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All Journal Jurnal Pengolahan Hasil Perikanan Indonesia Jurnal Natur Indonesia Jurnal Perikanan dan Kelautan Jurnal Sains Dasar Jurnal Penelitian Farmasi Indonesia Jurnal Ilmu Perairan (Aquatic Science) JURNAL PETERNAKAN Jurnal Riset Kimia Jurnal Ilmu Farmasi dan Farmasi Klinik (Journal of Pharmaceutical Science and Clinical Pharmacy) Biology, Medicine, & Natural Product Chemistry Medical Laboratory Technology Journal ALCHEMY Jurnal Penelitian Kimia Jurnal Penelitian Farmasi Indonesia Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JOPS (Journal Of Pharmacy and Science) JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PHOTON JURNAL PENDIDIKAN TAMBUSAI JFL : Jurnal Farmasi Lampung TEKNOLOGI PANGAN : Media Informasi dan Komunikasi Ilmiah Teknologi Pertanian Jurnal Kreativitas PKM Jurnal Ilmu Kefarmasian Indonesia Jurnal Dunia Farmasi Acta Chimica Asiana Jurnal Mandala Pengabdian Masyarakat Jurnal Insan Farmasi Indonesia FORTE JOURNAL Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Hasi Penelitian Dan Pengkajian Ilmiah Eksakta - JPPIE Journal of Artificial Intelligence and Digital Business Jurnal Katalisator Jurnal Farmasi Indonesia BATOBO: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Jurnal Garuda Pengabdian Kepada Masyarakat Jurnal Bakti Nusantara Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Perikanan dan Kelautan IPSSJ Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Musyirna Rahmah Nst
Sekolah Tinggi Ilmu Farmasi Riau
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AKTIVITAS ANTIOKSIDAN SEDUHAN DAUN KOPI KAWA KERING (Coffea arabica L) DENGAN METODE DPPH Musyirna Rahmah Nasution; Martina Br Manullang
Jurnal Insan Farmasi Indonesia Vol 3 No 1 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i1.467

Abstract

Kawa Coffee is a traditional beverage made from coffee leaves which is a typical drink in Tanah Datar in West Sumatra. The dried kawa coffee leaves are brewed with hot water to produce a brownish color.Kawa coffee leaves (Coffea robusta L) containsecondary metabolites such as flavonoids. Flavonoids have been known to have antioxidant activity. Research has been conducted to determine antioxidant activity from steeping kawa coffee leaves using the DPPH method by spectrophotometry. The test concentrations used were 5%, 2.5%, 1.25%, 0.625%, 0.313%, 0.156%. The results showed that steeping dried kawa coffee leaves at a concentration of 5% had given DPPH radical inhibition of 87.036%. The IC50 obtained is 0.591%. Steeping kawa coffee leaves is a health drink that has strong antioxidant activity.
PEMERIKSAAN RESIDU ANTIBIOTIK PADA HATI KERBAU DAN IKAN NILA DENGAN METODA DIFUSI AGAR Musyirna Rahmah NST; Rahayu Utami; Nur Rahmadani Fitri
Jurnal Peternakan Vol 7, No 1 (2010): Februari 2010
Publisher : State Islamic University of Sultan Syarif Kasim Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24014/jupet.v7i1.466

Abstract

This study was aimed to identify antibiotic residue on buffalo liver (Bubalus bubalis) dan nila fish (Oreochromis niioticus). Detection of antibiotic residu was used antibacterial assay by diffusion methode. The result indicated that some of samP/i:.s at concentration 25% contained antibiotic residue with inhibited growth rate Escherichia coli 12,3 nun.
Molecular Docking and Molecular Dynamic Simulation of 1,5-Benzothiazepine Chalcone Derivative Compounds as Potential Inhibitors for Zika Virus Helicase Neni Frimayanti; Musyirna Rahmah Nasution; Elsa Etavianti
Jurnal Riset Kimia Vol. 12 No. 1 (2021): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v12i1.365

