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Journal : Jurnal Neuroanestesi Indonesia

Korelasi antara Stroke dengan Covid-19 Bisri, Dewi Yulianti; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 10, No 2 (2021)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1800.035 KB) | DOI: 10.24244/jni.v10i2.356

Abstract

Spektrum klinis covid-19 sangat luas, mulai dari gejala minor yang tidak spesifik, seperti demam, batuk kering dan diare, kadang-kadang dikombinasikan dengan pneumonia ringan dan dispnea ringan, hingga pneumonia berat dengan dispnea, takipnea, dan gangguan pertukaran oksigen, menyebabkan disfungsi paru berat, memerlukan ventilasi mekanik, terjadi syok atau kegagalan organ multipel. Bukti awal yang tidak dipublikasikan menunjukkan bahwa pada pasien dengan covid-19 positip terjadi peningkatan risiko stroke iskemik akut. Keluhan neurologik yang sering terjadi adalah sakit kepala, pusing, perubahan pengecapan dan penciuman, lima persen memiliki risiko terjadinya stroke iskemik akut. Coronavirus mempunyai kecenderungan untuk menginvasi susunan sarap pusat (SSP). Perubahan penciuman yang telah dilihat pada covid-19, diposulatkan karena refleks akses dari virus ke otak melalui rute transcribial, walaupun masih perlu dibuktikan untuk severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Satu laporan dari Cina menunjukkan bahwa keluhan neurologis seperti dizziness, sakit kepala, hypogeusia dan hyposmia, sering terjadi (sekitar 36%) pada pasien covid-19. Ensefalopati dan perubahan status mental juga terjadi pada pasien yang telah terinfeksi dengan virus SARS-CoV-2. Penyakit serebrovaskuler lebih sering pada covid-19 yang berat; stroke iskemik akut telah dilaporkan terjadi pada 5,7% pasien dan gangguan kesadaran pada 15% pasien, dan 1% kejadian perdarahan serebral. Kelainan SSP yang memerlukan tindakan pembedahan memerlukan penanganan khusus karena efek teknik dan obat anestesi terhadap SSP, serta perlindungan tenaga kesehatan untuk mencegah transmisi penyakit. Tigapuluh delapan persen pasien covid-19 dengan komplikasi serebrovaskuler meninggal.Correlation between Stroke and Covid-19AbstractThe clinical spectrum of Covid-19 is very broad, ranging from minor no specific symptom, such as fever, dry cough and diarrhea, some time combined with mild pneumonia and mild dyspnoe to severe pneumonia with dyspnoe, tachypnoe and exchange disorders, leading to severe pulmonary dysfunction, necessary ventilation, shock and multiple organ failure. Preliminary unpublished evidence suggest that patient with covid-19 have an increased risk of acute ischemic stroke. Neurologic complaints that oven occurs are headache, dizziness, change in taste and smell. Five percent risk of developing acute ischemic stroke. Coronavirus has a tendency to invade the central nerve system (CNS). The olfactory change that have been seen in covid-19, are attributed to reflex access from the virus to the brain via the transcribial route, although this remain to be proven for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One report from China showed that neurological complaint, such as dizziness, headaches, hypgeusia and hyposmia, were common (about 36%) in covid-19 patients. Encephalopathy and altered mental status also occurs in patients who have been infected with the SARS-CoV-2 virus. Cerebrovascular disease is more common in severe covid-19; acute ischemic stroke has been reported to occurs in 5.7% of patients and impaired consciousness in 15% of patients, and 1% cerebral hemorrhage was found. CNS disorders that require surgery require special treatment because of the effect of techniques and anesthetics on the CNS, as wll as the protection of health professionals to preventdiseses transmission. Thirty-eight percents of covid-19 patient with cerebrovascular complication died.
