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All Journal PHARMACON CHEMISTRY PROGRESS Transmisi JPSE (Journal of Physical Science and Engineering) Briliant: Jurnal Riset dan Konseptual JMM (Jurnal Masyarakat Mandiri) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ JURNAL PENDIDIKAN TAMBUSAI Jurnal Agritechno Jurnal Abdi Insani Community Empowerment Journal of Community Empowerment Borneo Journal of Pharmacy Jurnal Lentera: Penelitian dan Pengabdian Masyarakat Jurnal Lentera Farma Journal of Social Sciences and Technology for Community Service
Hariyanto, Yuanita Amalia
Universitas Sam Ratulangi (Scopus ID: 57202791490)
Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Antibacterial Efficay Test of Ethanol Extract of Yaki Areca Nut (Areca vestiaria) Against the Growth of Propionibacterium acnes, the Cause of Acne. Pabundu, Daniel; Simbala, Herny; Hariyanto, Yuanita Amalia
PHARMACON Vol. 13 No. 3 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55524

Abstract

A bacterial skin infection that is often experienced by everyone, especially in adolescence, is acne(Acne vulgaris). Acne is caused by the accumulation of excess oil in the skin, thus becoming a medium for bacterial growth, which causes acne. The use of natural antibiotics can be a therapeutic option in the treatment of acne. One of the plants that potentially has antbacterial activity is Pinang Yaki (Areca vestiaria). The purpose of this study was to determine the antibacterial activity of ethanol extract of areca nut fruit against the growth of Propionibacterium acnes that causes acne. The test of antibacterial activity of areca nut extract with the pitting method found that at a concentration of 10% the antibacterial activity was included in the weak group, 20% was included in the medium group, while those included in the strong group in inhibiting the growth of Propionibacterium acnes were extracts with concentrations of 40%, 60% and 80%..
Training on antibacterial liquid soap making from nipah leaf extract to support SDGs-3 good health and well being Yuanita Amalia Hariyanto; Aditya Lapu Kalua; Bukroanah Amir Makkau; Imam Jayanto
Community Empowerment Vol 9 No 12 (2024)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12570

Abstract

Wori Village, located in the buffer zone of the Likupang Tourism Special Economic Zone (KEK), requires development of both its natural and human resources. Natural resource optimization can be achieved through diversification, specifically by producing liquid soap from the nipah plant. Human resource development necessitates increased public awareness of skin health and personal hygiene. This Community Service aimed to educate the Wori Village community on personal hygiene and provide a practical solution for reducing skin diseases through the use of antibacterial liquid soap. The methodology comprised socialization, training, technology application, mentoring, evaluation, and plans for program sustainability. The resulting NIPALS soap met quality standards, exhibiting a pH of 7. Evaluation demonstrated a 96.7% increase in participants' knowledge of personal hygiene and soap-making (pre-test vs. post-test). Furthermore, 95.5% of participants expressed satisfaction with the soap (4.5% considered it average). Positive user experiences included a 97% absence of itching, 76.7% reporting a tightening effect, and 70% noting moisturization. These results, supported by positive hedonic test results, confirm the successful production of liquid soap by the participants.
PENINGKATAN KAPASITAS MASYARAKAT DALAM UPAYA PENCEGAHAN INFEKSI KULIT DAN PRODUKTIVITAS EKONOMI MELALUI PELATIHAN PEMBUATAN SABUN-VCO DI DESA MINAESA MINAHASA UTARA Hariyanto, Yuanita Amalia; Jayanti, Meilani; Lebang, Julianri Sari
Jurnal Abdi Insani Vol 12 No 1 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i1.2083