Abstract

Zika virus caused of the emerging infections characterized by fever, Guillain-Barré syndrome (GBS) for adults. In the current work, we aimed to study the binding orientation of 1,5-benzothiazepine compounds as new potential agent against Zika virus inhibitor through molecular docking and molecular dynamic simulation. Since, 1-5-Benzothiazepines are particular interest for drug discovery and they also has some biological activities. However, their antiviral activities and in silico studies of the binding to their biological targets have not been extensively investigated. Molecular docking study of 1,5-benzothiazepine chalcone derivatives compounds with protein target 5GJB (PDB ID) and this protein was taken from the crystallographic structure. In this study, twelve 1,5-benzothiazepine chalcone derivative compounds were docked to the protein with the grid box along x, y and z radius of 26.85, 28.17 and 24.43 Å, respectively. Suramin was used as positive control. Thus, it can be used as a reference for design new inhibitors for Zika virus helicase. Based on the docking results, it is observed that compounds MA3 and MA8 are estimated to have activity as inhibitors for Zika virus helicase with binding free energy values of -4.6490 and -4.9291 kcal/mol, respectively. MA3 and MA8 were also stable during the MD simulations with the hydrogen bonding are still maintained before and after MD simulation. Furthermore, both of these compounds can be used an early stage for drug design and drug delivery process.
Isolasi Dan Identifikasi Mikroba Penghasil Antibiotika Dari Sampel Lumpur Sungai Kampar Riau Musyirna Rahmah Nst; Akmal Djamaan; Gustina '
Ilmu Perairan (Aquatic Science) Vol 8, No 2 (2010)
Publisher : Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/jipas.8.2.p.1-11

Abstract

Isolation of microbes that produce antibiotic found in the sludge of Kamparriver has been carrie out using crowded plate method. The sludge were inoculated inPDA and NA, and incubated for 24 hours. Microbes showing clear zone wereobserved, this indicated the microbes produce antibiotics. The microbes wereisolated and identified. The result showed there were three species Bacillus sp ofwhich potencial to produce antibiotic compund.Key words: microbe, isolation,antibiotic
UJI POTENSI TABIR SURYA EKSTRAK ETANOL DAUN TENGGEK BURUNG (Euodia redlevi) SECARA IN VITRO musyirna rahmah nasution; Afrida Yeti; Bella Ardhiyati
JURNAL FARMASI DAN MAKANAN Vol 4 No 2 (2021): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v4i2.1764

Abstract

Daun tenggek burung (Euodia redlevi) secara tradisional digunakan untuk mengobati tekanan darah tinggi, melancarkan peredaran darah, mencegah penuaan dini, mengobati diabetes mellitus serta memberikan efek kebugaran.Daun tenggek burung merupakan salah satu tumbuhan obat yang mengandung diketahui mengandung senyawa fenolik yang berpotensi sebagai tabir surya.Tujuan dari penelitian ini untuk mengetahui aktivitas tabir surya pada ekstrak etanol daun tenggek burung dengan metode spektrofotometri.Pengujian aktivitas tabir surya dilakukan dengan menentukan nilai persentase Transmisi eritema (%Te), Transmisi pigmentasi (%Tp), dan Sun Protection Factor (SPF) menggunakan microplate reader. Berdasarkan hasil pengujian ekstrak etanol daun tenggek burung (Euodia redlevi) menunjukan aktivitas tabir surya yang baik pada konsentrasi 250 ppm dengan nilai %Te sebesar 0,4252% (Sunblock), nilai %Tp sebesar 0,3150% (Sunblock) dan nilai Sun Protection Factor (SPF) 21,624 (proteksi ultra).
AKTIVITAS INHIBISI α-GLUKOSIDASE INFUSA KAYU MANIS (Cinnamomum verum J.Presl), KUNYIT (Curcuma domestica Val) DAN KOMBINASINYA Wulan Desmar Utari; Musyirna Rahmah Nasution
JURNAL FARMASI DAN MAKANAN Vol 5 No 1 (2021): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v5i1.2145

