Sri Endah Rahayuningsih
Departemen Ilmu Kesehatan Anak, Fakultas Kedokteran, Universitas Padjadjaran, Bandung

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Journal : Paediatrica Indonesiana

Role of multidetector spiral CT scanning for pulmonary embolism confirmation in a child with pulmonary hypertension: a case report Heda Melinda Nataprawira; Sri Endah Rahayuningsih; Nono Sumarna Afandi; Armijn Firman; Tan Siauw Koan
Paediatrica Indonesiana Vol 49 No 1 (2009): January 2009
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (191.806 KB) | DOI: 10.14238/pi49.1.2009.54-8

Abstract

Pulmonary embolism (PE)  is  associated withconsiderable morbidity and mortality. Earlydiagnosis and prompt treatment  is  essential,  1 • 2however PE  is  rarely clinically diagnosed ortreated in children. Most clinically significant  PE  is  notrecognized antemortem. 3  While its diagnosis remainsa challenge  as  the signs and symptoms  can  often benon-specific,  an  accurate diagnosis  is  essential for themanagement  of  this disease. It  is  known  that  a numberof  non-invasive diagnostic tools are available for itsdetection nowadays. 1 • 2 .4  Even though multi-detectorspiral, also called helical,  CT  scanning  is  promisingand has  been  proven to be useful  in  diagnosing thiscondition with high sensitivity  and  specificity, 5  it  isunavailable even  in  referral hospitals  in  Indonesia.The  gold  standard,  pulmonary  angiography,  isconsidered  as  the procedure of choice to diagnose PE,but  unfortunately it  is  invasive. Failure to diagnose PEaccurately and promptly  can  result in excess morbidityand  death  due to pulmonary hypertension (PH) andrecurrent venous thromboembolic events. Conversely,unnecessary  anticoagulation  therapy poses a riskwithout any benefit.2
Optic nerve sheath diameter and severity of central nervous infection Dewi, Anggun Puspita; Lukmanul Hakim, Dzulfikar Djalil; Rahayuningsih, Sri Endah; Risan, Nelly Amalia; Ghrahani, Reni; Adrizain, Riyadi
Paediatrica Indonesiana Vol. 63 No. 5 (2023): September 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.5.2023.411-7

Abstract

Background Central nervous system (CNS) infection affects the brain, and can cause cerebral edema, increased intracranial pressure (ICP), cerebral herniation, and death. Measurement of the optic nerve sheath diameter (ONSD) by ultrasound is a new, non–invasive examination to predict ICP, with high sensitivity and specificity.Objective To analyze for a possible association between ONSD measured by ultrasonographic examination and severity of CNS infection. Methods This cross–sectional study was performed in the Pediatric Department of Hasan Sadikin Hospital, Bandung, West Java. Subjects were chosen by consecutive sampling. We measured ONSD, examined clinical manifestations, as well as performed a cerebrospinal fluid (CSF) study and imaging of CNS infection. Data analysis was done by paired T–test and one–way ANOVA, followed by Tukey test on significant variables. Results Subjects consisted of 32 children with CNS infection. The most common clinical symptoms were fever, decreased consciousness, and nuchal rigidity. Bivariate analysis revealed strong positive associations between ONSD and Glasgow Coma Scale (GCS), increased protein levels in CSF, and type of CNS infection. Conclusion Larger ONSD is significantly associated with lower GCS, increases CSF protein, and particular CNS infections. The ONSD is also associated with meningitis tuberculosis grade III, with a higher mean ONSD of both eyes compares to other CNS infections. Hence, the higher the ONSD, the more severe the degree of CNS infection.
Co-Authors Adrizain, Riyadi Ahmedz Widiasta Amani Sakinah Augiani Anggia Farrah Rizqiamuti Anggraini Alam Anggraini Alam Anggraini Alam Armijn Firman Armijn Firman Armijn Firman Armijn Firman, Armijn Atika Zahria Arisanti Augiani, Amani Sakinah Benny Hasan Purwara Carla Pusparani Cissy Sudjana Prawira Dani Kurnia Dany Hilmanto Dedet Hidayat Dedi Rachmadi Dedi Rachmadi Dewi Marhaeni Diah Herawati Dewi, Anggun Puspita Dida Akhmad Gurnida Dinna Meinardaniawati Djatnika Setiabudi Dwi Prasetyo Dzulfikar Djalil Lukmanul Hakim Eddy Fadlyana Erliana Ulfah Fathiyah Ma’ani Febrianda, Rilda Dwi Hadyana Sukandar Hakim, Dzulfikar Djalil Lukamnul Haruka Hamanoue Heda Melinda Nataprawira Henry Leo Herman Susanto Herry Garna Herry Herman Ina Rosalina Ineu Nopita Irvan Afriandi Islami - Islami Islami Islami, Islami Julistio Djais Keumala Hayati Keumala Hayati Kusumaputri, Aghnia Ghassani Nanan Sekarwana Naomichi Matsumoto Nelly Amalia Risan, Nelly Amalia Nicholas Adrian Nono Sumarna Nono Sumarna Afandi Nurfandi, Wendi Putria Rayani Putria Rayani Apandi Putria Rayani Apandi, Putria Rayani Queen Khoirun Nisa Mairo, Queen Khoirun Rachmat Budi Rahmat Budi Rahmat Budi Kuswiyanto Rahmat Budi Kuswiyanto, Rahmat Budi Reby Kusumajaya Reni Ghrahani Riri Adriana Rizki Ayu Rizal Rossanti, Rini Rully Marsis Amirullah Roesli Shinta Larasaty Sjarif Hidajat Effendi Sri Sudarwati Susiarno, Hadi Syahradian Hasbrima Tan Siauw Koan Thiban Raj Manoraj Tisnasari Hafsah, Tisnasari Tommy Nugrahadi Whisnubrata Tono Djuwantono Tubagus Ferdi Fadilah, Tubagus Ferdi Uni Gamayani Vidi Permatagalih Villia Damayantie Wiwin Winiar Yanti Mulyana Yulia Sofiatin Yunita Sinaga