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All Journal Journal of Health (JoH) Medical Laboratory Technology Journal THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat JPM (Jurnal Pemberdayaan Masyarakat) Jurnal Analis Kesehatan Jurnal Kesehatan Medical Technology and Public Health Journal Medica Hospitalia Medicra (Journal of Medical Laboratory Science/Technology) Academia Open Humanism : Jurnal Pengabdian Masyarakat Medical Scope Journal (MSJ) Jurnal Abdimas Kartika Wijayakusuma Indonesian Journal of Innovation Studies Procedia of Social Sciences and Humanities Journal of Noncommunicable Diseases (JOND) Prosiding University Research Colloquium Indonesian Journal Health Science and Medicine Folia Medica Indonesiana
Andika Aliviameita
Universitas Muhammadiyah Sidoarjo
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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POTENTIAL MOLECULES AGAINST COVID-19 FROM ANNONA MURICATA; AN IN-SILICO APPROACH Miftahul Mushlih; Andika Aliviameita; Puspitasari Puspitasari; Ahmad Shobrun Jamil
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 6 No 1 (2022): Medical Technology and Public Health Journal March 2022
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v6i1.3069

Abstract

At the end of 2019, a new virus emerged from Wuhan, China named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The key to viral infection to host cells is the use of the ACE2 receptor. This study aimed to explore the potential of drugs in Annona muricata plant using the Insilico method. Compounds obtained from KNApSAcK Based on the analysis using SwissADME (Lipinski creteria)criteria. 22 compounds passed the selection. Eight ligands were identified as being able to change the conformation of the initial form of RBD and ACE2 attachment. Eight molecules are able to change the initial conformation, namely Asimilobine, Coreximine, (+)-Stepharine, Coclaurine, Norcorydine, N- Nornuciferinhe, methoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolin-5-ol, and Atherosperminine.
Comparison of Erythrocyte Index Values of Venous and Capillary Blood : Perbandingan Nilai Indeks Eritrosit pada Darah Vena dan Kapiler Wahyuni, Nining; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 1 (2021): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i1.895

Abstract

Erythrocyte index is a laboratory examination in establishing the diagnosis of anemia including MCV, MCH, and MCHC obtained from the calculation of hemoglobin, hematocrit, and the number of erythrocytes. This study aims to determine differences in the value of the erythrocyte index in venous and capillary blood. This research is an experimental laboratory study, the sample was examined at the Ar-Rahmah Tulangan Clinic in Sidoarjo in March 2020. The examination method used in this study was automatic. Blood samples were taken from 30 patients so that a total of 60 blood samples (30 venous blood and 30 capillary blood). The results of the examination with the Mann Withney test showed a significant difference in the value of MCV (p = 0.001) and MCH (p = 0.001) and there was no difference in the value of MCHC (p = 0.251).
Relationship Between Transaminase Enzyme Levels And Gamma GT In Diabetes Mellitus Patients With Diabetic Foot Ulcers: Hubungan Kadar Enzim Transaminase Dengan Gamma GT Pada Pasien Diabetes Mellitus Dengan Ulkus Kaki Diabetik Emilia, Hilda; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 4 No. 2 (2021): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v4i2.1461

Abstract

Diabetes Mellitus is a chronic disease when the body cannot use insulin or cannot produce insulin enough, and glucose level in the blood increases. Diabetic ulcers are open sores on the skin surface caused by complications of macroangiophaty which can lead to neurophaty and vascular insufficiency. This study aims to determine the relationship between transaminase enzyme levels and Gamma GT in diabetes mellitus patients with diabetic foot ulcers. The sample used in this study was 30 patients with diabetes mellitus with diabetic foot ulcers. Research samples were obtained at Rumah Luka Sidoarjo and examined in the Hematology Laboratory of the Faculty of Health Sciences Muhammadiyah University in March 2021. SGOT and SGPT examination used the UV Enzymatic method, while the Gamma GT examination used the Enzymatic colorimetric method. In the Correlation-Regression test, it was found that there was no significant relationship (p=0,481) between SGOT Gamma GT, but there was a significant relationship (p=0,037) between SGPT and Gamma GT. Conclusion there is a moderate correlation (r=0,413) between transaminase anzymes and gamma GT in diabetes mellitus patients with diabetic foot ulcers.
Hubungan Profil Lipid Dengan Kadar Glukosa Darah Pada Pasien Diabetes Mellitus: Relationship between Lipid Profile and Blood Glucose Levels in Diabetes Mellitus Patients Puspitasari, Puspitasari; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 1 No. 2 (2018): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v1i2.1831

