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All Journal Juke Prosiding SNITP (Seminar Nasional Inovasi Teknologi Penerbangan) Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Media Syari'ah: Wahana Kajian Hukum Islam dan Pranata Sosial JMBA (Jurnal Manajemen dan Bisnis asmi) Jurnal EduHealth Bhakti Nagori (Jurnal Pengabdian kepada Masyarakat) Journal of Islamic and Law Studies (JILS) Medic Nutricia : Jurnal Ilmu Kesehatan Jurnal Pengabdian Masyarakat dan Riset Pendidikan Transformasi Masyarakat : Jurnal Inovasi Sosial dan Pengabdian Al-Mudharabah Jurnal Riset Multidisiplin Edukasi JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Galen: Jurnal Ilmu Farmasi dan Kesehatan
Muhammad Maulana
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Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation Veterinary Other

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Systematic Literature Review: Faktor Risiko yang Mempengaruhi Kejadian Katarak Pada Lansia Kadek Elvina Kusuma Putri; Naila Fathiya Isnanto; Muhammad Maulana; Rani Himayani
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 1 No. 2 (2025): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v1i2.19

Abstract

Katarak adalah opasitas lensa yang menjadi faktor utama yang menyebabkan kebutaan di dunia, termasuk di Indonesia. Menurut data World Health Organization (WHO) tahun 2023, sekitar 18 juta orang menderita kebutaan bilateral akibat katarak, dan di Indonesia 77,7% kasus kebutaan yang disebabkan oleh katarak yang tidak diobati terjadi pada orang berusia >50 tahun. Tinjauan pustaka ini ditujukan untuk menelusuri faktor risiko utama yang berperan dalam kejadian katarak pada lansia, dengan merujuk pada literatur yang diterbitkan di berbagai jurnal ilmiah, baik nasional maupun internasional antara tahun 2018–2025. Analisis terhadap 10 literatur menunjukkan bahwa usia lanjut, jenis kelamin, pekerjaan, diabetes, dan hipertensi adalah faktor utama yang mempengaruhi kejadian katarak. Selain itu, trauma mata dan kebiasaan merokok sebagai faktor sekunder mempercepat perkembangan penyakit.
Meningkatkan Potensi Diri Menjadi Pemimpin Muda Yang Inspiratif Siswa SMA Negeri 1 Cabangbungin Sarmin, Sarmin; Soedjatmoko, Soedjatmoko; Ririn Uke Saraswati; Ranuyoga Asryandi; Andrie Alamin; Muhammad Harun Ma’rifatullah6; Khoirunisa, Khoirunisa; Naidi Wizaya; Muhammad Maulana
Transformasi Masyarakat : Jurnal Inovasi Sosial dan Pengabdian Vol. 2 No. 3 (2025): Juli: Transformasi Masyarakat : Jurnal Inovasi Sosial dan Pengabdian
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/transformasi.v2i3.1956

Abstract

The Community Service (PKM) activity with the theme "Improving Self-Potential to Become an Inspiring Young Leader" is one of the implementations of the Tridharma of Higher Education program implemented by STIE Ekadharma Indonesia. The main objective of this activity is to provide a real contribution to the community, especially students, in efforts to develop self-potential and leadership from an early age. This activity targets grade XII IPS 4 students at SMA Negeri 1 Cabangbungin with a total of 33 participants. In this activity, participants are given a deep understanding of the importance of recognizing and developing their potential, including abilities, talents, interests, creativity, and superior character that can be the foundation for becoming an inspiring and competitive young leader. The material presented in the seminar is designed to equip participants with applicable strategies and insights, such as how to recognize their strengths, build self-confidence, and improve communication and leadership skills. The material delivery process is carried out interactively to encourage active student participation and create a fun and meaningful learning atmosphere. This activity also reflects the spirit of collaboration between higher education institutions and schools in preparing young people who are ready to face future challenges. Evaluation results indicate that this activity was highly effective, demonstrated by the high level of participant enthusiasm, a strong understanding of the material presented, and a positive response to the speakers. This activity is expected to inspire and motivate young people to continue developing themselves and making positive contributions, both within the school environment, on campus, and in the wider community.
Pelatihan Penerapan Harga Pokok Penjualan (HPP) Produk UMKM Pada Dusun Putak Loa Duri Ilir Kecamatan Loa Janan Kabupaten Kutai Karta Negara: Pengabdian Sukirma; Akhmad Al Aidhi; Catur Kumala Dewi; Faizal Reza; Muhammad Maulana; Nurfitriani; Imam Nazarudin Latif; Andi Indrawati; Sunarto
Jurnal Pengabdian Masyarakat dan Riset Pendidikan Vol. 4 No. 1 (2025): Jurnal Pengabdian Masyarakat dan Riset Pendidikan Volume 4 Nomor 1 (Juli 2025 -
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jerkin.v4i1.2297