Penggunaan Obat Anti Epilepsi untuk Terapi Profilaksis Bangkitan pada Cedera Otak Traumatik Ruslami, Rovina; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 5, No 1 (2016)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3260.66 KB) | DOI: 10.24244/jni.vol5i1.60

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Cedera otak traumatik (COT) merupakan salah satu penyebab bangkitan dan epilepsi. Bangkitan pasca COT (post traumatic seizure/PTS) didefinisikan sebagai bangkitan dini (early PTS) jika terjadi dalam 7 hari pasca COT, atau sebagai bangkitan lanjut (late PTS) bila terjadi sesudah 7 hari pasca COT. Sampai saat ini tidak cukup data yang mendukung rekomendasi level I untuk terapi profilaksis PTS. Kejadian early PTS tidak berhubungan dengan luaran terapi yang lebih buruk. Namun karena insidensinya cukup tinggi, terapi profilaksis dapat menurunkan insidensi early PTS, dan sebagian epilepsi berhubungan dengan cedera kepala sebelumnya, maka terapi profilaksis dapat dipertimbangkan. Terapi profilaksis diindikasikan hanya untuk mencegah early PTS pada kasus COT berat (GCS 8). Terapi profilaksis tidak direkomendasikan untuk mencegah late PTS karena belum ada bukti yang mendukung. Fenitoin (phenytoin=PHT) merupakan obat yang paling banyak diteliti dan digunakan untuk mencegah early PTS, diberikan segera selama 1 minggu. PHT memiliki profil farmakokinetik yang rumit, berbagai efek samping yang memerlukan pemantauan klinis yang ketat dan pemeriksaan kadar obat dalam darah. Obat anti epilepsi (OAE) lain seperti valproat, karbamazepin, dan fenobarbital masih sangat terbatas datanya, memiliki isu keamanan dan farmakokinetik, sehingga saat ini tidak direkomendasikan untuk terapi profilaksis bangkitan pada COT. Levetiracetam (LEV) merupakan OAE yang lebih baru dengan profil farmakokinetik yang lebih bersahabat, namun data terkait efikasi dan keamanan masih terbatas. Diperlukan studi lebih lanjut untuk memperlihatkan jika LEV dapat menggantikan PHT dalam terapi profilaksis bangkitan pasca COT.The Use of Antiepileptic Drugs for Posttraumatic Seizure Prophylaxis after Traumatic Brain Injury?Traumatic brain injury (TBI) is one of the cause of seizure and epilepy. Post traumatic seizure (PTS) is classified as early PTS if occurs within 7 days after injury, and as late PTS if occurs after 7 days following injury. The incidence of PTS is rather high, and seizure prophylaxis could decrease the incidence of early PTS. Furthermore, part of epilepsy are thought to be the result of previous head trauma. Therefore, prophylaxis therapy can be considered. Currently, there are insufficient data to support a Level I reccomendation for seizure prophylaxis after TBI. Early PTS is not associated with worse outcome. It is only indicated for preveting early PST in severe TBI (GCS 8), and not recommended for preventing late PTS due to lack of evidence to support it. Phenytoin (PHT) has been extensively studied and used for prophylaxis of PTS; it is administered during the first seven days after TBI. PHT has numoerus side effects and drug interactions, has complex non-linear pharmacokinetics that require therapeutic drug monitoring. Data from other AEDs like valproate, carbamazepine, and phenobarbital are very limited. They also have sevral safety and pharmackinetics issues. Therefore they are not recommended for preventing PTS. Levetiracetam (LEV) is a newer AED with a more friedly characteristics. However the data regarding the efficacy and safety is limited. Further investigations is needed to evaluate if LEV is a reasonable alternative to PHT for preventing PTS in patients with TBI.
Strategi untuk Mencegah Aspirasi Isi Lambung pada Operasi Cedera Otak Otak Traumatika Emergensi Bisri, Dewi Yulianti; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 1, No 1 (2012)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (361.142 KB) | DOI: 10.24244/jni.vol1i1.82

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Pengelolaan pasien emergensi memiliki tantangan tersendiri bagi anestesiologis. Resiko terjadinya aspirasi isi lambung sangat besar pada pasien emergensi. Angka kejadian aspirasi isi lambung pada pasien emergensi berkisar antara 0,7-4% yang dapat berakibat kematian. Disfungsi gastrointestinal sering terjadi pada pasien dengan cedera otak traumatika. Lebih dari 50% pasien dengan cedera kepala berat tidak mentoleransi enteral feeding. Intoleransi ini manifest dengan adanya muntah, distensi abdominal, pelambatan pengosongan lambung, refluks oesofageal dan penurunan peristaltik intestinal, yang menunjukkan bahwa disfungsi gastrointestinal adalah fenomena yang umum setelah cedera otak traumatika. Puasa merupakan pencegahan yang efektif untuk mengurangi terjadinya resiko aspirasi isi lambung, namun pada kasus emergensi sulit untuk dilaksanakan. Berbagai upaya yang dapat dilakukan pada pasien emergensi untuk mengurangi angka kejadian aspirasi adalah: a) pemberian obat-obatan tertentu sebelum dilakukannya anestesi: histamine 2-reseptor antagonis (ranitidine, cimetidine), proton pump inhibitor (omeprazole), antacid (sodium citrate, magnesium trisilicate) dan antiemetic (ondansentrone), b) posisi kepala yang lebih tinggi dari tubuh 30-45o, c) rapid sequence induction dengan sellick maneuver, d) pemasangan pipa naso atau orogastric dan aspirasi isi lambung. Rapid sequence induction tidak memberi kesempatan untuk mencegah kenaikan