Abstract

Diabetes mellitus is disease caused by a disorder of glucose metabolism. At present, diabetes mellitus is health problem in the world. Increased blood glucose levels can increase the risk of complications of various organs, one of which is cardiovascular disease. This study aims to determine the relationship between cholesterol total levels and triglycerides with blood glucose levels in patients with diabetes mellitus. This type of research is observational analytic with cross sectional design. A total of 45 samples were selected selectively at Aisyiyah Siti Fatimah Tulangan Hospital in January 2016-February 2018. The results of multiple linear regression analysis showed a statistically significant relationship between total cholesterol levels and blood glucose (b = 0,607; p = 0,046), and triglyceride levels with blood glucose levels (b = -0,276; p = 0,003). Based on the results, we found a stati
Pengaruh Lama Penundaan Pemeriksaan Serum Terhadap Kadar Elektrolit Natrium dan Klorida: The Effect of Delayed Serum Examination on Sodium and Chloride Electrolyte Levels Azizah, Nurul; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 2 No. 1 (2019): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v2i1.2589

Abstract

Electrolytes play an important role in the human body that can affect metabolism. Sample handling more than two hours in examination electrolyte levels would lead to less accurate results. This study aims to determine the effect of long delays serum examination of the levels of electrolytes sodium and chloride for 0, 3, 5, and 7 hours. This research was conducted with an experimental method using 32 serum samples. Results of sodiumand chloride levels after an increase in deferred examination. The mean 0 hour sodium level is 142.55 mmol/L, 3-hour sodium level is 143.18 mmol/L, 5-hour sodium level is 143.91 mmol/L and 7-hour sodium level is 144.41 mmol/L. The mean 0 hour chloride level is 97.66 mmol/L, 3-hour chloride level is 99.96 mmol/L, 5- hour chloride level is 103.62 mmol/L and 7-hour chloride level is 107.55 mmol/L. This study reflected thatthere is no effect of delaying serum on sodium levels, and there is an effect of delaying serum on chloride levels.
The Effect of Variations of Serum Examination Time Lapse on Electrolyte Levels of Potassium and Chloride: Pengaruh Variasi Selang Waktu Pemeriksaan Serum Terhadap Kadar Elektrolit Kalium dan Klorida Asri, Nur Indah Nila; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 5 No. 2 (2022): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v5i2.1639

Abstract

Electrolyte is a chemical substance that dissociates in the liquid into charged particles of positive and negative ions. In the laboratory, conditions are often found that make an examination not immediately carried out after sampling. The purpose of this study was to determine the effect of variations in serum examination time intervals on Potassium and Chloride electrolyte levels for 0, 4, 8 and 24 hours at room temperature (20-25℃). This study used a laboratory experimental method with a sample of 32 samples. This research was conducted at the Bhayangkara Hospital Pusdik Brimob Watukosek Laboratory. Examination of Potassium and Chloride electrolyte levels using the OPTI CCA-TS Analyzer. The results of the One Way Anova test for Potassium electrolyte levels obtained a significance p value of = 0,199 meaning that there was no effect of variations in serum examination time intervals on Potassium electrolyte levels, while Chloride electrolyte levels obtained a significance value of p = 0,002 meaning that there is an effect of variations in serum examination time intervals on Chloride electrolyte levels.
The Effect Of Delay Time And Storage Temperature On The Results Of Urine Leukocyte Examination In Patients Of Urinary Tract Infection (UTI): Pengaruh Lama Waktu Penundaan Dan Suhu Penyimpanan Terhadap Hasil Pemeriksaan Leukosit Urine Pada Pasien Infeksi Saluran Kemih (ISK) Krisdianti, Rika; Puspitasari, Puspitasari; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 1 (2023): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i1.1660

