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All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Hemera Zoa JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI Berkala Penelitian Hayati Jurnal Kedokteran Hewan Jurnal Farmasi Indonesia Current Biomedicine Policy Brief Pertanian, Kelautan, dan Biosains Tropika
Okti Nadia Poetri
IPB University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Electrical & Electronics Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Veterinary

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THE POTENTIAL OF ADJUVANT AGAINST PRODUCTION OF ANTISTREPTOCOCCAL IMMUNOGLOBULIN Y (IGY) IN AQUACULTURE Rizkiantino, Rifky; Wibawan, I Wayan Teguh; Pasaribu, Fachriyan Hasmi; Soejoedono, Retno Damajanti; Poetri, Okti Nadia; Arnafia, Wyanda; Sasi, Kris Damar; Reisinta, Dinda
Jurnal Kedokteran Hewan Vol 14, No 3 (2020): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i3.16911

Abstract

This study was conducted to explore the potential of adjuvant for the production of immunoglobulin Y (IgY) as antistreptococcosis in layer chicken with mass production orientation. Enterococcus faecalis which causes streptococcosis in the red tilapia was selected as a candidateantigen. The production of immunoglobulin Y (IgY) was carried out on Isa Brown layer chickens and aged around 20 weeks. Furthermore, thechickens were grouped into four groups (A, B, C, and D groups), each consisting of three chickens based on the type of adjuvant, while twochickens were used as a control group. Each group was treated by giving MONTANIDE ISA 71R VG adjuvant (A), Freund's adjuvant (B), aluminum potassium sulphate adjuvant (KAl(SO4)212H2O) concentration of 50 ppm in pH 7 (C), and only antigens without adjuvant (D). Chickens were kept for 35 days and each week was checked for presence the IgY antigen in the serum and egg yolk. Booster was conducted on 14th and 28th days of maintenance. The results showed that IgY in treatment group A was detected on day 28 in the serum and day 35 in the yolk. Whereas the treatment group B could be detected on day 35 in the serum. However, the IgY was not detected in the serum and yolk in C, D, and control groups until the end of the maintenance. Based on the results, it can be concluded that the appearance of IgY in serum and yolk in a relatively fast time is obtained in the combination of Enterococcus faecalis antigen with the emulsion of water-in-oil adjuvant (SEPPICMONTANIDE ISA 71R VG) compared to the other types of adjuvant that use in this study.
Evaluation of influenza-specific immunoglobulin Y stability in liquid, solid, and cream-based body care formulations Poetri, Okti Nadia; Setyawati, Yusefin Marcelina; Kal Alfin, Zabrino Wahid; Kalsum, Salsabila; Fathurrahman, Fathurrahman; Rong, Chin Xiao; Nugraheni, Indi Amalia; Kuswanti, Andrea Septiandra
Current Biomedicine Vol. 3 No. 2 (2025): July
Publisher : School of Veterinary Medicine and Biomedical Sciences, IPB University, Bogor, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/currbiomed.3.2.98

Abstract

Background Specific immunoglobulin Y (IgY) is widely used in immunotherapy, with expanding applications in body care products. Topically applied influenza-specific antibodies may provide an alternative strategy for preventing respiratory infections. Objective This study aimed to evaluate the stability and biological activity of influenza-specific IgY in various body care products. Methods The biological activity of influenza-specific IgY was evaluated in various body care products at different concentrations. Commercial face mists contained 5% and 10% w/v IgY, face mists and nasal sprays contained 0.5% w/v IgY, lip balm, sunscreen, and hand cream contained 0.1% and 0.25% w/v IgY. The products were stored at room temperature for four weeks, and organoleptic changes were monitored weekly. IgY activity was assessed by enzyme-linked-immunosorbent-assay (ELISA). Results In both face mist products, the aroma gradually became fishy, the color remained stable, and turbidity increased. The biological activity of IgY was still detectable by ELISA at concentrations of 0.5%, 5%, and 10%. In nasal spray, no changes in aroma, color, or turbidity were observed, but IgY activity was not detectable. In lip balm, sunscreen, and hand cream, only slight color changes occurred without any change in aroma, and IgY activity was not detected. Conclusion Influenza-specific IgY retained biological activity in face mist formulations at higher concentrations (≥0.5%) despite observable changes in aroma and turbidity. In contrast, IgY activity was not detected in nasal sprays, lip balm, sunscreen, or hand cream, suggesting that the formulation type and IgY concentration significantly influence its stability and detectability in body-care products.
Intervensi Dampak Penyakit Kaki Dan Mulut Berbasis Biaya Manfaat Chaerul Basri; Etih Sudarnika; Okti Nadia Poetri; Atsmarina Widyadhari; Cut Desna Apriana; R. Dikky Indrawan; Asep Rakhmat; M. Gumilang Pramuwidyatama
Policy Brief Pertanian, Kelautan, dan Biosains Tropika Vol. 5 No. 3 (2023): Policy Brief Pertanian, Kelautan dan Biosains Tropika
Publisher : Direktorat Kajian Strategis dan Reputasi Akademik IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/agro-maritim.0503.719-722