tekanan darah saat laringoskopi dan intubasi, padahal untuk pasien dengan kelainan serebral termasuk cedera otak traumatika, harus dihindari lonjakan tekanan darah yang akan meningkatkan tekanan intrakranial. Aspirasi isi lambung merupakan komplikasi anestesi yang mungkin terjadi pada periode perioperatif khususnya pada pasien emergensi. Pengelolaan yang adekuat mampu untuk mengurangi terjadinya resiko aspirasi.Strategy to Prevent Gastric Content Aspiration in Emergency Traumatic Brain Injury SurgeryManagement of an emergency patients has a particular challenge for an anesthesiologist. The risk of pulmonary aspiration from gastric content is very high in emergency cases. The incidence of gastric aspiration in emergency cases is approximately 0.7-4% which could lead to death. Gastrointestinal dysfunction frequently occurs in patients with traumatic brain injury (TBI). More than 50% patients with severe head injuries could not tolerate enteral feedings. This intolerance is manifested by vomiting, abdominal distention, delayed gastric emptying, esophageal reflux and decreased intestinal peristalsis, indicating that gastrointestinal dysfunction is a common phenomenon following TBI. Fasting is an effective manouver to reduce the incidence of gastric aspiration, but in emergency cases is rather difficult to establish that manouver. Several manouvers to reduce aspiration incidence are: a) to administer drugs prior to induction: histamine 2-reseptor antagonist (ranitidine, cimetidine), proton pump inhibitor (omeprazole), antacid (sodium citrate, magnesium trisilicate) and antiemetic (ondansentrone), b) head up position of 30-45o, c) rapid sequence induction with sellick manouver, d) insert naso or orogastric tube and aspirate gastric content. By using rapid sequence induction there would be not enough time to avoid the increase in blood pressure during laryngoscopy-intubation, whereas for patient with cerebral disorder including traumatic brain injury, increased blood pressure should be avoided because this will lead to increase intracranial pressure. Gastric content aspiration is one of anesthesia complication during perioperative periode especially in emergency cases. Adequate managment can reduce the incidency of aspiration.
Hubungan antara Volume Residu Gaster dan Skor Glasgow Coma Scale (GCS) pada Pasien Cedera Otak Traumatik Sedang dan Berat Giovanni, Cindy; Bisri, Dewi Yulianti; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 7, No 1 (2018)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (233.585 KB) | DOI: 10.24244/jni.vol7i1.27

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Latar Belakang dan Tujuan: Cedera Otak Traumatik (COT) berhubungan dengan disfungsi gastrointestinal berupa perlambatan pengosongan lambung. Belum jelas adakah hubungan antara skor Glasgow Coma Scale (GCS) dan derajat gangguan pengosongan lambung yang terjadi. Penelitian ini bertujuan untuk membandingkan volume residu gaster pada pasien COT sedang dan berat serta mengkaji hubungan antara skor GCS dan volume residu gaster pada pasien COT.Subjek dan Metode: Penelitian observasional analitik cross-sectional ini dilakukan pada 42 pasien COT sedang dan berat yang dirawat di RSUP Dr. Hasan Sadikin dari bulan Desember 2016 hingga Juni 2017. Pengukuran volume residu gaster, skor GCS, dan tanda vital dilakukan tiap 6 jam selama 48 jam. Data hasil penelitian diuji dengan uji t tidak berpasangan, Chi Square, dan uji korelasi Pearson. Hasil: Hasil penelitian menyatakan bahwa rerata volume residu gaster pada kelompok COT sedang dan berat adalah 10,83 8,15 ml dan 50,59 18,23 ml (p 0,000). Korelasi antara skor GCS dan volume residu gaster menunjukkan adanya korelasi negatif yang bermakna dan sangat kuat (r=-0,745 hingga -,974;p=0,000).Simpulan: Volume residu gaster pada COT berat lebih banyak dari COT sedang dan terdapat hubungan antara skor GCS dan volume residu gaster pada pasien COT.Correlation between Gastric Residual Volume and Glasgow Coma Scale (GCS) Score in Patient with Moderate and Severe Traumatic Brain InjuryBackground and Objective: Traumatic Brain Injury (TBI) is associated with gastrointestinal dysfunction in the form of delayed gastric emptying. It is not clear whether there is a relationship between Glasgow Coma Scale (GCS) score and the degree of gastric emptying that occurs. This study aimed to compare gastric residual volume in moderate and severe TBI patients and to examine the relationship between GCS score and gastric residual volume in TBI patients.Subject and Methods: This cross-sectional analytical observational study was conducted on 42 moderate and severe TBI patients who were admitted to Dr. Hasan Sadikin from December 2016 to June 2017. Measurement of gastric residual volume, GCS score, and vital signs were performed every 6 hours for 48 hours. The result data were tested with unpaired t-test, Chi Square, and Pearson correlation test. Results: The results showed that the mean gastric residual volume in moderate and severe TBI groups was 10.83 8.15 ml and 50.59 18.23 ml (p 0.000). The correlation between GCS and gastric residual volume showed a very strong negative correlation (r=-0,745 to -,974;p=0,000).Conclusion: Gastric residual volume in patient with severe TBI is more than gastric residual volume in moderate TBI and there was a relationship between GCS score and gastric residual volume in TBI patients.