Abstract

Training on the application of Cost of Goods Sold (COGS) calculation was conducted in Dusun Putak Loa Duri Ilir, Loa Janan District, Kutai Kartanegara Regency, to improve the understanding of micro, small, and medium enterprises (MSMEs) and the tourism awareness group (Pokdarwis) in setting accurate and competitive product selling prices. This activity employed a participatory training method covering material on calculating raw material costs, indirect costs, and determining selling prices based on the desired profit margin. Participants gained insights into the importance of COGS in preventing business losses, estimating profits, and remaining competitive in the market. The results indicated an increase in participants’ ability to calculate COGS in detail and set selling prices aligned with production costs. This training is expected to serve as a foundation for sustainable business development and enhance the competitiveness of local products in the market.
Perbandingan Efikasi Kortikosteroid Topikal dengan Siklosporin A Topikal dalam Pengobatan Dry Eye pada Sindrom Sjögren Maretta, Alvina Christy; Ruth Leria Noverika; Rani Himayani; Muhammad Maulana; Intan Kusumaningtyas; Maureen Angelica
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 12 No 1 (2025): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol. 12.1 (2025)
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v12i1.833

Abstract

Pendahuluan: Sjögren's syndrome merupakan penyakit autoimun sistemik kronis yang menyerang kelenjar eksokrin, terutama kelenjar air mata dan saliva, sehingga menyebabkan dry eye (keratoconjunctivitis sicca) dan mulut kering (xerostomia). Gejala mata kering dialami oleh sebagian besar penderita Sjögren dan dapat berdampak signifikan terhadap kualitas hidup. Salah satu tantangan utama dalam penanganannya adalah memilih terapi topikal antiinflamasi yang efektif dan aman. Dua terapi yang umum digunakan adalah kortikosteroid topikal dan siklosporin A topikal, namun efektivitas dan tolerabilitas keduanya masih menjadi perdebatan. Oleh karena itu, tinjauan ini bertujuan untuk membahas efektivitas, keamanan, dan tolerabilitas kedua agen tersebut dalam mengatasi dry eye pada pasien Sjögren’s syndrome. Metode: Tinjauan literatur ini menggunakan pendekatan naratif yang diperoleh dari database PubMed, Scopus, dan Google Scholar untuk publikasi tahun 2015–2025. Kriteria inklusi mencakup artikel berbahasa Inggris atau Indonesia yang meneliti penggunaan salah satu atau kedua terapi tersebut pada DE akibat Sjögren. Artikel mengenai DE non-autoimun atau terapi sistemik tanpa fokus topikal dikecualikan. Literatur yang relevan dianalisis secara kualitatif untuk menilai efektivitas dan keterbatasan masing-masing terapi. Pembahasan: Berbagai penelitian menunjukkan bahwa penggunaan kortikosteroid topikal dan siklosporin A topikal memiliki efektivitas berbeda dalam penanganan dry eye pada pasien dengan sindrom Sjögren. Kortikosteroid seperti fluorometholone dan loteprednol terbukti memberikan perbaikan gejala yang lebih cepat terutama pada fase akut peradangan, namun penggunaannya dibatasi oleh risiko efek samping jangka panjang seperti peningkatan tekanan intraokular dan risiko katarak. Di sisi lain, siklosporin A menunjukkan keunggulan dalam menurunkan aktivitas inflamasi secara bertahap, aman untuk terapi jangka panjang, dan efektif dalam mengurangi infiltrasi sel imun seperti sel dendritik di permukaan kornea. Beberapa studi juga mendukung bahwa kombinasi kortikosteroid dan siklosporin A dapat memberikan efek sinergis, mempercepat perbaikan gejala tanpa mengorbankan keamanan jangka panjang. Dengan demikian, pemilihan terapi perlu disesuaikan dengan fase penyakit, tingkat keparahan gejala, serta pertimbangan risiko dan manfaat dari masing-masing agen. Simpulan: Kortikosteroid topikal efektif meredakan gejala cepat pada fase inflamasi akut dry eye sindrom Sjögren, namun hanya dianjurkan untuk penggunaan jangka pendek. Siklosporin A lebih aman untuk terapi jangka panjang karena efek imunomodulasinya. Kombinasi keduanya memberikan hasil sinergis. Pemilihan terapi sebaiknya disesuaikan dengan fase penyakit dan profil risiko pasien.
The Effect of Polypharmacy on Drug Interactions in Rheumatoid Arthritis Patients: A Literature Review Vania Putri Risyhade; Asep Sukohar; Muhammad Maulana; Rasmi Zakiah Oktarlina
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rheumatoid arthritis is a chronic autoimmune disease that is progressive in nature and requires long-term therapy involving a combination of multiple drugs. The complexity of treatment increases the risk of polypharmacy, which in turn can trigger drug interactions and reduce the safety and effectiveness of therapy. This literature review aims to describe the relationship between polypharmacy and the potential for drug interactions in patients with rheumatoid arthritis, while considering the importance of monitoring drug use in clinical practice. The writing method was carried out by reviewing various national and international studies related to polypharmacy and drug interactions in rheumatoid arthritis patients. The findings indicate that the concurrent use of several medications, particularly combinations of nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and disease-modifying antirheumatic drugs (DMARDs), can lead to moderate to severe interactions that may cause serious adverse effects such as hepatotoxicity, renal impairment, and bleeding. Furthermore, the greater the number of drugs used, the higher the likelihood of harmful effects, both due to pharmacokinetic and pharmacodynamic interactions. This condition highlights the need for healthcare professionals to regularly evaluate prescribed medications, adjust dosages, and educate patients about the safe and rational use of drugs. These efforts are essential to minimize adverse effects, improve treatment adherence, and achieve optimal therapeutic outcomes in patients with rheumatoid arthritis.
Activity Test of 96% Ethanol Extract of Water Guava Leaf (Syzygium aqueum) on LDL and HDL Values with Propylthiouracil Induction in Rats Setianingsih, Siti; Sunarti; Muhammad Maulana
Viva Medika Vol 17 No 2 (2024)
Publisher : Universitas Harapan Bangsa Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/vm.v17i2.1472

