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Journal : Buletin Farmatera

Potensi Habbatussauda ( Nigella Sativa ) Terhadap Pencegahan Demensia Alzheimer Arifin, Hasanul
Buletin Farmatera Vol 9, No 3 (2024)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v9i3.23405

Abstract

Abstract: Dementia is a progressive and degenerative clinical syndrome, that affects memory, thinking ability, behaviour, emotions and personality that interfere with daily life activities. The aetiology of dementia is linked to the involvement of vascular, inflammatory, oxidative stress and neurotoxicity that causes neurodegenerative brain pathologies that can contribute to cognitive impairment and dementia. Multidomain interventions targeting multiple risk factors for effective prevention including dietary supplements from traditional plants. Nigella sativa (NS) is a traditional plant native to the Mediterranean Area and Southwest Asia that has long been used to maintain human health. Nigella Sativa has a significant content of thymoquinone (TQ) as a bioactive element of 30-48% of the total NS compounds. Several in vitro and in vivo preclinical studies and clinical trials that are still limited to non-dementia humans show that TQ has a positive effect on cognitive impairment through oxidative stress control mechanisms, vascular health, anti-inflammatory, maintenance of nerve cell integrity and improvement of neurotrophic regulatory factors which are promising in preventing cognitive decline. Nigella sativa serves as a potential dietary supplement to prevent the progression of Alzheimer's disease but requires long-term investigation and follow-up research to test safety and toxicity and compare its effectiveness at different stages of dementia such as Alzheimer's disease.
Myopia Is Related to Head Pain in Students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara Arifin, Hasanul; Uljannah, Nisa
Buletin Farmatera Vol 10, No 3 (2025)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v10i3.25366

Abstract

Abstract: Myopia was found to be a common cause of headaches, and about 28% of the patients studied had myopia. This study was conducted with the aim of finding out the relationship between myopia and headache in students with the target students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara. This study is an analytical observational research with a cross-sectional approach involving 72 research subjects of students of the Faculty of Medicine, Universitas Muhammadiyah Sumatera Utara, and using an online questionnaire with a Google form application to obtain primary data.  Of the group of students who suffered from mild myopia, 23.5% suffered from mild headaches, 61.8% had moderate headaches, and 14.7% had severe headaches. Meanwhile, in the group of students who suffered from moderate myopia, 6.9% suffered from mild headaches, 58.6% moderate headaches and 34.5% severe headaches. For the group of students who suffer from severe myopia, no one experiences mild or moderate headaches, but there are 100% suffer from severe headaches. The Chi Square test shows the sum of 0.000. It can be concluded that myopia is related to headaches in medical students of the Universitas Muhammadiyah Sumatera Utara.