Perbandingan Mannitol 20%, NaCl 3% dan Natrium Laktat Hipertonik terhadap Osmolaritas dan Brain Relaxation Score Pasien Tumor Otak yang menjalani Kraniotomi Pengangkatan Tumor Wirawijaya, Dear Mohtar; Sitanggang, Ruli Herman; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 7, No 1 (2018)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (244.87 KB) | DOI: 10.24244/jni.vol7i1.15

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Latar Belakang dan Tujuan: Mannitol membuat relaksasi otak, namun memiliki efek samping berkurangnya volume intravaskuler, peningkatan kembali tekanan intrakranial (rebound) dan gagal ginjal. Penggunaan NaCl 3% dan natrium laktat hipertonik dapat memberikan relaksasi otak yang baik. Tujuan penelitian ini untuk mengetahui peningkatan osmolaritas dan brain relaxation score (BRS) pada pasien yang menjalani kraniotomi pengangkatan tumor dengan menggunakan mannitol 20%, NaCl 3%, dan matrium laktat hipertonik.Subjek dan Metode: Penelitian merupakan uji klinik terkontrol secara acak terhadap 39 pasien tumor otak yang masing-masing mendapatkan 2,5cc/kgBB mannitol 20%, NaCl 3%, dan natrium laktat hipertonik. Hasil: Tidak ada perbedaan peningkatan osmolaritas yang signifikan antara ketiga kelompok 1 jam setelah pemberian osmoterapi dan saat durameter dibuka (p0,05). BRS pada ketiga kelompok memiliki nilai median yang sama besar (2,00), artinya tidak ada perbedaan BRS yang bermakna (p0,05). Terdapat peningkatan diuresis yang signifikan pada pemberian mannitol 20%, peningkatan klorida pada NaCl 3% dan peningkatan glukosa signifikan pada natrium laktat hipertonik. Simpulan: Mannitol 20%, NaCl 3%, dan natrium laktat hipertonik memberikan relaksasi otak yang sama dan tidak mengakibatkan perbedaan osmolaritas yang signifikan.Comparison Between 20% Mannitol, 3% NaCl and Hypertonic Sodium Lactate on Osmolarity and Brain Relaxation Score Brain Tumor Patient underwent Craniotomy Tumor RemovalBackground and Objective: Mannitol produce brain relaxation but associated with several side effects such as reduced intravascular volume, rebound in intracranial pressure and kidney failure. The use of 3% NaCl and hypertonic sodium lactate (HSL) may provide brain relaxation. Aim of this study is to examine increased osmolarity and brain relaxation score (BRS) in patient underwent craniotomy using 20% mannitol, 3% NaCl, and hypertonic sodium lactate.Subject and Method: This is a randomized control study of 39 brain tumor patients divided into three groups each obtained 2.5cc/kg 20% mannitol, 3% NaCl, and HSL. Result: there is no significant difference of osmolarity between the three groups 1 hour after administration of osmotherapy and during the opening of durameter (p0,05). BRS between the three groups have an equivalent median score (2,00), it means no significant difference in BRS (p0,05). A significantly increased diuresis in the administration of 20% mannitol, increased chloride to 3% NaCl and significant glucose increase in HSL. Conclusion: Administration of 20% mannitol, 3% NaCl and HSL produce the same brain relaxation and resulted in insignificant osmolarity differences.