Abstract

Considering skin disorders can now spread through a variety of media, it is crucial for the public to understand skin health issues. Skin conditions are now among the most prevalent illnesses in coastal towns. People who live near the coast are more likely to experience skin health issues. Numerous elements, such as humidity, sun exposure, personal cleanliness, and water quality, contribute to this. The goal of this project is to teach the Minaesa Village community how to make liquid soap from VCO and to educate them about personal hygiene. On-the-job training is the approach used in the PKM. Direct field visits, identifying the partners' issues and requirements, offering solutions, conducting activities to satisfy the partners' needs, and evaluation are all part of this approach. The pH of the VCOLS soap manufactured is 7, which means that it satisfies quality criteria. According to the evaluation's findings, participants' knowledge increased by 86.5%. More than 82.2% of participants expressed pleasure with the VCOLS soap, according to the evaluation of the satisfaction questionnaire about the created soap, while 17.8% expressed no opinion. The findings of the perception survey of the VCOLS soap, on the other hand, indicate that no one itched after using it, 70% thought it was non-greasy, and 67.7% thought it was hydrating. The evaluation's findings indicate that participants' knowledge of skin care and soap-making methods has grown. According to the results of the perception questionnaire, participants have successfully produced liquid soap from VCO that satisfies quality standards. It is also envisaged that the expertise offered, particularly in the creation of liquid soap from VCO, can be further enhanced through the community service activities in Minaesa Village.
In Silico Analysis of the Antigastritis Activity of Gedi (Abelmoschus manihot) Flower Flavonoids on H2 Receptor Adikila, Gregorius Giani; Hariyanto, Yuanita Amalia; Tallei, Trina Ekawati; Suoth, Elly Juliana; Sudewi, Sri; Fatimawali, Fatimawali
Borneo Journal of Pharmacy Vol. 8 No. 3 (2025): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v8i3.7586

Abstract

Gastritis remains a highly prevalent health concern in Indonesia, underscoring a continuous demand for innovative therapeutic interventions. The flower of Abelmoschus manihot, commonly known as Gedi, has garnered interest for its potential antigastritis properties, specifically as an H2 antagonist, attributed to its rich flavonoid content. This study aimed to rigorously evaluate the H2 antagonist potential of A. manihot flowers using an in silico approach. Our research methodology involved assessing the physicochemical and pharmacokinetic profiles, alongside molecular docking simulations, of ten prominent flavonoid ligands identified in A. manihot flowers: quercetin, myricetin, myricetin-3-O-glucoside, myricetin-3'-O-glucoside, quercetin-3'-O-glucoside, hibifolin, isoquercetin, hyperoside, quercetin-3-O-robinobioside, and rutin. The analysis of physicochemical and pharmacokinetic properties encompassed Lipinski's Rule of Five and comprehensive ADMET predictions. Molecular docking simulations focused on evaluating binding energies and interactions with crucial H2 receptor residues: Asp98, Asp186, Val99, and Phe254. Among the ligands being assessed, quercetin demonstrated the most favorable physicochemical-pharmacokinetic characteristics and exhibited superior binding affinities and interactions in the molecular docking analysis. These findings collectively suggest that A. manihot flower holds significant promise as a natural source for antigastritis agents, specifically through its potential H2 antagonist activity, with quercetin emerging as a key contributing compound.
Analisis Struktur Kristal Kalsium Hidroksida dari Cangkang Bekicot sebagai Kandidat RAW Material Hidroksiapatit Berbasis Bahan Alam Mujiyanti, Tri; Hariyanto, Yuanita Amalia; Ananingtyas, Ratika Sekar Ajeng
BRILIANT: Jurnal Riset dan Konseptual Vol 6 No 4 (2021): Volume 6 Nomor 4, November 2021
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (580.323 KB) | DOI: 10.28926/briliant.v6i4.811

Abstract

Salah satu bahan alam yang melimpah di Indonesia dan tidak dipergunakan dengan maksimal adalah limbah cangkang bekicot. Penelitian sebelumnya melaporkan bahwa cangkang bekicot memiliki kandungan kalsium oksida sebesar 98,63%, sehingga memiliki potensi yang cukup baik dalam pemanfaatan sebagai biomaterial yaitu hidroksiapatit, dimana diketahui hidroksiapatit ini merupakan salah satu bahan dalam  implan tulang. Penelitian ini bertujuan menganalisis dan mengkarakterisasi kalsium hidroksida sebagai bahan raw material hidroksiapatit dari bahan limbah cangkang bekicot. Cangkang bekicot dikalsinasi untuk menghasikan CaO (Kalsium Oksida) dimana CaO akan berubah fasa menjadi Ca(OH)2 ketika direaksikan dengan air, dengan perlakuan kalsinasi suhu 10000 C dalam waktu 5 jam. Ca(OH)2 (Kalsium Hidroksida) akan di analisis dengan karakterisasi  XRD. Hasil analisis data XRD menggunakan metode scherrer yang menunjukan bahwa Kalsium Hidroksida memiliki rata - rata ukuran partikel sekitar 28 nm. Hasil penelitian menunjukan  bahwa sampel membentuk satu fasa kalsium hidroksida dengan kemurnian tinggi. Analisis rietica sampel Ca(OH)2  menunjukkan bahwa reaksi CaO dan air berhasil membentuk fasa Ca(OH)2 yang ditunjukkan dengan adanya sudut puncak difraksi dimana diperoleh puncak tertinggi pada sudut 2Ө = 34.200 sesuai dengan data model AMCSD code_0000116. Kristal yang terbentuk memiliki sel satuan a,b = 3,59122 Å dan c = 4,904649 Å parameter kisi α = b≠c, α = β = 900, γ= 1200 dengan space group P-3M1.
Karakterisasi Protein Total Konsentrat Daun Kelor (Moringa oleifera Lam) Menggunakan Spektrofotometer UV-VIS Hariyanto, Yuanita Amalia; Azis, Rosidi; Alam, Yuniar; Monica, Anindya Bella
BRILIANT: Jurnal Riset dan Konseptual Vol 7 No 1 (2022): Volume 7 Nomor 1, Februari 2022
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (782.82 KB) | DOI: 10.28926/briliant.v7i1.884