Abstract

Upaya pengendalian dan pemberantasan PMK di Indonesia jika dilaksanakan dengan program vaksinasi dengan kecepatan seperti yang berlangsung saat ini maka akan menyebabkan waktu pemberantasan yang lebih lama dan kerugian ekonomi yang besar. Perbaikan program vaksinasi dengan kecepatan yang ideal selain dapat memperpendek waktu pemberantasan juga akan memberikan dampak keuntungan ekonomi yang sangat besar. Berdasarkan hasil studi ini direkomendasikan agar upaya pengendalian dan pemberantasan PMK di Indonesia sebaiknya program yang dilaksanakan mengacu kepada skenario vaksinasi dengan kecepatan yang ideal. Dalam penyusunan dan pelaksaan program pengendalian di Indonesia dapat menggunakan program pengendalian yang dikembangkan di Filipina sebagai bahan pertimbangan karena sudah terbukti secara efektif berhasil memberantas PMK dari negara kepulauan seperti di Indonesia
Co-Authors Agustin Indrawati Aldo Yanuar Wuriyantara Anindita Sista Widyadhari Anindita Sista Widyadhari Annisa, Syifa Ari Rumekso Asep Rakhmat Atsmarina Widyadhari Cece Sumantri Chaerul Basri Cut Desna Apriana Dilas Pradana Dinda Reisinta Dwi Desmiyeni Putri Dwi Utari Rahmiati Eko Sugeng Pribadi Ekowati Handharyani Etih Sudarnika Fachriyan Hasmi Pasaribu Fachriyan Hasmi Pasaribu Fathurrahman Fathurrahman Ferry Ardiawan Hadri Latif Hanandi, Sharon I Wayan T. Wibawan I wayan Teguh Wibawan Kal Alfin, Zabrino Wahid Kalsum, Salsabila koekoeh santoso Kris Damar Sasi Kurnia Sari Setio Putri Kurnia Sari Setio Putri, Kurnia Sari Setio Kuswanti, Andrea Septiandra La Jumadin La Jumadin M. Gumilang Pramuwidyatama Melani Wahyu Adiningsih Ni Luh Putu Ika Mayasari Novera Nirmalasanti Nugraheni, Indi Amalia Nur Khusni Hidayanto Nurjumaatun Nurjumaatun Putra, Raditya Pradana R. Dikky Indrawan Rahayu WoroWiranti Rahmasari, Ratika Rahmat Setya Adji Reisinta, Dinda Retno D Soejoedono Retno D Soejoedono Retno D. Soejoedono Retno Damajanti Soejoedono Retno Damajanti Soejoedono Retno Damayanti Soejoedono Retno Setyaningsih Rifky Rizkiantino Rizkiantino, Rifky Rong, Chin Xiao Sasi, Kris Damar Setyawati, Yusefin Marcelina sri murtini . Surachmi Setiyaningsih Sutriyo Suwarny Ruhi Trioso Purnawarman Wilbert Wylie Wyanda Arnafia Wyanda Arnafia, Wyanda