Korelasi Skor Glasgow Coma Scale (GCS) pada Cedera Otak Traumatik Berat dengan Kejadian dan Derajat Acute Respiratory Distress Syndrome (ARDS) Junaidi, Agus; Suwarman, S; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 5, No 2 (2016)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2108.356 KB) | DOI: 10.24244/jni.vol5i2.65

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Acute respiratory distress syndrome (ARDS) merupakan salah satu komplikasi dari cedera otak traumatik (COT) berat, dapat disebabkan karena neurogenic pulmonary edema (NPE), pneumonia, aspirasi, dan emboli paru. Penelitian ini untuk mengetahui korelasi skor GCS pada cedera otak traumatik berat dengan kejadian dan derajat ARDS. Penelitian observasional prospektif cross sectional pada 32 orang pasien COT derajat berat di rumah sakit Dr. Hasan Sadikin Bandung sejak Mei 2015 sampai September 2015. Pengambilan data dilakukan secara consecutive sampling. Parameter yang dicatat dalam penelitian ini antara lain usia, jenis kelamin, berat badan, GCS, rentang waktu, diagnosis, kejadian ARDS, dan derajat ARDS. Analisis korelasi linear dua variabel dihitung berdasarkan analisis korelasi Spearman dan korelasi ETA. Hasil penelitian menunjukkan adanya korelasi antara skor GCS pada COT berat dengan kejadian ARDS dengan kekuatan korelasi searah, moderat, (r=0,402), bermakna (p0.05) dan derajat beratnya ARDS dengan kekuatan korelasi searah, kecil (r=0,389), bermakna (p0,05). Simpulan dari penelitian ini adalah semakin rendah skor GCS pada COT berat maka akan semakin besar kejadian ARDS dan semakin berat derajat ARDS.Correlation Glasgow Coma Scale (GCS) Score on Severe Head Injury with the Insidence and Degree of Acute Respiratory Distress Syndrome (ARDS)Acute respiratory distress syndrome (ARDS) is one of the complications of severe traumatic brain injury (TBI), it can be caused by neurogenic pulmonary edema (NPE), pneumonia, aspiration, and pulmonary embolism. This study was determine the correlation glasgow coma scale score on severe head injury with insidence and degree of acute respiratory distress syndrome. This study was using prospective observational cross-sectional method in 32 patients with severe TBI at Dr. Hasan Sadikin General Hospital Bandung on May 2015 untill September 2015. Data collection was performed by consecutive sampling. Parameters were recorded in this study include age, gender, weight, GCS, time scales, diagnosis, incidence and degrees of ARDS. Linear correlation analysis was calculated based on two variables Spearman correlation analysis and correlation ETA. The results showed a correlation between GCS score on severe COT with the incidence of ARDS with the strength of the correlation moderate (r=0.402), significantly (p0.05), one direction and degrees of ARDS with the strength of the correlation small (r=0.389), significantly (p0.05), one direction. The conclusions of this study is the lower the GCS score on severe COT will lead to greater the incidence and the degree of ARDS.
Perbandingan Osmolaritas, Kadar Natrium dan Klorida Plasma setelah Pemberian NaClRL (3:1) dengan Ringerfundin pada Pasien Tumor Otak Martinus, Fardian; Fuadi, Iwan; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 3, No 1 (2014)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2233.519 KB) | DOI: 10.24244/jni.vol3i1.127

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Latar Belakang dan Tujuan : Kristaloid NaCl 0,9% merupakan cairan dasar yang sering digunakan pada perioperatif pasien tumor otak, namun berpotensi menyebabkan asidosis hiperkloremia sehingga dikombinasikan dengan Ringer Laktat. Ringerfundin, kristaloid yang komposisi elektrolitnya hampir ideal, namun belum banyak penelitiannya dalam kasus bedah saraf. Tujuan penelitian adalah membandingkan pemberian cairan kombinasi NaCl 0,9%: RL (3:1) dengan cairan Ringerfundin pada pasien tumor otak untuk melihat osmolaritas, natrium dan klorida plasma. Subjek dan Metode: Penelitian Randomized Controlled Trial (RCT) pada 36 pasien tumor otak yang menjalani kraniotomi, di Rumah Sakit Hasan Sadikin. Sampel dibagi menjadi kelompok NaCl 0,9%:RL (3:1) dan kelompok Ringerfundin. Dilakukan pemeriksaan natrium, klorida plasma dan osmolaritas plasma sebelum dan setelah pemberian cairan sebanyak 1 liter. Data penelitian dianalisis dengan uji t.Hasil: Analisis statistik menunjukkan tidak terdapat perbedaan yang bermakna kedua kelompok setelah pemberian cairan dalam perhitungan osmolaritas plasma 291,42 vs 290,21 (p=0,63) dan natrium plasma 141,28 vs 141,06 (p=0,82). Terdapat perbedaan yang bermakna kadar klorida kelompok NaCl 0,9%: RL dibandingkan dengan kelompok ringerfundin 106,33 vs 104,39 (p=0,02). Simpulan: Ringerfundin dapat menjadi cairan alternatif dari NaCl 0,9%: RL dengan tidak menyebabkan perubahan pada osmolaritas, peningkatan kadar natrium dan kadar klorida plasma.The Comparison of Osmolarity, Plasma Natrium and Chloride Level After Administering NaCI-RL (3:1) and Ringerfundin in Brain Tumor Patients Undergoing CraniotomyBackground and