Abstract

Salah satu tumbuhan yang keberadaannya sangat melimpah di Indonesia dengan berbagai macam manfaatnya adalah daun kelor (Moringa oleifera Lam). Daun Moringa oleifera memiliki potensi sebagai bahan feed additives karena tersebar luas di wilayah Indonesia. Di Indonesia para peternak ruminansia sering menggunakan daun Moringa oleifera sebagai imbuhan pakan karena dipercaya dapat menghasilkan daging yang berkualitas tinggi. Penelitian ini bertujuan untuk menganalisis kandungan protein total yang ada dalam daun Moringa oleifera dengan menggunakan metode Bradford. Ekstraksi daun Moringa oleifera lalu di keringkan dengan suhu 30 oC – 35 oC dan di ayak menggunakan ayakan 200 mesh untuk diperoleh serbuk nano. Selanjutnya, disintesis konsentrat protein dengan tambahan akuades dan larutan Bradford untuk di ukur dengan spektrometer pada panjang gelombang ( λ ) 595 nm. Berdasarkan pengukuran menggunakan spektrofometer UV-Vis diperoleh kadar protein total untuk pengujian simplo, duplo, dan triplo sebagai berikut 9,009%, 9,689%, dan 9,495%.
Sintesis dan Karakterisasi Nanokomposit Hidroksiapatit/Tembaga Oksida Sebagai Antibakteri Escherchia coli Hariyanto, Yuanita Amalia; Hakim, M Helmi; Ananingtyas, Ratika Sekar Ajeng; Monica, Anindya Bella
BRILIANT: Jurnal Riset dan Konseptual Vol 7 No 2 (2022): Volume 7 Nomor 2, Mei 2022
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (544.358 KB) | DOI: 10.28926/briliant.v7i2.885

Abstract

Pengolahan limbah cangkang Achatina Fulica yang dimanfaatkan sebagai bahan dasar utama pembuatan hydroxyapatite (HAp). Dalam upaya  menjaga perfomanya, HAp dikompositkan dengan material yang memiliki kemampuan khusus yang sama dan biokompatibilitasnya sangat baik yaitu CuO. Setelah dilakukan komposit material, hasil dari sintesis tersebut dimasukkan ke tahap karakterisasi menggunakan XRD menunjukkan HAp muncul pada = 25,9o; 31,9o; 39,57o; 46,62o, 49,47o. Untuk puncak CuO terdeteksi pada 2-teta = 35,544o, 38,709o, 48,717o, 58,265, dan 61,526o. Selanjutnya, untuk data hasil FTIR menunjukkan terdeteksinya puncak Cu-O berada dalam kisaran 400 hingga 600 cm-1. Untuk puncak Hap terdeteksi gugus fungsi fosfat (PO43) pada kisaran 560, 618, 987, dan 1060 cm-1. Sedangkan fungsi karbonat (CO32-) pada kisaran 910 cm-1 dan 1630-1670 cm-1. Berdasarkan aktivitas antimikroba, pada nanokomposit Hap/CuO menunjukkan kemampuan yang baik dalam membunuh koloni bakteri yang sangat baik.
Peningkatan Nilai Guna Cangkang Kepiting sebagai Kitosan untuk Raw Material pada Pasta Gigi Herbal Hariyanto, Yuanita Amalia; Antasionasti, Irma; Jayanti, Meilani
BRILIANT: Jurnal Riset dan Konseptual Vol 8 No 3 (2023): Volume 8 Nomor 3, Agustus 2023
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28926/briliant.v8i3.1574

