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All Journal Science and Technology Indonesia Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Indonesian Journal of Pharmaceutical and Clinical Research GANDRUNG: Jurnal Pengabdian Kepada Masyarakat International Journal Of Science, Technology & Management (IJSTM) Narra J Nusantara Scientific Medical Research Journal Journal of Pharmaceutical and Sciences. Parapemikir Jurnal Ilmiah Farmasi
Hafid Syahputra
Department Of Pharmaceutical Chemistry, Faculty Of Pharmacy, Universitas Sumatera Utara, Sumatera Utara, Medan 20155, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Isolation and identification of diosgenin and flavonoids compound from ethanol extract of Dioscorea hispida Dennst. tuber hafid syahputra; Masfria; Meuthia Rizka Amana; Muhammad Rivai
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 1 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i1.15994

Abstract

The tuber of Dioscorea hispida Dennst. has potential for development as a synthetic pharmaceutical ingredient due to the presence of secondary metabolites such as diosgenin and flavonoids, which exhibit biological activity within the body. Further exploration of this potential requires the isolation and identification of these compounds. Diosgenin was isolated from the ethanol extract using thin-layer chromatography, while flavonoids were isolated from the ethyl acetate fraction using paper chromatography. The pure isolates of both compounds were identified using UV-Vis spectrophotometry and FT-IR spectroscopy. The UV-Vis spectrophotometric analysis of diosgenin revealed maximum absorption wavelengths at 205 and 453 nm. Flavonoid isolates exhibited maximum absorption wavelengths of 264 nm for the first isolate, 265 nm for the second, 276 nm for the third, and 272 nm for the fourth. FT-IR spectroscopic analysis of the diosgenin isolate indicated the presence of functional groups such as -OH, aromatic C=C, and aromatic C-O, while the flavonoid isolate showed the presence of O-H, aromatic C-H, aliphatic C-H, C=O, C=C, and C-O. These identification results confirm that the isolates obtained indeed contain diosgenin and flavonoids.
Phytochemical Screening and Determination of Phenolic and Flavonoid Contents in Ethanol Extract of Phyllanthus emblica L. Fruit Hafid Syahputra
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 2 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i2.18235

Abstract

Phyllanthus emblica L. fruit is known for its potent antioxidant activity, closely associated with its phenolic and flavonoid content. This study aims to analyse the secondary metabolite composition and determine the total phenol and flavonoid levels in Phyllanthus emblica fruit. The extraction process was carried out using the maceration method with 96% ethanol as the solvent, followed by a rotary evaporator evaporation. The ethanol extract was subjected to phytochemical screening with colour reagents, and the total phenol and flavonoid contents were assessed using a colourimetric method. TheFolin–Ciocalteu reagent was employed for complex phenolic compounds, with gallic acid as the standard reference. The total flavonoid content was determined using the aluminium chloride method, with quercetin as the standard. The results indicated that the ethanol extract of Phyllanthus emblica fruit contained alkaloids, saponins, flavonoids, tannins, triterpenoids, and glycosides. The study found that the total phenol content was 61.1271±3.86 mg GAE/g extract, while the total flavonoid content was 3.3742±0.06 mg QE/g extract.
Stunting Prevention Movement Through Fortification of Moringa Leaves and Mung Bean Flour in Cookies as PMT (Supplementary Feeding) For Toddlers in Medan Sunggal District Denny Satria; Aminah Dalimunthe; Hafid Syahputra; Vivi Asfianti; Syukur Berkat Waruwu
GANDRUNG: Jurnal Pengabdian Kepada Masyarakat Vol. 6 No. 2 (2025): GANDRUNG: Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Olahraga dan Kesehatan, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/gandrung.v6i2.4654

Abstract

Stunting is a serious problem and is also a major nutritional problem. The problem of stunting has a quite serious impact. It can be short-term related to morbidity and mortality in infants and toddlers, medium-term related to low intellectual and cognitive ability, and long-term related to the quality of human resources and degenerative disease problems in adulthood. The average prevalence of stunting in Indonesia from 2015 to 2017 was 31.4%, far above the WHO limit of 20%. The government with Presidential Decree No. 42/2013 has established a national movement for the first 1000 days of life to improve the nutritional status of toddlers as an effort to handle stunting in Indonesia. Because of the mothers' lack of knowledge about stunting, we were moved to do community service in Medan Sunggal District. Based on this thought, this community service activity is carried out to educate women (community) about the importance of good and correct food processing regarding nutrition/nutrition intake for toddlers by making mothers health cadres in the family in the application of functional food processing from natural ingredients such as moringa leaves and mung beans for stunting prevention in Medan Sunggal District.
Uji Aktivitas Antioksidan Teh Herbal Biji Durian (Durio zibethinus Murr.) dengan Tambahan Daun stevia (Stevia rebaudiana Bertoni) sebagai Pemanis Alami dengan Metode DPPH Andry, Muhammad; Ramadaini, Tiara; Marseli, Cindy; Nurfitriyana, Nurfitriyana; Azzahra, Rafifah; Syahputra, Hafid; Shiyan, Shaum
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1070

Abstract

Free radicals are an important health concern due to their role in the development of various diseases. Antioxidants, capable of neutralizing free radicals, are abundant in plants such as durian seeds (Durio zibethinus Murr.) and stevia leaves (Stevia rebaudiana Bertoni). Herbal tea formulated from these materials has potential as an alternative functional drink because both contain phenolic compounds with antioxidant activity. This study aimed to evaluate the potential of durian seeds and stevia leaves as herbal tea with antioxidant properties. The research involved sample collection, identification, preparation of simplicia, characterization, formulation of herbal tea, quality testing, and determination of antioxidant activity. The simplicia characteristics of durian seeds and stevia leaves showed water content of 6.16% each, water-soluble extract of 35% and 15.8%, ethanol-soluble extract of 25.5% and 14.6%, total ash of 0.73% and 0.3%, and acid-insoluble ash of 0.5% and 0.26%. Quality testing of the herbal tea showed water content of 2.18%, total ash of 3.90%, water-soluble ash of 73.85%, and acid-insoluble ash of 3.80%. Antioxidant activity based on IC50 values was 68.45 ± 1.32 ppm for durian seed tea, 61.6 ± 1.05 ppm for stevia tea, 39.28 ± 0.98 ppm (1:1), 44.64 ± 1.11 ppm (1:2), and 42.32 ppm ± 1.07 (2:1). These results indicate that combining durian seeds and stevia leaves can enhance antioxidant activity compared to individual extracts. Overall, durian seeds and stevia leaves can be developed into herbal tea formulations with very strong antioxidant activity, as reflected in their ability to reduce DPPH radicals. Radikal
Co-Authors Ade Sri Rohani Aminah Dalimunthe Aminah Dalimunthe Bihar, Syamsul Denny Satria Erna Mutiara Henni Cintya Julia Reveny Kardiasyah, Alzi Lisda Rimayani Lubis, Netty D. Marseli, Cindy Marwin Witarman Masfria Masfria Masfria Meuthia Rizka Amana Muchlisyam Muhammad Andry Muhammad Fauzan Lubis Muhammad Rivai Nazliniwaty Nazliniwaty* Nur Aira Juwita Nurfitriyana Nurfitriyana Nurul Suci Rafifah Azzahra Ramadaini, Tiara Ririn Astyka Shafira Mahrani Shaum Shiyan Sumaiyah Sumaiyah Sumaiyah Syarani, Fajrinur Syukur Berkat Waruwu Vivi Asfianti Yasmeen Nazhifah Yuliasmi, Sri