Objective: One of most commonly used crystalloid for perioperative fluid administration in patients with brain tumor is NaCl 0,9%, and because it has potential to cause hyperchloremic acidosis, its administration usually combined with Ringer Lactate. Ringerfundin is a crystalloid solution which contains electrolyte composition that is considered as the most ideal solution, but has not been frequently used in neurosurgery procedure. The aim of this study is to compare the plasma osmolarity, sodium and chloride levels in brain tumor patient after the administration NaCl 0,9% combined with: RL solution in 3:1 ratio and after ringerfundin administration.Subject and Method: Thirty six patients underwent craniotomy tumor removal were assigned randomly to receive NaCl 0,9%: RL (3:1) or ringerfundin solutions. Sodium and chloride plasma level and calculated plasma osmolarity were recorded at baseline and after one liter of fluid adminisitration. Data were analyzed with by using t-test analysis. Result: Statistic analysis showed no significant differences between the two groups in calculated plasma osmolarity (291,42 vs 290,21; (p=0,63) and sodium plasma level (141,28 vs 141,06; (p=0,82). A significant increased in chloride plasma level after one liter of fluid administration was observed in NaCl 0,9%: RL group compared to ringerfundin group (106,33 vs 104,39 respectively; (p=0,02).Conclusion: Ringerfundin is safe and can be use as an alternative fluid aside the most commonly used fluid combination using NaCl 0,9% and RL solutions, without causing changes in plasma osmolarity, and sodium or chloride plasma level.
Penatalaksanaan Perioperatif Hipofisektomi Transsphenoidal: Pendekatan Endoskopik Endonasal Christanto, Sandhi; Suryono, Bambang; Bisri, Tatang; Saleh, Siti Chasnak
Jurnal Neuroanestesi Indonesia Vol 4, No 1 (2015)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (2694.25 KB) | DOI: 10.24244/jni.vol4i1.101

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Tumor kelenjar hipofisa sering dijumpai dan mewakili kurang lebih 10% dari semua neoplasma otak yang terdiagnosa. Meski tersedia terapi medis, pendekatan pembedahan menjadi lebih sering dilakukan. Pendekatan transsphenoidal endonasal endoskopik dipilih karena memiliki keuntungan untuk mencapai regio sella secara cepat dengan resiko kerusakan otak dan komplikasi pascabedah yang minimal. Pengetahuan dan keahlian dokter anestesi tentang pembedahan endoskopik basis kranii dibutuhkan untuk memenuhi kriteria dalam menyediakan keadaan anestesi yang aman, yang akan memainkan peran penting dalam menghasilkan luaran yang diharapkan. Seorang wanita 25 tahun dibawa ke rumah sakit dengan penurunan kesadaran pasca seksio sesarea. Pada pemeriksaan ditemukan edema otak, dan hidrosephalus yang kemudian dilakukan pintas ventrikuloperitoneal. Pemeriksaan lebih lanjut didapatkan massa kistik suprasellar dan pembedahan hipofisektomi transsphenoidal melalui jalur endonasal endoskopik dipilih sebagai pendekatan surgikal. Pasien dengan kelainan hipofisa serta pendekatan pembedahan endoskopik memberikan tantangan tersendiri bagi dokter anestesi. Peralatan endoskopik berteknologi tinggi, pertimbangan intraoperatif yang berhubungan dengan tehnik ini, membutuhkan pengelolaan anestesi yang baik selama periode perioperatif, sehingga dokter anestesi dapat memberikan anestesi yang aman selama prosedur pembedahan dan memberi kontribusi besar bagi keberhasilan dan kemajuan pembedahan endoskopik basis kranii.Perioperative Management of Transsphenoidal Hypophysectomy: Endoscopic Endonasal ApproachPituitary gland tumor represents 10% of all brain neoplasms. Although medical therapy is available, surgical approach becomes commonly performed. The transsphenoidal via endoscopic endonasal is preferred because it has advantage of rapid access to the sella region with minimal traumatic risk to the brain as well as post-operative complications. The highly advance technology, the position of neurosurgeon when performing the surgery and other intraoperative consideration present a unique challenge which require a thorough understanding and the skill of anesthesia management that is tailored to the needs of safe anesthesia for this technique. A 25 years old woman was admitted to hospital following a decreased in level of conciousness after sectio cesarea and found to have edema cerebri and hydrocephalus. Ventricular peritoneal shunt was performed immediately. Further examination revealed a cystic mass in suprasellar region and transsphenoidal hypophysectomy via endonasal endoscopic route was chosen as surgical approach. Patient with pituitary disease and endoscopic method present challenges to the anesthesiologist. High technology equipment and techniques, as well as other intraoperative considerations mandate the skillfulness of anesthesia management throughout the perioperative periode. Those considerations will ensure the neuroanestesiologist for a safe anesthesia and continue to make contributions to the development of full endoscopic skull base surgery.