Abstract

Pengobatan diabetes melitus khususnya tipe 2 biasanya diatasi menggunakan obat akarbose yang akan menginhibisi aktivitas enzim α-glukosidase, enzim α-glukosidase dalam proses pencernaan akan menghidrolisis amilum menjadi glukosa. Penelitian ini bertujuan untuk melihat potensi aktivitas inhibisi enzim α-glukosidase secara in vitro infusa tunggal dari kedua tanaman kayu manis (Cinnamomum verum J.Presl) dan Kunyit (Curcuma domestica Val) dan melihat apakah ada aktivitas sinergis terhadap kombinasi dari kedua infusa. % inhibisi infusa terhadap aktivitas glukosidase ditentukan menggunakan substrat p-nitrofenil-α-D-glukopiranosida (p-NPG). Absorbansi hasil reaksi diukur menggunakan microplate reader pada panjang gelombang 410 nm. Hasil Penelitian menunjukkan bahwa pada formula kombinasi infusa kayu manis dan kunyit memiliki efek sinergis dalam menginhibisi enzim α-glukosidase, akan tetapi tidak lebih baik dibanding dengan formula I infusa tunggal kayu manis yaitu % inhibisi sebesar 97,21 %, serta analisis one way ANOVA terhadap aktivitas enzim α-glukosidase dari semua formula memiliki perberbedan yang sangat nyata (p<0,05).
UJI AKTIVITAS ANTIBAKTERI EKTRAK ETANOL TIGA VARIETAS BIJI PEPAYA (Carica papaya L) TERHADAP BAKTERI Staphylococcus aureus, Staphylococcus epidermidis DAN Propionibacterium acnes Emma - Susanti
JURNAL FARMASI DAN MAKANAN Vol 5 No 1 (2021): Journal Of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v5i1.2233

Abstract

The seeds of papaya (Carica papaya L) can be used as traditional medicine. The first test of ethanol extract of papaya seeds obtained in the form of terpenoids and saponins. In Pekanbaru, there are three varieties of papaya, papaya callina, papaya honey and papaya palas. This research aims to determine the antibacterial activity of ethanol extract of three varieties of papaya seeds (Carica papaya L) against Staphylococcus aureus, Staphylococcus epidermidis and Propionibacterium acnes bacteria with disc diffusion method. Test results of ethanol extract of papaya varieties callina with the highest at concentration 80% inhibitory zone Staphylococcus epidermidis was 19.83 mm. Ethanol extract of papaya seeds varieties honey gave the highest inhibitory zone in Staphyloccous aureus at concentration 80% was 19,85 mm. While papaya seeds varieties palas gave the highest inhibitory zone in Staphylococcus epidermidis at concentration 80% was 19.70 mm. The variety that gives the highest inhibitory zone is the ethanol extract of papaya callina seeds on the Staphylococcus epidermidis
Isolasi dan Uji BSLT Ekstrak Etil Asetat Daun Meranti Sabut (Shore Ovalis (Korth.)) Enda Mora; Musyirna Rahma Nst; Emma Susanti; Arfan Zasliadi
Jurnal Sains Farmasi & Klinis Vol 1, No 2 (2015): J Sains Farm Klin 1(2), Mei 2015
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (716.592 KB) | DOI: 10.29208/jsfk.2015.1.2.34

Abstract

Isolation and test of Brine Shrimp Lethality Test (BSLT) of ethyl acetate extract of Shorea ovalis [Kort.]) leaves have been done. The isolation method used was column chromatography by Step Gradient Polarity (SGP). The aim of this research was to isolate the metabolite secondary compound and examine the activity test of Brine Shrimp Lethality Test (BSLT) from ethyl acetate extract of Shorea ovalis [Kort.]) leaves. The result showed that pure compound was I¬A which characterized by spectrum of IR, H-NMR, C-NMR, HSQC, HMBC and colour reaction of Liebermann-Burchard test. The characterization of the isolate was phytosterol with estimated molecular formula C27H48O. Result of BSLT test revealed that of ethyl acetat extract of meranti sabut leaves at 100, 10, and 1 ppm had value of LC50= 40.45 ppm with death of larva of Artemia salina equal to 56,6 % and was considered as very toxic.
Kekerabatan Genetik dan Indeks Resistensi Antibiotika Escherichia coli dari Air DAS Siak Provinsi Riau Yuli Haryani; Emma Susanti; Hexsha Rizki Amelia
Jurnal Sains Farmasi & Klinis Vol 6, No 2 (2019): J Sains Farm Klin 6(2), Agustus 2019
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (976.061 KB) | DOI: 10.25077/jsfk.6.2.141-146.2019

