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All Journal Jurnal Anestesi Perioperatif JOURNAL OF ELECTRICAL AND SYSTEM CONTROL ENGINEERING Majalah Kedokteran Nusantara The Journal Of Medical School Buletin Farmatera Sumatera Medical Journal International Journal of Islamic and Complementary Medicine Jurnal Neuroanestesi Indonesia Jurnal Pandu Husada Jurnal Sains, Teknologi dan Kesehatan
Hasanul Arifin
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Religion Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Education Electrical & Electronics Engineering Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Veterinary

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Journal : Buletin Farmatera

 1 
Potensi Habbatussauda ( Nigella Sativa ) Terhadap Pencegahan Demensia Alzheimer Arifin, Hasanul
Buletin Farmatera Vol 9, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v9i3.23405

Abstract

Abstract: Dementia is a progressive and degenerative clinical syndrome, that affects memory, thinking ability, behaviour, emotions and personality that interfere with daily life activities. The aetiology of dementia is linked to the involvement of vascular, inflammatory, oxidative stress and neurotoxicity that causes neurodegenerative brain pathologies that can contribute to cognitive impairment and dementia. Multidomain interventions targeting multiple risk factors for effective prevention including dietary supplements from traditional plants. Nigella sativa (NS) is a traditional plant native to the Mediterranean Area and Southwest Asia that has long been used to maintain human health. Nigella Sativa has a significant content of thymoquinone (TQ) as a bioactive element of 30-48% of the total NS compounds. Several in vitro and in vivo preclinical studies and clinical trials that are still limited to non-dementia humans show that TQ has a positive effect on cognitive impairment through oxidative stress control mechanisms, vascular health, anti-inflammatory, maintenance of nerve cell integrity and improvement of neurotrophic regulatory factors which are promising in preventing cognitive decline. Nigella sativa serves as a potential dietary supplement to prevent the progression of Alzheimer's disease but requires long-term investigation and follow-up research to test safety and toxicity and compare its effectiveness at different stages of dementia such as Alzheimer's disease.
Myopia Is Related to Head Pain in Students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara Arifin, Hasanul; Uljannah, Nisa
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25366

Abstract

Abstract: Myopia was found to be a common cause of headaches, and about 28% of the patients studied had myopia. This study was conducted with the aim of finding out the relationship between myopia and headache in students with the target students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara. This study is an analytical observational research with a cross-sectional approach involving 72 research subjects of students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara, and using an online questionnaire with a Google form application to obtain primary data.  Of the group of students who suffered from mild myopia, 23.5% suffered from mild headaches, 61.8% had moderate headaches, and 14.7% had severe headaches. Meanwhile, in the group of students who suffered from moderate myopia, 6.9% suffered from mild headaches, 58.6% moderate headaches and 34.5% severe headaches. For the group of students who suffer from severe myopia, no one experiences mild or moderate headaches, but there are 100% suffer from severe headaches. The Chi Square test shows the sum of 0.000. It can be concluded that myopia is related to headaches in medical students of the Universitas Muhammadiyah Sumatera Utara.
The Relationship Between Elevated D-Dimer Levels And The Incidence Of Ischemic Stroke In Covid-19 Patients At Drs H. Amri Tambunan Regency, Deli Serdang Regency Novani, Dinda Dwi; Surya, Anita; Arifin, Hasanul; Irma, Fani Ade
Buletin Farmatera Vol 12, No 1 (2027)
Publisher : Universitas Muhammadiyah Sumatera Utara

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Abstract: Acute ischemic stroke spreads from infected individuals, whether they are already showing symptoms or not. The initial symptom that often appears in infected individuals is fever, with a body temperature between 38.1 and 39°C. The mechanism of stroke in COVID-19 patients is caused by an increase in D-Dimer and fibrinogen, which are part of the coagulation pathway. Coagulation is related to the systemic inflammatory response caused by infection. The purpose of this study was to understand and further examine the relationship between increased D-Dimer levels in ischemic stroke patients infected with COVID-19 at Drs. H. Amri Tambunan Regional Hospital, Deli Serdang Regency. This research method is a retrospective descriptive study using a cross-sectional research design. This study used secondary data derived from medical records of COVID-19 patients with ischemic stroke events at Drs. H. Amri Tambunan Regional Hospital, Deli Serdang Regency. H. Amri Tambunan, Deli Serdang Regency, 2021. The results of the Chi-square test were 0.239 (P-value 0.05), which means there is no significant relationship between increased D-Dimer and the incidence of ischemic stroke and hemorrhagic stroke in COVID-19 patients. The conclusion obtained was that there was no significant relationship between increased D-Dimer and the risk of ischemic stroke in COVID-19 patients.
Co-Authors Affandi Ance Roslina Andri Faizal L Andri, Mufti Anita, Surya Arya Rudi Nasution Dadik Wahyu Wijaya Fadinie, Wulan Fithri, Dewi Yuliana Franz Josef Tarigan Hafniana, Hafniana Hanafie, Achsanuddin Harahap, Muhammad Alwi Ripay Heru Kurniawan Heru Kurniawan Ikbar, Luthfi Indri Seta Septadina Irina, Sinta Irina, Sinta Irma, Fani Ade Mufti Andri Mursin, Chairul M. Napitupulu, Olivia Des Vinca Albahana Nasution, Sani P Nirmala, Arum Puspita Novani, Dinda Dwi Putra, Angga Permana Rehatta, Nancy Margareta Rehatta, Nancy Margareta Saleh, Siti Chasnak Saleh, Siti Chasnak Siregar, Rahmat Fauzi Syamsul Bahri Uljannah, Nisa Umar, Nazaruddin Umar, Nazaruddin Wijaya, Dadik Wahyu Wijaya, Dadik Wahyu