Manajemen Anestesi pada Penderita Sindroma Pfeiffer dengan Posisi Sphinx Halimi, Radian Ahmad; Bisri, Dewi Yulianti; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 7, No 3 (2018)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (734.459 KB) | DOI: 10.24244/jni.vol7i3.13

Abstract

Sindroma pfeiffer adalah kelainan genetik autosomal dominan berupa fusi prematur tulang kepala dan tubuh lainnya. Operasi rekonstruksi kraniofasial pada pasien dengan sindrom pfeiffer memberikan tantangan tersendiri bagi ahli anestesi. Pada laporan kasus ini, seorang anak perempuan berusia 18 bulan datang ke rumah sakit Hasan Sadikin Bandung dengan keluhan kelainan bentuk kepala sejak lahir. Kelainan tersebut disertai dengan proptosis mata, hipoplasia maksila bilateral, high arc palate, hipotelorisme dan hidrosefalus, namun tidak terdapat riwayat obstruksi jalan nafas. Pasien direncanakan dilakukan prosedur rekonstruksi kraniofasial dan tarsorhaphy dengan posisi modifikasi prone (posisi sphinx). Permasalahan yang terjadi selama operasi adalah obstruksi vena juguler, perdarahan dan kebocoran cairan serebrospinal pascaoperasi. Operasi berlangsung selama 19 jam. Pascaoperasi pasien dirawat di PICU dan dipindahkan ke ruangan perawatan biasa pada hari ke 4. Penanganan perioperatif pasien dengan sindroma pfeiffer yang akan menjalani prosedur operasi kraniofasial membutuhkan penanganan secara multidisiplin dan dibutuhkan pemahaman yang mendalam mengenai fisiologi, potensi permasalahan intraoperasi, resiko dan komplikasi pascaoperasi untuk mencapai hasil luaran yang baikAnesthesia Management in Patients with Pfeiffer Syndrome with Sphinx PositionPfeiffer syndrome is a dominant autosomal genetic disorder characterized by premature fusion of head and other body bones. Craniofacial reconstruction surgery in patients with Pfeiffer syndrome presents a challenge for an anaesthesiologist. This case report discusses about 18 month old girl came to the Hasan Sadikin hospital in Bandung with complaints of clover head shape from birth. The other abnormalities consist of eye proptosis, bilateral maxilla hypophlasia, high arc palate, hypotelorism and hydrocephalus. There was no history of obstructive sleep apneau (OSA). The patient underwent craniofacial vault reconstruction procedure and a tarrsorhaphy with modified prone position (sphinx position). During the operation, there were problems occured such as jugular venous obstruction, bleeding and postoperative cerebrospinal fluid leakage. The procedure takes 19 hours long, and after the operation, the patient admitted to the PICU and being transferred to the ward on day-4. The perioperative treatment of patients undergoing craniofacial surgery requires a multidisciplinary treatment approach, and deep understanding of the physiology, potential intraoperative problems, risks and postoperative complications to achieve better outcomes.
Pemanjangan Ventilasi Mekanik di Intensive Care Unit (ICU) pada Pasien dengan Tumor Glioma Batang Otak yang menjalani Kraniotomi Pengangkatan Tumor Halimi, Radian Ahmad; Bisri, Tatang
Jurnal Neuroanestesi Indonesia Vol 2, No 3 (2013)
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Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (296.456 KB) | DOI: 10.24244/jni.vol2i3.156

Abstract

Kekerapan glioma batang otak mencapai 1020% dari semua tumor primer sistem saraf pusat dan biasanya terdiagnosa pada usia muda. Pada penanganan perioperatif perlu dipertimbangkan cara pengangkatan tumornya, pemakaian steroid perioperatif, perencanaan ventilasi mekanik pascabedah dan fisioterapi. Seorang anak berumur 11 tahun dengan diagnosa tumor batang otak, mengeluh tidak dapat berdiri, penglihatan ganda, afasia, gangguan menelan. Pasien telah menggunakan kortikosteroid dalam waktu yang lama. Dilakukan operasi pengangkatan massa tumor otak dengan lama operasi 10 jam. Pascabedah terjadi pemanjangan ventilasi mekanik, Ventilator Associated Pneumonia (VAP) pada hari ke-4 dan perdarahan lambung pada hari