyvinyl alcohol. From the formulation and physical property tests, it can be seen how variations in polyvinyl alcohol concentration affect the physical properties of the peel-off gel mask preparation. This study was included in experimental analytical research. The variables measured from the peel-off gel mask preparation of Pandanus amaryllifolius leaves were adhesive power, spreadability, drying time, pH and viscosity. Differences in variables between concentrations were analyzed by the Anova test for numerical variables and the Kruskal Wallis test for ordinal categorical variables. Based on the results of the organoleptic test, all formulations showed a thick consistency, green color and a distinctive pandan leaf odor. According to the results of the comparative test, it was found that the variation of the concentration of extract and polyvinyl alcohol significantly affected the adhesive power, spread power and drying time, but did not significantly affect the pH and viscosity. The results of the irritation test on the three formulations showed that the preparation did not irritate so that the formulation was safe to use. Furthermore, it was concluded that pandan leaf extract can be used as a formulation for a peel-off gel mask preparation and is safe because it does not irritate the skin.Keywords: Pandanus amaryllifolius; peel-off mask; polyvinyl alcohol ABSTRAK Daun Pandanus amaryllifolius mempunyai aktivitas antioksidan. Penggunaan efek antioksidan untuk kulit wajah, lebih baik dalam formulasi kosmetika sediaan topikal daripada sediaan oral. Masker peel off umumnya digunakan untuk melembabkan kulit. Penelitian ini bertujuan memformulasikan dan menguji kualitas fisik dari sediaan masker gel peel off daun Pandanus amaryllifolius dengan variasi konsentrasi ekstrak dan polyvinyl alcohol. Dari formulasi dan uji sifat fisik tersebut dapat diketahui bagaimana variasi konsentrasi polyvinyl alcohol mempengaruhi sifat fisik sediaan maker gel peel off. Penelitian ini termasuk dalam penelitian analitik eksperimental. Variabel yang diukur dari sediaan masker gel peel off daun Pandanus amaryllifolius ini adalah daya lekat, daya sebar, waktu mengering, pH dan viskositas. Perbedaan variabel antar konsentrasi dianalisis  dengan uji Anova untuk variabel numerik dan uji Kruskal Wallis untuk variabel kategorik ordinal. Berdasarkan hasil uji organoleptik semua formulasi menunjukkan konsistensi sediaan yang kental, berwarna hijau dan berbau khas daun pandan. Menurut hasil uji perbandingan, diperoleh hasil bahwa variasi konsentrasi ekstrak dan polyvinyl alcohol berpengaruh secara signifikan terhadap daya lekat, daya sebar dan waktu mengering, tetapi tidak berpengaruh secara signifikan terhadap pH dan viskositas. Hasil uji iritasi terhadap ketiga formulasi diperoleh bahwa sediaan tidak mengiritasi sehingga formulasi tersebut aman untuk digunakan. Selanjutnya disimpulkan bahwa ekstrak daun pandan dapat digunakan sebagai formulasi sediaan masker gel peel off dan aman karena tidak mengiritasi kulit.Kata kunci: Pandanus amaryllifolius; masker peel off; polyvinyl alcohol
Kombinasi Ekstrak Buah Takokak dan Kulit Pisang Kepok Sebagai Penghambat Pertumbuhan Bakteri Propionibacterium acnes Annora Rizky Amalia; Diyan Sakti Purwanto; Natasya Maya Isabella
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 4 (2024): Oktober-Desember 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15441

