Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health)

Systematic Review: Impact of Bisphenol-A (BPA) Exposure on Human Health Sulistiyani, Sulistiyani; Okti Iswari Triswindyaningrum; Yusniar Hanani Darundiati
JURNAL KESEHATAN LINGKUNGAN Vol. 17 No. 1 (2025): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v17i1.2025.85-98

Abstract

Introduction: One chemical substance used in producing epoxy resins and polycarbonate (PC) is called bisphenol-A (BPA). Three million tons of the chemical compound bisphenol-A are still produced annually. The amount of BPA produced in 2015 was 7.7 million tons; by 2022, 10.8 million tons are anticipated to be made. This study aimed to ascertain the effects of bisphenol-A exposure on human health. Discussion: This study used a systematic review method by collecting articles through online databases with a publication range of 2018 - 2024. The article search used the PRISMA flow diagram. The findings of 30 articles all examined the impact of BPA exposure on health. The level of exposure to bisphenol-A can have an impact on health due to the nature of BPA EDC (Endocrine Disrupting Hormone) which can inhibit the activity of natural hormones in the body. Conclusion: The impact on human health due to exposure to bisphenol-A such as cancer, obesity, disruption of reproductive health, hypertension, disrupting child development, and also behavioral changes in children. Bisphenol-A enters the body not only through food packaging but also through air and dust contaminated with BPA. The length of exposure and concentration of BPA affect its effects on the human body.
Association Between Pesticide Exposure and Type 2 Diabetes Mellitus Among Female Farmers: A Cross-Sectional Study Masyithah, Wulan; Onny Setiani; Yusniar Hanani Darundiati; Mursid Raharjo; Nurjazuli
JURNAL KESEHATAN LINGKUNGAN Vol. 17 No. 3 (2025): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v17i3.2025.220-229

Abstract

Introduction: The widespread use of pesticides in agriculture has been linked to an increased risk of diabetes mellitus. Long-term exposure to pesticides can disrupt glucose metabolism, trigger insulin resistance, and raise susceptibility to diabetes mellitus. This study investigates the association between pesticide exposure and the incidence of type 2 diabetes mellitus. Methods: This analytical observational study with a cross-sectional design involved 162 female farmers selected by purposive sampling from a population of 2,187, using the Lemeshow formula. Independent variables included work duration, types and frequency of pesticide use, spraying duration and direction, PPE usage, and cholinesterase levels. The dependent variable was type 2 diabetes mellitus. Data were collected through questionnaires, observation, and clinical tests for blood glucose and cholinesterase levels. Logistic regression was performed at 95% CI and α = 0.05. Result and Discussion: The results showed that 69.1% of female farmers exposed to pesticides had diabetes with lower cholinesterase levels as a significant indicator (p<0.001; OR=3.897; 95% CI=2.087-7.277). Factors such as working duration ≥10 years (p=0.010; OR=3.564; 95% CI=1.359-9.346), number of pesticides types (p=0.023; OR=3.370; 95% CI=1.187-9.570), spraying duration (p=0.020; OR=3.083; 95% CI=1.197-7.940), and PPE usage (p=0.007; OR=3.601; 95% CI=1.416-9.159) were associated with type 2 diabetes mellitus. Conclusion: Pesticides, particularly organophosphates and carbamates, act as endocrine-disrupting chemicals that impair pancreatic function and increase oxidative stress, contributing to insulin resistance. Female farmers more vulnerable to these effects due to hormonal sensitivity, making gender specific approaches essential. Strict regulations and farmer education are crucial to reduce long-term health risks.
Co-Authors Abd. Rasyid Syamsuri Ahmad Farid Ali Djamhuri Amalia Jamil Angelina, Maria Sylvia Anggraeni, Siti Hafidzhah Dyah Ayu Anissah, Neli Annisa Amaliana Annisa Rachmawati Apoina Kartini Ardias Ardias Arumsari, Fina Astri Wulandari Ayu Larasati Az Zahro, Putri Rahmawati Az-zahro, Putri Rahmawati Azhari, Achmad Rizki Azhari, Achmad Rizki Azzahra Pratadina Bariyadi Rifai Benedikta Familia Santcawarti Budiyono Budiyono Budiyono Budiyono Cahyo Setiawan Charles foeh Foeh Chesaria Candra Cahyani Chintya Pangestika Choirul Luluk Fatimah Cresti Dwitiya Murti Daramusseng, Andi Diah Ayu Pusparini, Diah Ayu Dian Indriyani Diana Islamawati Eka Wahyuni Fatikha Firdausi Fitria Andriani Fitrisya Lucki Dwiyanti Fransiska Vony Wicheisa Galuh Candra Dewi Hanan Lanang Dangiran Hanan Lanang Dangiran, Hanan Lanang Hapsari, Titi Hari Ismanto Hasim, Jamal Hisham Ika Fitriati, Ika Ilham Pradana Sulistiyono Putra intan permata sari Karunia Dwi HPS Kunti Wijiarti Laila Fitria Lailya Indha Pramastuti Lina Yulianti Linda Devega Masyithah, Wulan Maulida, Devina Alya Maysaroh Nur Istikomah Mayvika Farah Fadhila Munawaroh, Dinni Asmini Mursid Rahardjo Mursid Raharjo Nasution, Lailatussyifah Niki Astorina Yunita Darundiati Niki Astorina Yunita Dewanti Niki Astorina Yunita Dewanti, Niki Astorina Yunita Nikie Astorina Yunita Dewanti Nuha, Nabila Ulin Nur Endah Wahyunigsih Nur Endah Wahyuningsih Nur Latifah, Endah Nurjazuli Nurjazuli Nurjazuli Nurul Qodariyah Oktavia Suci Setyoningsih, Oktavia Suci Okti Iswari Triswindyaningrum Onni Setiani Onny Setiani Onny Setiani Poppi Nastasia Dewi Pudjaningrum Pudjaningrum Puspita, Yashinta Dwi Rahmadayanti Rahmadayanti Rahmah, Syifa Rifqa Ainur Rainy Rifta Raisha Selviastuti Regita Damayanti Saputri Rifka Fuazia Bilqis Risa Kartika Putri Risma Dwi Yulianti Rizka Laila Rachmawati, Rizka Laila Solly Aryza Sri Winarni Suhartono Sukma Dewi Novianti Sulistiyani SULISTIYANI SULISTIYANI Sulistiyono Putra, Ilham Pradana Sulistyani Sulistyani Tika Adelia Nurkholis Puteri Tri Joko Ufairoh, Azum Ulfa, Elok Fadila Utami, Desi Putri Vitasari, Marliana Wahida Inayatun Nikmah Wahyu Sekar Harjanti Widya Kristiani Dory Purba, Widya Kristiani Dory Winnoto Winnoto Yudi Akbar, Faris Yuliani Setyaningsih Zahra, Nabilah