ke-6 di ICU. Teknik operasi sulit karena tumor berada di daerah yang sangat dekat dengan pusat pernapasan dan hemodinamik. Diperlukan perencanaan yang matang mengenai penilaian kondisi pasien saat preoperatif, pemantauan hemodinamik dan tekanan intrakranial, strategi perlindungan terhadap lambung, perencanaan ventilasi mekanik, penilaian cepat perlunya trakheostomi, pemberian antibiotik untuk meningkatkan keluaran yang lebih baik. Prolonged Mechanical Ventilation on Postcraniotomy Tumor Removal on Brainstem Glioma in the Intensive Care Unit Brain stem glioma makes 1020% of primary central nervous system tumor and is diagnosed primarily in children. In perioperative management, approach of tumor removal, steroid usage, mechanical ventilation planning, good nursing care, and physioterapy, should be considered. The aim of this case report is to discuss complications that may occur with prolonged mechanical ventilation after surgery. An 11-year old boy, diagnosed with brain tumor, was admitted to hospital due to inability to stand, double-vision, aphasia, swallowing disorder, with longterm corticosteroid treatment. He underwent a brain tumor removal surgery. Surgery was conducted within 10 hours. After the surgery, he had prolonged mechanical ventilation in ICU. On the fourth day, he suffered from ventilator associated pneumonia (VAP) and gastrointestinal bleeding on the sixth day care in ICU. Patient presented to hospital with late onset symptoms of his condition. Operation technique was difficult as the tumor is located within close proximity to the breathing and haemodynamic centers. There are necessity for detailed perioperative assessment and planning, hemodynamic and intracranial pressure monitoring, gastric protection strategy, mechanichal ventilation planning, quick assessment of tracheostomy installment need and usage of proper antibiotic for a better outcome.
Co-Authors , Rizki , Suwarman - Irwan, - A. Himendra Wargahadibrata A. Muthalib Nawawi Agus Junaidi Aini, Quratul Akbar, Ieva B Alifahna, Muhammad Rezanda Andie Muhari Barzah, Andie Muhari Ardi Zulfariansyah Arief Kurniawan Bambang Suryono, Bambang Christanto, Sandhi Christanto, Sandhi christiana, monica Dedi Fitri Yadi Dewi Yulianti Bisri Diana C. Lalenoh, Diana C. Diana Lalenoh Erias, Muhammad Erwin Pradian Ezra Oktaliansah Firdaus, Riyadh Firdaus, Riyadh Fithrah, Bona Akhmad Fithrah, Bona Akhmad Fitri Sepviyanti Sumardi Giovanni, Cindy Giovanni, Cindy Hamzah, Hanzah Hermawanto, Agung Hindun Saadah, Hindun Ida Bagus Krisna Jaya Sutawan Ieva B. Akbar Ike Sri Redjeki Indrayani, Ratih Rizki Iwan Abdul Rachman Iwan Fuadi Jasa, Zafrullah Khany Kusuma Harimin, Kusuma Laksono, Buyung Hartiyo Lalenoh, Diana Christine Lalenoh, Diana Christine Limawan, Michaela Arshanty M. Dwi Satriyanto M. Erias Erlangga, M. Erias M. Sofyan Harahap Mariko Gunadi Martinus, Fardian Martinus, Fardian MM Rudi Prihatno, MM Rudi Muh. Rumli Ahmad Muhamad Adli Boesoirie, Muhamad Adli Muhammad Habibi Ningsih, Diana Fitria Ningsih, Diana Fitria Noer Rochmah, Elly Nugraha, Ade Aria Nugraha, Ade Aria Nuryanda, Dian Oetoro, Bambang J. Oetoro, Bambang J. Okatria, Ahmado Pontjosudargo, Fransiska Ambarukmi Priyadi, Hendri Putri, Andika C. Putu Pramana Suarjaya Radian Ahmad Halimi Rahmadsyah, Teuku Rahordjo, Sri Rasman, Marsudi Rasman, Marsudi Reza Widianto Sudjud Rose Mafiana Rovina Ruslami, Rovina Ruby Satria Nugraha Ruli Herman Sitanggang Saleh, Siti Chasnak Saleh, Siti Chasnak Saputra, Tengku Addi Saputra, Tengku Addi SATRIYAS ILYAS Septiani, Gusti Ayu Pitria Soefviana, Stefi Berlian Sri Rahardjo Stella, Angela Subekti, Bambang Eko Subekti, Bambang Eko Suryaningrat, IGB Susanto, Bahtiar Sutanto, Sigit Sutanto, Sigit Suwarman Suwarman, Suwarman Suwarman, S Suwarman, S Syafruddin Gaus Thayeb, Srilina Theresia C. Sipahutar Theresia Monica Rahardjo Uhud, Akhyar Nur Widiastuti, Monika - Wirawijaya, Dear Mohtar Wirawijaya, Dear Mohtar Wirawijaya Wullur, Caroline Wullur, Caroline Yunita Susanto Putri Zaka Anwary, Army