Abstract

Waterborne-disease masih memberikan angka prevalensi yang tinggi terutama di negara sedang berkembang. Keberadaan E. coli di perairan memberikan indikasi adanya cemaran pathogen dari feses hewan ataupun manusia. Penelitian ini bertujuan untuk menganalisa kekerabatan dan indeks resistensi antimikroba dari E.coli yang telah diisolasi dari DAS Siak, sungai terbesar yang melewati Provinsi Riau, yang masih digunakan oleh sebagian warga untuk aktivitas sehari-hari. Dendrogram yang dihasilkan dari gabungan 3 primer RAPD-PCR mampu membedakan tiap isolate uji. Intensitas penggunaan air sungai oleh warga dan kuatnya arus mempengaruhi distribusi mikroba indicator sanitasi tersebut dari Tapung hingga Perawang. Sifat resistensi antibiotika masih tergolong rendah (MAR index 0,142), namun eritromisin bukan merupakan antibiotika pilihan untuk diare akibat E.coli disebabkan seluruh isolate resisten terhadap antibiotika ini.
KONJUGASI ANHIDRAT KlORAMFENIKOL-PROTEIN (CAP-BSA DAN CAP-KLH) UNTUK PRODUKSI IgG DARI SERUM KELINCI Musyirna Rahmah Nst; Tri Budhi Murdiati
Sistem Informasi Vol 1 No 2 (2011): Jurnal Photon
Publisher : LPPM Universitas Muhammadiyah Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37859/jp.v1i2.113

