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Journal : Chimica et Natura Acta

Stylotella Sp. Acetone Extract from Selayar Island and Its Activity against Breast Cancer Cells MCF-7 Awaluddin Awaluddin; Asriani Ilyas; Firnanelty Firnanelty; Aisyah Aisyah; Andi Nur Fitriani Abubakar; Aisyah Rusdin
Chimica et Natura Acta Vol 10, No 3 (2022)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v10.n3.42979

Abstract

Styletella sp. is a type of sponge in the Halichondriidae family which is rich in secondary metabolite compounds that have various bioactivities that have the potential as drugs in the future, one of which is anticancer. This study aims to determine the types of secondary metabolites found in Stylotella sp. in Selayar Island and to determine the secondary metabolite bioactivity of MCF-7 breast cancer cells. The method used is extraction using acetone, fractionation and purification. The purity test was carried out by testing three eluent systems at TLC, namely chloroform:ethyl acetate (9:1), n-hexane: acetone (8:2), chloroform: acetone (9:1) eluent. Then qualitatively and characterized by FTIR spectrophotometer. The results showed that pure isolates contained alkaloid compounds. The MCF-7 cell activity test showed an IC50 value for acetone extract of 1452.38 g/mL which has potential anticancer activity and an IC50 value for pure isolate acetone extract of 14983.52 g/mL.
TiO2-Activated Carbon Elaeis Guineensis Jacq Composite Degraded COD and BOD at Batua Raya Waterways Rasyid, Firnanelty; Chadijah, Sitti; Windasari, Windasari
Chimica et Natura Acta Vol 12, No 1 (2024)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v12.n1.48959

Abstract

Activated carbon is an important material for purification, adsorbent and catalyst in the chemical industry. This research has been carried out to determine the photocatalytic activity of the modified catalyst and adsorbent TiO2-activated carbon for reduce of COD and BOD of canal water. Carbon composite was successfully synthesized with mixture of two materials that have different physical and chemical properties. Modification TiO2 with porous material was carried out to determine the optimum mass and contact time for reduce COD and BOD in waterways using photocatalysis method. Activated carbon have made from oil palm bunches through the carbonization process. The composite was tested the optimum TiO2-activated carbon with a ratio of 2:0.4 g which was applied into canal water for 60 minutes. The result showed that COD value was 99.65% and BOD 94.44%. The result of SEM data image showed that activated carbon blocked TiO2 clotting and spread on activated carbon. So that TiO2-activated carbon composite can be used to reduce of COD and BOD level in waterways