Abstract

Takokak (Solanum torvum swartz) is a plant that has antibacterial activity. Antibacterial activity is also found in yellow banana peel waste (Musa balibisiana). The purpose of this study was to determine the antibacterial activity of a combination of takokak fruit extract and yellow banana peel waste against Propionibacterium acnes. This study was conducted using the disk diffusion method and is an experimental study. Ethanol extract of yellow banana peel waste and takokak fruit was made by the maceration method with 70% ethanol solvent. Antibacterial tests were carried out using disc paper with variations in extract concentration, namely 15%, 20%, and 25% dissolved in distilled water. The positive control used was clindamycin, while the negative control was distilled water. The parameters measured were the inhibition zone, which is the clear area around the disc where there is no bacterial growth, measured in millimeters. The results of the antibacterial test of the combination of takokak fruit and kepok banana peel waste in a ratio of 2:1 had the highest inhibitory power at concentrations of 15%, 20% and 25%, respectively, which were 16.03 mm, 17.10 mm and 18.63 mm. The positive control produced an inhibitory power of 35.45 mm while the negative control had no inhibitory power. Furthermore, it was concluded that the combination of takokak fruit extract and kepok banana peel is effective in inhibiting the growth of Propionibacterium acnes bacteria.Keywords: Solanum torvum swartz; Musa balbisiana; 70% ethanol extract; maceration; Propionibacterium acnes ABSTRAK Takokak (Solanum torvum swartz) merupakan tanaman yang memiliki aktivitas anti bakteri. Aktivitas antibakteri juga ditemukan pada limbah kulit pisang kepok kuning (Musa balibisiana). Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri kombinasi ekstrak buah takokak dan limbah kulit pisang kepok kuning terhadap Propionibacterium acnes. Penelitian ini dilakukan dengan metode disk diffusion dan merupakan studi eksperimental. Ekstrak etanol limbah kulit pisang kapok kuning dan buah takokak dibuat dengan metode maserasi dengan pelarut etanol 70%. Uji antibakteri dilakukan dengan menggunakan kertas cakram dengan variasi konsentrasi ekstrak yaitu 15%, 20%, dan 25% yang dilarutkan dalam aquades. Kontrol positif yang digunakan adalah klindamisin, sedangkan untuk kontrol negatif adalah aquades. Parameter yang diukur adalah zona hambat, yaitu area bening di sekitar cakram adalah tempat tidak ada pertumbuhan bakteri, diukur dalam satuan milimeter. Hasil uji antibakteri kombinasi buah takokak dan limbah kulit pisang kepok pada perbandingan 2:1 memiliki daya hambat yang paling tinggi adalah pada konsentrasi 15%, 20% dan 25% berturut-turut adalah 16,03 mm, 17,10 mm dan 18,63 mm. Kontrol positif menghasilkan daya hambat sebesar 35,45 mm sedangkan kontrol negatif tidak memiliki daya hambat. Selanjutnya disimpulkan bahwa kombinasi ekstrak buah takokak dan kulit pisang kepok efektif dalam menghambat pertumbuhan bakteri Propionibacterium acnes.Kata kunci: Solanum torvum swartz; Musa balbisiana; ekstrak etanol 70%; maserasi; Propionibacterium acnes
AN ANALYSIS OF DRUG INVENTORY CONTROL EFFICIENCY USING ALWAYS BETTER CONTROL, VITAL ESSENTIAL NON-ESSENTIAL, AND ECONOMIC ORDER QUANTITY METHODS: A CASE STUDY AT ASSALAAM MEDICARE Arief, Khunaisa; Nafisah, Umi; Amalia, Annora Rizky
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 1 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i1.578

Abstract

In-depth control of pharmaceutical inventory is critical, especially in healthcare facility units to ensure the availability of drugs to minimize the risk of stagnation (excess inventory of drugs) and inventory vacancies (shortage or empty level of inventory). The purpose of this study is to determine how inventory level control is carried out at Assalaam Medicare pharmacy using the ABC (Always, Better, Control), VEN (Vital, Essential, Non Essential), and EOQ (Economic Order Quantity) methods for the period January to March 2024. Based on ABC analysis of a total of 572 items of drugs, 151 items of drugs are classified into group A which accounts for 27.970 or 65%, with an investment value of 75% of the total, group B with 215 drug items with a consumption of 10,236 or 24% and an investment of 20%, and group C with 206 items which has a consumption of 4,521 or 11% and an investment of 6%. From the VEN analysis, 26 drug items belong to the vital (V) drug class of group A as an essential service segment. According to EOQ, the highest optimum order quantity is 2.061 items and the lowest optimum value is 17 items for a single order.
IDENTIFIKASI SENYAWA FITOKIMIA EKSTRAK DAUN MIANA (COLEUS ATROPURPUREUS L. BENTH) Nurrahman, Alfina; Amalia, Annora Rizky
Prosiding Seminar Informasi Kesehatan Nasional 2025: SIKesNas 2025
Publisher : Fakultas Ilmu Kesehatan Universitas Duta Bangsa Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47701/vdhxvf11