Abstract

One of the plants that can be thought to have antihyperlipidemic potential is water guava leaves (Syzygium aqueum) because they contain chemical compounds, one of which is flavonoids. The aim of this research is to determine the activity of 96% ethanol extract of water guava leaves (EEDJA) as an antihyperlipidemic agent. Male Wistar rats were induced using propylthiouracil (PTU) for 2 weeks (14 days). Hyperlipidemic mice were divided into 5 test groups, CMC-Na group, simvastatin group, EEDJA group (100, 200 and 400) mg/BW. The solution was given to mice routinely once a day for 2 weeks (14 days) orally. The results of the study showed that there were differences before and after administration of EEDJA (100, 200 and 400) mg/BW in LDL and HDL levels with a significance value of 0.000 (<0.005). The conclusion from this study is that EEDJA has potential as an antihyperlipidemic agent in male white Wistar rats
Co-Authors AFRIZAL AFRIZAL Agustia Pratiwi Ahmad A Anindito Aisyah A Putri Akhmad Al Aidhi Amalia Febriyanti Andrie Alamin Asep Sukohar Bintang Johan Permana Catur Kumala Dewi Daniel Happy Putra Desy Amalia Faizal Reza Fauziah Rahmi Hardianawati Hardianawati Ida Laila Imam Nazarudin Latif Intan Kusumaningtyas Kadek Elvina Kusuma Putri Kasmanto Rinaldi Khoirunisa, Khoirunisa M. Fahmi Al Amruzi M. Revo Artmando L Maretta, Alvina Christy Maureen Angelica Mochammad Afifuddin Muhammad Akmal Muhammad Harun Ma’rifatullah6 Muhammad Iqbal Mutiara Rengganis AR Muttaqin Muttaqin Naidi Wizaya Naila Fathiya Isnanto Nashwa Faadillah Nasyim Nurfitriani Rani Himayani Ranuyoga Asryandi Rasmi Zakiah Oktarlina Ririn Uke Saraswati Riska Azzahra Rudi Fikus Prihanto Ruth Leria Noverika Sarmin Sarmin Siti Setianingsih Soedjatmoko, Soedjatmoko Sukirma Sunarti SUNARTO Syazili Mustofa Thamara Az Zahra Vania Putri Risyhade Wasito Utomo