Abstract

Sejauh ini inovasi raw material pasta gigi herbal yang berasal dari limbah masih jarang dikembangkan, cangkang kepiting menjadi material yang berpotensi untuk menjadi bahan baku dalam pembuatan pasta gigi herbal. Tujuan penelitian ini yaitu mengembangkan limbah cangkang kepiting menjadi material yang memiliki nilai ekonomi. Penelitian ini dilakukan dengan ekstraksi dan sintesis sederhana. Karakterisasi XRD, FTIR, dan SEM-EDX digunakan untuk menganalisis kristalinitas, gugus fungsi, dan morfologi kitosan. Hasil analisis menunjukkan struktur kitosan membentuk kristalin yang ditunjukkan dengan terkonfirmasinya tiga puncak tajam pada 2-teta 19o, 26o, dan 29o. Hasil analisis puncak serapan FTIR menunjukkan terdeteksinya 5 gugus fungsi utama kitosan pada bilangan gelombang 3458 cm-1, 2895,15 cm-1, 1654,92 cm-1, 1587,42 cm-1, dan 1386,82 cm-1 adalah OH stretching, CH(CH3) bending, C=O (-NHCOCH3) stretching amida I, NH (-NHCOCH3) bending amida II, CH (-CH2) bending sym secara berturut-turut. Morfologi kitosan yang disintesis dari cangkang kepiting berpori, bergelombang, dan bentuknya tidak teratur serta unsur yang terkandung yaitu C, O, Ca, dan Si.
Biosintesis Nanopartikel Hidroksiapatit Termodifikasi Ekstrak Daun Gedi (Abelmoschus manihot L) sebagai Agen Antibakteri Hariyanto, Yuanita Amalia; Jayanti, Meilani; Asari
BRILIANT: Jurnal Riset dan Konseptual Vol 10 No 1 (2025): Volume 10 Nomor 1, Februari 2025
Publisher : Universitas Nahdlatul Ulama Blitar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.28926/briliant.v10i1.2341

Abstract

A tuna bones, particularly in the jaw region, constitute a category of food waste prevalent in North Sulawesi. Hydroxyapatite can be produced from tuna jaws. Abelmoschus manihot L (gedi) can improve the efficacy of hydroxyapatite as an antibacterial agent owing to its bioactive components. This study aimed to assess the antibacterial efficacy of hydroxyapatite treated with Abelmoschus manihot L extract. The samples were produced through multiple stages: preparation of tuna fish bones, synthesis of hydroxyapatite nanoparticles (nHA), extraction of gedi leaves and biosynthesis of nHA from gedi leaf extract. Biosynthesis was conducted via the co-precipitation technique with diverse compositions. The samples were then analyzed using FTIR and TEM, and their antibacterial activity was assessed using the well diffusion method. According to the results of the FTIR study, functional groups from the gedi leaf extract were detected at wave numbers 1731 cm-1, 1234 cm-1, and 896 cm-1, and nHA was discovered at wave numbers 576 cm-1, 608 cm-1, 964 cm-1, and 1041 cm-1, indicating the phosphate group. Furthermore, the results of the TEM investigation revealed that the samples formed spheres smaller than 100 nm. The antibacterial activity of gedi extract/nHA at concentrations of 0.5%, 1%, and 1.5% revealed the presence of inhibitory zones in the strong and very strong categories for S. aureus bacteria. Meanwhile, E. coli bacteria's inhibitory zones were moderate to strong. This suggests that gedi/nHA extract possesses antibacterial properties, making it ideal for use in biomedical applications.
Optimalisasi tumbuh kembang anak usia pra sekolah dalam upaya pencegahan stunting melalui inovasi olahan pangan lokal Yuanita Amalia Hariyanto; Sri Sudewi; Julianri Sari Lebang
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 6 (2025): November
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i6.35210