Abstract

Penelitian ini bertujuan untuk mengidentifikasi kandungan fitokimia dari ekstrak etanol daun miana dengan pengujian organoleptis, kadar air, bebas alkohol, serta uji fitokimia kualitatif. Ekstraksi dilakukan dengan metode maserasi menggunakan pelarut etanol 70%. Hasil menunjukkan bahwa ekstrak memiliki karakteristik organoleptis berwarna ungu tua, berbau khas aromatik, dan berbentuk kental. Kadar air ekstrak menunjukkan nilai 7,48 %, uji bebas alkohol menunjukkan hasil negatif, serta hasil uji fitokimia kualitatif menunjukkan adanya senyawa alkaloid, flavonoid, tanin, dan steroid. Hasil ini menunjukkan bahwa ekstrak etanol daun miana mengandung senyawa bioaktif yang potensial untuk dikembangkan dalam pengobatan herbal.
UJI KONSENTRASI HAMBAT MINIMUM (KHM) MINYAK ATSIRI ADAS (FOENICULUM VULGARE MILL.) TERHADAP PERTUMBUHAN BAKTERI PROPIONIBACTERIUM ACNES DENGAN METODE SUMURAN Amalia, Annora Rizky
Jurnal Review Pendidikan dan Pengajaran Vol. 7 No. 3 (2024): Vol. 7 No. 3 (2024): Volume 7 No 3 Tahun 2024 (Special Issue)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jrpp.v7i3.32115

Abstract

Jerawat (acne vulgaris) merupakan suatu kondisi inflamasi yang secara umum terjadi pada bagian organ kulit. Jerawat dapat disebabkan oleh bakteri Staphylococcus aureus, Propionibacterium acnes dan Staphylococcus epidermidis. Penelitian ini bertujuan untuk mengetahui aktivitas minyak atsiri adas (foeniculum vulgare mill.) terhadap pertumbuhan bakteri propionibacterium acnes. Pengujian aktivitas antibakteri dilakukan menggunakan metode difusi agar dengan cara sumuran pada variasi konsentrasi 2%, 4%, 6% dan 8% . Kontrol positif yang digunakan pada penelitian ini adalah klindamisin dan kontrol negatif menggunakan DMSO 10%. Hasil uji daya hambat yang diperoleh dari pengujian minyak adas pada konsentrasi 2% memiliki daya hambat rata-rata 7,5mm, konsentrasi 4% memiliki daya hambat rata-rata 12 mm, konsentrasi 6% memiliki daya hambat rata-rata 17 mm, dan pada konsentrasi 8% memiliki daya hambat rata-rata 19 mm. Kontrol positif klindamisin memiliki daya hambat sebesar 14 mm maka disimpulkan bahwa Konsentrasi Hambat Minimum (KHM) minyak atsiri adas terhadap bakteri jerawat yaitu Propionibacterium acnes pada konsentrasi 2% dengan diameter zona hambat sebesar 7,5 mm.
Uji Potensi Fraksi n-Heksan Daun Keji Besi (Hemigraphis repanda L.) Sebagai Antibakteri Terhadap Escherichia Coli dan Bacillus Cereus Beserta Penentuan Konsentrasi Hambat Minimum (KHM) Alfina Nurrahman; Rahmat Hidayat; Annora Rizky Amalia
Journal of Health, Medical, and Psychological Studies Vol 1 No 2 (2025): December: Sanitas: Journal of Health, Medical, and Psychological Studies
Publisher : CV SCRIPTA INTELEKTUAL MANDIRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.65310/29v9p164

