Article Per Year (5 Year)
p-Index From 2021 - 2026
0.61
P-Index
This Author published in this journals
All Journal Universa Medicina The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia Journal Medical Informatics Technology
Khie Chen
Divisi Infeksi Dan Penyakit Tropis, Departemen Ilmu Penyakit Dalam, Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo, Jakarta
Computer Science & IT Dentistry Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Universa Medicina

 1 
Culture-and nonculture-based antibiotics for complicated soft tissue infections are comparable Ronald Irwanto; Suhendro Suhendro; Khie Chen; Murdani Abdullah
Universa Medicina Vol. 32 No. 1 (2013)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2013.v32.20 - 28

Abstract

BACKGROUNDData collected in 2010 from Cipto Mangunkusumo Hospital indicate thatcomplicated skin and soft tissue infections accounted for more than 10% ofcases. Etiological diagnoses are based on the findings on bacterial culture andthus evaluation of the effectiveness of bacterial culture becomes a necessity.The purpose of this study was to evaluate the operational effectiveness ofbacterial culture for etiological diagnosis of complicated skin and soft tissueinfections.METHODSThis was a historical cohort study using secondary data of patients withcomplicated skin and soft tissue infections admitted for hospitalization to CiptoMangunkusumo Hospital, Jakarta from July 2011 to July 2012. The 90 subjectsmeeting the inclusion and exclusion criteria were divided into 2 groups of 45patients each. Group 1 comprised patients who received initial antibiotic therapyaccording to cultural results, while the patients in group 2 received initial antibiotictherapy without reference to cultural results. Successful diagnostic culture wasassessed by the absence of therapeutic failure. Therapeutic failure wasdetermined using 3 parameters that had to be fulfilled, viz. absence of antibioticescalation, repeat operations, and clinical deterioration. The latter parameterwas assessed by clinical judgement of the attending physician.RESULTSAfter controlling for confounding variables (age, severity of infection,comorbidity), there was no statistical difference in therapeutic success betweenculture-based and non-culture based initial antibiotic therapies (OR=0.45,p=0.085).CONCLUSIONThis study demonstrates the ineffectiveness of bacterial culture as a diagnosticcriterion for appropriate antibiotic therapy of complicated skin and soft tissueinfections.
Co-Authors A.A. Ketut Agung Cahyawan W Adeputri Tanesha Idhayu Adeputri Tanesha Idhayu Adityo Susilo, Adityo Alvina Widhani, Alvina Andree Kurniawan Anis Karuniawati Anna Ariane, Anna Annisa, Firda Ari F Syam Ari Fahrial Syam Artati Murwaningrum, Artati Bramantya Wicaksana C Martin Rumende C Martin Rumende C. Martin Rumende, C. Martin Ceva W. Pitoyo Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cleopas Martin Rumende Cynthia Olivia Maurine Jasirwan Dana Dharaniyadewi Dana Dharaniyadewi, Dana Danasasmita, Gantira Diana Aulia Diana Aulia Diany N Taher Djoko Widodo Djumhana A Edwin Wijaya Edwin Wijaya, Edwin Erni J Nelwan, Erni J Erni Juwita Nelwan, Erni Juwita Erwin Christian Susanto Esthika Dewiasty Esthika Dewiasty, Esthika Evy Yunihastuti Falasiva, Rezyta Firda Annisa Gantira Wijayakusumah Danasasmita Gurmeet Singh Gurmeet Singh Herdiman T Pohan Herdiman T Pohan Herdiman T. Pohan Herikurniawan Herikurniawan Herikurniawan, Herikurniawan Ina Sutanto Timan Inge Sutanto Jasirwan, Chyntia OM Joko Widodo Joyce Bratanata Joyce Bratanata, Joyce Jumhana Atmakusuma Kemal Fariz Kalista, Kemal Fariz Leonard Nainggolan M Usman SM Maksum, Maradewi Maradewi Maksum Marcellus Simadibrata Marcellus Simadibrata Mira Yulianti Mira Yulianti, Mira Mohammad, Nurhidayat Murdani Abdullah Murdani Abdullah Murdani Abdullah Murdani Abdullah Muzellina, Virly Nanda Nata Pratama Nathanael, Jason Nully Juariah M Pasaribu, Adeline Prima Yuriandro Pringgodigdo Nugroho, Pringgodigdo Resti Mulya Sari Retno Wahyuningsih Retno Wahyuningsih Rezyta Falasiva Robert Sinto Robert Sinto Robert Sinto Ronald Irwanto Rumondor, Bayu B Shakinah, Sharifah Sitorus, Truly Panca Soroy Lardo Suhendro Suhendro Suhendro Suhendro Suhendro Suhendro Suhendro Suhendro Suhendro Suwarto Suhendro Suwarto, Suhendro Susanto, Erwin Christian Telly Kamelia Timan, Ina Sutanto Tonny Loho Truely Panca Sitorus Vera Yuwono Wicaksana, Bramantya Widayat Djoko Santoso Widayat Djoko Santoso Widayat Djoko Santoso, Widayat Djoko Wirawan Hambali Wirawan Hambali, Wirawan Wulyo Rajabto