Abstract

Urinary Tract Infection (UTI) is a condition where there are microorganisms that multiply in the urinary tract causing inflammation and bacteriuria. The delay in the examination results in an error in diagnosis, the examination must be carried out >1 hour and a maximum of 2 hours after the voiding process at a temperature of 20-25℃ and the delay can be done a maximum of 4 hours at a temperature of 2-8℃. The study was conducted in June 2022. The study was conducted at SMK Muhammadiyah 1 Pandaan. UTI sampling at Sahabat Hospital in Suwayuwo Sukorejo. The purpose of this study was to determine the effect of delay time and storage temperature on the results of urine leukocyte examination in UTI patients. This study used an experimental method using 35 urine samples. The statistical test used the Two Way Anova test with a 95% confidence level and the inaccuracy limit of (α) = 0.05. Based on the results of the Two Way Anova test between storage temperature and delay in urine leukocytes, a significance value of 0.981 (p>0.05), it can be concluded that Ha is rejected and Ho is accepted, meaning that there is no interaction effect between the length of time delay and storage temperature on leukocyte results. urine in UTI patients.
The Effect Of Serum StorageTime On Room Temperature On Creatinine And Uric Acid: Pengaruh Lama Penyimpanan Serum Pada Suhu Ruang Terhadap Kadar Kreatinin Dan Asam Urat Lestari, Dzulia; Aliviameita, Andika
Medicra (Journal of Medical Laboratory Science/Technology) Vol. 6 No. 2 (2023): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/medicra.v6i2.1675

Abstract

The examination parameters used as a detection of impaired kidney function are ureum, creatinine, and uric acid. The purpose of this study was to determine the effect of serum storage duration at room temperature on creatinine and uric acid levels. The study was conducted by experimental method using 32 serum samples. The data obtained by one wayAnova statistical analysis on creatinine examination showed a significance value of p = 0.009 (p<0.05) meaning that there was an influence of the length of serum storage on creatinine levels at room temperature, while in uric acid levels showed a significance value of p = 0.047 (p<0.05) meaning that there was an influence of serum storage duration on uric acid levels at room temperature. The conclusions on the examination of creatinine and uric acid levels had a significant effect on the delay of the treatment group of 0 hours and 24 hours.
Perbedaan Hasil Pemeriksaan Hemoglobin Antara Metode Point of Care Testing Dengan Metode Sianmethemoglobin Pada Ibu Hamil Puspitasari, Puspitasari; Aliviameita, Andika; Rinata, Evi; Yasmin, Rizka Afifah Yonika; Saidah, Sukma Nur
Jurnal Analis Kesehatan Vol. 9 No. 1 (2020): JURNAL ANALIS KESEHATAN
Publisher : Department of Health Analyst, Politeknik Kesehatan, Kementerian Kesehatan Tanjungkarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (44.73 KB) | DOI: 10.26630/jak.v9i1.2113