Abstract

Abstrak Stunting menjadi program prioritas nasional yang membutuhkan perhatian serius, terutama di Kota Manado, Sulawesi Utara. Kota Manado termasuk dalam 8 daerah dengan kasus stunting tertinggi. Stunting dapat menyebabkan hambatan pertumbuhan fisik dan mengancam perkembangan kognitif yang akan berpengaruh pada tingkat kecerdasan saat ini, serta produktivitas anak di masa dewasanya. Anak – anak pra sekolah salah satu kelompok yang beresiko mengalami stunting, hal ini dikarenakan anak-anak yang mudah bosan dengan makanan yang dikonsumsi sehari-hari yang diolah secara monoton. Pengabdian ini bertujuan untuk memberikan penyuluhan tentang stunting dan mengenalkan inovasi olahan pangan lokal yang dapat berfungsi sebagai upaya pencegahan stunting. Kegiatan PKM dilaksanakan di TK. Khalifah dan RA. Raihanah dengan jumlah peserta 35 orang. Metode pelaksanaan kegiatan PKM dilaksanakan dengan 3 tahapan yang meliputi persiapan, pelaksanaan, serta evaluasi dan keberlanjutan program. Tahapan Pelaksanaan kegiatan ini diawali dengan pemeriksaan antropometri, sosialisasi, dan praktik pengembangan motorik anak. Kegiatan terakhir ialah evaluasi, berdasarkan hasil evaluasi peserta mengikuti kegiatan dengan aktif, terdapat 3 anak yang tinggi badannya berada pada kategori -3 SD. Lebih lanjut, hasil survey inovasi olahan pangan 100% peserta menyukai dimsum baik dari aroma, rasa, dan komposisi. Kata kunci: stunting; pra sekolah; olahan pangan lokal. Abstract Stunting is a national priority program that requires serious attention, especially in Manado City, North Sulawesi. Manado City is among the eight areas with the highest number of stunting cases. Stunting can cause physical growth impairment and threaten cognitive development, which may affect children’s intelligence levels and productivity in adulthood. Preschool children are one of the groups at risk of stunting because they tend to get bored with the food they eat daily, which is often prepared in a monotonous way. This program aimed to provide education about stunting and introduce innovations in local food processing as an effort to prevent stunting. The PKM activities were conducted at TK Khalifah and RA Raihanah with a total of 35 participants. The implementation method of the PKM activities consisted of three stages: preparation, implementation, and program evaluation and sustainability. The implementation stage began with anthropometric examinations, socialization, and practical motor development exercises for children. The final stage was evaluation. Based on the evaluation results, participants actively engaged in the activities. Three children were found to have a height in the -3 SD category. Furthermore, the results of the food processing innovation survey showed that 100% of the participants liked the dim sum in terms of aroma, taste, and composition. Keywords: stunting; preschool; local food product.
Co-Authors Abdullah, Surya Sumantri Adikila, Gregorius Giani Adithya Yudistira Aditya Lapu Kalua Aditya Lapu Kalua Aditya Lapu Kalua Agung Sutrisno Ahmad Taufiq Antasionasti, Irma ASARI Asviyatu Nisa' Azis, Rosidi Bakti, Andi Ikhtiar BUKROANAH AMIR MAKKAU DEBY AFRIANI MPILA Della Elshaday Ronga Dian Wahyu Rahmawati Edy Parwanto Elly Juliana Suoth Elly Suoth Ezrani Tasiam Fatimawali . Hakim, M Helmi Herny E.I. Simbala Hidayatun Nasikhah Hosea Jaya Edy Imam Jayanto Imam Jayanto Indah Syaidina Gusti Irma Antasionasti Irma Antasionasti Jayanto, Imam Jesikha Sharen Salikode Juan Sebastian Sirjon Lahope Julianri Sari Lebang Julianri Sari Lebang, Julianri Sari Jumriadi Karlah L. R. Mansauda Karunia Ritje Virginia Rintjap Lestari, Utami Sasmita Lianly Rompis Lisarib, Angelina Mahendra Kusuma Nugraha Meilani Jayanti Monica, Anindya Bella Muhammad Helmi Hakim Muhammad Setiawan Mujiyanti, Tri Najwan Nafis Dzaki Nayla Inayah Abdulgani Pabundu, Daniel Pricillia Esterlita Mintadoa Rama Ijon Turnip Ratika Sekar Ajeng Ananingtyas Regita Reyne Ismail Rizal Musafa Medica Salsabila, Unik Hanifah Saraswati, Indah Ayu Sri Sudewi Sri Sudewi, Sri Sumare, Chika Wanda Sunaryono Tri Mujiyanti TRINA EKAWATI TALLEI Yuniar Alam Yuniar Alam, Yuniar