Abstract

This study aimed to evaluate the antibacterial potential of the n-hexane fraction of Keji Besi leaves (Hemigraphis repanda L.) against Escherichia coli and Bacillus cereus, as well as to determine its Minimum Inhibitory Concentration (MIC). Keji Besi leaves were extracted by maceration using 96% ethanol, followed by liquid–liquid fractionation with n-hexane. The antibacterial activity was assessed using the disc diffusion method, while MIC values were determined using the broth dilution method. Phytochemical screening revealed that the n-hexane fraction predominantly contained steroid and triterpenoid compounds. The disc diffusion assay showed that the n-hexane fraction exhibited stronger inhibitory activity against B. cereus than E. coli, with the largest inhibition zone observed at an 80% concentration. MIC determination indicated that the MIC value for B. cereus was 40% (w/v), whereas E. coli required a higher concentration of 80% (w/v) to inhibit bacterial growth. These findings suggest that the n-hexane fraction of Keji Besi leaves demonstrates selective antibacterial activity, particularly against Gram-positive bacteria. Therefore, this fraction has promising potential to be developed as a natural antibacterial agent, especially for infections caused by Gram-positive pathogens.
COST OF ILLNESS STROKE TREATMENT: A SYSTEMATIC REVIEW Izzah, Raihana Nurul; Alia, Dina Fatma; Amalia, Annora Rizky; Sari, Yunita Dian Permata
Medical Journal of Nusantara Vol. 5 No. 1 (2026): Medical Journal of Nusantara (MJN)
Publisher : Tahta Media Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55080/mjn.v5i1.1957

Abstract

Cardiovascular disease remains the leading cause of death worldwide, with stroke playing a significant role in increasing morbidity, mortality, and the global economic burden. This study aimed to systematically review the cost of illness and health expenditure associated with stroke across different countries. A systematic review was conducted using PubMed, ScienceDirect, and Springer databases for articles published between 2021 and 2026, following PRISMA guidelines. Studies included in the criteria were original research that reported direct and/or indirect costs due to stroke, both in primary health care facilities and in hospitals. Data extraction, screening, and quality assessment were performed using the CHEERS checklist. A total of 13 studies met the inclusion criteria. The findings showed that most studies (76%) applied the Cost Of Illness (COI) approach, while the rest used Health Expenditure (HE) methods. Direct medical costs, particularly those from inpatient care, constitute the largest component of stroke-related expenditures. Cost estimates show considerable variation between countries, with expenditures tending to be higher in high-income countries than in middle-income countries. Clinical severity, length of hospital stay, stroke subtype, and sociodemographic factors were identified as key determinants influencing total costs. Indirect cost components such as lost productivity and premature death also contribute significantly, but their reporting has not been consistent across studies. In conclusion, stroke imposes a substantial and heterogeneous economic burden influenced by methodological approaches, perspectives, and healthcare system differences. Comprehensive evaluation including both direct and indirect costs is essential to support effective health policy and resource allocation.
Co-Authors Alfina Nurrahman Alia, Dina Fatma Andany Oktamia Ningtyas Hartoyo Ardhia Intan Cahyani Arief, Khunaisa Ariska Rahmawati Utami Deny Balita Wulandari Dewi Weni Sari Diyan Sakti Purwanto Ela Fransisca Christa S Izzah, Raihana Nurul Kharisma Jayak Pratama Muhammad Dani Riano Muhammad Firdaus Nafisah, Umi Natasya Maya Isabella Nurrahman, Alfina Rahmat Hidayat Riyan Setiyanto Riyan Setiyanto Sari, Dewi Weni Sari, Yunita Dian Permata Siski Nautika Dewi Vania Santika Putri Yunita Dian Permata Sari Yunita Dian Permata Sari Zulaika Febru Zalsabila