Abstract

Pemeriksaan kadar hemoglobin pada ibu hamil merupakan faktor yang penting karena sering ditemukan kondisi kurangnya zat besi selama masa kehamilan. Berbagai metode pemeriksaan hemoglobin digunakan pada fasilitas pelayanan kesehatan. Penelitian ini bertujuan untuk mengetahui perbedaan hasil pemeriksaan hemoglobin antara metode Point of Care Testing (POCT) menggunakan darah kapiler dan darah vena dengan metode sianmethemoglobin menggunakan darah vena pada ibu hamil. Penelitian ini merupakan penelitian eksperimental laboratorium dengan desain studi observasi analitik cross sectional. Penelitian dilakukan di Laboratorium Puskesmas Sukodono Kabupaten Sidoarjo pada Maret - April 2020. Sampel yang digunakan yaitu pasien ibu hamil di Puskesmas Sukodono berumur 15-34 tahun sebanyak 30. Hasil analisis menggunakan uji t tes sampel bebas didapatkan nilai t hitung sebesar 1,543 dengan p- value sebesar 0,128. Hasil analisis menggunakan uji t tes berpasangan didapatkan nilai t hitung sebesar 2,736 dengan p-value sebesar 0,011. Dapat disimpulkan bahwa tidak terdapat perbedaan yang signifikan secara statistik antara rata-rata hasil pemeriksaan hemoglobin metode POCT darah kapiler dengan metode sianmethemoglobin darah vena dan terdapat perbedaan yang signifikan secara statistik antara rata-rata hasil pemeriksaan hemoglobin metode POCT darah vena dengan metode sianmethemoglobin darah vena.
Insilico study of Phyllanthus niruri potency as an antiviral Sars Cov 2: Omicron and delta variants : Analisis Potensi Phyllanthus niruri sebagai antivirus Sars Cov 2: varian Omicron dan delta secara insilico Mushlih , Miftahul; Aliviameita, Andika; Puspitasari; Firmansyah, Nukayo; Murosidah, Pratasya Liyaajul
Procedia of Social Sciences and Humanities Vol. 3 (2022): Proceedings of the 1st SENARA 2022
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pssh.v3i.251

Abstract

Corona Virus Disease 19 (Covid 19) caused by infection with severe acute respiratory syndrome coronavirus 2 (Sars Cov-2). In its development, this virus has several variants due to mutations, including the Omicron (B.1.1.529) and delta (B.1.617.2) variants of concern, one of the keys to infection with this virus is the angiotensin receptor enzyme 2 (ACE-2). This study aimed to explore the potential of Phyllanthus niruri plant insilico. The active plant components were explored from the KNackSAcK family, then selected using Lipinski criteria using SWISS ADME, docking using HEX 8.0. The results of the analysis showed that 5 of the 21 compounds met Lipinski's criteria, i.e Hypophyllanthin, Hinokinin, 4-Methoxynorsecurinine, Nirtetralin, & Lintetralin. Nirtetralin & 4-Methoxynorsecurinine were able to change the binding conformation of RBD-ACE2 in the Omicron variant, while Hinokinin was able to change the binding conformation of RBD-ACE2 in the delta variant. These results were different from the first discovered sars cov 2, in which Hinokinin, 4-Methoxynorsecurinine, & Nirtetralin were able to change the conformation of RBD-ACE2.
Co-Authors Ahmad Shobrun Jamil Ahmad Yudianto Ainutajriani, Ainutajriani Alda Megawati Amilya, Widya Intan Anggie Wedha Puspita ARDIANSYAH, SYAHRUL Arief Wisaksono Ariyanti, Silvia Asri, Nur Indah Nila Aziza, Vidayatul Batis, Afifah Diah Ariana Dian Delta Dina Trikumalasari Dira Nadila Ellies Tunjung Sari Maulidiyanti, Ellies Tunjung Sari Emilia, Hilda Evi Rinata Fadilatin, Lisa Anis Firmansyah, Nukayo Fitrian Desi Prameswari Hadie, Djauharoh A Intantri, Risma Jamilatur Rohmah Krisdianti, Rika Lestari, Dzulia Livia Nur Azzah Meryn Linanda Agustin Mieke Sylvia Miftahul Mushlih Millah, Hamidah Wardatul Murosidah, Pratasya Liyaajul Mushlih , Miftahul Nevy Elensya NURUL AZIZAH p Puspitasari, p Primastuti, Yuridistya Putri Puspita, Anggun Puspitasari Puspitasari Puspitasari Puspitasari Qilmia Fanani Ramadhan, Syahrul Ibnu Mubaroq Riantika, Mayang Rini, Chylen S. Rini, Chylen Setyo Rohman Dijaya Saidah, Sukma Nur Salim, Siti Zaenab Savitra, Igfina El Segara, Bayu Setiyo Rini, Chylen Silvia Ariyanti Siska Aprilia Siti Zaenab Salim Sri Mukhodim Faridah Hanum Wahyuni, Nining Xena, Alfanny Juliannindy Yanik Purwanti Yasmin, Rizka Afifah Yonika Zakaria, Rizal