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All Journal PHARMACON CHEMISTRY PROGRESS Transmisi JPSE (Journal of Physical Science and Engineering) Briliant: Jurnal Riset dan Konseptual JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JURNAL PENDIDIKAN TAMBUSAI Jurnal Agritechno Jurnal Abdi Insani Community Empowerment Borneo Journal of Pharmacy Jurnal Lentera: Penelitian dan Pengabdian Masyarakat
Hariyanto, Yuanita Amalia
Universitas Sam Ratulangi (Scopus ID: 57202791490)
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Journal : PHARMACON

 1 
Uji Aktivitas Antioksidan Ekstrak Etanol Lissoclinum patella Yang Diperoleh Dari Pantai Parentek Kabupaten Minahasa Pricillia Esterlita Mintadoa; Adithya Yudistira; Yuanita Amalia Hariyanto
PHARMACON Vol. 13 No. 2 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55065

Abstract

Tunicates are one of the marine organisms that have the potential to produce secondary metabolite compounds that have many benefits. One of the functions of secondary metabolites is as antioxidants. Antioxidants are compounds that can inhibit the oxidation process caused by free radicals. This study aims to determine the antioxidant activity of ethanol extract produced by Lissoclinum patella using DPPH (1,1-diphenyl-2-picrylhydrazyl) method obtained from Parentek Beach, Minahasa Regency. This research is a laboratory experiment with maceration method using 95% ethanol solvent. Antioxidant testing using DPPH (1,1-diphenyl-2-picrylhydrazyl) method with 5 series of sample concentrations (20, 40, 60, 80, 100 ppm) measured using UV-Vis spectrophotometer with absorbance value measured at 517 nm wavelength. The results of the study obtained the average percent inhibition value obtained at concentrations of 20, 40, 60, 80, 100 ppm respectively were 48.06%, 56.52%, 62.27%, 63.80%, 68.03%. This study concludes that Lissoclinum patella tunicata extract has antioxidant activity at concentrations of 20, 40, 60, 80, 100 ppm.
Uji Aktivitas Antioksidan Ekstrak Etanol Didemnum molle Yang Diperoleh Dari Pamtai Parentek Kabupaten Minahasa Rizal Musafa Medica; Adithya Yudistira; Yuanita Amalia Hariyanto; Imam Jayanto
PHARMACON Vol. 13 No. 2 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55153

Abstract

Didemnum molle is one of the tunicates marine biota whose habitat can be found in Indonesian coral reef waters. This marine animal is green which indicates the content of secondary metabolites as a form of self-defense. Secondary metabolite compounds in Didemnum molle have the potential to have antioxidant effects that can fight free radicals. This study aims to determine the antioxidant activity of Didemnum molle ethanol extract with DPPH method and calculation of percent inhibition value. The calculation results showed 47.94% (20 ppm), 58.75% (40 ppm), 60.45% (60 ppm), 63.15% (80 ppm), and 70.74% (100 ppm). These values indicate that all concentration series have antioxidant activity but are effective as antioxidants at concentrations of 40 ppm, 60 ppm, 80 ppm, and 100 ppm because they have a percent inhibition above 50%.
Uji Aktivitas Antioksidan Ekstrak Etanol Spons Aaptos aaptos yang Diperoleh dari Pantai Selatan Kabupaten Minahasa Jesikha Sharen Salikode; Adithya Yudistira; Yuanita Amalia Hariyanto
PHARMACON Vol. 13 No. 1 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.49266