Abstract

Dalam pengembangan metoda analisis residu antibiotik pada produk pangan hewani secara immunokimia telah dilakukan sintesis imunogen kloramfenikol (CAP) dengan protein Bovine Serum Albumin (BSA) dan Keyhole Limpet Hemocyanin (KLH) dengan metoda konjugasi mixed anhidrad. Hasil sintesis digunakan untuk produksi antibodi.Antigen dan antibodi yang dihasilkan dijadikan prangkat analisis residu antibiotik dengan Competitive Enzyme Linked Immunosorbent Assay (ELISA kompetitif). Hasil penelitian menunjukkan bahwa metoda konjugasi mixed anhidrad pada preparasi imunogen dengan jumlah CAP yang terkonjugasi ke grup amino bebas dari molekul protein BSA (CAP-BSA) adalah 18 unit dan ke protein KLH (CAP-KLH) adalah 782 unit. Antibodi poliklonal CAP-BSA dan CAP-KLH yang diproduksi dengan rata-rata kandungan IgG CAP-BSA 2,07 mg/ml dan IgG CAP-KLH 2,21 mg/ml.
Co-Authors -, Hasmalina ., Nofriyanti Abdi Wira Septama Abdifi, Reza Abrar Hafudz Qalbi Adinda Rusyamsi Afandi, Rifath Afnita, Fakhiratunnisa Afrida Yeti Agfa Febriyananda agistia, nesa Agistia, Nesa Agustini, Tiara Tri Akmal Djamaan Al Fadhilah, Shafira Alfian ) Alfitra Raisya alfitrah ramadhan Alimia Woelandri Amanda Putri Pratiwi Amnan, Wekis Raya Andarini Diharmi Andriani, Sindy Anggraini, Annisa Fitri Anita Lukman Anita Lukman Annisa Annisa Annisa Riski Permata Sari Antasya, Vaylia Aqilla, Alya Arfan Zasliadi Armon Fernando Arundita, Silvy Aulya, Nurliza Ayuni, Putri Azhari, Weriska Restu Azkia Wanudya Rahmadhani A’dilah, Nur Bella Ardhiyati Benni Iskandar Cahyani, Ardhia Regita Cindy Ayu Lestari Cindy Novia R Dasni Syafril Dasni Syafril Della Vasmawati Delvian Fikrani Deni Anggraini Denisya amanda Denisya Anggraini Depa Gloria Kristin Pardede Dessy Novita Sari Desvica Fitriyani Putri Dheanita Liana Dita Bina Julianti Habeahan Diwa, Resi Oktamara Dwi Andreyas Dwi Winarsih Elsa Etavianti Elsa Safitri Elvi Nurjannah Emrizal Enda Mora Enda Mora Etavianti, Elsa Fadiyah Yueflen Fahri, Elifia Cahyani Fahriza, Mela Febrian, Dyan Felycia Wardi Ferdy Firmansyah Fharisti Kirana Fina Aryani, Fina Firman Nugroho Fitri, Ramadini Fitri, Valentina Furi, Mustika Ginta Rio Maranti Gressy Novita Gustina &#039; Hafizah, Afrah Haiyul Fadhli Hanifa, Dhea Hanifa, Elvi Hasmalina - Hasmalina Nasution Hexsha Rizki Amelia Husnawati Ihksani, Nurul Ihsan Ikhtiaruddin Ihsan Ikhtiarudin Intan Putri Utami Jannah, Ninuk Rodhiatul Kamalrullah ) Kiranti Azlin Kolista Sisilawati Kolista Sisilawati Ladiona, Maria Yella Lamun Bathara Larasati Arsad Lilik Septiana Manik, Dhea Putri Bertuah Br Maria Yella Ladiona Marli, Nofrita Martina Br Manullang Masnun, Lidiatil Mayrade, Salma Yudhistira Mega Fatimah Rosana Meiriza Djohari, Meiriza Melati, Putri Melzi Octaviani Mery Sukmiwati Milianty, Jesy Mira Febriana Musyirna Rahma Nst musyirna Rahmah Muthmainnah, Nurillah Nabilah, Clara Nabilla, Vivi Gita Nanang Nasution, Tio Afandi Neni Frimayanti Ningrum, Tilar Eka Widia Ningsih, Yozi Fiedya Nofriyanti - Novianti, Yetri Nur Rahmadani Fitri Nuraina, Nuraina Nurhapipah, Nurhapipah Octavia, Richa Pardede, Depa Gloria Kristin Peng-Wei, Ching Pratiwi, Erniza Putri Binti Jakfar Putri Lestari, Putri Putri Putri, Putri R. Rizatita Fitriani Rabiatul Adawiyah Rahayu Utami Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahma Dona Rahman, Sumiati Raja Adli Husein Raja adli husin Rajeb Fadillah ramadhan, alfitrah Ramadhani, Ayu Indah Ramadhani, Elsha Fadhika Dwi Ramanda safitri Ratna Sari Dewi Reza Abdifi Rizda Fitriani Robiatun Rambe Roli Oktaviana Ronapadua Sahara Ruska, Shinta Liana S.Farm., M.Farm., Apt, Sondang Khairani Safitri, Ramanda Safli, Fazza Aulia Sahara, Ronapadua Sakinah, Norma Salsabila alhamdania Balqis Salsabila Zahirah Ananda Saryono Saryono Selvi Aulia Wibowo Septi Muharni Serlin Partika Sari Silalahi, Rizka Fitri Silvera Devi Silvy Arundita Simanjuntak, Asnika Putri Siti Nurhaliza Sri Hardianti Sudarsi, Yulisma Suhelmi - Suhelmi - Sumiati Rahman Susi lestari - Syahbandi, Ilham Syamira Syaputri, Rezy Tambunan, Beatrix Evalin Titania T Nugroho Tri Budhi Murdiati Tri Budhi Murdiati Tria Halianti Triani, Leni Ulfa, Rodia Vaylia Antasya Wardi, Felycia Wei-Ching Peng Winda Sri Wahyuni Wira Noviana, Wira Noviana Wulan Desmar Utari Wulan, Nimas Yuharmen - Yuli Haryani Yulisma Sudarsi Yunelva, Rinda Zulmai Rani