Abstract

Spons Aaptos aaptos merupakan salah satu biota laut yang sangat prospektif dan memiliki kemampuan menghasilkan senyawa bioaktif yang potensial untuk dijadikan sebagai sumber obat-obatan baru. Antioksidan adalah zat yang bisa mencegah terjadinya proses oksidasi, karena itu antioksidan sangat bermanfaat bagi kesehatan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak etanol yang dihasilkan oleh spons Aaptos aaptos dengan menggunakan metode DPPH (1,1-difenil-2-pikrilhidrazil). Jenis penelitian ini adalah penelitian eksperimen laboratorium. Hasil analisis data %inhibisi yang didapat adalah 52,6% (25 ppm); 72,5% (50 ppm); 82,9% (75 ppm); dan 87,4% (100 ppm). Ekstrak etanol spons Aaptos aaptos yang diperoleh dari Pantai Selatan Kabupaten Minahasa memiliki aktivitas antioksidan tertinggi pada konsentrasi 100 ppm yaitu 87,4%. Kata kunci: Aaptos aaptos, aktivitas antioksidan, DPPH, Kabupaten Minahasa
Evaluation of Antioxidant Activity of Ethanol Extract from Phyllospongia lamellosa Obtained in Parentek Beach, Minahasa Regency Karunia Ritje Virginia Rintjap; Adithya Yudistira; Yuanita Amalia Hariyanto
PHARMACON Vol. 13 No. 3 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55294

Abstract

Sponges are one of the components of coral reef biota that are quite widespread. Almost 75% of the sponge species found in the waters are classes of Demospongiae. Asymmetrical in shape, demospongiae grow in various sizes from small to more than 2 meters. This study aims to determine the antioxidant activity of ethanol extract of Phyllospongia lamellosa obtained using DPPH method. The results of data analysis of % inhibition values are 20 ppm concentration (41.80%), 40 ppm concentration (43.78%), 60 ppm concentration (46.65%), 80 ppm concentration (47.25%), 100 ppm concentration (48.42%). This shows that the Phyllospongia lamellosa sponge sample obtained from Parentek Beach, Minahasa Regency has antioxidant effectiveness but is not active because the highest percent inhibition value at a concentration of 100 ppm is only 48.42%.
Antibacterial Efficay Test of Ethanol Extract of Yaki Areca Nut (Areca vestiaria) Against the Growth of Propionibacterium acnes, the Cause of Acne. Pabundu, Daniel; Simbala, Herny; Hariyanto, Yuanita Amalia
PHARMACON Vol. 13 No. 3 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55524

Abstract

A bacterial skin infection that is often experienced by everyone, especially in adolescence, is acne(Acne vulgaris). Acne is caused by the accumulation of excess oil in the skin, thus becoming a medium for bacterial growth, which causes acne. The use of natural antibiotics can be a therapeutic option in the treatment of acne. One of the plants that potentially has antbacterial activity is Pinang Yaki (Areca vestiaria). The purpose of this study was to determine the antibacterial activity of ethanol extract of areca nut fruit against the growth of Propionibacterium acnes that causes acne. The test of antibacterial activity of areca nut extract with the pitting method found that at a concentration of 10% the antibacterial activity was included in the weak group, 20% was included in the medium group, while those included in the strong group in inhibiting the growth of Propionibacterium acnes were extracts with concentrations of 40%, 60% and 80%..
Co-Authors Abdullah, Surya Sumantri Adikila, Gregorius Giani Adithya Yudistira Aditya Lapu Kalua Ahmad Taufiq Antasionasti, Irma ASARI Asviyatu Nisa' Azis, Rosidi Bakti, Andi Ikhtiar BUKROANAH AMIR MAKKAU DEBY AFRIANI MPILA Elly Suoth Fatimawali . Hakim, M Helmi Herny E.I. Simbala Hidayatun Nasikhah Imam Jayanto Imam Jayanto Irma Antasionasti Jaya Edy, Hosea Jayanto, Imam Jesikha Sharen Salikode Julianri Sari Lebang, Julianri Sari Jumriadi Karunia Ritje Virginia Rintjap Lestari, Utami Sasmita Mahendra Kusuma Nugraha Meilani Jayanti Monica, Anindya Bella Muhammad Helmi Hakim Mujiyanti, Tri Pabundu, Daniel Parwanto, Edy Pricillia Esterlita Mintadoa Ratika Sekar Ajeng Ananingtyas Rizal Musafa Medica Salsabila, Unik Hanifah Sri Sudewi, Sri Sunaryono Tri Mujiyanti TRINA EKAWATI TALLEI Yuniar Alam Yuniar Alam, Yuniar